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Santa Cruz de la Sierra

$209+ Cheap flights from Key Largo, FL to Santa Cruz de la Sierra (VVI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/6. Fares are subject to change and may not be available on all flights or dates of travel.
MIA — VVI
Apr 7 — Apr 141
Mon 4/7
Mon 4/14
1 adult, Economy
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Cheapflights Tip: The best prices from Key Largo to Santa Cruz de la Sierra Viru Viru Intl are usually found in April or May, booked 85 days in advance, depart on a Thursday or Tuesday and return on a Friday

Cheap flight deals from Key Largo to Santa Cruz de la Sierra

Keep the following information in mind while searching for Key Largo to Santa Cruz de la Sierra flight deals. Data was last updated April 2, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$454
(Gotogate)

One-way from

$209
(Priceline)

Popular in

December

Cheapest in

April

Average price

$562
Provider with most accurate pricing for Miami-Santa Cruz de la Sierra Viru Viru Intl flight deals.
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Provider most trusted by Cheapflights users for Miami-Santa Cruz de la Sierra Viru Viru Intl flights.
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From Key Largo to Santa Cruz de la Sierra Viru Viru Intl
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One-way flight from Key Largo to Santa Cruz de la Sierra Viru Viru Intl
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Highest demand for flights based on searches. 6% potential increase in price ($47 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($12 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Key Largo to Santa Cruz de la Sierra

Cheapest flights from Key Largo to Santa Cruz de la Sierra
Explore the most affordable flight options available from Key Largo to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 2, 2025.

This Gotogate deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/95:00 pmMIA - VVI
1 stop8h 50mAvianca
Sun 7/62:55 amVVI - MIA
1 stop9h 35mAvianca
Deal found 4/1$454
This KAYAK deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/126:01 amMIA - VVI
1 stop16h 19mCopa Airlines
Mon 4/2112:17 pmVVI - MIA
1 stop13h 21mCopa Airlines
Deal found 4/1$469
This Trip.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/81:32 pmMIA - VVI
2 stops15h 03mLATAM Airlines
Mon 5/195:20 amVVI - MIA
1 stop9h 55mLATAM Airlines
Deal found 3/31$495
This Booking.com deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/510:00 pmMIA - VVI
Nonstop6h 50mBoA
Mon 9/811:35 pmVVI - MIA
Nonstop6h 50mBoA
Deal found 4/1$560
This Kiwi.com deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/305:19 pmMIA - VVI
1 stop10h 15mMultiple Airlines
Mon 6/232:55 amVVI - MIA
1 stop9h 35mMultiple Airlines
Deal found 4/1$566
This United Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/238:50 amMIA - VVI
2 stops37h 30mUnited Airlines
Sat 5/241:09 amVVI - MIA
2 stops21h 36mUnited Airlines
Deal found 4/1$601

Cheapflights Fare Finder

Customize your flight search to find flights from Key Largo to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 2, 2025.
Use the filters below to find and compare flights from Key Largo to Santa Cruz de la Sierra that are best for you.

Fly from

Key Largo

Fly to

Santa Cruz de la Sierra

Route

Depart

Return

Price

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

Mon 6/9

5:00 pm-1:50 am

1 stop8h 50m

Santa Cruz de la Sierra Viru Viru Intl

Sun 7/6

2:55 am-12:30 pm

1 stop9h 35m

$454

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

Sat 4/12

6:01 am-10:20 pm

1 stop16h 19m

Santa Cruz de la Sierra Viru Viru Intl

Mon 4/21

12:17 pm-1:38 am

1 stop13h 21m

$469

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

Thu 5/8

1:32 pm-4:35 am

2 stops15h 03m

Santa Cruz de la Sierra Viru Viru Intl

Mon 5/19

5:20 am-3:15 pm

1 stop9h 55m

$495

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

Fri 9/5

10:00 pm-4:50 am

Nonstop6h 50m

Santa Cruz de la Sierra Viru Viru Intl

Mon 9/8

11:35 pm-6:25 am

Nonstop6h 50m

$560

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

Fri 5/30

5:19 pm-3:34 am

1 stop10h 15m

Santa Cruz de la Sierra Viru Viru Intl

Mon 6/23

2:55 am-12:30 pm

1 stop9h 35m

$566

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

Wed 4/23

8:50 am-10:20 pm

2 stops37h 30m

Santa Cruz de la Sierra Viru Viru Intl

Sat 5/24

1:09 am-10:45 pm

2 stops21h 36m

$601

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

Sat 4/12

11:20 am-1:50 am

1 stop14h 30m

$209

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

Wed 6/4

6:27 pm-10:13 pm

1 stop27h 46m

$248

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

Tue 5/6

9:00 pm-5:20 am

Nonstop8h 20m

$249

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

Mon 5/12

9:00 am-10:13 pm

2 stops37h 13m

$270

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/1

Showing 1-10 of 12 results
1
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Best time to book a flight from Key Largo to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Key Largo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Key Largo to Santa Cruz de la Sierra

How far ahead should I book a flight from Key Largo to Santa Cruz de la Sierra?

Use this chart to determine the optimal time to book a round-trip flight from Key Largo to Santa Cruz de la Sierra. Price data was last updated on March 28, 2025.

Booking 85 days in advance of your planned departure date is, on average, the best time to get cheap flights from Key Largo to Santa Cruz de la Sierra. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Key Largo to Santa Cruz de la Sierra?

Currently, October is the cheapest month in which you can book a flight from Key Largo to Santa Cruz de la Sierra (average of $597). Flying from Key Largo to Santa Cruz de la Sierra in December is currently the most expensive (average of $822). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from KE9 to VVI?

Find hourly flight availability from Key Largo to Santa Cruz de la Sierra. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 2, 2025.

When flying from Key Largo to Santa Cruz de la Sierra, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What is the cheapest day to fly from Key Largo to Santa Cruz de la Sierra?

Use this chart to determine the cheapest time to fly round-trip from Key Largo to Santa Cruz de la Sierra. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Key Largo to Santa Cruz de la Sierra flight should consider departing on Sunday at noon when fares are most often at their lowest. Tuesday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Santa Cruz de la Sierra

Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated April 2, 2025.
Peruse reviews from past customers who have flown with Copa Airlines, LATAM Airlines and United Airlines from Key Largo to Santa Cruz de la Sierra to help guide your decision. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,400 reviews

Boarding

7.8

Entertainment

6.8

Crew

8.1

Overall

7.6

Food

6.8

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Anonymous,Mar 2025

PTY - JFK

There was no chance for me to choose a seat even if I were willing to pay extra for it when I was doing the check-in on line. My seats were the last row on the plane and they didn't have enough food to give me. I had to eat what was left after everybody else had their choice of food. This is unacceptable. Everyone should have a choice. I paid money just like everybody else. Never had this happened on any other airlines even if my seats were last row on the plane.
Copa Airlines
7.6
Good
1,400 reviews
Copa Airlines
7.6
Good
1,400 reviews

Boarding

7.8

Entertainment

6.8

Crew

8.1

Overall

7.6

Food

6.8

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Anonymous,Mar 2025

PTY - JFK

There was no chance for me to choose a seat even if I were willing to pay extra for it when I was doing the check-in on line. My seats were the last row on the plane and they didn't have enough food to give me. I had to eat what was left after everybody else had their choice of food. This is unacceptable. Everyone should have a choice. I paid money just like everybody else. Never had this happened on any other airlines even if my seats were last row on the plane.
LATAM Airlines
7.5
Good
1,754 reviews
Copa Airlines
7.6
Good
1,400 reviews

Boarding

7.8

Entertainment

6.8

Crew

8.1

Overall

7.6

Food

6.8

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Anonymous,Mar 2025

PTY - JFK

There was no chance for me to choose a seat even if I were willing to pay extra for it when I was doing the check-in on line. My seats were the last row on the plane and they didn't have enough food to give me. I had to eat what was left after everybody else had their choice of food. This is unacceptable. Everyone should have a choice. I paid money just like everybody else. Never had this happened on any other airlines even if my seats were last row on the plane.
United Airlines
7.4
Good
8,616 reviews
Copa Airlines
7.6
Good
1,400 reviews

Boarding

7.8

Entertainment

6.8

Crew

8.1

Overall

7.6

Food

6.8

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Anonymous,Mar 2025

PTY - JFK

There was no chance for me to choose a seat even if I were willing to pay extra for it when I was doing the check-in on line. My seats were the last row on the plane and they didn't have enough food to give me. I had to eat what was left after everybody else had their choice of food. This is unacceptable. Everyone should have a choice. I paid money just like everybody else. Never had this happened on any other airlines even if my seats were last row on the plane.
BoA
6.7
Okay
133 reviews
Copa Airlines
7.6
Good
1,400 reviews

Boarding

7.8

Entertainment

6.8

Crew

8.1

Overall

7.6

Food

6.8

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Anonymous,Mar 2025

PTY - JFK

There was no chance for me to choose a seat even if I were willing to pay extra for it when I was doing the check-in on line. My seats were the last row on the plane and they didn't have enough food to give me. I had to eat what was left after everybody else had their choice of food. This is unacceptable. Everyone should have a choice. I paid money just like everybody else. Never had this happened on any other airlines even if my seats were last row on the plane.
Avianca
6.7
Okay
2,302 reviews
Copa Airlines
7.6
Good
1,400 reviews

Boarding

7.8

Entertainment

6.8

Crew

8.1

Overall

7.6

Food

6.8

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Anonymous,Mar 2025

PTY - JFK

There was no chance for me to choose a seat even if I were willing to pay extra for it when I was doing the check-in on line. My seats were the last row on the plane and they didn't have enough food to give me. I had to eat what was left after everybody else had their choice of food. This is unacceptable. Everyone should have a choice. I paid money just like everybody else. Never had this happened on any other airlines even if my seats were last row on the plane.

Related info for your journey

Find useful and relevant information for your journey from Key Largo to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santa Cruz de la Sierra from Key Largo?

    For a flight from Key Largo to Santa Cruz de la Sierra, you will be flying into Viru Viru Intl. Santa Cruz de la Sierra Viru Viru Intl (VVI) is just 11.5 mi from the center of the city. Viru Viru Intl is the only Santa Cruz de la Sierra airport and it handles 0 inbound flights from Key Largo per day. 4 airlines have flights to Santa Cruz de la Sierra Viru Viru Intl from Key Largo on a regular basis.

  • How popular is this Key Largo to Santa Cruz de la Sierra flight route?

    Flights from Key Largo to Santa Cruz de la Sierra Viru Viru Intl have been viewed 21 times in the past calendar month.

  • What are the cheapest airlines to fly from Key Largo to Santa Cruz de la Sierra one-way?

    To fly one-way, consider booking your trip with Avianca, which is currently one of the cheapest options available, starting at $209. Copa Airlines flights start at $248 while deals on BoA start at $249 one-way.

  • What are the cheapest flights from Key Largo to Santa Cruz de la Sierra?

    Looking at all options, your cheapest flight can be booked for $262. While the most popular route (Miami - Santa Cruz de la Sierra Viru Viru Intl) can be booked for $468 on average our data indicates $893 when flying from Key Largo to Santa Cruz de la Sierra.

  • Can I find deals for flights from Key Largo to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on Key Largo to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Key Largo to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key Largo to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from Key Largo to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from Key Largo to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Key Largo to Santa Cruz de la Sierra?

    Currently, October is the cheapest month in which you can book a flight from Key Largo to Santa Cruz de la Sierra (average of $597). Flying from Key Largo to Santa Cruz de la Sierra in December is currently the most expensive (average of $822). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Key Largo to Santa Cruz de la Sierra

Discover the top 4 airlines that operate flights from Key Largo to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 2, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$376Average$558FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$379Average$547FlexibilityNo cancel feeOn-time70%
LATAM AirlinesCheapest$524Average$613FlexibilityNo cancel feeOn-time81%
BoACheapest$535Average$690FlexibilityNo cancel feeOn-timeN/A

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