How popular is this Panama City to San Francisco flight route?

The Panama City Tocumen Intl to San Francisco flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

What are the cheapest airlines flying from Panama City to San Francisco round-trip?

Cheapflights users have booked flights from Panama City to San Francisco round-trip from $566. Other airlines that can offer you cheap pricing are United Airlines, from $610, and American Airlines, from $649. Avianca is priced at 10% lower than the current average price of a flight leaving 3 months from now.

What are the cheapest airlines to fly from Panama City to San Francisco one-way?

The cheapest airlines for a one-way flight from Panama City to San Francisco are Avianca ($312), United Airlines ($565), and Copa Airlines ($687).

What is the cheapest day to fly from Panama City to San Francisco?

Travelers seeking maximum savings on their Panama City to San Francisco flight should consider departing on Friday mornings when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

What are the cheapest flights from Panama City to San Francisco?

The cheapest flight price from Panama City to San Francisco is $586. On average you can expect to pay $1,146. The most popular route, (Panama City Tocumen Intl - San Francisco), can usually be booked for $610.

What are the most popular airlines that fly from Panama City to San Francisco?

When booking a flight from Panama City to San Francisco, you may want to consider flying on Avianca, Copa Airlines or United Airlines as they are the most popular for this route.

What is the cheapest day to fly round-trip from Panama City to San Francisco?

Flying to your destination on a Saturday can be more expensive, but this shouldn’t discourage you from finding affordable options to get to San Francisco. Check prices with Cheapflights to find a great deal for your trip.

How far in advance should I book a flight from Panama City to San Francisco?

Find a great deal and save up to 44% by booking at least 36 days prior to your desired departure date, rather than waiting until the week of travel. According to our data, there are a number of flights available from Panama City to San Francisco within the next two weeks, with the cheapest ticket starting at $546.

What is the cheapest month to fly from Panama City to San Francisco?

Our data shows that May tends to be the cheapest month to fly to San Francisco from Panama City. Users have commonly found prices around $633 for the month, but tickets can be as low as $378. Due to multiple factors, prepare for potentially higher prices in March.

Most accurate provider : When it comes to deals on Panama City-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-San Francisco flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Panama City-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

What airports do I use to fly from Panama City to San Francisco?

If you book a flight from Panama City to San Francisco, you will be flying from Tocumen Intl to San Francisco. Flights to San Francisco (SFO) from Panama City Tocumen Intl (PTY) take 7h 43m for a nonstop flight. There are 2 flights from Tocumen Intl to San Francisco per day from 3 airlines.

Can I find deals for flights from Panama City to San Francisco that include hotel bookings?

Yes. In addition to deals on Panama City to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Panama City to San Francisco?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to San Francisco.

Can I find deals for business class flights from Panama City to San Francisco?

Yes. Cheapflights offers flight deals from Panama City to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$283+ Save on Flights from Panama City to San Francisco

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1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

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The best prices from Panama City Tocumen Intl to San Francisco are usually found in May or June, booked 35 days in advance, depart on a Thursday or Friday and return on a Tuesday

Cheap flight deals from Panama City to San Francisco

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars
Round-trip from	$566 (Cheapflightsfares)
One-way from	$283 (Kiwi.com)
Popular in	March
Cheapest in	May
Average price	$630
Good round-trip deal	$653 or less
Good one-way deal	$586 or less

Provider with most accurate pricing for Panama City Tocumen Intl-San Francisco flight deals.

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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-San Francisco flights.

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From Panama City Tocumen Intl to San Francisco

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One-way flight from Panama City Tocumen Intl to San Francisco

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Highest demand for flights based on searches. 1% potential increase in price ($12 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 0% potential price decrease ($6 potential savings vs. average RT price).

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Average for round-trip flights in February 2025

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Price to beat on a round-trip flight from Panama City Tocumen Intl to San Francisco.

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Price to beat on a one-way flight from Panama City Tocumen Intl to San Francisco.

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Find flight deals from Panama City to San Francisco

Cheapest flights from Panama City to San Francisco
Explore the most affordable flight options available from Panama City to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

Tue 3/113:19 amPTY - SFO

2 stops21h 36mAvianca

Mon 3/3112:05 amSFO - PTY

2 stops19h 05mAvianca

Deal found 2/20

$566

Sat 6/143:15 pmPTY - SFO

Nonstop7h 43mUnited Airlines

Fri 7/1810:55 amSFO - PTY

Nonstop7h 15mUnited Airlines

Deal found 2/19

$610

Thu 10/301:50 pmPTY - SFO

1 stop10h 54mAmerican Airlines

Sat 11/1511:59 pmSFO - PTY

1 stop12h 21mAmerican Airlines

Deal found 2/20

$636

Fri 4/1112:38 pmPTY - SFO

Nonstop7h 52mCopa Airlines

Thu 4/171:40 amSFO - PTY

Nonstop7h 01mCopa Airlines

Deal found 2/20

$663

Tue 3/113:19 amPTY - SFO

3 stops44h 58mMultiple Airlines

Tue 4/19:30 amSFO - PTY

3 stops22h 55mMultiple Airlines

Deal found 2/20

$690

Sat 6/148:05 amPTY - SFO

2 stops17h 15mDelta

Wed 7/163:15 pmSFO - PTY

1 stop19h 39mDelta

Deal found 2/19

$921

Best flights from Panama City to San Francisco
Discover carefully curated flight deals from Panama City to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 20, 2025.

Tue 3/115:25 pmPTY - SFO

2 stops21h 35mAvianca

Mon 3/312:20 pmSFO - PTY

2 stops16h 35mAvianca

Deal found 2/20

$566

Sat 6/143:15 pmPTY - SFO

Nonstop7h 43mUnited Airlines

Tue 7/1511:59 pmSFO - PTY

1 stop16h 38mUnited Airlines

Deal found 2/19

$610

Fri 5/231:20 pmPTY - SFO

1 stop23h 32mAmerican Airlines

Mon 5/261:20 pmSFO - PTY

1 stop20h 55mAmerican Airlines

Deal found 2/20

$649

Fri 4/1112:38 pmPTY - SFO

Nonstop7h 52mCopa Airlines

Thu 4/171:40 amSFO - PTY

Nonstop7h 01mCopa Airlines

Deal found 2/20

$663

Tue 3/113:19 amPTY - SFO

3 stops44h 58mMultiple Airlines

Tue 4/19:30 amSFO - PTY

3 stops22h 55mMultiple Airlines

Deal found 2/20

$690

Sat 6/148:05 amPTY - SFO

2 stops17h 15mDelta

Wed 7/163:15 pmSFO - PTY

1 stop19h 39mDelta

Deal found 2/19

$921

Last-minute flights from Panama City to San Francisco
Discover last-minute flight deals from Panama City to San Francisco. Data last updated February 20, 2025 and is based on user searches.

Tue 2/252:30 pmPTY - SFO

2 stops23h 59mAmerican Airlines

Sun 3/212:32 amSFO - PTY

2 stops12h 18mAmerican Airlines

Deal found 2/19

$1,068

Fri 2/288:05 pmPTY - SFO

1 stop18h 55mAvianca

Sat 3/81:20 pmSFO - PTY

2 stops17h 20mAvianca

Deal found 2/20

$615

Fri 2/288:05 pmPTY - SFO

2 stops30h 10mMultiple Airlines

Fri 3/142:20 pmSFO - PTY

1 stop18h 05mMultiple Airlines

Deal found 2/20

$706

Fri 2/2812:38 pmPTY - SFO

Nonstop7h 55mCopa Airlines

Fri 3/148:20 pmSFO - PTY

Nonstop6h 53mCopa Airlines

Deal found 2/20

$1,028

Tue 3/115:25 pmPTY - SFO

2 stops21h 35mAvianca

Mon 3/312:20 pmSFO - PTY

2 stops16h 35mAvianca

Deal found 2/20

$566

Tue 3/113:19 amPTY - SFO

3 stops44h 58mMultiple Airlines

Tue 4/19:30 amSFO - PTY

3 stops22h 55mMultiple Airlines

Deal found 2/20

$690

Sun 3/165:43 pmPTY - SFO

Nonstop7h 57mCopa Airlines

Sun 3/231:51 amSFO - PTY

Nonstop6h 55mCopa Airlines

Deal found 2/19

$774

Thu 3/271:05 pmPTY - SFO

1 stop12h 04mAmerican Airlines

Sun 3/3011:59 pmSFO - PTY

1 stop12h 41mAmerican Airlines

Deal found 2/19

$678

Thu 3/275:43 pmPTY - SFO

Nonstop7h 57mUnited Airlines

Sun 3/3011:59 pmSFO - PTY

1 stop12h 15mUnited Airlines

Deal found 2/19

$1,921

One-way flights from Panama City to San Francisco
Search for one-way flight options from Panama City to San Francisco. Find affordable one-way fares based on user searches. Data last updated February 20, 2025.

Mon 4/143:25 amPTY - SFO

3 stops21h 43mMultiple Airlines

Deal found 2/20

$283

Sun 3/29:55 pmPTY - SFO

2 stops27h 00mAvianca

Deal found 2/20

$312

Sun 6/293:15 pmPTY - SFO

Nonstop7h 43mUnited Airlines

Deal found 2/20

$565

Mon 4/145:50 pmPTY - SFO

Nonstop7h 50mCopa Airlines

Deal found 2/20

$687

Find flights from Panama City to San Francisco within your budget

Fly from

Fly to

Route

Depart

Return

Price

Panama CitySan Francisco

PTY - SFO

PTYSFO

Panama City Tocumen Intl

Tue 3/11

3:19 am-10:55 pm

2 stops21h 36m

San Francisco

Mon 3/31

12:05 am-9:10 pm

2 stops19h 05m

$566

Panama CitySan Francisco

PTY - SFO

PTYSFO

Panama City Tocumen Intl

Sat 6/14

3:15 pm-8:58 pm

Nonstop7h 43m

San Francisco

Fri 7/18

10:55 am-8:10 pm

Nonstop7h 15m

$610

Panama CitySan Francisco

PTY - SFO

PTYSFO

Panama City Tocumen Intl

Fri 5/23

1:20 pm-10:52 am

1 stop23h 32m

San Francisco

Mon 5/26

1:20 pm-12:15 pm

1 stop20h 55m

$649

Panama CitySan Francisco

PTY - SFO

PTYSFO

Panama City Tocumen Intl

Fri 4/11

12:38 pm-6:30 pm

Nonstop7h 52m

San Francisco

Thu 4/17

1:40 am-10:41 am

Nonstop7h 01m

$663

Panama CitySan Francisco

PTY - SFO

PTYSFO

Panama City Tocumen Intl

Tue 3/11

3:19 am-10:17 pm

3 stops44h 58m

San Francisco

Tue 4/1

9:30 am-10:25 am

3 stops22h 55m

$690

Panama CitySan Francisco

PTY - SFO

PTYSFO

Panama City Tocumen Intl

Sat 6/14

8:05 am-11:20 pm

2 stops17h 15m

San Francisco

Wed 7/16

3:15 pm-12:54 pm

1 stop19h 39m

$921

Panama CitySan Francisco

PTY - SFO

PTYSFO

Panama City Tocumen Intl

Mon 4/14

3:25 am-11:08 pm

3 stops21h 43m

$283

Panama CitySan Francisco

PTY - SFO

PTYSFO

Panama City Tocumen Intl

Sun 3/2

9:55 pm-9:55 pm

2 stops27h 00m

$312

Panama CitySan Francisco

PTY - SFO

PTYSFO

Panama City Tocumen Intl

Sun 6/29

3:15 pm-8:58 pm

Nonstop7h 43m

$565

Panama CitySan Francisco

PTY - SFO

PTYSFO

Panama City Tocumen Intl

Mon 4/14

5:50 pm-11:40 pm

Nonstop7h 50m

$687

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/20

Compare providers for flights from Panama City to San Francisco

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to San Francisco in February.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy1 star	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*3 stars
AranGrant	Price Accuracy3 stars	Trust Score*1 star
Cheapflightsfares	Price Accuracy3 stars	Trust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Panama City-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-San Francisco flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Panama City-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Panama City with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama City to San Francisco

Get recent, data-driven insights about flights from Panama City to San Francisco including ideal travel times, pricing trends, and more.

How far ahead should I book a flight from Panama City to San Francisco?

The price you pay for your flight from Panama City to San Francisco may vary depending on when you book. For the best chance of a lower fare, look to book 35 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Panama City to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Panama City to San Francisco (average of $276). Flying from Panama City to San Francisco in June is currently the most expensive (average of $403). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to SFO?

Unlike in the afternoon, when flights are generally more expensive, you can save up to 35% on flights from Panama City to San Francisco by exploring options for tickets in the evening.

Weekly flight availability from Panama City to San Francisco

The most flights from PTY to SFO are scheduled on a Tuesday (3 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (2 on average).

Rainfall in San Francisco by month

In terms of precipitation, rainfall in San Francisco ranges from 0.0 - 4.4 inches per month. January is typically the wettest month, when rainfall can reach 4.4 in. July is typically the driest time to visit San Francisco when rainfall is around 0.0 in.

Temperature in San Francisco by month

If weather is an important factor for your trip to San Francisco, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

Reviews of airlines servicing San Francisco

To help decide which airline to fly from Panama City to San Francisco, see what other customers have to say about Delta, Copa Airlines and United Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

8,219 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta

8.0

Very good

8,219 reviews

Delta

8.0

Very good

8,219 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Copa Airlines

7.6

Good

1,510 reviews

Delta

8.0

Very good

8,219 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

United Airlines

7.4

Good

8,765 reviews

Delta

8.0

Very good

8,219 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

8,219 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Avianca

6.8

Okay

2,435 reviews

Delta

8.0

Very good

8,219 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

What airports do I use to fly from Panama City to San Francisco?
If you book a flight from Panama City to San Francisco, you will be flying from Tocumen Intl to San Francisco. Flights to San Francisco (SFO) from Panama City Tocumen Intl (PTY) take 7h 43m for a nonstop flight. There are 2 flights from Tocumen Intl to San Francisco per day from 3 airlines.
How popular is this Panama City to San Francisco flight route?
The Panama City Tocumen Intl to San Francisco flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.
What are the cheapest airlines flying from Panama City to San Francisco round-trip?
Cheapflights users have booked flights from Panama City to San Francisco round-trip from $566. Other airlines that can offer you cheap pricing are United Airlines, from $610, and American Airlines, from $649. Avianca is priced at 10% lower than the current average price of a flight leaving 3 months from now.
What are the cheapest airlines to fly from Panama City to San Francisco one-way?
The cheapest airlines for a one-way flight from Panama City to San Francisco are Avianca ($312), United Airlines ($565), and Copa Airlines ($687).
What are the cheapest flights from Panama City to San Francisco?
The cheapest flight price from Panama City to San Francisco is $586. On average you can expect to pay $1,146. The most popular route, (Panama City Tocumen Intl - San Francisco), can usually be booked for $610.
Can I find deals for flights from Panama City to San Francisco that include hotel bookings?
Yes. In addition to deals on Panama City to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Panama City to San Francisco?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to San Francisco.
Can I find deals for business class flights from Panama City to San Francisco?
Yes. Cheapflights offers flight deals from Panama City to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Panama City to San Francisco?
Currently, January is the cheapest month in which you can book a flight from Panama City to San Francisco (average of $276). Flying from Panama City to San Francisco in June is currently the most expensive (average of $403). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Panama City to San Francisco

Airline	Cheapest	Average	Flexibility	On-time
Avianca	Cheapest$410	Average$625	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$546	Average$843	FlexibilityNo cancel fee	On-time69%
Copa Airlines	Cheapest$554	Average$630	FlexibilityNo cancel fee	On-time70%

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$283+ Cheap flights from Panama City (PTY) to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/14. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Panama City to San Francisco with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

The best prices from Panama City Tocumen Intl to San Francisco are usually found in May or June, booked 35 days in advance, depart on a Thursday or Friday and return on a Tuesday

Cheap flight deals from Panama City to San Francisco

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Find flight deals from Panama City to San Francisco

Cheapest flights from Panama City to San FranciscoExplore the most affordable flight options available from Panama City to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

Explore the most affordable flight options available from Panama City to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

Find flights from Panama City to San Francisco within your budget

Compare providers for flights from Panama City to San Francisco

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to San Francisco in February.

Best time to book a flight from Panama City to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Panama City with our price prediction graph.

Travel insights for flights from Panama City to San Francisco

Get recent, data-driven insights about flights from Panama City to San Francisco including ideal travel times, pricing trends, and more.

How far ahead should I book a flight from Panama City to San Francisco?

Use this chart to determine the optimal time to book a round-trip flight from Panama City to San Francisco. Price data was last updated on February 14, 2025.

What is the cheapest month to book a flight from Panama City to San Francisco?

What is the cheapest time of day to fly from PTY to SFO?

Find hourly flight availability from Panama City to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 20, 2025.

Weekly flight availability from Panama City to San Francisco

Rainfall in San Francisco by month

Plan your trip to San Francisco by taking into account the average rainfall totals by month.

Temperature in San Francisco by month

Plan your trip to San Francisco by taking into account the average temperature totals by month.

Reviews of airlines servicing San Francisco

Related info for your journey

Find useful and relevant information for your journey from Panama City to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airports do I use to fly from Panama City to San Francisco?

How popular is this Panama City to San Francisco flight route?

What are the cheapest airlines flying from Panama City to San Francisco round-trip?

What are the cheapest airlines to fly from Panama City to San Francisco one-way?

What are the cheapest flights from Panama City to San Francisco?

Can I find deals for flights from Panama City to San Francisco that include hotel bookings?

How can I find direct flights from Panama City to San Francisco?

Can I find deals for business class flights from Panama City to San Francisco?

What is the cheapest month to book a flight from Panama City to San Francisco?

Traveling to a place near Panama City?

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Alternative routes for Panama City to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Panama City to San Francisco

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Cheapest flights from Panama City to San Francisco
Explore the most affordable flight options available from Panama City to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.