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$153+ Cheap flights from Key West to San Francisco (EYW - SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/31. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — SFO
2月 26 — 3月 51
水 2/26
水 3/5
1 adult, Economy
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1. Tell us where you want to go
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Cheap flight deals from Key West to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Key West (EYW) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 2月 21, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$257
(Delta)

One-way from

$153
(Trip.com)
Provider with most accurate pricing for Key West-San Francisco flight deals.
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Provider most trusted by Cheapflights users for Key West-San Francisco flights.
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From Key West to San Francisco
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One-way flight from Key West to San Francisco
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Find flight deals from Key West to San Francisco

Cheapest flights from Key West to San Francisco
Explore the most affordable flight options available from Key West to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 2月 21, 2025.

This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
木 4/106:10 pmEYW - SFO
1 stop9h 09mDelta
火 4/226:00 amSFO - EYW
1 stop8h 17mDelta
Deal found 2/19$257
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
木 4/105:20 pmEYW - SFO
1 stop8h 31mAmerican Airlines
火 4/226:00 amSFO - EYW
2 stops9h 45mAmerican Airlines
Deal found 2/19$262
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
木 4/104:04 pmEYW - SFO
3 stops21h 51mUnited Airlines
火 4/2211:59 pmSFO - EYW
2 stops15h 56mUnited Airlines
Deal found 2/19$525

Find flights from Key West to San Francisco within your budget

Customize your flight search to find flights from Key West to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated 2月 21, 2025.

Fly from

Key West

Fly to

San Francisco

Route

Depart

Return

Price

Key WestSan Francisco

EYW - SFO

EYWSFO

Key West

木 4/10

6:10 pm-12:19 am

1 stop9h 09m

San Francisco

火 4/22

6:00 am-5:17 pm

1 stop8h 17m

$257

Key WestSan Francisco

EYW - SFO

EYWSFO

Key West

木 4/10

5:20 pm-10:51 pm

1 stop8h 31m

San Francisco

火 4/22

6:00 am-6:45 pm

2 stops9h 45m

$262

Key WestSan Francisco

EYW - SFO

EYWSFO

Key West

木 4/10

4:04 pm-10:55 am

3 stops21h 51m

San Francisco

火 4/22

11:59 pm-6:55 pm

2 stops15h 56m

$525

Key WestSan Francisco

EYW - SFO

EYWSFO

Key West

月 3/31

7:40 pm-9:30 pm

1 stop28h 50m

$153

Key WestSan Francisco

EYW - SFO

EYWSFO

Key West

金 7/18

3:09 pm-10:37 pm

1 stop10h 28m

$220

Key WestSan Francisco

EYW - SFO

EYWSFO

Key West

金 7/18

10:55 am-11:59 pm

2 stops16h 04m

$249

Key WestSan Francisco

EYW - SFO

EYWSFO

Key West

木 3/27

6:15 pm-12:22 am

1 stop9h 07m

$359

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/20

Compare providers for flights from Key West to San Francisco

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Key West to San Francisco in February.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
ExpediaPrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Key West-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Key West-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Key West-San Francisco flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Key West-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Key West-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Key West to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Key West with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Key West to San Francisco

Get recent, data-driven insights about flights from Key West to San Francisco including ideal travel times, pricing trends, and more.

What is the cheapest time of day to fly from EYW to SFO?

Find hourly flight availability from Key West to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 2月 21, 2025.

When flying from Key West to San Francisco, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 20% versus a flight at noon.

Rainfall in San Francisco by month

Plan your trip to San Francisco by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in San Francisco ranges from 0.0 - 4.4 inches per month. January is typically the wettest month, when rainfall can reach 4.4 in. July is typically the driest time to visit San Francisco when rainfall is around 0.0 in.

Temperature in San Francisco by month

Plan your trip to San Francisco by taking into account the average temperature totals by month.

If weather is an important factor for your trip to San Francisco, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated 2月 21, 2025.
Delta
8.0
Very good
8,219 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Comfort

8.0

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta
8.0
Very good
8,219 reviews
Delta
8.0
Very good
8,219 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Comfort

8.0

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

United Airlines
7.4
Good
8,765 reviews
Delta
8.0
Very good
8,219 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Comfort

8.0

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,219 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Comfort

8.0

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Key West to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Key West to San Francisco round-trip?

    Delta, at $257, was found to be the cheapest airline from Key West to San Francisco.Alternate airlines to your destination round-trip include American Airlines and United Airlines.

  • What are the cheapest airlines to fly from Key West to San Francisco one-way?

    For one-way options, check prices for American Airlines. According to our data, you can fly for as low as $220. Users have also found prices from $249 and $359 on United Airlines and Delta, respectively.

  • Can I find deals for flights from Key West to San Francisco that include hotel bookings?

    Yes. In addition to deals on Key West to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Key West to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key West to San Francisco.

  • Can I find deals for business class flights from Key West to San Francisco?

    Yes. Cheapflights offers flight deals from Key West to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Key West to San Francisco?

    Currently, January is the cheapest month in which you can book a flight from Key West to San Francisco (average of $276). Flying from Key West to San Francisco in June is currently the most expensive (average of $403). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Roseville
Mountain View
Turlock
Santa Cruz
Fairfield
Manteca
Sausalito
Watsonville
Hayward
Richmond
Hollister
South San Francisco
Antioch
Milpitas
Vallejo
Newark
Alameda
Campbell
Pacific Grove
Sunnyvale

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Key West to San Francisco

Discover the top airline that operate flights from Key West to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated 2月 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$317Average$608FlexibilityNo cancel feeOn-time71%
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