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$75+ Cheap flights from Missouri to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/8. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SFO
Feb 25 — Mar 41
Tue 2/25
Tue 3/4
1 adult, Economy
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Cheap flight deals from Missouri to San Francisco

Keep the following information in mind while searching for Missouri to San Francisco flight deals. Data was last updated February 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$220
(CheapOair)

One-way from

$75
(Cheapflightsfares)

Good round-trip deal

$407 or less

Good one-way deal

$182 or less
Provider with most accurate pricing for Kansas City Downtown-San Francisco flight deals.
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From Missouri to San Francisco
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One-way flight from Missouri to San Francisco
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Price to beat on a round-trip flight from Missouri to San Francisco.
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Price to beat on a one-way flight from Missouri to San Francisco.
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Find flight deals from Missouri to San Francisco

Cheapest flights from Missouri to San Francisco
Explore the most affordable flight options available from Missouri to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

This CheapOair deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/228:35 pmMCI - SFO
1 stop6h 08mFrontier
Thu 3/278:00 pmSFO - MCI
1 stop21h 35mFrontier
Deal found 2/19$220
This Orbitz deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/228:35 pmMCI - SFO
1 stop6h 08mMultiple Airlines
Wed 3/267:35 amSFO - MCI
2 stops14h 24mMultiple Airlines
Deal found 2/18$232
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/206:14 pmMCI - SFO
1 stop7h 45mDelta
Thu 3/276:10 amSFO - MCI
1 stop6h 54mDelta
Deal found 2/19$237
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/66:35 amSTL - SFO
1 stop12h 40mMultiple Airlines
Sun 4/136:00 amSFO - STL
1 stop25h 06mMultiple Airlines
Deal found 2/19$239
This CheapOair deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/66:45 pmSTL - SFO
1 stop29h 14mFrontier
Sun 3/98:10 pmSFO - STL
1 stop11h 06mFrontier
Deal found 2/19$240
This Alaska Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/207:00 amMCI - SFO
1 stop18h 44mAlaska Airlines
Wed 3/267:35 amSFO - MCI
2 stops14h 24mAlaska Airlines
Deal found 2/19$283
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/75:27 amSGF - SFO
1 stop7h 56mAmerican Airlines
Tue 5/1311:39 pmSFO - SGF
1 stop7h 08mAmerican Airlines
Deal found 2/20$289
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/195:50 amSGF - SFO
1 stop5h 42mUnited Airlines
Wed 9/245:00 amSFO - SGF
1 stop6h 40mUnited Airlines
Deal found 2/19$290
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/15:54 pmSTL - SFO
Nonstop4h 28mUnited Airlines
Tue 4/810:45 amSFO - STL
Nonstop4h 07mUnited Airlines
Deal found 2/19$297
This Alaska Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/83:11 pmSTL - SFO
1 stop8h 58mAlaska Airlines
Tue 4/298:30 amSFO - STL
2 stops13h 29mAlaska Airlines
Deal found 2/20$315
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/187:40 amSTL - SFO
1 stop6h 59mDelta
Wed 4/25:55 amSFO - STL
1 stop8h 53mDelta
Deal found 2/20$317
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/165:00 amSTL - SFO
1 stop7h 39mAmerican Airlines
Sat 5/176:00 amSFO - STL
1 stop7h 14mAmerican Airlines
Deal found 2/19$333

Find flights from Missouri to San Francisco within your budget

Customize your flight search to find flights from Missouri to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.

Fly from

Missouri

Fly to

San Francisco

Route

Depart

Return

Price

Kansas CitySan Francisco

MCI - SFO

MCISFO

Kansas City

Sat 3/22

8:35 pm-12:43 am

1 stop6h 08m

San Francisco

Thu 3/27

8:00 pm-7:35 pm

1 stop21h 35m

$220

Kansas CitySan Francisco

MCI - SFO

MCISFO

Kansas City

Sat 3/22

8:35 pm-12:43 am

1 stop6h 08m

San Francisco

Wed 3/26

7:35 am-11:59 pm

2 stops14h 24m

$232

Kansas CitySan Francisco

MCI - SFO

MCISFO

Kansas City

Thu 3/20

4:08 pm-8:02 pm

1 stop5h 54m

San Francisco

Wed 3/26

6:10 am-3:04 pm

1 stop6h 54m

$237

St. LouisSan Francisco

STL - SFO

STLSFO

Lambert-St Louis

Sun 4/6

6:35 am-5:15 pm

1 stop12h 40m

San Francisco

Sun 4/13

6:00 am-9:06 am

1 stop25h 06m

$239

St. LouisSan Francisco

STL - SFO

STLSFO

Lambert-St Louis

Thu 3/6

6:45 pm-9:59 pm

1 stop29h 14m

San Francisco

Sun 3/9

8:10 pm-9:16 am

1 stop11h 06m

$240

Kansas CitySan Francisco

MCI - SFO

MCISFO

Kansas City

Thu 3/20

7:00 am-11:44 pm

1 stop18h 44m

San Francisco

Wed 3/26

7:35 am-11:59 pm

2 stops14h 24m

$283

SpringfieldSan Francisco

SGF - SFO

SGFSFO

Springfield-Branson

Wed 5/7

5:27 am-11:23 am

1 stop7h 56m

San Francisco

Tue 5/13

11:39 pm-8:47 am

1 stop7h 08m

$289

St. LouisSan Francisco

STL - SFO

STLSFO

Lambert-St Louis

Tue 4/1

5:54 pm-8:22 pm

Nonstop4h 28m

San Francisco

Tue 4/8

10:45 am-4:52 pm

Nonstop4h 07m

$297

St. LouisSan Francisco

STL - SFO

STLSFO

Lambert-St Louis

Tue 4/8

3:11 pm-10:09 pm

1 stop8h 58m

San Francisco

Tue 4/29

8:30 am-11:59 pm

2 stops13h 29m

$315

St. LouisSan Francisco

STL - SFO

STLSFO

Lambert-St Louis

Tue 3/18

7:40 am-12:39 pm

1 stop6h 59m

San Francisco

Wed 4/2

5:55 am-4:48 pm

1 stop8h 53m

$317

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/20

Showing 1-10 of 38 results
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Best time to book a flight from Missouri to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Missouri to San Francisco

Get recent, data-driven insights about flights from Missouri to San Francisco including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Missouri to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Missouri to San Francisco (average of $276). Flying from Missouri to San Francisco in June is currently the most expensive (average of $403). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to SFO?

Find hourly flight availability from Missouri to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 20, 2025.

When flying from Missouri to San Francisco, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Weekly flight availability from Missouri to San Francisco

Explore weekly flight availability from Missouri to San Francisco. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated February 20, 2025.

The most flights from USMO to SFO are scheduled on a Monday (4 on average). You will have fewer flight options on Sunday, which is when the least amount of flights are scheduled (2 on average).

Rainfall in San Francisco by month

Plan your trip to San Francisco by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in San Francisco ranges from 0.0 - 4.4 inches per month. January is typically the wettest month, when rainfall can reach 4.4 in. July is typically the driest time to visit San Francisco when rainfall is around 0.0 in.

Temperature in San Francisco by month

Plan your trip to San Francisco by taking into account the average temperature totals by month.

If weather is an important factor for your trip to San Francisco, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated February 20, 2025.
See what other customers who have flown with Southwest, Alaska Airlines and Delta from Missouri to San Francisco have to say. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,411 reviews

Boarding

8.2

Entertainment

7.6

Comfort

8.1

Crew

8.7

Food

7.1

Overall

8.1

Reviews

1 / 20

6.0
Good

Lauren,Dec 2024

MCI - DCA

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Southwest
8.1
Very good
4,411 reviews
Southwest
8.1
Very good
4,411 reviews

Boarding

8.2

Entertainment

7.6

Comfort

8.1

Crew

8.7

Food

7.1

Overall

8.1

Reviews

1 / 20

6.0
Good

Lauren,Dec 2024

MCI - DCA

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Alaska Airlines
8.0
Very good
9,697 reviews
Southwest
8.1
Very good
4,411 reviews

Boarding

8.2

Entertainment

7.6

Comfort

8.1

Crew

8.7

Food

7.1

Overall

8.1

Reviews

1 / 20

6.0
Good

Lauren,Dec 2024

MCI - DCA

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Delta
8.0
Very good
8,219 reviews
Southwest
8.1
Very good
4,411 reviews

Boarding

8.2

Entertainment

7.6

Comfort

8.1

Crew

8.7

Food

7.1

Overall

8.1

Reviews

1 / 20

6.0
Good

Lauren,Dec 2024

MCI - DCA

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Hawaiian Airlines
7.9
Good
2,317 reviews
Southwest
8.1
Very good
4,411 reviews

Boarding

8.2

Entertainment

7.6

Comfort

8.1

Crew

8.7

Food

7.1

Overall

8.1

Reviews

1 / 20

6.0
Good

Lauren,Dec 2024

MCI - DCA

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

United Airlines
7.4
Good
8,765 reviews
Southwest
8.1
Very good
4,411 reviews

Boarding

8.2

Entertainment

7.6

Comfort

8.1

Crew

8.7

Food

7.1

Overall

8.1

Reviews

1 / 20

6.0
Good

Lauren,Dec 2024

MCI - DCA

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Related info for your journey

Find useful and relevant information for your journey from Missouri to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Francisco from Missouri?

    San Francisco (SFO) is the airport you will fly into if you book a flight from Missouri to San Francisco. It is only a 11.8 mi journey from San Francisco (SFO) to San Francisco’s city center.

  • How popular is this Missouri to San Francisco flight route?

    Flights from Missouri to San Francisco have been viewed 8 times in the past calendar month.

  • What are the cheapest airlines to fly from Missouri to San Francisco one-way?

    The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $75. However, be on the lookout for offers from Alaska Airlines and Delta, as they are both options that can get you from Missouri to San Francisco for a low price.

  • What are the most popular routes from Missouri to San Francisco?

    The most popular flight routes from Missouri to San Francisco are Kansas City - San Francisco, Lambert-St Louis - San Francisco and Springfield-Branson - San Francisco.

  • What are the most reliable airlines from Missouri to San Francisco?

    Before booking your flight to San Francisco from Missouri, check out the most reliable airlines to get you to your destination on time: Asiana Airlines (84%), Air New Zealand (84%), United Airlines( 82%).

  • What are the cheapest flights from Missouri to San Francisco?

    On average you can expect to pay $680 for a flight from Missouri to San Francisco. The cheapest flight overall is $113 while the most popular route, (Kansas City - San Francisco) is currently priced at $194.

  • Can I find deals for flights from Missouri to San Francisco that include hotel bookings?

    Yes. In addition to deals on Missouri to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to San Francisco.

  • Can I find deals for business class flights from Missouri to San Francisco?

    Yes. Cheapflights offers flight deals from Missouri to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to San Francisco?

    Currently, January is the cheapest month in which you can book a flight from Missouri to San Francisco (average of $276). Flying from Missouri to San Francisco in June is currently the most expensive (average of $403). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Missouri?

Book flights to Missouri if you plan to visit one of these locations
Roseville
Mountain View
Turlock
Santa Cruz
Fairfield
Manteca
Sausalito
Watsonville
Hayward
Richmond
Hollister
South San Francisco
Antioch
Milpitas
Vallejo
Newark
Alameda
Campbell
Pacific Grove
Sunnyvale

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Alternative routes for Missouri to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Missouri to San Francisco

Discover the top 5 airlines that operate flights from Missouri to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$99Average$198FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$215Average$439FlexibilityNo cancel feeOn-time71%
DeltaCheapest$216Average$341FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$228Average$437FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$295Average$423FlexibilityNo cancel feeOn-time63%
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