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$129+ Cheap flights from Medford to Santa Ana, CA (MFR - SNA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/28. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — SNA
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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1. Tell us where you want to go

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Cheapflights Tip: The best prices from Medford to Santa Ana J. Wayne/Orange Cnty are usually found in March or May, booked 67 days in advance, depart on a Saturday or Thursday and return on a Wednesday

Cheap flight deals from Medford to Santa Ana

Cheapest flights from Medford to Santa Ana
Explore the most affordable flight options available from Medford to Santa Ana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/219:56 pmMFR - SNA
1 stop21h 25mMultiple Airlines
Fri 1/24:12 pmSNA - MFR
Nonstop2h 08mMultiple Airlines
Deal found 12/11$287
This Delta deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:00 amMFR - SNA
1 stop6h 44mDelta
Thu 1/15:01 pmSNA - MFR
1 stop5h 52mDelta
Deal found 12/9$289
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/219:56 pmMFR - SNA
1 stop21h 25mMultiple Airlines
Sun 1/46:41 pmSNA - MFR
Nonstop2h 08mMultiple Airlines
Deal found 12/11$310
This Booking.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/214:07 pmMFR - SNA
Nonstop2h 01mAllegiant Air
Fri 1/24:12 pmSNA - MFR
Nonstop2h 08mAllegiant Air
Deal found 12/11$315
This Booking.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/214:07 pmMFR - SNA
Nonstop2h 01mAllegiant Air
Sun 1/46:41 pmSNA - MFR
Nonstop2h 08mAllegiant Air
Deal found 12/11$334
This Delta deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:00 amMFR - SNA
1 stop6h 44mDelta
Tue 12/307:15 pmSNA - MFR
1 stop4h 39mDelta
Deal found 12/9$349
This United Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/242:06 pmMFR - SNA
1 stop6h 36mUnited Airlines
Wed 12/317:05 pmSNA - MFR
1 stop3h 52mUnited Airlines
Deal found 12/9$359
This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/252:06 pmMFR - SNA
1 stop6h 36mUnited Airlines
Sun 1/47:05 pmSNA - MFR
1 stop3h 52mUnited Airlines
Deal found 12/11$367
This United Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/242:06 pmMFR - SNA
1 stop6h 36mUnited Airlines
Thu 1/13:59 pmSNA - MFR
1 stop6h 58mUnited Airlines
Deal found 12/9$389
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2512:39 pmMFR - SNA
1 stop4h 21mMultiple Airlines
Sun 1/46:41 pmSNA - MFR
Nonstop2h 08mMultiple Airlines
Deal found 12/11$403
This United Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/202:06 pmMFR - SNA
1 stop6h 36mUnited Airlines
Wed 12/317:05 pmSNA - MFR
1 stop3h 52mUnited Airlines
Deal found 12/9$409

Find flight deals from Medford to Santa Ana

Discover tips and strategies to find the most affordable flight options for your journey from Medford (MFR) to Santa Ana (SNA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$140
(Booking.com)

One-way from

$129
(Alaska Airlines)

Popular in

September

Cheapest in

March

Average price

$329

Good round-trip deal

$184 or less

Good one-way deal

$156 or less
Provider with most accurate pricing for Medford-Santa Ana J. Wayne/Orange Cnty flight deals.
Search Deals
Provider most trusted by Cheapflights users for Medford-Santa Ana J. Wayne/Orange Cnty flights.
Search Deals
From Medford to Santa Ana J. Wayne/Orange Cnty
Search Deals
One-way flight from Medford to Santa Ana J. Wayne/Orange Cnty
Search Deals
Highest demand for flights based on searches. 21% potential increase in price ($69 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals
Price to beat on a round-trip flight from Medford to Santa Ana J. Wayne/Orange Cnty.
Search Deals
Price to beat on a one-way flight from Medford to Santa Ana J. Wayne/Orange Cnty.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Medford to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Medford to Santa Ana that are best for you.

Fly from

Medford

Fly to

Santa Ana

Route

Depart

Return

Price

MedfordSanta Ana

MFR - SNA

MFRSNA

Medford

Fri 1/2

1:26 pm-3:27 pm

Nonstop2h 01m

Santa Ana J. Wayne/Orange Cnty

Thu 1/8

6:23 pm-8:31 pm

Nonstop2h 08m

$140

MedfordSanta Ana

MFR - SNA

MFRSNA

Medford

Fri 1/2

1:26 pm-3:27 pm

Nonstop2h 01m

Santa Ana J. Wayne/Orange Cnty

Thu 1/15

6:23 pm-8:31 pm

Nonstop2h 08m

$154

MedfordSanta Ana

MFR - SNA

MFRSNA

Medford

Wed 1/7

5:20 pm-10:18 pm

1 stop4h 58m

Santa Ana J. Wayne/Orange Cnty

Wed 1/14

3:30 pm-10:59 pm

1 stop7h 29m

$187

MedfordSanta Ana

MFR - SNA

MFRSNA

Medford

Wed 1/7

1:22 pm-6:38 pm

1 stop5h 16m

Santa Ana J. Wayne/Orange Cnty

Wed 1/14

10:14 am-11:56 pm

1 stop13h 42m

$187

MedfordSanta Ana

MFR - SNA

MFRSNA

Medford

Fri 1/30

5:20 pm-10:18 pm

1 stop4h 58m

Santa Ana J. Wayne/Orange Cnty

Sun 2/1

11:15 am-4:40 pm

1 stop5h 25m

$187

MedfordSanta Ana

MFR - SNA

MFRSNA

Medford

Thu 1/15

9:21 pm-8:57 pm

1 stop23h 36m

Santa Ana J. Wayne/Orange Cnty

Sun 1/18

6:23 pm-8:31 pm

Nonstop2h 08m

$216

MedfordSanta Ana

MFR - SNA

MFRSNA

Medford

Thu 2/26

11:30 am-4:14 pm

1 stop4h 44m

Santa Ana J. Wayne/Orange Cnty

Sun 3/1

8:30 am-4:40 pm

1 stop8h 10m

$236

MedfordSanta Ana

MFR - SNA

MFRSNA

Medford

Fri 1/23

5:42 am-4:12 pm

1 stop10h 30m

Santa Ana J. Wayne/Orange Cnty

Mon 1/26

6:45 am-4:08 pm

2 stops9h 23m

$255

MedfordSanta Ana

MFR - SNA

MFRSNA

Medford

Thu 1/15

5:42 am-4:12 pm

1 stop10h 30m

Santa Ana J. Wayne/Orange Cnty

Sun 1/18

7:45 am-11:56 pm

1 stop16h 11m

$256

MedfordSanta Ana

MFR - SNA

MFRSNA

Medford

Sun 2/22

11:25 am-1:30 pm

Nonstop2h 05m

Santa Ana J. Wayne/Orange Cnty

Fri 2/27

6:45 am-12:01 pm

1 stop5h 16m

$260

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Showing 1-10 of 18 results
1
2

Compare providers for flights from Medford to Santa Ana

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Medford to Santa Ana in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Medford-Santa Ana, California flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Medford-Santa Ana, California flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Medford-Santa Ana, California flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Medford-Santa Ana, California flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Medford-Santa Ana, California flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Medford to Santa Ana

Have a flexible travel schedule? Discover the best time to fly to Santa Ana from Medford with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Medford to Santa Ana

How far ahead should I book a flight from Medford to Santa Ana, California?

Use this chart to determine the optimal time to book a round-trip flight from Medford to Santa Ana. Price data was last updated on December 5, 2025.

To ensure you get the cheapest price possible for a flight from Medford to Santa Ana, California, you should look to book at least 67 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Medford to Santa Ana, California?

Currently, July is the cheapest month in which you can book a flight from Medford to Santa Ana, California (average of $61). Flying from Medford to Santa Ana, California in December is currently the most expensive (average of $177). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MFR to SNA?

Find hourly flight availability from Medford to Santa Ana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

A simple way to save on the total cost of your ticket is to fly from Medford to Santa Ana, California in the afternoon. If you’re flexible enough to do this you can expect to save up to 56% on your trip compared to booking a flight in the evening.

Reviews of airlines servicing Santa Ana

Get insights into the airlines that provide service to Santa Ana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Ana. Reviews last updated December 12, 2025.
See what other customers who have flown with Alaska Airlines, Delta, and United Airlines from Medford to Santa Ana have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
11,432 reviews

Boarding

8.1

Overall

8.0

Comfort

7.8

Crew

8.5

Food

7.1

Entertainment

7.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Alaska Airlines
8.0
Very good
11,432 reviews
Alaska Airlines
8.0
Very good
11,432 reviews

Boarding

8.1

Overall

8.0

Comfort

7.8

Crew

8.5

Food

7.1

Entertainment

7.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Delta
7.9
Good
8,007 reviews
Alaska Airlines
8.0
Very good
11,432 reviews

Boarding

8.1

Overall

8.0

Comfort

7.8

Crew

8.5

Food

7.1

Entertainment

7.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
United Airlines
7.4
Good
9,095 reviews
Alaska Airlines
8.0
Very good
11,432 reviews

Boarding

8.1

Overall

8.0

Comfort

7.8

Crew

8.5

Food

7.1

Entertainment

7.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Allegiant Air
7.2
Good
699 reviews
Alaska Airlines
8.0
Very good
11,432 reviews

Boarding

8.1

Overall

8.0

Comfort

7.8

Crew

8.5

Food

7.1

Entertainment

7.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.

Related info for your journey

Find useful and relevant information for your journey from Medford to Santa Ana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Medford to Santa Ana, California flight route?

    Within the past month, 1 users have taken a look at flights from Medford to Santa Ana J. Wayne/Orange Cnty.

  • How long is the flight from Medford to Santa Ana, California?

    Departing from Medford to Santa Ana, California will take you 2h 01m. Airlines will cover a distance of 659 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Medford to Santa Ana, California round-trip?

    Our cheapest airline available from Medford to Santa Ana, California is Allegiant Air. Our recent data shows that you can find tickets from as low as $85 on this airline. Additional options worth looking into are Delta and United Airlines, starting at $163 and $232 round-trip. You may be able to fly from Medford to Santa Ana, California for 65% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Medford to Santa Ana, California one-way?

    The cheapest airlines for a one-way flight from Medford to Santa Ana, California are Allegiant Air ($66), Alaska Airlines ($109), and Delta ($109).

  • What are the cheapest flights from Medford to Santa Ana, California?

    Looking at all options, your cheapest flight can be booked for $97. While the most popular route (Medford - Santa Ana J. Wayne/Orange Cnty) can be booked for $154 on average, our data indicates $182 when flying from Medford to Santa Ana, California.

  • Can I find deals for flights from Medford to Santa Ana that include hotel bookings?

    Yes. In addition to deals on Medford to Santa Ana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Medford to Santa Ana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to Santa Ana.

  • Can I find deals for business class flights from Medford to Santa Ana?

    Yes. Cheapflights offers flight deals from Medford to Santa Ana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Medford to Santa Ana, California?

    Currently, July is the cheapest month in which you can book a flight from Medford to Santa Ana, California (average of $61). Flying from Medford to Santa Ana, California in December is currently the most expensive (average of $177). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santa Ana?

Book flights to Santa Ana if you plan to visit one of these locations
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Alternative routes for Medford to Santa Ana

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Medford to Santa Ana

Discover the top 4 airlines that operate flights from Medford to Santa Ana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$90Average$165FlexibilityNo cancel feeOn-time88%
DeltaCheapest$183Average$374FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$232Average$389FlexibilityNo cancel feeOn-time69%
Alaska AirlinesCheapest$257Average$382FlexibilityNo cancel feeOn-time75%

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