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$284+ Cheap flights from Panama to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/31. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SFO
feb. 4 — feb. 111
mar. 2/4
mar. 2/11
1 adult, Economy
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Cheap flight deals from Panama to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Panama (PA0) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated enero 30, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$581
(Priceline)

One-way from

$284
(Kiwi.com)

Popular in

January

Cheapest in

May

Average price

$726

Good round-trip deal

$656 or less

Good one-way deal

$1,073 or less
Provider with most accurate pricing for Panama City Tocumen Intl-San Francisco flight deals.
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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-San Francisco flights.
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From Panama to San Francisco
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One-way flight from Panama to San Francisco
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Highest demand for flights based on searches. 2% potential increase in price ($18 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in January 2025
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Price to beat on a round-trip flight from Panama to San Francisco.
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Price to beat on a one-way flight from Panama to San Francisco.
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Find flight deals from Panama to San Francisco

Cheapest flights from Panama to San Francisco
Explore the most affordable flight options available from Panama to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on enero 30, 2025.

This Priceline deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 2/1211:20 amPTY - SFO
2 stops27h 40mAvianca
mar. 3/182:20 pmSFO - PTY
2 stops22h 20mAvianca
Deal found 1/30$581
This Copa Airlines deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 6/185:50 pmPTY - SFO
Nonstop7h 50mCopa Airlines
mar. 7/151:37 amSFO - PTY
Nonstop7h 04mCopa Airlines
Deal found 1/30$632
This Kiwi.com deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 3/38:05 pmPTY - SFO
2 stops30h 10mMultiple Airlines
jue. 3/273:30 pmSFO - PTY
1 stop13h 07mMultiple Airlines
Deal found 1/30$636
This American Airlines deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/221:20 pmPTY - SFO
1 stop11h 39mAmerican Airlines
mar. 5/271:20 pmSFO - PTY
1 stop21h 00mAmerican Airlines
Deal found 1/30$642
This United Airlines deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 3/34:40 pmPTY - SFO
1 stop18h 01mUnited Airlines
jue. 3/276:40 pmSFO - PTY
1 stop21h 58mUnited Airlines
Deal found 1/30$669

Find flights from Panama to San Francisco within your budget

Customize your flight search to find flights from Panama to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 30, 2025.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

Panama CitySan Francisco

PTY - SFO

PTYSFO

Panama City Tocumen Intl

mié. 2/12

11:20 am-12:00 pm

2 stops27h 40m

San Francisco

mar. 3/18

2:20 pm-2:40 pm

2 stops22h 20m

$581

Panama CitySan Francisco

PTY - SFO

PTYSFO

Panama City Tocumen Intl

mié. 6/18

5:50 pm-11:40 pm

Nonstop7h 50m

San Francisco

mar. 7/15

1:37 am-10:41 am

Nonstop7h 04m

$632

Panama CitySan Francisco

PTY - SFO

PTYSFO

Panama City Tocumen Intl

lun. 3/3

8:05 pm-11:15 pm

2 stops30h 10m

San Francisco

jue. 3/27

3:30 pm-6:37 am

1 stop13h 07m

$636

Panama CitySan Francisco

PTY - SFO

PTYSFO

Panama City Tocumen Intl

jue. 5/22

1:20 pm-10:59 pm

1 stop11h 39m

San Francisco

mar. 5/27

1:20 pm-12:20 pm

1 stop21h 00m

$642

Panama CitySan Francisco

PTY - SFO

PTYSFO

Panama City Tocumen Intl

lun. 3/3

4:40 pm-7:41 am

1 stop18h 01m

San Francisco

jue. 3/27

6:40 pm-6:38 pm

1 stop21h 58m

$669

Panama CitySan Francisco

PTY - SFO

PTYSFO

Panama City Tocumen Intl

lun. 3/31

8:10 pm-11:08 pm

2 stops28h 58m

$284

Panama CitySan Francisco

PTY - SFO

PTYSFO

Panama City Tocumen Intl

mar. 4/1

9:50 am-11:55 pm

2 stops16h 05m

$331

Panama CitySan Francisco

PTY - SFO

PTYSFO

Panama City Tocumen Intl

dom. 6/29

3:15 pm-8:58 pm

Nonstop7h 43m

$587

Panama CitySan Francisco

PTY - SFO

PTYSFO

Panama City Tocumen Intl

sáb. 3/1

6:27 pm-11:24 pm

Nonstop7h 57m

$815

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/30

Best time to book a flight from Panama to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama to San Francisco

Get recent, data-driven insights about flights from Panama to San Francisco including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Panama to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Panama to San Francisco (average of $276). Flying from Panama to San Francisco in June is currently the most expensive (average of $405). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PA to SFO?

Find hourly flight availability from Panama to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated enero 30, 2025.

A simple way to save on the total cost of your ticket is to fly from Panama to San Francisco in the morning. If you’re flexible enough to do this you can expect to save up to 5% on your trip compared to booking a flight at noon.

Weekly flight availability from Panama to San Francisco

Explore weekly flight availability from Panama to San Francisco. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated enero 30, 2025.

The most flights from PA0 to SFO are scheduled on a Tuesday (3 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (2 on average).

Rainfall in San Francisco by month

Plan your trip to San Francisco by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in San Francisco ranges from 0.0 - 4.4 inches per month. January is typically the wettest month, when rainfall can reach 4.4 in. July is typically the driest time to visit San Francisco when rainfall is around 0.0 in.

Temperature in San Francisco by month

Plan your trip to San Francisco by taking into account the average temperature totals by month.

If weather is an important factor for your trip to San Francisco, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated enero 30, 2025.
Read reviews from past customers who have flown Copa Airlines, United Airlines and American Airlines from Panama to San Francisco. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,617 reviews

Food

6.9

Boarding

7.9

Overall

7.6

Crew

8.1

Comfort

7.5

Entertainment

6.9

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

Copa Airlines
7.6
Good
1,617 reviews
Copa Airlines
7.6
Good
1,617 reviews

Food

6.9

Boarding

7.9

Overall

7.6

Crew

8.1

Comfort

7.5

Entertainment

6.9

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

United Airlines
7.4
Good
8,913 reviews
Copa Airlines
7.6
Good
1,617 reviews

Food

6.9

Boarding

7.9

Overall

7.6

Crew

8.1

Comfort

7.5

Entertainment

6.9

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

American Airlines
7.2
Good
10,000 reviews
Copa Airlines
7.6
Good
1,617 reviews

Food

6.9

Boarding

7.9

Overall

7.6

Crew

8.1

Comfort

7.5

Entertainment

6.9

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

Avianca
6.9
Okay
2,534 reviews
Copa Airlines
7.6
Good
1,617 reviews

Food

6.9

Boarding

7.9

Overall

7.6

Crew

8.1

Comfort

7.5

Entertainment

6.9

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

Related info for your journey

Find useful and relevant information for your journey from Panama to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Francisco from Panama?

    If you book a flight to San Francisco from Panama, you will be flying to San Francisco, which is the city’s only airport. San Francisco (SFO) is located 11.8 mi from the center of San Francisco.

  • How popular is this Panama to San Francisco flight route?

    The Panama to San Francisco flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines to fly from Panama to San Francisco one-way?

    One-way options have recently been found by users for as low as $331 on Avianca. Other airlines that offer cheap prices include United Airlines from $587 and Copa Airlines from $815 one-way.

  • What are the cheapest flights from Panama to San Francisco?

    The cheapest flight price from Panama to San Francisco is $642. On average you can expect to pay $930. The most popular route, (Panama City Tocumen Intl - San Francisco), can usually be booked for $654.

  • Can I find deals for flights from Panama to San Francisco that include hotel bookings?

    Yes. In addition to deals on Panama to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to San Francisco.

  • Can I find deals for business class flights from Panama to San Francisco?

    Yes. Cheapflights offers flight deals from Panama to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to San Francisco?

    Currently, January is the cheapest month in which you can book a flight from Panama to San Francisco (average of $276). Flying from Panama to San Francisco in June is currently the most expensive (average of $405). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama?

Book flights to Panama if you plan to visit one of these locations
Roseville
Mountain View
Turlock
Santa Cruz
Fairfield
Manteca
Sausalito
Watsonville
Hayward
Richmond
Hollister
South San Francisco
Antioch
Milpitas
Elk Grove
Vallejo
Newark
Alameda
Campbell
Pacific Grove

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Alternative routes for Panama to San Francisco

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Top 3 airlines flying from Panama to San Francisco

Discover the top 3 airlines that operate flights from Panama to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$367Average$634FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$546Average$842FlexibilityNo cancel feeOn-time69%
Copa AirlinesCheapest$554Average$779FlexibilityNo cancel feeOn-time70%
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