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$349+ Cheap flights from Denver (DEN) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/1. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — SCL
Apr 8 — Apr 151
Tue 4/8
Tue 4/15
1 adult, Economy
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Find cheap flights from Denver to Santiago with Cheapflights

1. Tell us where you want to go

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Cheapflights Tip: The best prices from Denver Intl to Santiago Arturo Merino Benitez are usually found in April or October, booked 66 days in advance, depart on a Tuesday or Monday and return on a Tuesday

Cheap flight deals from Denver to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Denver (DEN) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 3, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$622
(KAYAK)

One-way from

$349
(Kiwi.com)

Popular in

December

Cheapest in

April

Average price

$753
Provider with most accurate pricing for Denver Intl-Santiago Arturo Merino Benitez flight deals.
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Provider most trusted by Cheapflights users for Denver Intl-Santiago Arturo Merino Benitez flights.
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From Denver Intl to Santiago Arturo Merino Benitez
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One-way flight from Denver Intl to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 8% potential increase in price ($77 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($26 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Denver to Santiago

Cheapest flights from Denver to Santiago
Explore the most affordable flight options available from Denver to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 3, 2025.

This KAYAK deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2210:42 pmDEN - SCL
1 stop22h 26mCopa Airlines
Thu 8/284:10 amSCL - DEN
1 stop15h 53mCopa Airlines
Deal found 4/2$622
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/69:25 amDEN - SCL
1 stop18h 25mAmerican Airlines
Mon 11/1711:45 pmSCL - DEN
1 stop13h 37mAmerican Airlines
Deal found 3/31$634
This Aeromexico deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/111:22 pmDEN - SCL
1 stop27h 53mAeromexico
Mon 11/2411:25 pmSCL - DEN
1 stop16h 25mAeromexico
Deal found 4/1$745
This Cheapflightsfares deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/287:20 amDEN - SCL
1 stop21h 40mLATAM Airlines
Tue 5/1310:45 pmSCL - DEN
1 stop21h 34mLATAM Airlines
Deal found 3/31$750
This Delta deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/126:30 amDEN - SCL
1 stop20h 30mDelta
Mon 11/2411:15 pmSCL - DEN
1 stop19h 43mDelta
Deal found 4/1$754
This LATAM Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/811:59 pmDEN - SCL
1 stop28h 51mMultiple Airlines
Sat 8/1610:45 pmSCL - DEN
1 stop21h 28mMultiple Airlines
Deal found 4/2$766

Cheapflights Fare Finder

Customize your flight search to find flights from Denver to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 3, 2025.
Use the filters below to find and compare flights from Denver to Santiago that are best for you.

Fly from

Denver

Fly to

Santiago

Route

Depart

Return

Price

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Fri 8/22

10:20 pm-10:44 pm

1 stop22h 24m

Santiago Arturo Merino Benitez

Sun 8/31

4:10 am-6:03 pm

1 stop15h 53m

$622

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Fri 8/22

2:20 pm-7:05 am

1 stop14h 45m

Santiago Arturo Merino Benitez

Sat 8/30

9:55 pm-10:55 am

1 stop15h 00m

$654

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Mon 4/28

7:20 am-7:00 am

1 stop21h 40m

Santiago Arturo Merino Benitez

Tue 5/13

10:45 pm-6:19 pm

1 stop21h 34m

$750

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Mon 4/28

6:00 am-4:45 am

2 stops20h 45m

Santiago Arturo Merino Benitez

Tue 5/13

4:55 pm-12:42 pm

2 stops21h 47m

$754

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Fri 8/8

11:59 pm-6:50 am

1 stop28h 51m

Santiago Arturo Merino Benitez

Sat 8/16

10:45 pm-6:13 pm

1 stop21h 28m

$766

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Fri 8/22

8:05 am-1:25 pm

2 stops27h 20m

Santiago Arturo Merino Benitez

Fri 8/29

1:55 am-6:02 pm

2 stops42h 07m

$1,126

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Sun 6/1

12:15 pm-1:25 pm

3 stops47h 10m

$349

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Thu 4/17

1:30 pm-7:00 am

1 stop15h 30m

$512

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Wed 4/16

12:01 pm-6:45 am

1 stop16h 44m

$513

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Thu 4/17

10:25 pm-7:24 pm

1 stop18h 59m

$1,726

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/31

Compare providers for flights from Denver to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Denver to Santiago in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy3 starsTrust Score*1 star
CheapfaremartPrice Accuracy-Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Denver-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Denver-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Denver-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Denver-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Denver-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Denver to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Denver with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Denver to Santiago

How far ahead should I book a flight from Denver to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Denver to Santiago. Price data was last updated on March 28, 2025.

The price you pay for your flight from Denver to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 66 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Denver to Santiago?

Currently, April is the cheapest month in which you can book a flight from Denver to Santiago (average of $752). Flying from Denver to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DEN to SCL?

Find hourly flight availability from Denver to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 3, 2025.

When flying from Denver to Santiago, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 17% versus a flight in the morning.

What is the cheapest day to fly from Denver to Santiago?

Use this chart to determine the cheapest time to fly round-trip from Denver to Santiago. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Denver to Santiago flight should consider departing on Monday afternoons when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Rainfall in Santiago by month

Plan your trip to Santiago by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Santiago ranges from 0.0 - 2.8 inches per month. June is typically the wettest month, when rainfall can reach 2.8 in. January is typically the driest time to visit Santiago when rainfall is around 0.0 in.

Temperature in Santiago by month

Plan your trip to Santiago by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Santiago, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 69.8 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated April 3, 2025.
To help decide which airline to fly from Denver to Santiago, see what other customers have to say about Delta, Copa Airlines and LATAM Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,897 reviews

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,897 reviews
Delta
8.0
Very good
7,897 reviews

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.6
Good
1,400 reviews
Delta
8.0
Very good
7,897 reviews

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
LATAM Airlines
7.5
Good
1,754 reviews
Delta
8.0
Very good
7,897 reviews

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,897 reviews

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Avianca
6.7
Okay
2,304 reviews
Delta
8.0
Very good
7,897 reviews

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Denver to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Denver to Santiago round-trip?

    Currently priced at $622, Copa Airlines will fly you from Denver to Santiago and back. In addition to Copa Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from American Airlines and LATAM Airlines - these airlines can fly you to your destination from $654 and $750, respectively. Copa Airlines is currently priced 29% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Denver to Santiago one-way?

    To fly one-way, consider booking your trip with LATAM Airlines, which is currently one of the cheapest options available, starting at $512. Delta flights start at $513 while deals on Copa Airlines start at $1,726 one-way.

  • Can I find deals for flights from Denver to Santiago that include hotel bookings?

    Yes. In addition to deals on Denver to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Denver to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to Santiago.

  • Can I find deals for business class flights from Denver to Santiago?

    Yes. Cheapflights offers flight deals from Denver to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Denver to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Denver to Santiago (average of $752). Flying from Denver to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Denver to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
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Denver to Easter Island flights
Grand Junction to Santiago flights
Montrose to Santiago flights
Denver to La Serena flights
Denver to Temuco flights

Top 6 airlines flying from Denver to Santiago

Discover the top 6 airlines that operate flights from Denver to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$592Average$845FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$601Average$890FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$621Average$789FlexibilityNo cancel feeOn-time70%
DeltaCheapest$752Average$892FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$752Average$895FlexibilityNo cancel feeOn-time81%
AeromexicoCheapest$803Average$1,006FlexibilityNo cancel feeOn-timeN/A

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