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$118+ Cheap flights from Key Largo, FL to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/1. Fares are subject to change and may not be available on all flights or dates of travel.
MIA — SFO
Apr 2 — Apr 91
Wed 4/2
Wed 4/9
1 adult, Economy
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Cheapflights Tip: The best prices from Key Largo to San Francisco are usually found in January or October, booked 70 days in advance, depart on a Thursday or Friday and return on a Monday

Cheap flight deals from Key Largo to San Francisco

Keep the following information in mind while searching for Key Largo to San Francisco flight deals. Data was last updated March 28, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$218
(United Airlines)

One-way from

$118
(Cheapflightsfares)

Popular in

June

Cheapest in

January

Average price

$350
Provider with most accurate pricing for Miami-San Francisco flight deals.
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Provider most trusted by Cheapflights users for Miami-San Francisco flights.
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From Key Largo to San Francisco
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One-way flight from Key Largo to San Francisco
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Highest demand for flights based on searches. 16% potential increase in price ($67 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Find flight deals from Key Largo to San Francisco

Cheapest flights from Key Largo to San Francisco
Explore the most affordable flight options available from Key Largo to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 28, 2025.

This United Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/39:30 amMIA - SFO
1 stop11h 12mUnited Airlines
Wed 5/710:47 pmSFO - MIA
Nonstop5h 42mUnited Airlines
Deal found 3/27$218
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/227:30 pmMIA - SFO
Nonstop6h 24mAmerican Airlines
Thu 5/81:20 pmSFO - MIA
Nonstop5h 31mAmerican Airlines
Deal found 3/27$228
This Frontier deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/13:55 pmMIA - SFO
1 stop9h 27mFrontier
Sun 5/412:11 amSFO - MIA
1 stop13h 11mFrontier
Deal found 3/27$238
This Southwest deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/195:05 amMIA - SFO
1 stop10h 20mSouthwest
Sat 4/261:15 pmSFO - MIA
1 stop7h 35mSouthwest
Deal found 3/27$249
This Alaska Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/136:20 pmMIA - SFO
1 stop17h 56mAlaska Airlines
Tue 8/198:49 pmSFO - MIA
1 stop17h 17mAlaska Airlines
Deal found 3/27$256
This Delta deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/167:00 amMIA - SFO
1 stop10h 21mDelta
Sat 8/236:00 amSFO - MIA
1 stop8h 39mDelta
Deal found 3/27$257
This JetBlue Airways deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/317:00 amMIA - SFO
1 stop10h 31mJetBlue
Sun 6/16:00 amSFO - MIA
1 stop14h 13mJetBlue
Deal found 3/27$292
This Trip.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/106:25 amMIA - SFO
1 stop21h 19mMultiple Airlines
Mon 4/2112:43 amSFO - MIA
1 stop7h 41mMultiple Airlines
Deal found 3/27$336

Cheapflights Fare Finder

Customize your flight search to find flights from Key Largo to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
Use the filters below to find and compare flights from Key Largo to San Francisco that are best for you.

Fly from

Key Largo

Fly to

San Francisco

Route

Depart

Return

Price

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Sat 5/3

9:30 am-5:42 pm

1 stop11h 12m

San Francisco

Wed 5/7

10:47 pm-7:29 am

Nonstop5h 42m

$218

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Tue 4/22

7:30 pm-10:54 pm

Nonstop6h 24m

San Francisco

Thu 5/8

1:20 pm-9:51 pm

Nonstop5h 31m

$228

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Thu 5/1

3:55 pm-10:22 pm

1 stop9h 27m

San Francisco

Sun 5/4

12:11 am-4:22 pm

1 stop13h 11m

$238

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Sat 4/19

5:05 am-12:25 pm

1 stop10h 20m

San Francisco

Sat 4/26

1:15 pm-11:50 pm

1 stop7h 35m

$249

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Wed 8/13

6:20 pm-9:16 am

1 stop17h 56m

San Francisco

Tue 8/19

8:49 pm-5:06 pm

1 stop17h 17m

$256

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Sat 8/16

7:00 am-2:21 pm

1 stop10h 21m

San Francisco

Sat 8/23

6:00 am-5:39 pm

1 stop8h 39m

$257

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Sat 5/31

7:00 am-2:31 pm

1 stop10h 31m

San Francisco

Sun 6/1

6:00 am-11:13 pm

1 stop14h 13m

$292

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Thu 4/10

6:25 am-12:44 am

1 stop21h 19m

San Francisco

Mon 4/21

12:43 am-11:24 am

1 stop7h 41m

$336

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Thu 5/1

3:55 pm-10:22 pm

1 stop9h 27m

$118

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Thu 4/17

4:48 pm-8:15 pm

Nonstop6h 27m

$119

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/27

Showing 1-10 of 15 results
1
2

Best time to book a flight from Key Largo to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Key Largo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Key Largo to San Francisco

How far ahead should I book a flight from Key Largo to San Francisco?

Use this chart to determine the optimal time to book a round-trip flight from Key Largo to San Francisco. Price data was last updated on March 21, 2025.

The price you pay for your flight from Key Largo to San Francisco may vary depending on when you book. For the best chance of a lower fare, look to book 70 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Key Largo to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Key Largo to San Francisco (average of $276). Flying from Key Largo to San Francisco in June is currently the most expensive (average of $398). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from KE9 to SFO?

Find hourly flight availability from Key Largo to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 28, 2025.

When flying from Key Largo to San Francisco, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What is the cheapest day to fly from Key Largo to San Francisco?

Use this chart to determine the cheapest time to fly round-trip from Key Largo to San Francisco. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Key Largo to San Francisco flight should consider departing on Thursday at noon when fares are most often at their lowest. Saturday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Key Largo to San Francisco

Explore weekly flight availability from Key Largo to San Francisco. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated March 28, 2025.

The most flights from KE9 to SFO are scheduled on a Thursday (29 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (11 on average).

Rainfall in San Francisco by month

Plan your trip to San Francisco by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in San Francisco ranges from 0.0 - 4.4 inches per month. January is typically the wettest month, when rainfall can reach 4.4 in. July is typically the driest time to visit San Francisco when rainfall is around 0.0 in.

Temperature in San Francisco by month

Plan your trip to San Francisco by taking into account the average temperature totals by month.

If weather is an important factor for your trip to San Francisco, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated March 28, 2025.
To help decide which airline to fly from Key Largo to San Francisco, see what other customers have to say about Southwest, Alaska Airlines and Delta. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,273 reviews

Entertainment

7.6

Comfort

8.1

Boarding

8.2

Food

7.1

Overall

8.1

Crew

8.6

Reviews

1 / 20
10.0
Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.
Southwest
8.1
Very good
4,273 reviews
Southwest
8.1
Very good
4,273 reviews

Entertainment

7.6

Comfort

8.1

Boarding

8.2

Food

7.1

Overall

8.1

Crew

8.6

Reviews

1 / 20
10.0
Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.
Alaska Airlines
8.0
Very good
9,798 reviews
Southwest
8.1
Very good
4,273 reviews

Entertainment

7.6

Comfort

8.1

Boarding

8.2

Food

7.1

Overall

8.1

Crew

8.6

Reviews

1 / 20
10.0
Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.
Delta
8.0
Very good
7,896 reviews
Southwest
8.1
Very good
4,273 reviews

Entertainment

7.6

Comfort

8.1

Boarding

8.2

Food

7.1

Overall

8.1

Crew

8.6

Reviews

1 / 20
10.0
Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.
United Airlines
7.4
Good
8,603 reviews
Southwest
8.1
Very good
4,273 reviews

Entertainment

7.6

Comfort

8.1

Boarding

8.2

Food

7.1

Overall

8.1

Crew

8.6

Reviews

1 / 20
10.0
Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.
JetBlue
7.3
Good
2,923 reviews
Southwest
8.1
Very good
4,273 reviews

Entertainment

7.6

Comfort

8.1

Boarding

8.2

Food

7.1

Overall

8.1

Crew

8.6

Reviews

1 / 20
10.0
Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.

Related info for your journey

Find useful and relevant information for your journey from Key Largo to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Francisco from Key Largo?

    San Francisco (SFO), located 11.8 mi from the city center, is the airport you fly into when you book flights from Key Largo to San Francisco. 6 airlines have flights to San Francisco from Key Largo on a regular basis. Booking flights from Key Largo to San Francisco should not be difficult; the airport handles an average of 17 inbound flights from Key Largo per day.

  • How popular is this Key Largo to San Francisco flight route?

    The Key Largo to San Francisco flight path was viewed by 59 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines to fly from Key Largo to San Francisco one-way?

    The cheapest airlines for a one-way flight from Key Largo to San Francisco are Frontier ($118), United Airlines ($119), and American Airlines ($120).

  • What are the most reliable airlines from Key Largo to San Francisco?

    No one likes to see their flight delayed. When booking a flight from Key Largo to San Francisco consider choosing Royal Air Maroc (90%), Japan Airlines (89%) or Cathay Pacific (86%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Key Largo to San Francisco?

    Looking for the cheapest flight from Key Largo to San Francisco? While on average our users pay $1,763, our data indicates the cheapest price to be $108. The most popular route (Miami - San Francisco), is priced around $179.

  • Can I find deals for flights from Key Largo to San Francisco that include hotel bookings?

    Yes. In addition to deals on Key Largo to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Key Largo to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key Largo to San Francisco.

  • Can I find deals for business class flights from Key Largo to San Francisco?

    Yes. Cheapflights offers flight deals from Key Largo to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Key Largo to San Francisco?

    Currently, January is the cheapest month in which you can book a flight from Key Largo to San Francisco (average of $276). Flying from Key Largo to San Francisco in June is currently the most expensive (average of $398). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Key Largo?

Book flights to Key Largo if you plan to visit one of these locations
Roseville
Mountain View
Santa Cruz
Turlock
Fairfield
South San Francisco
Manteca
Sausalito
Richmond
Watsonville
Hollister
Milpitas
Antioch
Hayward
Vallejo
Newark
Alameda
Campbell
Daly City
Pacific Grove

Browse thousands of different options on Cheapflights for your next trip

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Top 6 airlines flying from Key Largo to San Francisco

Discover the top 6 airlines that operate flights from Key Largo to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$81Average$190FlexibilityNo cancel feeOn-time62%
JetBlueCheapest$89Average$298FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$105Average$412FlexibilityNo cancel feeOn-time71%
DeltaCheapest$128Average$290FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$178Average$347FlexibilityNo cancel feeOn-time69%
Alaska AirlinesCheapest$188Average$332FlexibilityNo cancel feeOn-time75%
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