HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Santa Cruz de la Sierra

$507+ Cheap flights from Indiana to Santa Cruz de la Sierra (VVI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/19. Fares are subject to change and may not be available on all flights or dates of travel.
IND — VVI
Feb 25 — Mar 41
Tue 2/25
Tue 3/4
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Indiana to Santa Cruz de la Sierra with Cheapflights

1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”
2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.
3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Indiana to Santa Cruz de la Sierra

Keep the following information in mind while searching for Indiana to Santa Cruz de la Sierra flight deals. Data was last updated February 20, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
1 star

Round-trip from

$581
(United Airlines)

One-way from

$507
(United)
Provider with most accurate pricing for Indianapolis-Santa Cruz de la Sierra Viru Viru Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Indianapolis-Santa Cruz de la Sierra Viru Viru Intl flights.
Search Deals
From Indiana to Santa Cruz de la Sierra Viru Viru Intl
Search Deals
One-way flight from Indiana to Santa Cruz de la Sierra Viru Viru Intl
Search Deals

Find flight deals from Indiana to Santa Cruz de la Sierra

Cheapest flights from Indiana to Santa Cruz de la Sierra
Explore the most affordable flight options available from Indiana to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/67:55 pmORD - VVI
2 stops25h 25mUnited Airlines
Sat 4/121:15 amVVI - ORD
2 stops33h 56mUnited Airlines
Deal found 2/20$581
This Booking.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/293:09 pmORD - VVI
1 stop30h 08mCopa Airlines
Mon 4/1412:17 pmVVI - ORD
1 stop26h 25mCopa Airlines
Deal found 2/20$599
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/297:45 pmORD - VVI
3 stops29h 05mMultiple Airlines
Mon 4/1412:17 pmVVI - ORD
2 stops30h 43mMultiple Airlines
Deal found 2/20$743
This United deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/316:45 amIND - VVI
2 stops14h 59mUnited Airlines
Tue 11/1112:55 amVVI - IND
2 stops17h 52mUnited Airlines
Deal found 2/19$757
This Trip.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/293:05 pmORD - VVI
1 stop33h 45mAvianca
Sun 4/132:55 amVVI - ORD
1 stop11h 20mAvianca
Deal found 2/20$845
This Gurufare deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/256:25 pmIND - VVI
2 stops34h 10mLATAM Airlines
Wed 7/308:26 amVVI - IND
2 stops32h 52mLATAM Airlines
Deal found 2/19$1,320
This Gurufare deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/152:50 pmORD - VVI
2 stops19h 45mGOL
Sun 3/2312:35 pmVVI - ORD
2 stops28h 30mGOL
Deal found 2/19$1,711
This Justfly.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/205:45 amORD - VVI
2 stops46h 00mLATAM Airlines
Sun 3/3010:16 amVVI - ORD
2 stops32h 27mLATAM Airlines
Deal found 2/20$1,728
This Copa Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/259:00 amIND - VVI
2 stops18h 34mCopa Airlines
Thu 6/2612:15 pmVVI - IND
2 stops21h 50mCopa Airlines
Deal found 2/19$2,001

Find flights from Indiana to Santa Cruz de la Sierra within your budget

Customize your flight search to find flights from Indiana to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.

Fly from

Indiana

Fly to

Santa Cruz de la Sierra

Route

Depart

Return

Price

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Sun 4/6

7:55 pm-10:20 pm

2 stops25h 25m

Santa Cruz de la Sierra Viru Viru Intl

Sat 4/12

1:15 am-10:11 am

2 stops33h 56m

$581

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Sat 3/29

3:09 pm-10:17 pm

1 stop30h 08m

Santa Cruz de la Sierra Viru Viru Intl

Mon 4/14

12:17 pm-1:42 pm

1 stop26h 25m

$599

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Sat 3/29

7:45 pm-1:50 am

3 stops29h 05m

Santa Cruz de la Sierra Viru Viru Intl

Mon 4/14

12:17 pm-6:00 pm

2 stops30h 43m

$743

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Sat 3/29

3:05 pm-1:50 am

1 stop33h 45m

Santa Cruz de la Sierra Viru Viru Intl

Sun 4/13

2:55 am-1:15 pm

1 stop11h 20m

$845

IndianapolisSanta Cruz de la Sierra

IND - VVI

INDVVI

Indianapolis

Thu 5/1

7:00 am-10:13 pm

2 stops15h 13m

Santa Cruz de la Sierra Viru Viru Intl

Wed 5/7

1:09 am-8:11 pm

2 stops19h 02m

$884

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Sat 3/15

2:50 pm-11:35 am

2 stops19h 45m

Santa Cruz de la Sierra Viru Viru Intl

Sun 3/23

12:35 pm-4:05 pm

2 stops28h 30m

$1,711

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Thu 3/20

5:45 am-4:45 am

2 stops46h 00m

Santa Cruz de la Sierra Viru Viru Intl

Sun 3/30

10:16 am-5:43 pm

2 stops32h 27m

$1,728

IndianapolisSanta Cruz de la Sierra

IND - VVI

INDVVI

Indianapolis

Fri 2/28

2:00 pm-4:45 am

2 stops37h 45m

Santa Cruz de la Sierra Viru Viru Intl

Sun 3/16

11:11 am-4:14 pm

2 stops29h 03m

$1,872

IndianapolisSanta Cruz de la Sierra

IND - VVI

INDVVI

Indianapolis

Fri 2/28

7:20 pm-10:04 pm

2 stops25h 44m

Santa Cruz de la Sierra Viru Viru Intl

Sat 3/15

12:51 am-7:18 pm

2 stops18h 27m

$2,905

IndianapolisSanta Cruz de la Sierra

IND - VVI

INDVVI

Indianapolis

Mon 5/19

4:57 pm-10:13 pm

2 stops53h 16m

$507

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/19

Best time to book a flight from Indiana to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Indiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Indiana to Santa Cruz de la Sierra

Get recent, data-driven insights about flights from Indiana to Santa Cruz de la Sierra including ideal travel times, pricing trends, and more.
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Santa Cruz de la Sierra

Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated February 20, 2025.
To help decide which airline to fly from Indiana to Santa Cruz de la Sierra, see what other customers have to say about Copa Airlines, LATAM Airlines and United Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,510 reviews

Boarding

7.8

Entertainment

6.9

Comfort

7.4

Crew

8.1

Food

6.9

Overall

7.6

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

Copa Airlines
7.6
Good
1,510 reviews
Copa Airlines
7.6
Good
1,510 reviews

Boarding

7.8

Entertainment

6.9

Comfort

7.4

Crew

8.1

Food

6.9

Overall

7.6

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

LATAM Airlines
7.5
Good
1,795 reviews
Copa Airlines
7.6
Good
1,510 reviews

Boarding

7.8

Entertainment

6.9

Comfort

7.4

Crew

8.1

Food

6.9

Overall

7.6

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

United Airlines
7.4
Good
8,765 reviews
Copa Airlines
7.6
Good
1,510 reviews

Boarding

7.8

Entertainment

6.9

Comfort

7.4

Crew

8.1

Food

6.9

Overall

7.6

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

GOL
7.3
Good
1,065 reviews
Copa Airlines
7.6
Good
1,510 reviews

Boarding

7.8

Entertainment

6.9

Comfort

7.4

Crew

8.1

Food

6.9

Overall

7.6

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

Avianca
6.8
Okay
2,435 reviews
Copa Airlines
7.6
Good
1,510 reviews

Boarding

7.8

Entertainment

6.9

Comfort

7.4

Crew

8.1

Food

6.9

Overall

7.6

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

Related info for your journey

Find useful and relevant information for your journey from Indiana to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santa Cruz de la Sierra from Indiana?

    For a flight from Indiana to Santa Cruz de la Sierra, you will be flying into Viru Viru Intl. Santa Cruz de la Sierra Viru Viru Intl (VVI) is just 11.5 mi from the center of the city.

  • What are the most popular routes from Indiana to Santa Cruz de la Sierra?

    Most travelers choose Chicago O'Hare Intl - Santa Cruz de la Sierra Viru Viru Intl, Indianapolis - Santa Cruz de la Sierra Viru Viru Intl or Cincinnati Cinci./N. Kentucky - Santa Cruz de la Sierra Viru Viru Intl when deciding on the best route from Indiana to Santa Cruz de la Sierra.

  • Can I find deals for flights from Indiana to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on Indiana to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indiana to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indiana to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from Indiana to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from Indiana to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indiana to Santa Cruz de la Sierra?

    Currently, October is the cheapest month in which you can book a flight from Indiana to Santa Cruz de la Sierra (average of $597). Flying from Indiana to Santa Cruz de la Sierra in December is currently the most expensive (average of $822). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Indiana to Santa Cruz de la Sierra

See prices for flight routes from nearby airports that may be better suited for you.
Miami to Santa Cruz de la Sierra flights
Dulles Intl to Santa Cruz de la Sierra flights
Reagan-National to Santa Cruz de la Sierra flights
John F Kennedy Intl to Santa Cruz de la Sierra flights
Miami to Cochabamba flights
Baltimore to Santa Cruz de la Sierra flights
Los Angeles to La Paz flights
Newark to Santa Cruz de la Sierra flights
John F Kennedy Intl to La Paz flights
Dulles Intl to La Paz flights
LaGuardia to Santa Cruz de la Sierra flights
Los Angeles to Santa Cruz de la Sierra flights
Reagan-National to La Paz flights
Miami to La Paz flights
Dulles Intl to Cochabamba flights
LaGuardia to La Paz flights
O'Hare Intl to La Paz flights
Boston to La Paz flights
Newark to La Paz flights
Denver to Santa Cruz de la Sierra flights
Boston to Santa Cruz de la Sierra flights
Baltimore to La Paz flights
O'Hare Intl to Santa Cruz de la Sierra flights
San Francisco to La Paz flights
Atlanta to La Paz flights
Reagan-National to Cochabamba flights
Fort Lauderdale to La Paz flights
John F Kennedy Intl to Trinidad flights
Hobby to Santa Cruz de la Sierra flights
George Bush Intcntl to Santa Cruz de la Sierra flights
Dallas/Fort Worth to Santa Cruz de la Sierra flights
Seattle to La Paz flights
Denver to La Paz flights
Dallas/Fort Worth to La Paz flights
Seattle to Santa Cruz de la Sierra flights
San Francisco to Santa Cruz de la Sierra flights
Atlanta to Santa Cruz de la Sierra flights
Fort Lauderdale to Santa Cruz de la Sierra flights
Hobby to La Paz flights
Orlando to La Paz flights
Orlando to Santa Cruz de la Sierra flights
Nashville to Santa Cruz de la Sierra flights
Sky Harbor Intl to La Paz flights
Love Field to La Paz flights
George Bush Intcntl to La Paz flights
Raleigh to La Paz flights
Baltimore to Cochabamba flights
Ontario to La Paz flights

Top airline flying from Indiana to Santa Cruz de la Sierra

Discover the top airline that operate flights from Indiana to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$614Average$889FlexibilityNo cancel feeOn-time69%
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.