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$115+ Cheap flights from Missouri to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/19. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SFO
Apr 2 — Apr 91
Wed 4/2
Wed 4/9
1 adult, Economy
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Cheap flight deals from Missouri to San Francisco

Keep the following information in mind while searching for Missouri to San Francisco flight deals. Data was last updated March 28, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$237
(Delta)

One-way from

$115
(American Airlines)

Good round-trip deal

$497 or less

Good one-way deal

$183 or less
Provider with most accurate pricing for Kansas City Downtown-San Francisco flight deals.
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Provider most trusted by Cheapflights users for Kansas City Downtown-San Francisco flights.
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From Missouri to San Francisco
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One-way flight from Missouri to San Francisco
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Price to beat on a round-trip flight from Missouri to San Francisco.
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Price to beat on a one-way flight from Missouri to San Francisco.
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Find flight deals from Missouri to San Francisco

Cheapest flights from Missouri to San Francisco
Explore the most affordable flight options available from Missouri to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 28, 2025.

This Delta deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/26:20 pmMCI - SFO
1 stop6h 56mDelta
Mon 10/612:40 amSFO - MCI
1 stop5h 44mDelta
Deal found 3/28$237
This Frontier deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/266:58 pmSTL - SFO
1 stop7h 35mFrontier
Sat 5/39:59 pmSFO - STL
1 stop24h 07mFrontier
Deal found 3/27$239
This CheapOair deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/58:51 pmMCI - SFO
1 stop19h 53mFrontier
Thu 5/84:17 pmSFO - MCI
1 stop25h 34mFrontier
Deal found 3/27$240
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/711:33 amSGF - SFO
1 stop10h 08mAmerican Airlines
Sat 5/1012:21 amSFO - SGF
1 stop8h 30mAmerican Airlines
Deal found 3/27$289
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/285:00 amSTL - SFO
1 stop10h 19mAmerican Airlines
Sat 5/313:50 pmSFO - STL
1 stop6h 08mAmerican Airlines
Deal found 3/27$302
This United Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/295:54 pmSTL - SFO
Nonstop4h 28mUnited Airlines
Tue 5/1311:02 amSFO - STL
Nonstop4h 07mUnited Airlines
Deal found 3/27$319
This Expedia deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/247:55 pmSTL - SFO
1 stop6h 14mMultiple Airlines
Tue 5/278:00 amSFO - STL
2 stops14h 04mMultiple Airlines
Deal found 3/27$331
This United Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/245:45 amSGF - SFO
1 stop6h 00mUnited Airlines
Thu 7/317:15 amSFO - SGF
1 stop9h 16mUnited Airlines
Deal found 3/27$335
This Alaska Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/247:00 amMCI - SFO
2 stops13h 26mAlaska Airlines
Tue 4/298:00 amSFO - MCI
1 stop13h 59mAlaska Airlines
Deal found 3/26$336
This Delta deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/111:32 pmSTL - SFO
1 stop7h 18mDelta
Tue 6/175:05 pmSFO - STL
1 stop5h 31mDelta
Deal found 3/27$339
This Southwest deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/72:20 pmSTL - SFO
2 stops10h 20mSouthwest
Wed 5/1412:45 pmSFO - STL
1 stop6h 50mSouthwest
Deal found 3/27$344
This Expedia deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/237:51 pmMCI - SFO
1 stop6h 18mMultiple Airlines
Tue 5/277:24 amSFO - MCI
2 stops14h 14mMultiple Airlines
Deal found 3/27$361

Cheapflights Fare Finder

Customize your flight search to find flights from Missouri to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
Use the filters below to find and compare flights from Missouri to San Francisco that are best for you.

Fly from

Missouri

Fly to

San Francisco

Route

Depart

Return

Price

Kansas CitySan Francisco

MCI - SFO

MCISFO

Kansas City

Wed 4/23

5:44 pm-11:59 pm

1 stop8h 15m

San Francisco

Fri 4/25

12:47 am-10:33 am

1 stop7h 46m

$237

St. LouisSan Francisco

STL - SFO

STLSFO

Lambert-St Louis

Tue 4/29

5:41 pm-1:19 pm

1 stop21h 38m

San Francisco

Mon 5/12

9:59 pm-12:06 am

1 stop24h 07m

$240

Kansas CitySan Francisco

MCI - SFO

MCISFO

Kansas City

Mon 5/5

8:51 pm-2:44 pm

1 stop19h 53m

San Francisco

Thu 5/8

4:17 pm-7:51 pm

1 stop25h 34m

$240

St. LouisSan Francisco

STL - SFO

STLSFO

Lambert-St Louis

Fri 5/23

5:00 pm-10:58 pm

1 stop7h 58m

San Francisco

Fri 5/30

11:59 pm-2:54 pm

1 stop12h 55m

$265

SpringfieldSan Francisco

SGF - SFO

SGFSFO

Springfield-Branson

Wed 5/7

11:33 am-7:41 pm

1 stop10h 08m

San Francisco

Sat 5/10

12:21 am-10:51 am

1 stop8h 30m

$289

St. LouisSan Francisco

STL - SFO

STLSFO

Lambert-St Louis

Wed 4/16

6:44 am-3:44 pm

2 stops11h 00m

San Francisco

Sat 4/19

10:59 pm-12:16 pm

1 stop11h 17m

$296

St. LouisSan Francisco

STL - SFO

STLSFO

Lambert-St Louis

Tue 4/29

5:45 am-2:55 pm

1 stop11h 10m

San Francisco

Wed 4/30

12:47 am-9:01 am

1 stop6h 14m

$300

St. LouisSan Francisco

STL - SFO

STLSFO

Lambert-St Louis

Tue 5/6

1:40 pm-4:00 pm

Nonstop4h 20m

San Francisco

Sun 5/11

6:10 am-11:55 am

Nonstop3h 45m

$315

St. LouisSan Francisco

STL - SFO

STLSFO

Lambert-St Louis

Tue 4/29

5:54 pm-8:22 pm

Nonstop4h 28m

San Francisco

Tue 5/13

11:02 am-5:09 pm

Nonstop4h 07m

$319

St. LouisSan Francisco

STL - SFO

STLSFO

Lambert-St Louis

Wed 4/23

6:30 am-1:32 pm

1 stop9h 02m

San Francisco

Wed 4/30

8:20 am-11:59 pm

2 stops13h 39m

$322

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/28

Showing 1-10 of 39 results
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Best time to book a flight from Missouri to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to San Francisco

What is the cheapest month to book a flight from Missouri to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Missouri to San Francisco (average of $276). Flying from Missouri to San Francisco in June is currently the most expensive (average of $398). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to SFO?

Find hourly flight availability from Missouri to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 28, 2025.

When flying from Missouri to San Francisco, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in San Francisco by month

Plan your trip to San Francisco by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in San Francisco ranges from 0.0 - 4.4 inches per month. January is typically the wettest month, when rainfall can reach 4.4 in. July is typically the driest time to visit San Francisco when rainfall is around 0.0 in.

Temperature in San Francisco by month

Plan your trip to San Francisco by taking into account the average temperature totals by month.

If weather is an important factor for your trip to San Francisco, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated March 28, 2025.
See what other customers who have flown with Southwest, Alaska Airlines and Delta from Missouri to San Francisco have to say. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,273 reviews

Overall

8.1

Boarding

8.2

Entertainment

7.6

Comfort

8.1

Crew

8.6

Food

7.1

Reviews

1 / 20
10.0
Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.
Southwest
8.1
Very good
4,273 reviews
Southwest
8.1
Very good
4,273 reviews

Overall

8.1

Boarding

8.2

Entertainment

7.6

Comfort

8.1

Crew

8.6

Food

7.1

Reviews

1 / 20
10.0
Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.
Alaska Airlines
8.0
Very good
9,798 reviews
Southwest
8.1
Very good
4,273 reviews

Overall

8.1

Boarding

8.2

Entertainment

7.6

Comfort

8.1

Crew

8.6

Food

7.1

Reviews

1 / 20
10.0
Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.
Delta
8.0
Very good
7,896 reviews
Southwest
8.1
Very good
4,273 reviews

Overall

8.1

Boarding

8.2

Entertainment

7.6

Comfort

8.1

Crew

8.6

Food

7.1

Reviews

1 / 20
10.0
Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.
Hawaiian Airlines
7.9
Good
2,335 reviews
Southwest
8.1
Very good
4,273 reviews

Overall

8.1

Boarding

8.2

Entertainment

7.6

Comfort

8.1

Crew

8.6

Food

7.1

Reviews

1 / 20
10.0
Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.
United Airlines
7.4
Good
8,603 reviews
Southwest
8.1
Very good
4,273 reviews

Overall

8.1

Boarding

8.2

Entertainment

7.6

Comfort

8.1

Crew

8.6

Food

7.1

Reviews

1 / 20
10.0
Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.

Related info for your journey

Find useful and relevant information for your journey from Missouri to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Francisco from Missouri?

    San Francisco (SFO) is the airport you will fly into if you book a flight from Missouri to San Francisco. It is only a 11.8 mi journey from San Francisco (SFO) to San Francisco’s city center.

  • How popular is this Missouri to San Francisco flight route?

    Flights from Missouri to San Francisco have been viewed 9 times in the past calendar month.

  • What are the cheapest airlines to fly from Missouri to San Francisco one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $115. However, be on the lookout for offers from Hawaiian Airlines and Delta, as they are both options that can get you from Missouri to San Francisco for a low price.

  • What are the most popular routes from Missouri to San Francisco?

    The most popular flight routes from Missouri to San Francisco are Kansas City - San Francisco, Lambert-St Louis - San Francisco and Springfield-Branson - San Francisco.

  • What are the most reliable airlines from Missouri to San Francisco?

    Before booking your flight to San Francisco from Missouri, check out the most reliable airlines to get you to your destination on time: Asiana Airlines (87%), Air New Zealand (87%), United Airlines( 83%).

  • What are the cheapest flights from Missouri to San Francisco?

    On average you can expect to pay $2,359 for a flight from Missouri to San Francisco. The cheapest flight overall is $134 while the most popular route, (Kansas City - San Francisco) is currently priced at $231.

  • Can I find deals for flights from Missouri to San Francisco that include hotel bookings?

    Yes. In addition to deals on Missouri to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to San Francisco.

  • Can I find deals for business class flights from Missouri to San Francisco?

    Yes. Cheapflights offers flight deals from Missouri to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to San Francisco?

    Currently, January is the cheapest month in which you can book a flight from Missouri to San Francisco (average of $276). Flying from Missouri to San Francisco in June is currently the most expensive (average of $398). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Missouri?

Book flights to Missouri if you plan to visit one of these locations
Roseville
Mountain View
Santa Cruz
Turlock
Fairfield
South San Francisco
Manteca
Sausalito
Richmond
Watsonville
Hollister
Milpitas
Antioch
Hayward
Vallejo
Newark
Alameda
Campbell
Daly City
Pacific Grove

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Missouri to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from Missouri to San Francisco

Discover the top 6 airlines that operate flights from Missouri to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$99Average$197FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$194Average$424FlexibilityNo cancel feeOn-time71%
DeltaCheapest$216Average$330FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$236Average$432FlexibilityNo cancel feeOn-time69%
Alaska AirlinesCheapest$267Average$417FlexibilityNo cancel feeOn-time75%
SouthwestCheapest$299Average$426FlexibilityNo cancel feeOn-time63%
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