San Francisco

$109+ Cheap flights from South Carolina to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/22. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — SFO
Apr 5 — Apr 121
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Cheap flight deals from South Carolina to San Francisco

Keep the following information in mind while searching for South Carolina to San Francisco flight deals. Data was last updated March 31, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$173
(Priceline)

One-way from

$109
(American Airlines)

Popular in

June

Cheapest in

April

Average price

$506
Provider with most accurate pricing for Myrtle Beach Intl-San Francisco flight deals.
Provider most trusted by Cheapflights users for Myrtle Beach Intl-San Francisco flights.
From South Carolina to San Francisco
One-way flight from South Carolina to San Francisco
Highest demand for flights based on searches. 10% potential increase in price ($53 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
Average for round-trip flights in March 2025

Find flight deals from South Carolina to San Francisco

Cheapest flights from South Carolina to San Francisco
Explore the most affordable flight options available from South Carolina to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 31, 2025.

This Priceline deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/36:25 amCHS - SFO
1 stop8h 14mBreeze Airways
Tue 5/612:33 pmSFO - CHS
1 stop6h 50mBreeze Airways
Deal found 3/30$173
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/294:10 pmCHS - SFO
1 stop9h 41mAmerican Airlines
Tue 5/611:49 pmSFO - CHS
1 stop8h 18mAmerican Airlines
Deal found 3/30$217
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/221:10 pmSAV - SFO
1 stop10h 55mAmerican Airlines
Mon 4/2812:21 amSFO - SAV
1 stop7h 17mAmerican Airlines
Deal found 3/30$219
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/264:13 pmAGS - SFO
1 stop9h 27mAmerican Airlines
Wed 10/11:47 pmSFO - AGS
1 stop7h 17mAmerican Airlines
Deal found 3/30$239
This JetBlue deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/255:24 pmCHS - SFO
1 stop10h 07mJetBlue
Mon 5/126:00 amSFO - CHS
1 stop10h 48mJetBlue
Deal found 3/30$259
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/315:35 amCHS - SFO
1 stop7h 40mDelta
Mon 6/910:25 pmSFO - CHS
1 stop9h 15mDelta
Deal found 3/30$277
This Frontier deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/117:38 pmCLT - SFO
1 stop8h 06mFrontier
Sat 4/196:00 amSFO - CLT
1 stop9h 57mFrontier
Deal found 3/30$278
This United Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/15:00 pmSAV - SFO
1 stop9h 59mUnited Airlines
Sat 5/312:10 amSFO - SAV
1 stop7h 27mUnited Airlines
Deal found 3/31$279
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/24:19 pmCAE - SFO
1 stop9h 33mAmerican Airlines
Sat 7/265:23 amSFO - CAE
1 stop7h 22mAmerican Airlines
Deal found 3/31$279
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/203:13 pmHHH - SFO
1 stop7h 28mAmerican Airlines
Mon 6/212:21 amSFO - HHH
1 stop8h 59mAmerican Airlines
Deal found 3/30$279
This CheapOair deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/254:21 pmCLT - SFO
1 stop23h 58mMultiple Airlines
Sun 5/46:09 pmSFO - CLT
1 stop20h 33mMultiple Airlines
Deal found 3/29$294
This Alaska Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/86:45 pmCHS - SFO
1 stop16h 33mAlaska Airlines
Mon 10/139:40 pmSFO - CHS
1 stop16h 51mAlaska Airlines
Deal found 3/31$296

Cheapflights Fare Finder

Customize your flight search to find flights from South Carolina to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2025.
Use the filters below to find and compare flights from South Carolina to San Francisco that are best for you.

Fly from

South Carolina

Fly to

San Francisco

Route

Depart

Return

Price

CharlestonSan Francisco

CHS - SFO

CHSSFO

Charleston

Sat 5/3

6:25 am-11:39 am

1 stop8h 14m

San Francisco

Tue 5/6

12:33 pm-10:23 pm

1 stop6h 50m

$173

CharlestonSan Francisco

CHS - SFO

CHSSFO

Charleston

Tue 4/29

4:10 pm-10:51 pm

1 stop9h 41m

San Francisco

Tue 5/6

11:49 pm-11:07 am

1 stop8h 18m

$217

SavannahSan Francisco

SAV - SFO

SAVSFO

Savannah/Hilton Head

Tue 4/22

1:10 pm-9:05 pm

1 stop10h 55m

San Francisco

Mon 4/28

12:21 am-10:38 am

1 stop7h 17m

$219

AugustaSan Francisco

AGS - SFO

AGSSFO

Augusta Bush Field

Fri 9/26

4:13 pm-8:29 pm

1 stop7h 16m

San Francisco

Wed 10/1

1:47 pm-12:04 am

1 stop7h 17m

$239

CharlestonSan Francisco

CHS - SFO

CHSSFO

Charleston

Fri 4/25

5:24 pm-12:31 am

1 stop10h 07m

San Francisco

Mon 5/12

6:00 am-7:48 pm

1 stop10h 48m

$259

CharlestonSan Francisco

CHS - SFO

CHSSFO

Charleston

Sat 5/31

5:35 am-10:15 am

1 stop7h 40m

San Francisco

Tue 6/10

9:35 pm-8:35 am

1 stop8h 00m

$277

CharlotteSan Francisco

CLT - SFO

CLTSFO

Charlotte Douglas

Fri 4/11

7:38 pm-12:44 am

1 stop8h 06m

San Francisco

Sat 4/19

6:00 am-6:57 pm

1 stop9h 57m

$278

SavannahSan Francisco

SAV - SFO

SAVSFO

Savannah/Hilton Head

Thu 5/1

6:55 pm-1:12 am

1 stop9h 17m

San Francisco

Sun 5/4

10:50 pm-10:37 am

1 stop8h 47m

$279

ColumbiaSan Francisco

CAE - SFO

CAESFO

Columbia Metropolitan

Wed 7/2

4:19 pm-10:52 pm

1 stop9h 33m

San Francisco

Sat 7/26

5:23 am-3:45 pm

1 stop7h 22m

$279

Hilton Head IslandSan Francisco

HHH - SFO

HHHSFO

Hilton Head Island

Tue 5/20

3:13 pm-7:41 pm

1 stop7h 28m

San Francisco

Mon 6/2

12:21 am-12:20 pm

1 stop8h 59m

$279

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/31

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to San Francisco

What is the cheapest month to book a flight from South Carolina to San Francisco?

Currently, January is the cheapest month in which you can book a flight from South Carolina to San Francisco (average of $276). Flying from South Carolina to San Francisco in June is currently the most expensive (average of $393). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to SFO?

Find hourly flight availability from South Carolina to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 31, 2025.

When flying from South Carolina to San Francisco, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in San Francisco by month

Plan your trip to San Francisco by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in San Francisco ranges from 0.0 - 4.4 inches per month. January is typically the wettest month, when rainfall can reach 4.4 in. July is typically the driest time to visit San Francisco when rainfall is around 0.0 in.

Temperature in San Francisco by month

Plan your trip to San Francisco by taking into account the average temperature totals by month.

If weather is an important factor for your trip to San Francisco, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated March 31, 2025.
Read through reviews of airlines operating flights from South Carolina to San Francisco, such as Breeze Airways, Alaska Airlines and Southwest. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Food

6.7

Comfort

8.2

Entertainment

6.6

Crew

8.8

Boarding

8.3

Overall

8.1

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Food

6.7

Comfort

8.2

Entertainment

6.6

Crew

8.8

Boarding

8.3

Overall

8.1

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Food

6.7

Comfort

8.2

Entertainment

6.6

Crew

8.8

Boarding

8.3

Overall

8.1

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Food

6.7

Comfort

8.2

Entertainment

6.6

Crew

8.8

Boarding

8.3

Overall

8.1

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
8.0
Very good

Food

6.7

Comfort

8.2

Entertainment

6.6

Crew

8.8

Boarding

8.3

Overall

8.1

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Food

6.7

Comfort

8.2

Entertainment

6.6

Crew

8.8

Boarding

8.3

Overall

8.1

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Related info for your journey

Find useful and relevant information for your journey from South Carolina to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to San Francisco from South Carolina?

    Most people fly into San Francisco (SFO) if they book a flight to San Francisco from South Carolina. San Francisco is conveniently located just 11.8 mi from San Francisco’s city center.

  • What are the cheapest airlines to fly from South Carolina to San Francisco one-way?

    One-way options have recently been found by users for as low as $109 on American Airlines. Other airlines that offer cheap prices include Breeze Airways from $121 and Delta from $139 one-way.

  • What are the most popular routes from South Carolina to San Francisco?

  • Can I find deals for flights from South Carolina to San Francisco that include hotel bookings?

    Yes. In addition to deals on South Carolina to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to San Francisco.

  • Can I find deals for business class flights from South Carolina to San Francisco?

    Yes. Cheapflights offers flight deals from South Carolina to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to San Francisco?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to San Francisco (average of $276). Flying from South Carolina to San Francisco in June is currently the most expensive (average of $393). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near South Carolina?

Book flights to South Carolina if you plan to visit one of these locations
Roseville
Mountain View
Santa Cruz
Turlock
Fairfield
South San Francisco
Manteca
Sausalito
Richmond
Watsonville
Hollister
Milpitas
Antioch
Hayward
Vallejo
Newark
Alameda
Sunnyvale
Campbell
Daly City

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.

Top 5 airlines flying from South Carolina to San Francisco

Discover the top 5 airlines that operate flights from South Carolina to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$182Average$323FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$218Average$472FlexibilityNo cancel feeOn-time71%
DeltaCheapest$250Average$449FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$256Average$466FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$298Average$442FlexibilityNo cancel feeOn-time63%
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