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$562+ Cheap flights from Des Moines (DSM) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/6. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SCL
feb. 25 — mar. 41
mar. 2/25
mar. 3/4
1 adult, Economy
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Cheap flight deals from Des Moines to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated febrero 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$890
(LATAM Airlines)

One-way from

$562
(Yatra.com)
Provider with most accurate pricing for Des Moines-Santiago Arturo Merino Benitez flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Santiago Arturo Merino Benitez flights.
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From Des Moines to Santiago Arturo Merino Benitez
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One-way flight from Des Moines to Santiago Arturo Merino Benitez
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Find flight deals from Des Moines to Santiago

Cheapest flights from Des Moines to Santiago
Explore the most affordable flight options available from Des Moines to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on febrero 20, 2025.

This LATAM Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/92:14 pmDSM - SCL
1 stop15h 46mLATAM Airlines
mié. 5/148:40 pmSCL - DSM
1 stop14h 36mLATAM Airlines
Deal found 2/20$890
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/92:14 pmDSM - SCL
1 stop15h 46mDelta
mar. 5/1312:30 amSCL - DSM
2 stops22h 54mDelta
Deal found 2/20$1,022
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 4/68:03 amDSM - SCL
3 stops43h 12mMultiple Airlines
sáb. 4/122:30 amSCL - DSM
3 stops36h 30mMultiple Airlines
Deal found 2/19$1,032
This Gotogate deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 4/67:45 amDSM - SCL
2 stops20h 19mCopa Airlines
sáb. 4/1212:30 amSCL - DSM
2 stops18h 36mCopa Airlines
Deal found 2/20$2,136

Find flights from Des Moines to Santiago within your budget

Customize your flight search to find flights from Des Moines to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated febrero 20, 2025.

Fly from

Des Moines

Fly to

Santiago

Route

Depart

Return

Price

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

vie. 5/9

2:14 pm-7:00 am

1 stop15h 46m

Santiago Arturo Merino Benitez

mié. 5/14

8:40 pm-10:16 am

1 stop14h 36m

$890

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

vie. 5/9

2:14 pm-7:00 am

1 stop15h 46m

Santiago Arturo Merino Benitez

mar. 5/13

12:30 am-10:24 pm

2 stops22h 54m

$1,022

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

dom. 4/6

8:03 am-4:15 am

3 stops43h 12m

Santiago Arturo Merino Benitez

sáb. 4/12

2:30 am-2:00 pm

3 stops36h 30m

$1,032

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

dom. 4/6

7:45 am-5:04 am

2 stops20h 19m

Santiago Arturo Merino Benitez

sáb. 4/12

12:30 am-6:06 pm

2 stops18h 36m

$2,136

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

dom. 4/6

6:20 am-6:00 am

2 stops46h 40m

$562

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

dom. 4/6

11:27 am-7:00 am

1 stop18h 33m

$583

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/19

Compare providers for flights from Des Moines to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Santiago in February.
ProviderPrice AccuracyTrust Score*
AranGrantPrice Accuracy3 starsTrust Score*1 star
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Des Moines to Santiago

Get recent, data-driven insights about flights from Des Moines to Santiago including ideal travel times, pricing trends, and more.

Rainfall in Santiago by month

Plan your trip to Santiago by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Santiago ranges from 0.0 - 2.8 inches per month. June is typically the wettest month, when rainfall can reach 2.8 in. January is typically the driest time to visit Santiago when rainfall is around 0.0 in.

Temperature in Santiago by month

Plan your trip to Santiago by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Santiago, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 69.8 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated febrero 20, 2025.
Delta
8.0
Very good
8,219 reviews

Boarding

8.2

Entertainment

7.9

Comfort

8.0

Crew

8.5

Food

7.3

Overall

8.0

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta
8.0
Very good
8,219 reviews
Delta
8.0
Very good
8,219 reviews

Boarding

8.2

Entertainment

7.9

Comfort

8.0

Crew

8.5

Food

7.3

Overall

8.0

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Copa Airlines
7.6
Good
1,510 reviews
Delta
8.0
Very good
8,219 reviews

Boarding

8.2

Entertainment

7.9

Comfort

8.0

Crew

8.5

Food

7.3

Overall

8.0

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

LATAM Airlines
7.5
Good
1,795 reviews
Delta
8.0
Very good
8,219 reviews

Boarding

8.2

Entertainment

7.9

Comfort

8.0

Crew

8.5

Food

7.3

Overall

8.0

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Des Moines to Santiago round-trip?

    Currently priced at $890, LATAM Airlines will fly you from Des Moines to Santiago and back. In addition to LATAM Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Delta and Copa Airlines - these airlines can fly you to your destination from $1,022 and $2,136, respectively.

  • Can I find deals for flights from Des Moines to Santiago that include hotel bookings?

    Yes. In addition to deals on Des Moines to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Santiago.

  • Can I find deals for business class flights from Des Moines to Santiago?

    Yes. Cheapflights offers flight deals from Des Moines to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Des Moines to Santiago (average of $752). Flying from Des Moines to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Des Moines to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Des Moines to Santiago

Discover the top 2 airlines that operate flights from Des Moines to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated febrero 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$742Average$1,349FlexibilityNo cancel feeOn-time71%
DeltaCheapest$782Average$958FlexibilityNo cancel feeOn-timeN/A
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