HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
San Francisco

$278+ Cheap flights from Panama to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/2. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SFO
Apr 22 — Apr 291
Tue 4/22
Tue 4/29
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Panama to San Francisco with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Panama to San Francisco

Keep the following information in mind while searching for Panama to San Francisco flight deals. Data was last updated April 17, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$493
(Avianca)

One-way from

$278
(Priceline)

Popular in

March

Cheapest in

May

Average price

$665

Good round-trip deal

$514 or less

Good one-way deal

$565 or less
Provider with most accurate pricing for Panama City Tocumen Intl-San Francisco flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City Tocumen Intl-San Francisco flights.
Search Deals
From Panama to San Francisco
Search Deals
One-way flight from Panama to San Francisco
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($24 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 0% potential price decrease ($4 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2025
Search Deals
Price to beat on a round-trip flight from Panama to San Francisco.
Search Deals
Price to beat on a one-way flight from Panama to San Francisco.
Search Deals

Find flight deals from Panama to San Francisco

Cheapest flights from Panama to San Francisco
Explore the most affordable flight options available from Panama to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.

This Avianca deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/283:40 pmPTY - SFO
1 stop9h 05mAvianca
Sat 8/302:30 amSFO - PTY
1 stop10h 15mAvianca
Deal found 4/17$493
This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/283:15 pmPTY - SFO
Nonstop7h 35mUnited Airlines
Sat 8/3010:55 amSFO - PTY
Nonstop7h 15mUnited Airlines
Deal found 4/16$514
This Copa Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/285:50 pmPTY - SFO
Nonstop7h 50mCopa Airlines
Fri 8/291:28 amSFO - PTY
Nonstop7h 13mCopa Airlines
Deal found 4/16$530
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/81:50 pmPTY - SFO
2 stops20h 46mAmerican Airlines
Thu 6/266:47 pmSFO - PTY
2 stops17h 38mAmerican Airlines
Deal found 4/17$640
This Mytrip deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/81:30 pmPTY - SFO
3 stops47h 38mMultiple Airlines
Wed 6/2512:05 amSFO - PTY
2 stops14h 25mMultiple Airlines
Deal found 4/17$809

Cheapflights Fare Finder

Customize your flight search to find flights from Panama to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
Use the filters below to find and compare flights from Panama to San Francisco that are best for you.

Fly from

Panama

Fly to

San Francisco

Route

Depart

Return

Price

Panama CitySan Francisco

PTY - SFO

PTYSFO

Panama City Tocumen Intl

Thu 8/28

3:40 pm-10:45 pm

1 stop9h 05m

San Francisco

Sat 8/30

2:30 am-2:45 pm

1 stop10h 15m

$493

Panama CitySan Francisco

PTY - SFO

PTYSFO

Panama City Tocumen Intl

Thu 8/28

3:15 pm-8:50 pm

Nonstop7h 35m

San Francisco

Sat 8/30

10:55 am-8:10 pm

Nonstop7h 15m

$514

Panama CitySan Francisco

PTY - SFO

PTYSFO

Panama City Tocumen Intl

Thu 8/28

5:50 pm-11:40 pm

Nonstop7h 50m

San Francisco

Fri 8/29

1:28 am-10:41 am

Nonstop7h 13m

$530

Panama CitySan Francisco

PTY - SFO

PTYSFO

Panama City Tocumen Intl

Sun 6/8

1:50 pm-8:36 am

2 stops20h 46m

San Francisco

Thu 6/26

6:47 pm-2:25 pm

2 stops17h 38m

$640

Panama CitySan Francisco

PTY - SFO

PTYSFO

Panama City Tocumen Intl

Sun 6/8

1:30 pm-11:08 am

3 stops47h 38m

San Francisco

Wed 6/25

12:05 am-4:30 pm

2 stops14h 25m

$809

Panama CitySan Francisco

PTY - SFO

PTYSFO

Panama City Tocumen Intl

Mon 6/2

3:25 am-11:55 pm

2 stops22h 30m

$278

Panama CitySan Francisco

PTY - SFO

PTYSFO

Panama City Tocumen Intl

Tue 5/20

5:25 pm-11:53 pm

3 stops32h 28m

$294

Panama CitySan Francisco

PTY - SFO

PTYSFO

Panama City Tocumen Intl

Wed 7/2

3:15 pm-8:58 pm

Nonstop7h 43m

$469

Panama CitySan Francisco

PTY - SFO

PTYSFO

Panama City Tocumen Intl

Tue 6/3

5:50 pm-11:40 pm

Nonstop7h 50m

$810

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/16

Best time to book a flight from Panama to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to San Francisco

What is the cheapest month to book a flight from Panama to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Panama to San Francisco (average of $276). Flying from Panama to San Francisco in June is currently the most expensive (average of $393). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PA to SFO?

Find hourly flight availability from Panama to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 17, 2025.

A simple way to save on the total cost of your ticket is to fly from Panama to San Francisco in the morning. If you’re flexible enough to do this you can expect to save up to 6% on your trip compared to booking a flight at noon.

Weekly flight availability from Panama to San Francisco

Explore weekly flight availability from Panama to San Francisco. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated April 17, 2025.

The most flights from PA0 to SFO are scheduled on a Tuesday (3 on average). You will have fewer flight options on Sunday, which is when the least amount of flights are scheduled (1 on average).

Rainfall in San Francisco by month

Plan your trip to San Francisco by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in San Francisco ranges from 0.0 - 4.4 inches per month. January is typically the wettest month, when rainfall can reach 4.4 in. July is typically the driest time to visit San Francisco when rainfall is around 0.0 in.

Temperature in San Francisco by month

Plan your trip to San Francisco by taking into account the average temperature totals by month.

If weather is an important factor for your trip to San Francisco, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated April 17, 2025.
Read reviews from past customers who have flown Copa Airlines, United Airlines and American Airlines from Panama to San Francisco. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,409 reviews

Entertainment

6.8

Comfort

7.4

Crew

8.1

Overall

7.6

Food

6.8

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Anonymous,Mar 2025

PTY - JFK

There was no chance for me to choose a seat even if I were willing to pay extra for it when I was doing the check-in on line. My seats were the last row on the plane and they didn't have enough food to give me. I had to eat what was left after everybody else had their choice of food. This is unacceptable. Everyone should have a choice. I paid money just like everybody else. Never had this happened on any other airlines even if my seats were last row on the plane.
Copa Airlines
7.6
Good
1,409 reviews
Copa Airlines
7.6
Good
1,409 reviews

Entertainment

6.8

Comfort

7.4

Crew

8.1

Overall

7.6

Food

6.8

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Anonymous,Mar 2025

PTY - JFK

There was no chance for me to choose a seat even if I were willing to pay extra for it when I was doing the check-in on line. My seats were the last row on the plane and they didn't have enough food to give me. I had to eat what was left after everybody else had their choice of food. This is unacceptable. Everyone should have a choice. I paid money just like everybody else. Never had this happened on any other airlines even if my seats were last row on the plane.
United Airlines
7.4
Good
8,667 reviews
Copa Airlines
7.6
Good
1,409 reviews

Entertainment

6.8

Comfort

7.4

Crew

8.1

Overall

7.6

Food

6.8

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Anonymous,Mar 2025

PTY - JFK

There was no chance for me to choose a seat even if I were willing to pay extra for it when I was doing the check-in on line. My seats were the last row on the plane and they didn't have enough food to give me. I had to eat what was left after everybody else had their choice of food. This is unacceptable. Everyone should have a choice. I paid money just like everybody else. Never had this happened on any other airlines even if my seats were last row on the plane.
American Airlines
7.2
Good
10,000 reviews
Copa Airlines
7.6
Good
1,409 reviews

Entertainment

6.8

Comfort

7.4

Crew

8.1

Overall

7.6

Food

6.8

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Anonymous,Mar 2025

PTY - JFK

There was no chance for me to choose a seat even if I were willing to pay extra for it when I was doing the check-in on line. My seats were the last row on the plane and they didn't have enough food to give me. I had to eat what was left after everybody else had their choice of food. This is unacceptable. Everyone should have a choice. I paid money just like everybody else. Never had this happened on any other airlines even if my seats were last row on the plane.
Avianca
6.7
Okay
2,316 reviews
Copa Airlines
7.6
Good
1,409 reviews

Entertainment

6.8

Comfort

7.4

Crew

8.1

Overall

7.6

Food

6.8

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Anonymous,Mar 2025

PTY - JFK

There was no chance for me to choose a seat even if I were willing to pay extra for it when I was doing the check-in on line. My seats were the last row on the plane and they didn't have enough food to give me. I had to eat what was left after everybody else had their choice of food. This is unacceptable. Everyone should have a choice. I paid money just like everybody else. Never had this happened on any other airlines even if my seats were last row on the plane.

Related info for your journey

Find useful and relevant information for your journey from Panama to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Francisco from Panama?

    If you book a flight to San Francisco from Panama, you will be flying to San Francisco, which is the city’s only airport. San Francisco (SFO) is located 11.8 mi from the center of San Francisco.

  • How popular is this Panama to San Francisco flight route?

    The Panama to San Francisco flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines to fly from Panama to San Francisco one-way?

    One-way options have recently been found by users for as low as $278 on Avianca. Other airlines that offer cheap prices include United Airlines from $469 and Copa Airlines from $810 one-way.

  • What are the cheapest flights from Panama to San Francisco?

    The cheapest flight price from Panama to San Francisco is $335. On average you can expect to pay $692. The most popular route, (Panama City Tocumen Intl - San Francisco), can usually be booked for $489.

  • Can I find deals for flights from Panama to San Francisco that include hotel bookings?

    Yes. In addition to deals on Panama to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to San Francisco.

  • Can I find deals for business class flights from Panama to San Francisco?

    Yes. Cheapflights offers flight deals from Panama to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to San Francisco?

    Currently, January is the cheapest month in which you can book a flight from Panama to San Francisco (average of $276). Flying from Panama to San Francisco in June is currently the most expensive (average of $393). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama?

Book flights to Panama if you plan to visit one of these locations
Roseville
Mountain View
Santa Cruz
Turlock
South San Francisco
Fairfield
Manteca
Sausalito
Richmond
Watsonville
Hollister
Milpitas
Antioch
Vallejo
Newark
Hayward
Alameda
Sunnyvale
Livermore
Campbell

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Panama to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.
Guatemala City to Los Angeles flights
San José to Los Angeles flights
San Salvador to Los Angeles flights
San José to Las Vegas flights
Panama City to Los Angeles flights
San José to San Francisco flights
Guatemala City to Ontario flights
San Salvador to Ontario flights
Guatemala City to Las Vegas flights
Guatemala City to San Francisco flights
Panama City to San Francisco flights
San Salvador to San Francisco flights
San José to Ontario flights
San Salvador to Las Vegas flights
San Pedro Sula to Los Angeles flights
Managua to San Francisco flights
Managua to Los Angeles flights
San Pedro Sula to Las Vegas flights
Panama City to Las Vegas flights
Philip S.W.Goldson to Los Angeles flights
San José to Burbank flights
Managua to Ontario flights
Panama City to Ontario flights
Liberia to Los Angeles flights
San Salvador to Oakland flights
San Salvador to Burbank flights
Guatemala City to Santa Ana flights
San José to San Jose flights
San José to San Diego flights
San Pedro Sula to San Francisco flights
San José to Oakland flights
Guatemala City to Reno flights
Guatemala City to San Diego flights
Panama City to San Diego flights
San José to Sacramento flights
Philip S.W.Goldson to Ontario flights
San José to Reno flights
Guatemala City to Oakland flights
Liberia to San Francisco flights
San Salvador to San Jose flights
Guatemala City to San Jose flights
San José to Santa Ana flights
Managua to Las Vegas flights
Liberia to Las Vegas flights
Guatemala City to Sacramento flights
San Salvador to Santa Ana flights
Philip S.W.Goldson to San Francisco flights
Liberia to Ontario flights

Top 3 airlines flying from Panama to San Francisco

Discover the top 3 airlines that operate flights from Panama to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$341Average$616FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$514Average$631FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$610Average$842FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.