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$225+ Cheap flights from Santo Domingo (SDQ) to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/29. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — SFO
Feb 27 — Mar 61
Thu 2/27
Thu 3/6
1 adult, Economy
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The best prices from Santo Domingo Las Americas to San Francisco are usually found in February or December, booked 7 days in advance, depart on a Thursday or Wednesday and return on a Tuesday

Cheap flight deals from Santo Domingo to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 22, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$431
(eDestinos)

One-way from

$225
(Kiwi.com)

Popular in

May

Cheapest in

February

Average price

$551
Provider with most accurate pricing for Santo Domingo Las Americas-San Francisco flight deals.
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Provider most trusted by Cheapflights users for Santo Domingo Las Americas-San Francisco flights.
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From Santo Domingo Las Americas to San Francisco
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One-way flight from Santo Domingo Las Americas to San Francisco
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Highest demand for flights based on searches. 14% potential increase in price ($119 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($19 potential savings vs. average RT price).
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Average for round-trip flights in February 2025
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Find flight deals from Santo Domingo to San Francisco

Cheapest flights from Santo Domingo to San Francisco
Explore the most affordable flight options available from Santo Domingo to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 22, 2025.

This eDestinos deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/3010:19 amSDQ - SFO
2 stops41h 12mMultiple Airlines
Thu 5/811:50 pmSFO - SDQ
2 stops32h 13mMultiple Airlines
Deal found 2/21$431
This JetBlue deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/241:39 pmSDQ - SFO
1 stop12h 46mJetBlue
Sat 5/310:10 pmSFO - SDQ
1 stop12h 09mJetBlue
Deal found 2/21$511
This eDestinos deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1112:02 pmSDQ - SFO
2 stops37h 52mFrontier
Sat 4/1911:59 pmSFO - SDQ
2 stops31h 43mFrontier
Deal found 2/21$529
This eDestinos deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/311:03 amSDQ - SFO
1 stop28h 27mAeromexico
Tue 11/111:00 pmSFO - SDQ
1 stop14h 23mAeromexico
Deal found 2/21$627
This Delta deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/172:43 pmSDQ - SFO
1 stop11h 48mDelta
Wed 4/309:00 amSFO - SDQ
1 stop12h 50mDelta
Deal found 2/21$671
This United Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/203:10 pmSDQ - SFO
2 stops36h 54mUnited Airlines
Tue 10/2810:45 pmSFO - SDQ
1 stop10h 55mUnited Airlines
Deal found 2/21$676
This American Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1612:15 pmSDQ - SFO
2 stops13h 36mAmerican Airlines
Wed 4/301:18 pmSFO - SDQ
1 stop18h 57mAmerican Airlines
Deal found 2/21$695
This Expedia deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2011:45 amSDQ - SFO
2 stops27h 50mAvianca
Tue 10/282:20 pmSFO - SDQ
2 stops24h 00mAvianca
Deal found 2/21$728
This Copa Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/168:52 amSDQ - SFO
1 stop17h 48mCopa Airlines
Tue 4/291:40 amSFO - SDQ
1 stop17h 23mCopa Airlines
Deal found 2/21$855

Find flights from Santo Domingo to San Francisco within your budget

Customize your flight search to find flights from Santo Domingo to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 22, 2025.

Fly from

Santo Domingo

Fly to

San Francisco

Route

Depart

Return

Price

Santo DomingoSan Francisco

SDQ - SFO

SDQSFO

Santo Domingo Las Americas

Wed 4/30

10:19 am-12:31 am

2 stops41h 12m

San Francisco

Thu 5/8

11:50 pm-11:03 am

2 stops32h 13m

$431

Santo DomingoSan Francisco

SDQ - SFO

SDQSFO

Santo Domingo Las Americas

Thu 4/24

1:39 pm-11:25 pm

1 stop12h 46m

San Francisco

Sat 5/3

10:10 pm-1:19 pm

1 stop12h 09m

$511

Santo DomingoSan Francisco

SDQ - SFO

SDQSFO

Santo Domingo Las Americas

Fri 4/11

12:02 pm-10:54 pm

2 stops37h 52m

San Francisco

Sat 4/19

11:59 pm-10:42 am

2 stops31h 43m

$529

Santo DomingoSan Francisco

SDQ - SFO

SDQSFO

Santo Domingo Las Americas

Wed 4/30

11:01 am-9:15 pm

1 stop13h 14m

San Francisco

Thu 5/8

2:06 pm-6:45 am

2 stops13h 39m

$627

Santo DomingoSan Francisco

SDQ - SFO

SDQSFO

Santo Domingo Las Americas

Thu 4/17

2:43 pm-11:31 pm

1 stop11h 48m

San Francisco

Wed 4/30

9:00 am-12:50 am

1 stop12h 50m

$671

Santo DomingoSan Francisco

SDQ - SFO

SDQSFO

Santo Domingo Las Americas

Wed 4/16

12:15 pm-10:51 pm

2 stops13h 36m

San Francisco

Wed 4/30

1:18 pm-11:15 am

1 stop18h 57m

$695

Santo DomingoSan Francisco

SDQ - SFO

SDQSFO

Santo Domingo Las Americas

Wed 4/16

8:52 am-11:40 pm

1 stop17h 48m

San Francisco

Tue 4/29

1:40 am-10:03 pm

1 stop17h 23m

$855

Santo DomingoSan Francisco

SDQ - SFO

SDQSFO

Santo Domingo Las Americas

Tue 4/29

3:35 pm-2:38 pm

2 stops26h 03m

$225

Santo DomingoSan Francisco

SDQ - SFO

SDQSFO

Santo Domingo Las Americas

Fri 3/7

1:04 pm-10:52 pm

2 stops37h 48m

$229

Santo DomingoSan Francisco

SDQ - SFO

SDQSFO

Santo Domingo Las Americas

Thu 5/1

10:00 am-11:59 pm

1 stop16h 59m

$286

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/22

Showing 1-10 of 16 results
1
2
  • Most accurate provider: When it comes to deals on Santo Domingo-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santo Domingo-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santo Domingo-San Francisco flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santo Domingo-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santo Domingo-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santo Domingo to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Santo Domingo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Santo Domingo to San Francisco

Get recent, data-driven insights about flights from Santo Domingo to San Francisco including ideal travel times, pricing trends, and more.

How far ahead should I book a flight from Santo Domingo to San Francisco?

Use this chart to determine the optimal time to book a round-trip flight from Santo Domingo to San Francisco. Price data was last updated on February 14, 2025.

Booking 7 days in advance of your planned departure date is, on average, the best time to get cheap flights from Santo Domingo to San Francisco. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Santo Domingo to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Santo Domingo to San Francisco (average of $276). Flying from Santo Domingo to San Francisco in June is currently the most expensive (average of $403). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SDQ to SFO?

Find hourly flight availability from Santo Domingo to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 22, 2025.

It’s typically best to fly out from Santo Domingo to San Francisco in the evening. Doing so could potentially save you 67% on the flight price compared to flying at noon, which is usually more expensive.

Rainfall in San Francisco by month

Plan your trip to San Francisco by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in San Francisco ranges from 0.0 - 4.4 inches per month. January is typically the wettest month, when rainfall can reach 4.4 in. July is typically the driest time to visit San Francisco when rainfall is around 0.0 in.

Temperature in San Francisco by month

Plan your trip to San Francisco by taking into account the average temperature totals by month.

If weather is an important factor for your trip to San Francisco, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated February 22, 2025.
Delta
8.0
Very good
8,203 reviews

Overall

8.0

Boarding

8.2

Entertainment

7.9

Crew

8.5

Food

7.3

Comfort

8.0

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta
8.0
Very good
8,203 reviews
Delta
8.0
Very good
8,203 reviews

Overall

8.0

Boarding

8.2

Entertainment

7.9

Crew

8.5

Food

7.3

Comfort

8.0

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Copa Airlines
7.6
Good
1,502 reviews
Delta
8.0
Very good
8,203 reviews

Overall

8.0

Boarding

8.2

Entertainment

7.9

Crew

8.5

Food

7.3

Comfort

8.0

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Aeromexico
7.5
Good
1,769 reviews
Delta
8.0
Very good
8,203 reviews

Overall

8.0

Boarding

8.2

Entertainment

7.9

Crew

8.5

Food

7.3

Comfort

8.0

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

JetBlue
7.4
Good
3,068 reviews
Delta
8.0
Very good
8,203 reviews

Overall

8.0

Boarding

8.2

Entertainment

7.9

Crew

8.5

Food

7.3

Comfort

8.0

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

United Airlines
7.4
Good
8,754 reviews
Delta
8.0
Very good
8,203 reviews

Overall

8.0

Boarding

8.2

Entertainment

7.9

Crew

8.5

Food

7.3

Comfort

8.0

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Santo Domingo to San Francisco round-trip?

    Our cheapest airline available from Santo Domingo to San Francisco is JetBlue. Our recent data shows that you can find tickets from as low as $511 on this airline. Additional options worth looking into are Frontier and Aeromexico, starting at $529 and $627 round-trip. JetBlue is currently priced 25% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Santo Domingo to San Francisco one-way?

    For one-way options, check prices for Frontier. According to our data, you can fly for as low as $229. Users have also found prices from $286 and $338 on JetBlue and Avianca, respectively.

  • Can I find deals for flights from Santo Domingo to San Francisco that include hotel bookings?

    Yes. In addition to deals on Santo Domingo to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santo Domingo to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to San Francisco.

  • Can I find deals for business class flights from Santo Domingo to San Francisco?

    Yes. Cheapflights offers flight deals from Santo Domingo to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santo Domingo to San Francisco?

    Currently, January is the cheapest month in which you can book a flight from Santo Domingo to San Francisco (average of $276). Flying from Santo Domingo to San Francisco in June is currently the most expensive (average of $403). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Roseville
Mountain View
Turlock
Santa Cruz
Fairfield
Manteca
Sausalito
Watsonville
Hayward
Richmond
Hollister
South San Francisco
Antioch
Milpitas
Vallejo
Newark
Alameda
Campbell
Pacific Grove
Sunnyvale

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Alternative routes for Santo Domingo to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.
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Santo Domingo to Santa Ana flights
Santiago de los Caballeros to Santa Ana flights

Top 3 airlines flying from Santo Domingo to San Francisco

Discover the top 3 airlines that operate flights from Santo Domingo to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 22, 2025.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$237Average$654FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$480Average$1,028FlexibilityNo cancel feeOn-time71%
DeltaCheapest$584Average$798FlexibilityNo cancel feeOn-timeN/A
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