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$350+ Cheap flights from Prague (PRG) to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/15. Fares are subject to change and may not be available on all flights or dates of travel.
PRG — SFO
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Find cheap flights from Prague to San Francisco with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

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Cheapflights Tip: The best prices from Václav Havel Prague to San Francisco are usually found in November or October, booked 84 days in advance, depart on a Monday or Tuesday and return on a Wednesday

Cheap flight deals from Prague to San Francisco

Cheapest flights from Prague to San Francisco
Explore the most affordable flight options available from Prague to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/253:10 pmPRG - SFO
1 stop33h 45mLufthansa
Thu 1/19:40 pmSFO - PRG
1 stop15h 45mLufthansa
Deal found 12/9$635
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/253:10 pmPRG - SFO
1 stop14h 00mLufthansa
Sun 12/289:40 pmSFO - PRG
1 stop15h 45mLufthansa
Deal found 12/11$637
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/253:10 pmPRG - SFO
1 stop14h 00mLufthansa
Wed 12/319:40 pmSFO - PRG
1 stop15h 45mLufthansa
Deal found 12/11$638
This Booking.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/263:15 pmPRG - SFO
1 stop13h 55mLufthansa
Thu 1/11:30 pmSFO - PRG
1 stop23h 55mLufthansa
Deal found 12/11$663
This Kiwi.com deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:45 amPRG - SFO
2 stops19h 15mMultiple Airlines
Wed 12/316:50 pmSFO - PRG
1 stop14h 15mMultiple Airlines
Deal found 12/9$665
This United Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/253:10 pmPRG - SFO
1 stop33h 45mUnited Airlines
Tue 12/307:25 pmSFO - PRG
1 stop33h 30mUnited Airlines
Deal found 12/9$670
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/253:10 pmPRG - SFO
1 stop33h 45mMultiple Airlines
Mon 12/297:25 pmSFO - PRG
1 stop14h 35mMultiple Airlines
Deal found 12/11$671
This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:50 amPRG - SFO
2 stops26h 13mUnited Airlines
Wed 12/317:25 pmSFO - PRG
1 stop33h 30mUnited Airlines
Deal found 12/11$675

Find flight deals from Prague to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Prague (PRG) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$623
(Gotogate)

One-way from

$350
(LEVEL)

Popular in

July

Cheapest in

November

Average price

$727
Provider with most accurate pricing for Václav Havel Prague-San Francisco flight deals.
Search Deals
Provider most trusted by Cheapflights users for Václav Havel Prague-San Francisco flights.
Search Deals
From Václav Havel Prague to San Francisco
Search Deals
One-way flight from Václav Havel Prague to San Francisco
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($35 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Prague to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Prague to San Francisco that are best for you.

Fly from

Prague

Fly to

San Francisco

Route

Depart

Return

Price

PragueSan Francisco

PRG - SFO

PRGSFO

Václav Havel Prague

Thu 5/7

7:10 am-1:50 pm

1 stop15h 40m

San Francisco

Sat 5/23

10:15 pm-9:40 pm

1 stop14h 25m

$625

PragueSan Francisco

PRG - SFO

PRGSFO

Václav Havel Prague

Thu 1/15

10:25 am-3:55 pm

1 stop14h 30m

San Francisco

Wed 1/28

5:25 pm-7:00 pm

2 stops16h 35m

$626

PragueSan Francisco

PRG - SFO

PRGSFO

Václav Havel Prague

Thu 5/7

6:00 am-11:45 am

1 stop14h 45m

San Francisco

Sat 5/23

6:05 am-10:55 am

2 stops19h 50m

$631

PragueSan Francisco

PRG - SFO

PRGSFO

Václav Havel Prague

Fri 3/13

10:25 am-3:35 pm

1 stop13h 10m

San Francisco

Mon 3/16

5:40 pm-2:20 pm

1 stop12h 40m

$634

PragueSan Francisco

PRG - SFO

PRGSFO

Václav Havel Prague

Fri 1/23

6:00 am-11:50 am

1 stop14h 50m

San Francisco

Wed 1/28

8:00 am-11:40 am

2 stops18h 40m

$635

PragueSan Francisco

PRG - SFO

PRGSFO

Václav Havel Prague

Tue 3/3

6:00 am-11:50 am

1 stop14h 50m

San Francisco

Wed 3/11

4:40 pm-5:05 pm

1 stop16h 25m

$636

PragueSan Francisco

PRG - SFO

PRGSFO

Václav Havel Prague

Thu 1/15

10:30 am-6:45 pm

1 stop17h 15m

San Francisco

Wed 1/28

4:30 pm-8:40 pm

2 stops19h 10m

$637

PragueSan Francisco

PRG - SFO

PRGSFO

Václav Havel Prague

Thu 1/15

2:30 pm-11:50 am

1 stop30h 20m

San Francisco

Wed 1/28

7:00 am-11:40 am

2 stops19h 40m

$637

PragueSan Francisco

PRG - SFO

PRGSFO

Václav Havel Prague

Wed 4/15

8:40 pm-6:00 pm

1 stop30h 20m

$350

PragueSan Francisco

PRG - SFO

PRGSFO

Václav Havel Prague

Mon 4/27

8:55 pm-1:50 pm

1 stop25h 55m

$377

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Showing 1-10 of 17 results
1
2

Compare providers for flights from Prague to San Francisco

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Prague to San Francisco in December.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
ExpediaPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Prague-San Francisco flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Prague-San Francisco flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Prague-San Francisco flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Prague-San Francisco flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Prague-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Prague to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Prague with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Prague to San Francisco

How far ahead should I book a flight from Prague to San Francisco?

Use this chart to determine the optimal time to book a round-trip flight from Prague to San Francisco. Price data was last updated on December 5, 2025.

The price you pay for your flight from Prague to San Francisco may vary depending on when you book. For the best chance of a lower fare, look to book 84 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Prague to San Francisco?

Currently, December is the cheapest month in which you can book a flight from Prague to San Francisco (average of $405). Flying from Prague to San Francisco in July is currently the most expensive (average of $571). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PRG to SFO?

Find hourly flight availability from Prague to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

When flying from Prague to San Francisco, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 34% versus a flight in the afternoon.

How much does it cost to fly round-trip from Prague to San Francisco?

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated December 12, 2025.
See what other customers who have flown with United Airlines, American Airlines, and Lufthansa from Prague to San Francisco have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,095 reviews

Boarding

7.7

Overall

7.4

Comfort

7.3

Crew

8.1

Food

6.6

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.
United Airlines
7.4
Good
9,095 reviews
United Airlines
7.4
Good
9,095 reviews

Boarding

7.7

Overall

7.4

Comfort

7.3

Crew

8.1

Food

6.6

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.
American Airlines
7.2
Good
11,050 reviews
United Airlines
7.4
Good
9,095 reviews

Boarding

7.7

Overall

7.4

Comfort

7.3

Crew

8.1

Food

6.6

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.
Lufthansa
6.8
Okay
7,626 reviews
United Airlines
7.4
Good
9,095 reviews

Boarding

7.7

Overall

7.4

Comfort

7.3

Crew

8.1

Food

6.6

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.
British Airways
6.7
Okay
7,571 reviews
United Airlines
7.4
Good
9,095 reviews

Boarding

7.7

Overall

7.4

Comfort

7.3

Crew

8.1

Food

6.6

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.
Condor
6.4
Okay
390 reviews
United Airlines
7.4
Good
9,095 reviews

Boarding

7.7

Overall

7.4

Comfort

7.3

Crew

8.1

Food

6.6

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.

Related info for your journey

Find useful and relevant information for your journey from Prague to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Prague to San Francisco?

    Departing from Prague to San Francisco will take you 13h 10m. Prague and San Francisco are separated by a distance of 5822 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Prague to San Francisco round-trip?

    Cheapflights users have booked flights from Prague to San Francisco round-trip from $300. Other airlines that can offer you cheap pricing are American Airlines, from $405, and British Airways, from $518. Condor is 55% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from Prague to San Francisco one-way?

    To fly one-way, consider booking your trip with Iberia, which is currently one of the cheapest options available, starting at $369. American Airlines flights start at $370 while deals on Condor start at $490 one-way.

  • Can I find deals for flights from Prague to San Francisco that include hotel bookings?

    Yes. In addition to deals on Prague to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Prague to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Prague to San Francisco.

  • Can I find deals for business class flights from Prague to San Francisco?

    Yes. Cheapflights offers flight deals from Prague to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Prague to San Francisco?

    Currently, December is the cheapest month in which you can book a flight from Prague to San Francisco (average of $405). Flying from Prague to San Francisco in July is currently the most expensive (average of $571). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Roseville
South San Francisco
Santa Cruz
Livermore
Turlock
Manteca
Watsonville
Sunnyvale
Santa Clara
San Bruno
Redwood City
Daly City
Vallejo
Hollister
Foster City
Union City
Davis
San Ramon
Burlingame
Milpitas

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Top 6 airlines flying from Prague to San Francisco

Discover the top 6 airlines that operate flights from Prague to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$405Average$571FlexibilityNo cancel feeOn-time71%
CondorCheapest$473Average$620FlexibilityNo cancel feeOn-time76%
British AirwaysCheapest$518Average$665FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$604Average$682FlexibilityNo cancel feeOn-time69%
SWISSCheapest$621Average$801FlexibilityNo cancel feeOn-time79%
LufthansaCheapest$628Average$932FlexibilityNo cancel feeOn-time76%

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