What are the cheapest airlines flying from Key West to San Francisco round-trip?

American Airlines, at $228, was found to be the cheapest airline from Key West to San Francisco.Alternate airlines to your destination round-trip include Delta and United Airlines.

What are the cheapest airlines to fly from Key West to San Francisco one-way?

For one-way options, check prices for Delta. According to our data, you can fly for as low as $129. Users have also found prices from $152 and $238 on American Airlines and United Airlines, respectively.

What is the cheapest month to book a flight from Key West to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Key West to San Francisco (average of $276). Flying from Key West to San Francisco in June is currently the most expensive (average of $393). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest day to fly from Key West to San Francisco?

Travelers seeking maximum savings on their Key West to San Francisco flight should consider departing on Friday evenings when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

What is the cheapest day to fly round-trip from Key West to San Francisco?

Friday is generally a great day to depart. Flying on this day could help you save up to 56%.

Most accurate provider : When it comes to deals on Key West-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Key West-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Key West-San Francisco flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Key West-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Key West-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Key West to San Francisco that include hotel bookings?

Yes. In addition to deals on Key West to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Key West to San Francisco?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key West to San Francisco.

Can I find deals for business class flights from Key West to San Francisco?

Yes. Cheapflights offers flight deals from Key West to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$129+ Flights from Key West to San Francisco

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1. Tell us where you want to go

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2. Select your favorite providers

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Cheap flight deals from Key West to San Francisco

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars
Round-trip from	$228 (American Airlines)
One-way from	$129 (Delta)

Provider with most accurate pricing for Key West-San Francisco flight deals.

Search Deals

Provider most trusted by Cheapflights users for Key West-San Francisco flights.

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From Key West to San Francisco

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One-way flight from Key West to San Francisco

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Find flight deals from Key West to San Francisco

Cheapest flights from Key West to San Francisco
Explore the most affordable flight options available from Key West to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 11, 2025.

Thu 5/155:24 pmEYW - SFO

1 stop8h 37mAmerican Airlines

Sat 5/2411:53 pmSFO - EYW

1 stop9h 58mAmerican Airlines

Deal found 4/10

$228

Thu 5/86:25 pmEYW - SFO

1 stop8h 07mDelta

Sun 5/1111:59 pmSFO - EYW

1 stop7h 52mDelta

Deal found 4/10

$257

Wed 5/72:18 pmEYW - SFO

1 stop12h 38mUnited Airlines

Fri 5/912:43 amSFO - EYW

2 stops14h 22mUnited Airlines

Deal found 4/10

$472

Best flights from Key West to San Francisco
Discover carefully curated flight deals from Key West to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 11, 2025.

Thu 5/155:24 pmEYW - SFO

1 stop8h 37mAmerican Airlines

Sat 5/2411:53 pmSFO - EYW

1 stop9h 58mAmerican Airlines

Deal found 4/10

$228

Thu 5/86:25 pmEYW - SFO

1 stop8h 07mDelta

Sun 5/1111:59 pmSFO - EYW

1 stop7h 52mDelta

Deal found 4/10

$257

Wed 5/72:18 pmEYW - SFO

1 stop12h 38mUnited Airlines

Fri 5/912:43 amSFO - EYW

2 stops14h 22mUnited Airlines

Deal found 4/10

$472

Last-minute flights from Key West to San Francisco
Discover last-minute flight deals from Key West to San Francisco. Data last updated April 11, 2025 and is based on user searches.

Wed 5/72:18 pmEYW - SFO

1 stop12h 38mUnited Airlines

Fri 5/912:43 amSFO - EYW

2 stops14h 22mUnited Airlines

Deal found 4/10

$472

Thu 5/86:25 pmEYW - SFO

1 stop8h 07mDelta

Sun 5/1111:59 pmSFO - EYW

1 stop7h 52mDelta

Deal found 4/10

$257

Thu 5/155:24 pmEYW - SFO

1 stop8h 37mAmerican Airlines

Sat 5/2411:53 pmSFO - EYW

1 stop9h 58mAmerican Airlines

Deal found 4/10

$228

One-way flights from Key West to San Francisco
Search for one-way flight options from Key West to San Francisco. Find affordable one-way fares based on user searches. Data last updated April 11, 2025.

Thu 7/32:05 pmEYW - SFO

1 stop7h 42mDelta

Deal found 4/10

$129

Tue 7/111:20 amEYW - SFO

1 stop10h 40mAmerican Airlines

Deal found 4/10

$152

Mon 6/308:45 amEYW - SFO

1 stop28h 00mUnited Airlines

Deal found 4/10

$238

Cheapflights Fare Finder

Use the filters below to find and compare flights from Key West to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Key WestSan Francisco

EYW - SFO

EYWSFO

Key West

Thu 5/15

5:24 pm-11:01 pm

1 stop8h 37m

San Francisco

Sat 5/24

11:53 pm-12:51 pm

1 stop9h 58m

$228

Key WestSan Francisco

EYW - SFO

EYWSFO

Key West

Thu 5/8

6:25 pm-11:32 pm

1 stop8h 07m

San Francisco

Sun 5/11

11:59 pm-10:51 am

1 stop7h 52m

$257

Key WestSan Francisco

EYW - SFO

EYWSFO

Key West

Wed 5/7

2:18 pm-11:56 pm

1 stop12h 38m

San Francisco

Fri 5/9

12:43 am-6:05 pm

2 stops14h 22m

$472

Key WestSan Francisco

EYW - SFO

EYWSFO

Key West

Thu 7/3

2:05 pm-6:47 pm

1 stop7h 42m

$129

Key WestSan Francisco

EYW - SFO

EYWSFO

Key West

Tue 7/1

11:20 am-7:00 pm

1 stop10h 40m

$152

Key WestSan Francisco

EYW - SFO

EYWSFO

Key West

Mon 6/30

8:45 am-9:45 am

1 stop28h 00m

$238

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/10

Compare providers for flights from Key West to San Francisco

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Key West to San Francisco in April.

Provider	Price Accuracy	Trust Score*
FlightHub	Price Accuracy3 stars	Trust Score*3 stars
eDreams	Price Accuracy3 stars	Trust Score*3 stars
Expedia	Price Accuracy1 star	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Key West-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Key West-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Key West-San Francisco flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Key West-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Key West-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Key West to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Key West with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Key West to San Francisco

What is the cheapest time of day to fly from EYW to SFO?

When flying from Key West to San Francisco, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 20% versus a flight at noon.

Rainfall in San Francisco by month

In terms of precipitation, rainfall in San Francisco ranges from 0.0 - 4.4 inches per month. January is typically the wettest month, when rainfall can reach 4.4 in. July is typically the driest time to visit San Francisco when rainfall is around 0.0 in.

Temperature in San Francisco by month

If weather is an important factor for your trip to San Francisco, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

Reviews of airlines servicing San Francisco

Delta

8.0

Very good

7,911 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta

8.0

Very good

7,911 reviews

Delta

8.0

Very good

7,911 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

United Airlines

7.4

Good

8,636 reviews

Delta

8.0

Very good

7,911 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,911 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

What are the cheapest airlines flying from Key West to San Francisco round-trip?
American Airlines, at $228, was found to be the cheapest airline from Key West to San Francisco.Alternate airlines to your destination round-trip include Delta and United Airlines.
What are the cheapest airlines to fly from Key West to San Francisco one-way?
For one-way options, check prices for Delta. According to our data, you can fly for as low as $129. Users have also found prices from $152 and $238 on American Airlines and United Airlines, respectively.
Can I find deals for flights from Key West to San Francisco that include hotel bookings?
Yes. In addition to deals on Key West to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Key West to San Francisco?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key West to San Francisco.
Can I find deals for business class flights from Key West to San Francisco?
Yes. Cheapflights offers flight deals from Key West to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Key West to San Francisco?
Currently, January is the cheapest month in which you can book a flight from Key West to San Francisco (average of $276). Flying from Key West to San Francisco in June is currently the most expensive (average of $393). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Roseville

Mountain View

Santa Cruz

Turlock

South San Francisco

Fairfield

Manteca

Sausalito

Richmond

Watsonville

Hollister

Milpitas

Antioch

Hayward

Vallejo

Newark

Alameda

Sunnyvale

Campbell

Daly City

Browse thousands of different options on Cheapflights for your next trip

Top airline flying from Key West to San Francisco

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$355	Average$608	FlexibilityNo cancel fee	On-time71%

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$129+ Cheap flights from Key West to San Francisco (EYW - SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/3. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Key West to San Francisco with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Key West to San Francisco

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Find flight deals from Key West to San Francisco

Cheapest flights from Key West to San FranciscoExplore the most affordable flight options available from Key West to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 11, 2025.

Explore the most affordable flight options available from Key West to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 11, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Key West to San Francisco that are best for you.

Compare providers for flights from Key West to San Francisco

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Key West to San Francisco in April.

Best time to book a flight from Key West to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Key West with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Key West to San Francisco

What is the cheapest time of day to fly from EYW to SFO?

Find hourly flight availability from Key West to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 11, 2025.

Rainfall in San Francisco by month

Plan your trip to San Francisco by taking into account the average rainfall totals by month.

Temperature in San Francisco by month

Plan your trip to San Francisco by taking into account the average temperature totals by month.

Reviews of airlines servicing San Francisco

Related info for your journey

Find useful and relevant information for your journey from Key West to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Key West to San Francisco round-trip?

What are the cheapest airlines to fly from Key West to San Francisco one-way?

Can I find deals for flights from Key West to San Francisco that include hotel bookings?

How can I find direct flights from Key West to San Francisco?

Can I find deals for business class flights from Key West to San Francisco?

What is the cheapest month to book a flight from Key West to San Francisco?

Traveling to a place near Key West?

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Alternative routes for Key West to San Francisco

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Top airline flying from Key West to San Francisco

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Travel Smart

Cheapest flights from Key West to San Francisco
Explore the most affordable flight options available from Key West to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 11, 2025.