What are the cheapest airlines flying from Chicago to Santiago round-trip?

According to our current data, Avianca ($534), Copa Airlines ($792), and LATAM Airlines ($796) offers the cheapest pricing from Chicago to Santiago. Avianca is 40% cheaper than the average price of flights available within the next 90 days to this destination.

What are the cheapest airlines to fly from Chicago to Santiago one-way?

To fly one-way, consider booking your trip with Avianca, which is currently one of the cheapest options available, starting at $230. Delta flights start at $458 while deals on LATAM Airlines start at $472 one-way.

What are the most popular airlines that fly from Chicago to Santiago?

When booking a flight from Chicago to Santiago, you may want to consider flying on American Airlines, Air Canada or Avianca as they are the most popular for this route.

What is the cheapest day to fly round-trip from Chicago to Santiago?

Sunday is generally a great day to depart. Flying on this day could help you save up to 17%.

How far in advance should I book a flight from Chicago to Santiago?

When searching for a good deal, it’s best to be prepared for potential fluctuations in price. We recommend booking at least 23 days in advance, which can save you up to 60% on flights from Chicago to Santiago compared to booking the week you need them. Waiting 23 days out may not be for everyone, so we have options available for flights within the next two weeks, with the lowest price starting at $547. For sooner than that we have options available in the next 3 days from $895.

What is the cheapest month to fly from Chicago to Santiago?

Due to multiple factors, expect to potentially pay more when booking in December. For low rates, April can be a great choice for travel to Santiago. Flights to Santiago from Chicago in April are about $904 on average during April, but can be found for as low as $605.

Most accurate provider : When it comes to deals on Chicago-Santiago flights, users find the pricing of AranGrant to be most consistent on Cheapflights vs. AranGrant Users can find the same prices on Chicago-Santiago flight deals on Cheapflights vs. AranGrant >95% of the time. Price accuracy is based on data collected from Chicago-Santiago flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Chicago-Santiago flights, Cheapflights users trust AranGrant the most. AranGrant has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

What airport do you fly into for flights to Santiago from Chicago?

For a flight from Chicago to Santiago, you will be flying into Arturo Merino Benitez. Santiago Arturo Merino Benitez (SCL) is just 8.4 mi from the center of the city. Arturo Merino Benitez is the only Santiago airport and it handles 0 inbound flights from Chicago per day. 7 airlines have flights to Santiago Arturo Merino Benitez from Chicago on a regular basis.

Can I find deals for flights from Chicago to Santiago that include hotel bookings?

Yes. In addition to deals on Chicago to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Chicago to Santiago?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Chicago to Santiago.

Can I find deals for business class flights from Chicago to Santiago?

Yes. Cheapflights offers flight deals from Chicago to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$230+ Flights from Chicago to Santiago - Compare & Save Big

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1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

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Cheapflights Tip: The best prices from Chicago to Santiago Arturo Merino Benitez are usually found in April or October, booked 22 days in advance, depart on a Monday or Wednesday and return on a Monday

Cheap flight deals from Chicago to Santiago

Most accurate provider	AranGrant 3 stars
Most trusted provider	AranGrant 3 stars
Round-trip from	$534 (Priceline)
One-way from	$230 (Yatra.com)
Popular in	December
Cheapest in	April
Average price	$666

Provider with most accurate pricing for Chicago (CHI)-Santiago Arturo Merino Benitez flight deals.

Search Deals

Provider most trusted by Cheapflights users for Chicago (CHI)-Santiago Arturo Merino Benitez flights.

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From Chicago (CHI) to Santiago Arturo Merino Benitez

Search Deals

One-way flight from Chicago (CHI) to Santiago Arturo Merino Benitez

Search Deals

Highest demand for flights based on searches. 7% potential increase in price ($75 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 3% potential price decrease ($31 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in April 2025

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Find flight deals from Chicago to Santiago

Cheapest flights from Chicago to Santiago
Explore the most affordable flight options available from Chicago to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 25, 2025.

Wed 7/163:45 pmORD - SCL

2 stops29h 45mAvianca

Tue 8/52:30 pmSCL - ORD

3 stops24h 55mAvianca

Deal found 4/25

$534

Mon 6/92:35 pmORD - SCL

1 stop21h 50mMultiple Airlines

Sun 6/153:35 amSCL - ORD

2 stops19h 21mMultiple Airlines

Deal found 4/25

$655

Mon 8/47:54 amORD - SCL

1 stop20h 10mCopa Airlines

Mon 8/112:23 amSCL - ORD

1 stop22h 59mCopa Airlines

Deal found 4/25

$792

Mon 9/811:00 amORD - SCL

2 stops17h 50mLATAM Airlines

Mon 9/2212:25 amSCL - ORD

2 stops20h 31mLATAM Airlines

Deal found 4/25

$796

Thu 10/910:35 amMDW - SCL

2 stops18h 05mLATAM Airlines

Wed 10/1512:25 amSCL - MDW

2 stops19h 33mLATAM Airlines

Deal found 4/25

$804

Thu 10/309:30 amORD - SCL

1 stop19h 30mDelta

Thu 11/67:55 amSCL - ORD

2 stops18h 58mDelta

Deal found 4/24

$804

Thu 10/303:40 pmMDW - SCL

1 stop13h 20mDelta

Thu 11/610:50 pmSCL - MDW

2 stops16h 42mDelta

Deal found 4/24

$808

Wed 10/13:33 pmORD - SCL

2 stops14h 32mAmerican Airlines

Fri 10/109:55 pmSCL - ORD

2 stops19h 57mAmerican Airlines

Deal found 4/25

$808

Sun 6/86:30 amMDW - SCL

2 stops23h 15mMultiple Airlines

Sun 6/159:45 amSCL - MDW

1 stop35h 32mMultiple Airlines

Deal found 4/25

$881

Best flights from Chicago to Santiago
Discover carefully curated flight deals from Chicago to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 25, 2025.

Wed 7/163:45 pmORD - SCL

2 stops29h 45mAvianca

Tue 8/52:30 pmSCL - ORD

3 stops24h 55mAvianca

Deal found 4/25

$534

Mon 6/92:35 pmORD - SCL

1 stop21h 50mMultiple Airlines

Sun 6/153:35 amSCL - ORD

2 stops19h 21mMultiple Airlines

Deal found 4/25

$655

Mon 8/47:54 amORD - SCL

1 stop20h 10mCopa Airlines

Mon 8/112:23 amSCL - ORD

1 stop22h 59mCopa Airlines

Deal found 4/25

$792

Mon 9/811:00 amORD - SCL

2 stops17h 50mLATAM Airlines

Mon 9/2212:25 amSCL - ORD

2 stops20h 31mLATAM Airlines

Deal found 4/25

$796

Thu 9/259:30 amORD - SCL

2 stops17h 00mDelta

Tue 10/148:15 amSCL - ORD

2 stops17h 38mDelta

Deal found 4/24

$804

Wed 10/19:55 amORD - SCL

1 stop20h 10mAmerican Airlines

Fri 10/109:55 pmSCL - ORD

2 stops19h 57mAmerican Airlines

Deal found 4/25

$808

Thu 10/910:35 amMDW - SCL

2 stops18h 05mLATAM Airlines

Wed 10/1512:25 amSCL - MDW

2 stops19h 33mLATAM Airlines

Deal found 4/25

$804

Tue 7/151:05 pmMDW - SCL

1 stop16h 55mDelta

Tue 8/58:40 pmSCL - MDW

1 stop16h 15mDelta

Deal found 4/25

$874

Sun 6/86:30 amMDW - SCL

2 stops23h 15mMultiple Airlines

Sun 6/159:45 amSCL - MDW

1 stop35h 32mMultiple Airlines

Deal found 4/25

$881

Last-minute flights from Chicago to Santiago
Discover last-minute flight deals from Chicago to Santiago. Data last updated April 25, 2025 and is based on user searches.

Sun 4/275:43 pmORD - SCL

2 stops21h 57mLATAM Airlines

Tue 4/297:15 amSCL - ORD

2 stops17h 44mLATAM Airlines

Deal found 4/24

$960

Wed 5/74:15 pmMDW - SCL

1 stop13h 45mLATAM Airlines

Sat 5/1012:13 pmSCL - MDW

2 stops22h 27mLATAM Airlines

Deal found 4/24

$999

Thu 5/81:19 pmMDW - SCL

2 stops47h 06mMultiple Airlines

Sun 5/118:40 pmSCL - MDW

1 stop14h 00mMultiple Airlines

Deal found 4/25

$898

Mon 5/192:35 pmORD - SCL

1 stop12h 40mAvianca

Mon 6/211:55 pmSCL - ORD

1 stop14h 20mAvianca

Deal found 4/24

$640

Mon 5/197:54 amORD - SCL

1 stop13h 50mCopa Airlines

Sun 6/12:24 amSCL - ORD

1 stop23h 10mCopa Airlines

Deal found 4/24

$1,007

Mon 5/196:38 pmMDW - SCL

2 stops16h 47mDelta

Mon 6/211:05 pmSCL - MDW

2 stops17h 15mDelta

Deal found 4/24

$1,026

Mon 5/191:30 pmORD - SCL

1 stop16h 15mDelta

Sat 5/2412:30 amSCL - ORD

2 stops19h 18mDelta

Deal found 4/24

$1,204

Tue 5/206:10 amORD - SCL

1 stop19h 25mMultiple Airlines

Tue 5/274:51 amSCL - ORD

2 stops33h 24mMultiple Airlines

Deal found 4/24

$784

One-way flights from Chicago to Santiago
Search for one-way flight options from Chicago to Santiago. Find affordable one-way fares based on user searches. Data last updated April 25, 2025.

Sun 6/83:45 pmORD - SCL

2 stops35h 30mAvianca

Deal found 4/24

$230

Sat 6/149:12 pmMDW - SCL

2 stops30h 03mMultiple Airlines

Deal found 4/25

$295

Mon 6/27:47 amORD - SCL

2 stops19h 28mMultiple Airlines

Deal found 4/25

$303

Tue 8/1210:35 amMDW - SCL

2 stops15h 55mDelta

Deal found 4/25

$458

Tue 7/291:16 pmORD - SCL

1 stop16h 44mDelta

Deal found 4/24

$458

Mon 8/251:05 pmMDW - SCL

1 stop16h 55mLATAM Airlines

Deal found 4/25

$472

Wed 5/71:30 pmORD - SCL

2 stops22h 35mLATAM Airlines

Deal found 4/25

$625

Cheapflights Fare Finder

Use the filters below to find and compare flights from Chicago to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Wed 7/16

3:45 pm-10:30 pm

2 stops29h 45m

Santiago Arturo Merino Benitez

Tue 8/5

2:30 pm-2:25 pm

3 stops24h 55m

$534

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Mon 6/9

2:35 pm-1:25 pm

1 stop21h 50m

Santiago Arturo Merino Benitez

Sun 6/15

3:35 am-9:56 pm

2 stops19h 21m

$655

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Mon 8/4

7:54 am-5:04 am

1 stop20h 10m

Santiago Arturo Merino Benitez

Mon 8/11

2:23 am-12:22 am

1 stop22h 59m

$792

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Mon 9/8

11:00 am-6:50 am

2 stops17h 50m

Santiago Arturo Merino Benitez

Mon 9/22

12:25 am-6:56 pm

2 stops20h 31m

$796

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Thu 9/25

9:30 am-4:30 am

2 stops17h 00m

Santiago Arturo Merino Benitez

Tue 10/14

9:40 pm-12:08 pm

1 stop16h 28m

$804

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Thu 10/9

10:35 am-6:40 am

2 stops18h 05m

Santiago Arturo Merino Benitez

Wed 10/15

12:25 am-5:58 pm

2 stops19h 33m

$804

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Wed 10/1

3:33 pm-8:05 am

2 stops14h 32m

Santiago Arturo Merino Benitez

Fri 10/10

9:55 pm-3:52 pm

2 stops19h 57m

$808

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Tue 7/15

1:05 pm-7:00 am

1 stop16h 55m

Santiago Arturo Merino Benitez

Tue 8/5

8:40 pm-11:55 am

1 stop16h 15m

$874

ChicagoSantiago

MDW - SCL

MDWSCL

Chicago Midway

Sun 6/8

6:30 am-6:45 am

2 stops23h 15m

Santiago Arturo Merino Benitez

Sun 6/15

9:45 am-8:17 pm

1 stop35h 32m

$881

ChicagoSantiago

ORD - SCL

ORDSCL

Chicago O'Hare Intl

Sun 6/8

3:45 pm-4:15 am

2 stops35h 30m

$230

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/24

Showing 1-10 of 16 results

Compare providers for flights from Chicago to Santiago

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Chicago to Santiago in April.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy1 star	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*2 stars
eDreams	Price Accuracy3 stars	Trust Score*3 stars
AranGrant	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Chicago-Santiago flights, users find the pricing of AranGrant to be most consistent on Cheapflights vs. AranGrant Users can find the same prices on Chicago-Santiago flight deals on Cheapflights vs. AranGrant >95% of the time. Price accuracy is based on data collected from Chicago-Santiago flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Chicago-Santiago flights, Cheapflights users trust AranGrant the most. AranGrant has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Chicago to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Chicago with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago to Santiago

How far ahead should I book a flight from Chicago to Santiago?

The price you pay for your flight from Chicago to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 22 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Chicago to Santiago?

Currently, April is the cheapest month in which you can book a flight from Chicago to Santiago (average of $752). Flying from Chicago to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHI to SCL?

When flying from Chicago to Santiago, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 11% versus a flight in the afternoon.

What is the cheapest day to fly from Chicago to Santiago?

Travelers seeking maximum savings on their Chicago to Santiago flight should consider departing on Monday at noon when fares are most often at their lowest. Monday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Rainfall in Santiago by month

In terms of precipitation, rainfall in Santiago ranges from 0.0 - 2.8 inches per month. June is typically the wettest month, when rainfall can reach 2.8 in. January is typically the driest time to visit Santiago when rainfall is around 0.0 in.

Temperature in Santiago by month

If weather is an important factor for your trip to Santiago, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 69.8 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Santiago

Peruse reviews from past customers who have flown with Delta, Copa Airlines and LATAM Airlines from Chicago to Santiago to help guide your decision. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,920 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta

8.0

Very good

7,920 reviews

Delta

8.0

Very good

7,920 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Copa Airlines

7.6

Good

1,411 reviews

Delta

8.0

Very good

7,920 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

LATAM Airlines

7.5

Good

1,767 reviews

Delta

8.0

Very good

7,920 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,920 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Avianca

6.7

Okay

2,317 reviews

Delta

8.0

Very good

7,920 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

What airport do you fly into for flights to Santiago from Chicago?
For a flight from Chicago to Santiago, you will be flying into Arturo Merino Benitez. Santiago Arturo Merino Benitez (SCL) is just 8.4 mi from the center of the city. Arturo Merino Benitez is the only Santiago airport and it handles 0 inbound flights from Chicago per day. 7 airlines have flights to Santiago Arturo Merino Benitez from Chicago on a regular basis.
What are the cheapest airlines flying from Chicago to Santiago round-trip?
According to our current data, Avianca ($534), Copa Airlines ($792), and LATAM Airlines ($796) offers the cheapest pricing from Chicago to Santiago. Avianca is 40% cheaper than the average price of flights available within the next 90 days to this destination.
What are the cheapest airlines to fly from Chicago to Santiago one-way?
To fly one-way, consider booking your trip with Avianca, which is currently one of the cheapest options available, starting at $230. Delta flights start at $458 while deals on LATAM Airlines start at $472 one-way.
Can I find deals for flights from Chicago to Santiago that include hotel bookings?
Yes. In addition to deals on Chicago to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Chicago to Santiago?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Chicago to Santiago.
Can I find deals for business class flights from Chicago to Santiago?
Yes. Cheapflights offers flight deals from Chicago to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Chicago to Santiago?
Currently, April is the cheapest month in which you can book a flight from Chicago to Santiago (average of $752). Flying from Chicago to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Chicago to Santiago

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Top 7 airlines flying from Chicago to Santiago

Airline	Cheapest	Average	Flexibility	On-time
Avianca	Cheapest$512	Average$698	FlexibilityNo cancel fee	On-time71%
Copa Airlines	Cheapest$620	Average$898	FlexibilityNo cancel fee	On-time70%
Air Canada	Cheapest$707	Average$951	FlexibilityNo cancel fee	On-time67%
American Airlines	Cheapest$750	Average$993	FlexibilityNo cancel fee	On-time71%
LATAM Airlines	Cheapest$772	Average$998	FlexibilityNo cancel fee	On-time81%
United Airlines	Cheapest$782	Average$982	FlexibilityNo cancel fee	On-time69%
Delta	Cheapest$792	Average$956	FlexibilityNo cancel fee	On-timeN/A

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$230+ Cheap flights from Chicago (CHI) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/8. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Chicago to Santiago with Cheapflights

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3. Compare prices and book

Cheapflights Tip: The best prices from Chicago to Santiago Arturo Merino Benitez are usually found in April or October, booked 22 days in advance, depart on a Monday or Wednesday and return on a Monday

Cheap flight deals from Chicago to Santiago

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Chicago to Santiago

Cheapest flights from Chicago to SantiagoExplore the most affordable flight options available from Chicago to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 25, 2025.

Explore the most affordable flight options available from Chicago to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 25, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Chicago to Santiago that are best for you.

Compare providers for flights from Chicago to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Chicago to Santiago in April.

Best time to book a flight from Chicago to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Chicago with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Chicago to Santiago

How far ahead should I book a flight from Chicago to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Chicago to Santiago. Price data was last updated on April 18, 2025.

What is the cheapest month to book a flight from Chicago to Santiago?

What is the cheapest time of day to fly from CHI to SCL?

Find hourly flight availability from Chicago to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 25, 2025.

What is the cheapest day to fly from Chicago to Santiago?

Use this chart to determine the cheapest time to fly round-trip from Chicago to Santiago. Price data was last updated on December 16, 2024.

Rainfall in Santiago by month

Plan your trip to Santiago by taking into account the average rainfall totals by month.

Temperature in Santiago by month

Plan your trip to Santiago by taking into account the average temperature totals by month.

Reviews of airlines servicing Santiago

Related info for your journey

Find useful and relevant information for your journey from Chicago to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Santiago from Chicago?

What are the cheapest airlines flying from Chicago to Santiago round-trip?

What are the cheapest airlines to fly from Chicago to Santiago one-way?

Can I find deals for flights from Chicago to Santiago that include hotel bookings?

How can I find direct flights from Chicago to Santiago?

Can I find deals for business class flights from Chicago to Santiago?

What is the cheapest month to book a flight from Chicago to Santiago?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Chicago to Santiago

See prices for flight routes from nearby airports that may be better suited for you.

Top 7 airlines flying from Chicago to Santiago

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Cheapest flights from Chicago to Santiago
Explore the most affordable flight options available from Chicago to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 25, 2025.