Santa Cruz de la Sierra

$266+ Cheap flights from Denver (DEN) to Santa Cruz de la Sierra (VVI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/5. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — VVI
Feb 27 — Mar 61
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Denver to Santa Cruz de la Sierra with Cheapflights

1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”
2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.
3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Denver to Santa Cruz de la Sierra

Discover tips and strategies to find the most affordable flight options for your journey from Denver (DEN) to Santa Cruz de la Sierra (VVI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 22, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$581
(United)

One-way from

$266
(Kiwi.com)

Popular in

December

Cheapest in

January

Average price

$659
Provider with most accurate pricing for Denver Intl-Santa Cruz de la Sierra Viru Viru Intl flight deals.
Provider most trusted by Cheapflights users for Denver Intl-Santa Cruz de la Sierra Viru Viru Intl flights.
From Denver Intl to Santa Cruz de la Sierra Viru Viru Intl
One-way flight from Denver Intl to Santa Cruz de la Sierra Viru Viru Intl
High demand for flights, 6% potential price rise
Cheapest flight prices on average. 4% potential price decrease ($35 potential savings vs. average RT price).
Average for round-trip flights in February 2025

Find flight deals from Denver to Santa Cruz de la Sierra

Cheapest flights from Denver to Santa Cruz de la Sierra
Explore the most affordable flight options available from Denver to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 22, 2025.

This United deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/15:20 amDEN - VVI
2 stops15h 00mUnited Airlines
Sat 4/191:15 amVVI - DEN
2 stops24h 29mUnited Airlines
Deal found 2/21$581
This United deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/225:20 pmDEN - VVI
2 stops30h 40mMultiple Airlines
Fri 3/2812:51 amVVI - DEN
2 stops34h 09mMultiple Airlines
Deal found 2/20$792
This KAYAK deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/1310:20 pmDEN - VVI
1 stop21h 53mCopa Airlines
Fri 7/41:09 amVVI - DEN
1 stop18h 54mCopa Airlines
Deal found 2/21$907
This Gurufare deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1811:53 amDEN - VVI
2 stops21h 12mGOL
Mon 5/2612:00 pmVVI - DEN
2 stops24h 05mGOL
Deal found 2/21$1,470
This FlightHub deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1812:59 amDEN - VVI
2 stops52h 43mLATAM Airlines
Tue 5/275:20 amVVI - DEN
2 stops30h 08mLATAM Airlines
Deal found 2/21$1,500

Find flights from Denver to Santa Cruz de la Sierra within your budget

Customize your flight search to find flights from Denver to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 22, 2025.

Fly from

Denver

Fly to

Santa Cruz de la Sierra

Route

Depart

Return

Price

DenverSanta Cruz de la Sierra

DEN - VVI

DENVVI

Denver Intl

Tue 4/1

5:20 am-10:20 pm

2 stops15h 00m

Santa Cruz de la Sierra Viru Viru Intl

Sat 4/19

1:15 am-11:44 pm

2 stops24h 29m

$581

DenverSanta Cruz de la Sierra

DEN - VVI

DENVVI

Denver Intl

Sat 3/22

5:20 pm-2:00 am

2 stops30h 40m

Santa Cruz de la Sierra Viru Viru Intl

Fri 3/28

12:51 am-9:00 am

2 stops34h 09m

$792

DenverSanta Cruz de la Sierra

DEN - VVI

DENVVI

Denver Intl

Fri 6/13

10:20 pm-10:13 pm

1 stop21h 53m

Santa Cruz de la Sierra Viru Viru Intl

Fri 7/4

1:09 am-6:03 pm

1 stop18h 54m

$907

DenverSanta Cruz de la Sierra

DEN - VVI

DENVVI

Denver Intl

Sun 5/18

11:53 am-11:05 am

2 stops21h 12m

Santa Cruz de la Sierra Viru Viru Intl

Mon 5/26

12:00 pm-10:05 am

2 stops24h 05m

$1,470

DenverSanta Cruz de la Sierra

DEN - VVI

DENVVI

Denver Intl

Sun 5/18

12:59 am-7:42 am

2 stops52h 43m

Santa Cruz de la Sierra Viru Viru Intl

Tue 5/27

5:20 am-9:28 am

2 stops30h 08m

$1,500

DenverSanta Cruz de la Sierra

DEN - VVI

DENVVI

Denver Intl

Mon 5/5

11:45 am-1:50 am

3 stops36h 05m

$266

DenverSanta Cruz de la Sierra

DEN - VVI

DENVVI

Denver Intl

Mon 5/5

10:25 pm-10:13 pm

1 stop21h 48m

$673

DenverSanta Cruz de la Sierra

DEN - VVI

DENVVI

Denver Intl

Mon 5/5

10:25 pm-10:13 pm

1 stop21h 48m

$1,263

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/21

Compare providers for flights from Denver to Santa Cruz de la Sierra

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Denver to Santa Cruz de la Sierra in February.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Denver-Santa Cruz de la Sierra flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Denver-Santa Cruz de la Sierra flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Denver-Santa Cruz de la Sierra flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Denver-Santa Cruz de la Sierra flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Denver-Santa Cruz de la Sierra flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Denver to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Denver with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Santa Cruz de la Sierra

Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated February 22, 2025.

Comfort

7.4

Food

6.9

Crew

8.1

Entertainment

6.9

Boarding

7.8

Overall

7.6

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

Comfort

7.4

Food

6.9

Crew

8.1

Entertainment

6.9

Boarding

7.8

Overall

7.6

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

Comfort

7.4

Food

6.9

Crew

8.1

Entertainment

6.9

Boarding

7.8

Overall

7.6

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

Comfort

7.4

Food

6.9

Crew

8.1

Entertainment

6.9

Boarding

7.8

Overall

7.6

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

Comfort

7.4

Food

6.9

Crew

8.1

Entertainment

6.9

Boarding

7.8

Overall

7.6

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

Related info for your journey

Find useful and relevant information for your journey from Denver to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What are the cheapest airlines flying from Denver to Santa Cruz de la Sierra round-trip?

    Flying on United Airlines is currently your cheapest option to Santa Cruz de la Sierra, with prices starting at $581. Additional round-trip tickets that might be worth considering are offered by Copa Airlines and GOL, with the lowest prices starting at $1,464 and $1,470, respectively. United Airlines is priced at 30% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Denver to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on Denver to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Denver to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from Denver to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from Denver to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Denver to Santa Cruz de la Sierra?

    Currently, October is the cheapest month in which you can book a flight from Denver to Santa Cruz de la Sierra (average of $597). Flying from Denver to Santa Cruz de la Sierra in December is currently the most expensive (average of $822). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Denver to Santa Cruz de la Sierra

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Denver to Santa Cruz de la Sierra

Discover the top 2 airlines that operate flights from Denver to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 22, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$565Average$688FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$596Average$823FlexibilityNo cancel feeOn-time69%
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.