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$82+ Cheap flights from South Carolina to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/13. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — SFO
ene. 14 — ene. 211
mié. 1/14
mié. 1/21
1 adult, Economy
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Cheap flight deals from South Carolina to San Francisco

Cheapest flights from South Carolina to San Francisco
Explore the most affordable flight options available from South Carolina to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 15, 2025.

This Trip.com deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/245:14 pmCLT - SFO
1 stop18h 09mFrontier
jue. 1/85:44 pmSFO - CLT
2 stops12h 18mFrontier
Deal found 12/13$378
This Priceline deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/245:14 pmCLT - SFO
1 stop10h 10mFrontier
sáb. 1/36:24 amSFO - CLT
1 stop9h 13mFrontier
Deal found 12/13$383
This Frontier deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/2010:22 pmCLT - SFO
1 stop15h 25mFrontier
mié. 12/316:24 amSFO - CLT
1 stop6h 55mFrontier
Deal found 12/13$387
This Kiwi.com deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/232:22 pmCLT - SFO
2 stops57h 08mFrontier
mié. 12/316:24 amSFO - CLT
1 stop25h 58mFrontier
Deal found 12/12$414
This Kiwi.com deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/209:34 pmCLT - SFO
2 stops16h 13mMultiple Airlines
mié. 12/316:24 amSFO - CLT
1 stop25h 58mMultiple Airlines
Deal found 12/13$418
This Kiwi.com deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/249:34 pmCLT - SFO
2 stops27h 02mMultiple Airlines
mié. 12/316:24 amSFO - CLT
1 stop25h 58mMultiple Airlines
Deal found 12/12$420
This Kiwi.com deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/315:14 pmCLT - SFO
1 stop10h 10mMultiple Airlines
jue. 1/85:44 pmSFO - CLT
2 stops13h 33mMultiple Airlines
Deal found 12/12$422
This Kiwi.com deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/315:14 pmCLT - SFO
1 stop10h 10mFrontier
jue. 1/85:44 pmSFO - CLT
2 stops23h 07mFrontier
Deal found 12/12$430
This Southwest deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/246:10 amCLT - SFO
1 stop7h 50mSouthwest
jue. 1/86:05 amSFO - CLT
1 stop9h 25mSouthwest
Deal found 12/13$436
This Frontier deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/245:14 pmCLT - SFO
1 stop10h 10mFrontier
mié. 12/316:24 amSFO - CLT
1 stop6h 55mFrontier
Deal found 12/12$437
This Southwest deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/2512:55 pmCLT - SFO
2 stops12h 35mSouthwest
jue. 1/89:30 pmSFO - CLT
1 stop9h 50mSouthwest
Deal found 12/13$441
This eDestinos deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/199:04 pmCLT - SFO
2 stops28h 50mMultiple Airlines
mar. 1/67:00 amSFO - CLT
2 stops29h 37mMultiple Airlines
Deal found 12/13$443

Find flight deals from South Carolina to San Francisco

Keep the following information in mind while searching for South Carolina to San Francisco flight deals. Data was last updated diciembre 15, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$251
(United Airlines)

One-way from

$82
(Trip.com)

Popular in

February

Cheapest in

April

Average price

$542
Provider with most accurate pricing for Myrtle Beach Intl-San Francisco flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-San Francisco flights.
Search Deals
From South Carolina to San Francisco
Search Deals
One-way flight from South Carolina to San Francisco
Search Deals
Highest demand for flights based on searches. 27% potential increase in price ($201 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 13% potential price decrease ($66 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 15, 2025.
Use the filters below to find and compare flights from South Carolina to San Francisco that are best for you.

Fly from

South Carolina

Fly to

San Francisco

Route

Depart

Return

Price

CharlestonSan Francisco

CHS - SFO

CHSSFO

Charleston

mié. 1/21

6:00 am-12:15 pm

1 stop9h 15m

San Francisco

mié. 1/21

11:15 pm-12:32 pm

1 stop10h 17m

$251

CharlestonSan Francisco

CHS - SFO

CHSSFO

Charleston

mar. 1/27

1:13 pm-7:09 pm

1 stop8h 56m

San Francisco

mar. 2/3

10:35 am-11:44 pm

1 stop10h 09m

$251

CharlestonSan Francisco

CHS - SFO

CHSSFO

Charleston

mar. 2/24

6:32 pm-10:37 am

1 stop19h 05m

San Francisco

vie. 2/27

6:30 am-5:32 pm

1 stop8h 02m

$256

CharlestonSan Francisco

CHS - SFO

CHSSFO

Charleston

jue. 2/19

6:00 am-1:38 pm

1 stop10h 38m

San Francisco

sáb. 2/21

11:20 pm-10:09 am

1 stop7h 49m

$257

CharlestonSan Francisco

CHS - SFO

CHSSFO

Charleston

vie. 1/9

7:22 pm-8:11 am

1 stop15h 49m

San Francisco

dom. 1/11

6:00 am-6:22 pm

1 stop9h 22m

$262

CharlestonSan Francisco

CHS - SFO

CHSSFO

Charleston

vie. 1/23

7:22 pm-8:11 am

1 stop15h 49m

San Francisco

dom. 1/25

7:00 am-6:22 pm

1 stop8h 22m

$262

CharlestonSan Francisco

CHS - SFO

CHSSFO

Charleston

vie. 1/9

12:09 pm-10:32 pm

1 stop13h 23m

San Francisco

lun. 1/12

8:29 pm-11:13 am

1 stop11h 44m

$263

CharlestonSan Francisco

CHS - SFO

CHSSFO

Charleston

jue. 1/22

6:05 am-12:10 pm

1 stop9h 05m

San Francisco

lun. 1/26

11:56 pm-12:32 pm

1 stop9h 36m

$263

CharlestonSan Francisco

CHS - SFO

CHSSFO

Charleston

vie. 1/16

7:45 pm-1:30 am

1 stop8h 45m

San Francisco

lun. 1/19

11:56 pm-12:32 pm

1 stop9h 36m

$263

CharlestonSan Francisco

CHS - SFO

CHSSFO

Charleston

jue. 1/22

5:13 pm-10:59 pm

1 stop8h 46m

San Francisco

dom. 1/25

11:56 pm-12:32 pm

1 stop9h 36m

$263

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/14

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to San Francisco

What is the cheapest month to book a flight from South Carolina to San Francisco?

Currently, November is the cheapest month in which you can book a flight from South Carolina to San Francisco (average of $160). Flying from South Carolina to San Francisco in March is currently the most expensive (average of $271). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to SFO?

Find hourly flight availability from South Carolina to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated diciembre 15, 2025.

A simple way to save on the total cost of your ticket is to fly from South Carolina to San Francisco in the afternoon. If you’re flexible enough to do this you can expect to save up to 7% on your trip compared to booking a flight in the morning.

What is the cheapest day to fly from South Carolina to San Francisco?

Use this chart to determine the cheapest time to fly round-trip from South Carolina to San Francisco. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their South Carolina to San Francisco flight should consider departing on Tuesday mornings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from South Carolina to San Francisco

Explore weekly flight availability from South Carolina to San Francisco. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated diciembre 15, 2025.

The most flights from USSC to SFO are scheduled on a Monday (1 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (1 on average).

Related info for your journey

Find useful and relevant information for your journey from South Carolina to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Francisco from South Carolina?

    Most people fly into San Francisco (SFO) if they book a flight to San Francisco from South Carolina. San Francisco is conveniently located just 11.8 mi from San Francisco’s city center.

  • How long is the flight from South Carolina to San Francisco?

    United Airlines, Alaska Airlines, and JetBlue can get you from South Carolina to San Francisco in just under 9h 15m. Your travel time can differ by up to 9h 50m. The distance between South Carolina and San Francisco is about 2389 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from South Carolina to San Francisco one-way?

    One-way options have recently been found by users for as low as $71 on Breeze Airways. Other airlines that offer cheap prices include American Airlines from $108 and Southwest from $138 one-way.

  • What are the most popular routes from South Carolina to San Francisco?

    The most popular route from South Carolina to San Francisco is Charlotte Douglas - San Francisco. You may also consider Charleston - San Francisco or Greenville - San Francisco.

  • Can I find deals for flights from South Carolina to San Francisco that include hotel bookings?

    Yes. In addition to deals on South Carolina to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to San Francisco.

  • Can I find deals for business class flights from South Carolina to San Francisco?

    Yes. Cheapflights offers flight deals from South Carolina to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to San Francisco?

    Currently, November is the cheapest month in which you can book a flight from South Carolina to San Francisco (average of $160). Flying from South Carolina to San Francisco in March is currently the most expensive (average of $271). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Roseville
South San Francisco
Santa Cruz
Livermore
Turlock
Manteca
Watsonville
Redwood City
Sunnyvale
Santa Clara
San Bruno
Daly City
San Carlos
Vallejo
Hollister
San Ramon
Foster City
Union City
Davis
Emeryville

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Alternative routes for South Carolina to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from South Carolina to San Francisco

Discover the top 5 airlines that operate flights from South Carolina to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$161Average$289FlexibilityNo cancel feeOn-timeN/A
DeltaCheapest$239Average$427FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$243Average$428FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$263Average$440FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$307Average$442FlexibilityNo cancel feeOn-time63%

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