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$289+ Cheap flights from Santo Domingo (SDQ) to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/24. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — SFO
Apr 22 — Apr 291
Tue 4/22
Tue 4/29
1 adult, Economy
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Cheapflights Tip: The best prices from Santo Domingo Las Americas to San Francisco are usually found in September or December, booked 7 days in advance, depart on a Thursday or Wednesday and return on a Tuesday

Cheap flight deals from Santo Domingo to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 17, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$675
(eDestinos)

One-way from

$297
(JetBlue)

Popular in

February

Cheapest in

September

Average price

$641
Provider with most accurate pricing for Santo Domingo Las Americas-San Francisco flight deals.
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Provider most trusted by Cheapflights users for Santo Domingo Las Americas-San Francisco flights.
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From Santo Domingo Las Americas to San Francisco
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One-way flight from Santo Domingo Las Americas to San Francisco
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High demand for flights, 0% potential price rise
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Cheapest flight prices on average. 1% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Santo Domingo to San Francisco

Cheapest flights from Santo Domingo to San Francisco
Explore the most affordable flight options available from Santo Domingo to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.

This Avianca deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/1611:45 amSDQ - SFO
2 stops15h 10mAvianca
Fri 8/222:20 pmSFO - SDQ
2 stops17h 30mAvianca
Deal found 4/16$634
This Kiwi.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/166:17 pmSDQ - SFO
1 stop32h 23mMultiple Airlines
Wed 4/2311:38 pmSFO - SDQ
2 stops37h 51mMultiple Airlines
Deal found 4/15$635
This Copa Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/172:04 pmSDQ - SFO
1 stop12h 36mCopa Airlines
Tue 4/291:40 amSFO - SDQ
1 stop17h 23mCopa Airlines
Deal found 4/16$674
This JetBlue deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/162:31 pmSDQ - SFO
1 stop12h 05mJetBlue
Fri 8/2211:30 amSFO - SDQ
1 stop10h 45mJetBlue
Deal found 4/15$684
This Booking.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/271:43 pmSDQ - SFO
2 stops35h 52mFrontier
Fri 5/21:39 pmSFO - SDQ
2 stops19h 09mFrontier
Deal found 4/17$703
This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/1611:30 amSDQ - SFO
2 stops14h 31mAmerican Airlines
Thu 8/2112:44 amSFO - SDQ
2 stops10h 56mAmerican Airlines
Deal found 4/15$760
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/177:00 amSDQ - SFO
1 stop14h 43mDelta
Wed 5/74:15 pmSFO - SDQ
2 stops18h 01mDelta
Deal found 4/16$1,161
This Aeromexico deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1811:12 amSDQ - SFO
1 stop12h 46mAeromexico
Tue 6/2412:41 pmSFO - SDQ
2 stops15h 01mAeromexico
Deal found 4/17$1,504

Cheapflights Fare Finder

Customize your flight search to find flights from Santo Domingo to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
Use the filters below to find and compare flights from Santo Domingo to San Francisco that are best for you.

Fly from

Santo Domingo

Fly to

San Francisco

Route

Depart

Return

Price

Santo DomingoSan Francisco

SDQ - SFO

SDQSFO

Santo Domingo Las Americas

Sat 8/16

11:45 am-11:55 pm

2 stops15h 10m

San Francisco

Fri 8/22

2:20 pm-10:50 am

2 stops17h 30m

$634

Santo DomingoSan Francisco

SDQ - SFO

SDQSFO

Santo Domingo Las Americas

Sat 8/16

2:31 pm-11:36 pm

1 stop12h 05m

San Francisco

Fri 8/22

11:30 am-1:15 am

1 stop10h 45m

$684

Santo DomingoSan Francisco

SDQ - SFO

SDQSFO

Santo Domingo Las Americas

Sun 4/27

1:43 pm-10:35 pm

2 stops35h 52m

San Francisco

Fri 5/2

1:39 pm-11:48 am

2 stops19h 09m

$703

Santo DomingoSan Francisco

SDQ - SFO

SDQSFO

Santo Domingo Las Americas

Sat 8/16

11:30 am-11:01 pm

2 stops14h 31m

San Francisco

Thu 8/21

12:44 am-2:40 pm

2 stops10h 56m

$760

Santo DomingoSan Francisco

SDQ - SFO

SDQSFO

Santo Domingo Las Americas

Sat 8/16

8:55 am-11:40 pm

1 stop17h 45m

San Francisco

Thu 8/21

1:28 am-4:17 pm

1 stop11h 49m

$806

Santo DomingoSan Francisco

SDQ - SFO

SDQSFO

Santo Domingo Las Americas

Sun 4/27

1:43 pm-10:35 pm

2 stops35h 52m

San Francisco

Fri 5/2

2:20 pm-2:50 pm

1 stop21h 30m

$888

Santo DomingoSan Francisco

SDQ - SFO

SDQSFO

Santo Domingo Las Americas

Wed 6/18

11:12 am-8:58 pm

1 stop12h 46m

San Francisco

Tue 6/24

12:41 pm-6:42 am

2 stops15h 01m

$1,504

Santo DomingoSan Francisco

SDQ - SFO

SDQSFO

Santo Domingo Las Americas

Thu 7/24

2:31 pm-11:36 pm

1 stop12h 05m

$289

Santo DomingoSan Francisco

SDQ - SFO

SDQSFO

Santo Domingo Las Americas

Sun 5/4

3:35 pm-11:06 pm

2 stops34h 31m

$300

Santo DomingoSan Francisco

SDQ - SFO

SDQSFO

Santo Domingo Las Americas

Thu 7/24

11:45 am-10:45 pm

2 stops14h 00m

$326

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/16

Showing 1-10 of 13 results
1
2

Compare providers for flights from Santo Domingo to San Francisco

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santo Domingo to San Francisco in April.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*2 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Santo Domingo-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santo Domingo-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santo Domingo-San Francisco flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santo Domingo-San Francisco flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santo Domingo-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santo Domingo to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Santo Domingo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to San Francisco

How far ahead should I book a flight from Santo Domingo to San Francisco?

Use this chart to determine the optimal time to book a round-trip flight from Santo Domingo to San Francisco. Price data was last updated on April 11, 2025.

Booking 7 days in advance of your planned departure date is, on average, the best time to get cheap flights from Santo Domingo to San Francisco. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Santo Domingo to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Santo Domingo to San Francisco (average of $276). Flying from Santo Domingo to San Francisco in June is currently the most expensive (average of $393). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SDQ to SFO?

Find hourly flight availability from Santo Domingo to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 17, 2025.

It’s typically best to fly out from Santo Domingo to San Francisco in the evening. Doing so could potentially save you 67% on the flight price compared to flying at noon, which is usually more expensive.

Rainfall in San Francisco by month

Plan your trip to San Francisco by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in San Francisco ranges from 0.0 - 4.4 inches per month. January is typically the wettest month, when rainfall can reach 4.4 in. July is typically the driest time to visit San Francisco when rainfall is around 0.0 in.

Temperature in San Francisco by month

Plan your trip to San Francisco by taking into account the average temperature totals by month.

If weather is an important factor for your trip to San Francisco, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated April 17, 2025.
To help decide which airline to fly from Santo Domingo to San Francisco, see what other customers have to say about Copa Airlines, Aeromexico and JetBlue. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,409 reviews

Overall

7.6

Food

6.8

Boarding

7.8

Entertainment

6.8

Comfort

7.4

Crew

8.1

Reviews

1 / 20
4.0
Okay

Anonymous,Mar 2025

PTY - JFK

There was no chance for me to choose a seat even if I were willing to pay extra for it when I was doing the check-in on line. My seats were the last row on the plane and they didn't have enough food to give me. I had to eat what was left after everybody else had their choice of food. This is unacceptable. Everyone should have a choice. I paid money just like everybody else. Never had this happened on any other airlines even if my seats were last row on the plane.
Copa Airlines
7.6
Good
1,409 reviews
Copa Airlines
7.6
Good
1,409 reviews

Overall

7.6

Food

6.8

Boarding

7.8

Entertainment

6.8

Comfort

7.4

Crew

8.1

Reviews

1 / 20
4.0
Okay

Anonymous,Mar 2025

PTY - JFK

There was no chance for me to choose a seat even if I were willing to pay extra for it when I was doing the check-in on line. My seats were the last row on the plane and they didn't have enough food to give me. I had to eat what was left after everybody else had their choice of food. This is unacceptable. Everyone should have a choice. I paid money just like everybody else. Never had this happened on any other airlines even if my seats were last row on the plane.
Aeromexico
7.5
Good
1,699 reviews
Copa Airlines
7.6
Good
1,409 reviews

Overall

7.6

Food

6.8

Boarding

7.8

Entertainment

6.8

Comfort

7.4

Crew

8.1

Reviews

1 / 20
4.0
Okay

Anonymous,Mar 2025

PTY - JFK

There was no chance for me to choose a seat even if I were willing to pay extra for it when I was doing the check-in on line. My seats were the last row on the plane and they didn't have enough food to give me. I had to eat what was left after everybody else had their choice of food. This is unacceptable. Everyone should have a choice. I paid money just like everybody else. Never had this happened on any other airlines even if my seats were last row on the plane.
JetBlue
7.3
Good
2,926 reviews
Copa Airlines
7.6
Good
1,409 reviews

Overall

7.6

Food

6.8

Boarding

7.8

Entertainment

6.8

Comfort

7.4

Crew

8.1

Reviews

1 / 20
4.0
Okay

Anonymous,Mar 2025

PTY - JFK

There was no chance for me to choose a seat even if I were willing to pay extra for it when I was doing the check-in on line. My seats were the last row on the plane and they didn't have enough food to give me. I had to eat what was left after everybody else had their choice of food. This is unacceptable. Everyone should have a choice. I paid money just like everybody else. Never had this happened on any other airlines even if my seats were last row on the plane.
American Airlines
7.2
Good
10,000 reviews
Copa Airlines
7.6
Good
1,409 reviews

Overall

7.6

Food

6.8

Boarding

7.8

Entertainment

6.8

Comfort

7.4

Crew

8.1

Reviews

1 / 20
4.0
Okay

Anonymous,Mar 2025

PTY - JFK

There was no chance for me to choose a seat even if I were willing to pay extra for it when I was doing the check-in on line. My seats were the last row on the plane and they didn't have enough food to give me. I had to eat what was left after everybody else had their choice of food. This is unacceptable. Everyone should have a choice. I paid money just like everybody else. Never had this happened on any other airlines even if my seats were last row on the plane.

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Santo Domingo to San Francisco round-trip?

    Our cheapest airline available from Santo Domingo to San Francisco is JetBlue. Our recent data shows that you can find tickets from as low as $801 on this airline. Additional options worth looking into are Copa Airlines and American Airlines, starting at $818 and $876 round-trip.

  • What are the cheapest airlines to fly from Santo Domingo to San Francisco one-way?

    For one-way options, check prices for JetBlue. According to our data, you can fly for as low as $297. Users have also found prices from $476 and $833 on American Airlines and Aeromexico, respectively.

  • Can I find deals for flights from Santo Domingo to San Francisco that include hotel bookings?

    Yes. In addition to deals on Santo Domingo to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santo Domingo to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to San Francisco.

  • Can I find deals for business class flights from Santo Domingo to San Francisco?

    Yes. Cheapflights offers flight deals from Santo Domingo to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santo Domingo to San Francisco?

    Currently, January is the cheapest month in which you can book a flight from Santo Domingo to San Francisco (average of $276). Flying from Santo Domingo to San Francisco in June is currently the most expensive (average of $393). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Roseville
Mountain View
Santa Cruz
Turlock
South San Francisco
Fairfield
Manteca
Sausalito
Richmond
Watsonville
Hollister
Milpitas
Antioch
Vallejo
Newark
Hayward
Alameda
Sunnyvale
Livermore
Campbell

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Top 3 airlines flying from Santo Domingo to San Francisco

Discover the top 3 airlines that operate flights from Santo Domingo to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$430Average$673FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$480Average$914FlexibilityNo cancel feeOn-time71%
DeltaCheapest$584Average$798FlexibilityNo cancel feeOn-timeN/A

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