What are the cheapest airlines to fly from Italy to San Francisco one-way?

One-way options have recently been found by users for as low as $321 on TAP AIR PORTUGAL. Other airlines that offer cheap prices include Aer Lingus from $476 and Iberia from $490 one-way.

What are the most popular routes from Italy to San Francisco?

The most popular route from Italy to San Francisco is Rome Fiumicino - San Francisco. You may also consider Milan Malpensa - San Francisco or Milan Linate - San Francisco.

How far in advance should I book a flight from Italy to San Francisco?

To save on the cost of your flight from Italy to San Francisco, book at least 61 days before your planned departure. Booking around this time can save you about 45% on the cost of this flight compared to booking a flight leaving this week. We have found prices from $648 if you need a flight within two weeks. For flights within the next 72 hours, you can find tickets from as low as $648.

What is the cheapest month to fly from Italy to San Francisco?

The best pricing can be found in the month of March. Prices to San Francisco from Italy average $685. You can even find prices in March for less than $685, as users have found deals to San Francisco from as low as $440. The month of July appears to be one of the more expensive times to travel to San Francisco from Italy. Flying in the targeted month can save you up to 25%.

What airport do you fly into for flights to San Francisco from Italy?

Located just 11.8 mi from the city center, San Francisco (SFO) is the airport most travelers will use when flying to San Francisco from Italy.

Can I find deals for flights from Italy to San Francisco that include hotel bookings?

Yes. In addition to deals on Italy to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Italy to San Francisco?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Italy to San Francisco.

Can I find deals for business class flights from Italy to San Francisco?

Yes. Cheapflights offers flight deals from Italy to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$526+ Flights from Italy to San Francisco

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1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

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Cheap flight deals from Italy to San Francisco

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars
Round-trip from	$497 (Flysmarter)
One-way from	$279 (Mytrip)
Popular in	July
Cheapest in	March
Average price	$566
Good round-trip deal	$685 or less
Good one-way deal	$673 or less

Provider with most accurate pricing for Rome (ROM)-San Francisco flight deals.

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Provider most trusted by Cheapflights users for Rome (ROM)-San Francisco flights.

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From Italy to San Francisco

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One-way flight from Italy to San Francisco

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Highest demand for flights based on searches. 13% potential increase in price ($110 potential increase over avg. RT price).

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Cheapest flight prices on average. 2% potential price decrease ($16 potential savings vs. average RT price).

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Average for round-trip flights in March 2025

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Price to beat on a round-trip flight from Italy to San Francisco.

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Price to beat on a one-way flight from Italy to San Francisco.

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Find flight deals from Italy to San Francisco

Cheapest flights from Italy to San Francisco
Explore the most affordable flight options available from Italy to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 28, 2025.

Fri 5/211:25 amFLR - SFO

1 stop34h 50mITA Airways

Thu 5/83:15 pmSFO - FLR

1 stop18h 00mITA Airways

Deal found 3/26

$450

Sun 5/113:00 pmNAP - SFO

1 stop17h 49mBritish Airways

Sun 5/185:49 pmSFO - NAP

2 stops19h 11mBritish Airways

Deal found 3/26

$497

Thu 8/218:05 pmBLQ - SFO

1 stop29h 25mScandinavian Airlines

Sat 9/67:40 pmSFO - BLQ

1 stop14h 45mScandinavian Airlines

Deal found 3/27

$504

Tue 8/269:40 amBLQ - SFO

2 stops21h 39mMultiple Airlines

Thu 9/411:59 pmSFO - BLQ

2 stops33h 31mMultiple Airlines

Deal found 3/27

$507

Thu 9/117:50 amBLQ - SFO

1 stop15h 00mAmerican Airlines

Mon 10/204:35 pmSFO - BLQ

1 stop22h 10mAmerican Airlines

Deal found 3/27

$513

Thu 5/17:00 pmVRN - SFO

2 stops33h 04mFinnair

Wed 5/712:57 pmSFO - VRN

2 stops20h 18mFinnair

Deal found 3/27

$515

Tue 8/267:50 amBLQ - SFO

1 stop15h 00mBritish Airways

Thu 9/44:35 pmSFO - BLQ

1 stop22h 20mBritish Airways

Deal found 3/27

$515

Thu 4/37:05 amFLR - SFO

1 stop15h 45mBritish Airways

Mon 4/74:20 pmSFO - FLR

1 stop21h 00mBritish Airways

Deal found 3/27

$519

Thu 8/283:00 pmNAP - SFO

1 stop16h 55mAmerican Airlines

Mon 9/87:20 pmSFO - NAP

1 stop17h 40mAmerican Airlines

Deal found 3/27

$523

Mon 9/157:10 pmBLQ - SFO

1 stop27h 05mITA Airways

Tue 10/2110:45 pmSFO - BLQ

2 stops34h 40mITA Airways

Deal found 3/27

$527

Mon 8/2510:25 amMXP - SFO

2 stops21h 30mMultiple Airlines

Sun 9/74:35 pmSFO - MXP

1 stop16h 55mMultiple Airlines

Deal found 3/27

$532

Thu 5/87:50 amLIN - SFO

2 stops20h 47mMultiple Airlines

Thu 5/154:20 pmSFO - LIN

1 stop15h 55mMultiple Airlines

Deal found 3/27

$533

Best flights from Italy to San Francisco
Discover carefully curated flight deals from Italy to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 28, 2025.

Sun 5/113:00 pmNAP - SFO

1 stop17h 49mBritish Airways

Sun 5/185:49 pmSFO - NAP

2 stops19h 11mBritish Airways

Deal found 3/26

$497

Thu 8/218:05 pmBLQ - SFO

1 stop29h 25mScandinavian Airlines

Sat 9/67:40 pmSFO - BLQ

1 stop14h 45mScandinavian Airlines

Deal found 3/27

$504

Tue 8/269:40 amBLQ - SFO

2 stops21h 39mMultiple Airlines

Thu 9/411:59 pmSFO - BLQ

2 stops33h 31mMultiple Airlines

Deal found 3/27

$507

Thu 9/117:50 amBLQ - SFO

1 stop15h 00mAmerican Airlines

Mon 10/204:35 pmSFO - BLQ

1 stop22h 10mAmerican Airlines

Deal found 3/27

$513

Thu 5/17:00 pmVRN - SFO

2 stops33h 04mFinnair

Wed 5/712:57 pmSFO - VRN

2 stops20h 18mFinnair

Deal found 3/27

$515

Mon 9/157:10 pmBLQ - SFO

1 stop27h 05mITA Airways

Tue 10/2110:45 pmSFO - BLQ

2 stops34h 40mITA Airways

Deal found 3/27

$527

Mon 9/15:55 amFCO - SFO

1 stop17h 35mTAP AIR PORTUGAL

Sat 9/67:20 pmSFO - FCO

1 stop30h 00mTAP AIR PORTUGAL

Deal found 3/27

$542

Wed 4/1610:00 amFCO - SFO

1 stop21h 36mIberia

Wed 4/238:05 amSFO - FCO

1 stop15h 00mIberia

Deal found 3/27

$553

Sun 5/119:20 pmVRN - SFO

1 stop23h 25mKLM

Sun 5/183:05 pmSFO - VRN

1 stop13h 25mKLM

Deal found 3/27

$592

Thu 4/176:00 amVCE - SFO

1 stop14h 45mDelta

Tue 4/223:05 pmSFO - VCE

1 stop17h 40mDelta

Deal found 3/27

$592

Sun 5/46:05 amBLQ - SFO

2 stops40h 07mUnited Airlines

Sat 5/171:05 pmSFO - BLQ

2 stops18h 35mUnited Airlines

Deal found 3/27

$613

Tue 4/228:45 pmLIN - SFO

1 stop25h 05mAir France

Tue 4/293:05 pmSFO - LIN

1 stop13h 50mAir France

Deal found 3/27

$614

Last-minute flights from Italy to San Francisco
Discover last-minute flight deals from Italy to San Francisco. Data last updated March 28, 2025 and is based on user searches.

Wed 4/211:20 amNAP - SFO

2 stops32h 15mITA Airways

Tue 4/83:15 pmSFO - NAP

1 stop18h 35mITA Airways

Deal found 3/27

$579

Thu 4/37:05 amFLR - SFO

1 stop15h 45mBritish Airways

Mon 4/74:20 pmSFO - FLR

1 stop21h 00mBritish Airways

Deal found 3/27

$519

Thu 4/311:10 amNAP - SFO

2 stops21h 09mBritish Airways

Thu 4/104:20 pmSFO - NAP

1 stop20h 40mBritish Airways

Deal found 3/27

$533

Thu 4/31:35 pmFCO - SFO

1 stop19h 45mAmerican Airlines

Wed 4/1612:47 amSFO - FCO

1 stop22h 18mAmerican Airlines

Deal found 3/27

$543

Thu 4/310:00 amFCO - SFO

1 stop18h 00mBritish Airways

Thu 4/1710:48 pmSFO - FCO

2 stops29h 22mBritish Airways

Deal found 3/27

$548

Thu 4/312:40 pmVCE - SFO

2 stops20h 48mBritish Airways

Wed 4/162:45 pmSFO - VCE

2 stops18h 15mBritish Airways

Deal found 3/27

$561

Thu 4/37:40 pmFCO - SFO

1 stop25h 05mKLM

Thu 4/179:39 amSFO - FCO

1 stop15h 26mKLM

Deal found 3/27

$566

Thu 4/39:05 amNAP - SFO

1 stop35h 40mKLM

Tue 4/83:05 pmSFO - NAP

1 stop18h 10mKLM

Deal found 3/27

$589

Thu 4/36:30 amFLR - SFO

2 stops21h 37mDelta

Mon 4/77:10 amSFO - FLR

2 stops16h 55mDelta

Deal found 3/27

$597

Thu 4/37:05 amFLR - SFO

1 stop15h 45mMultiple Airlines

Mon 4/77:30 pmSFO - FLR

1 stop17h 50mMultiple Airlines

Deal found 3/26

$535

Fri 4/46:50 amNAP - SFO

2 stops35h 44mAmerican Airlines

Sun 4/62:27 pmSFO - NAP

2 stops23h 08mAmerican Airlines

Deal found 3/28

$550

Sun 4/61:35 pmFCO - SFO

1 stop19h 35mIberia

Fri 4/182:45 pmSFO - FCO

1 stop33h 25mIberia

Deal found 3/27

$551

One-way flights from Italy to San Francisco
Search for one-way flight options from Italy to San Francisco. Find affordable one-way fares based on user searches. Data last updated March 28, 2025.

Tue 5/63:20 pmTSF - SFO

3 stops39h 05mMultiple Airlines

Deal found 3/27

$279

Wed 5/149:45 pmNAP - SFO

2 stops52h 05mMultiple Airlines

Deal found 3/28

$283

Tue 5/69:00 pmVCE - SFO

2 stops33h 25mMultiple Airlines

Deal found 3/27

$319

Thu 5/87:15 pmFLR - SFO

1 stop30h 35mTAP AIR PORTUGAL

Deal found 3/27

$321

Sat 5/311:35 pmBGY - SFO

3 stops42h 55mMultiple Airlines

Deal found 3/26

$321

Thu 5/87:30 pmFLR - SFO

2 stops30h 20mMultiple Airlines

Deal found 3/27

$342

Wed 5/1412:30 pmNAP - SFO

1 stop35h 00mTAP AIR PORTUGAL

Deal found 3/28

$363

Tue 8/266:15 amVRN - SFO

3 stops44h 00mMultiple Airlines

Deal found 3/27

$370

Sat 5/312:00 pmMXP - SFO

2 stops57h 05mMultiple Airlines

Deal found 3/26

$397

Thu 5/14:00 pmLIN - SFO

2 stops30h 34mMultiple Airlines

Deal found 3/27

$431

Sun 5/187:00 amFCO - SFO

2 stops33h 31mMultiple Airlines

Deal found 3/28

$444

Mon 5/55:25 pmMXP - SFO

1 stop30h 10mTAP AIR PORTUGAL

Deal found 3/26

$446

Cheapflights Fare Finder

Use the filters below to find and compare flights from Italy to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

NaplesSan Francisco

NAP - SFO

NAPSFO

Naples

Sun 5/11

3:00 pm-11:49 pm

1 stop17h 49m

San Francisco

Sun 5/18

5:49 pm-10:00 pm

2 stops19h 11m

$497

BolognaSan Francisco

BLQ - SFO

BLQSFO

Bologna Guglielmo Marconi

Thu 8/21

8:05 pm-4:30 pm

1 stop29h 25m

San Francisco

Sat 9/6

7:40 pm-7:25 pm

1 stop14h 45m

$504

BolognaSan Francisco

BLQ - SFO

BLQSFO

Bologna Guglielmo Marconi

Tue 8/26

9:40 am-10:19 pm

2 stops21h 39m

San Francisco

Thu 9/4

11:59 pm-6:30 pm

2 stops33h 31m

$507

BolognaSan Francisco

BLQ - SFO

BLQSFO

Bologna Guglielmo Marconi

Thu 9/11

7:50 am-1:50 pm

1 stop15h 00m

San Francisco

Mon 10/20

4:35 pm-11:45 pm

1 stop22h 10m

$513

VeronaSan Francisco

VRN - SFO

VRNSFO

Verona

Thu 5/1

7:00 pm-7:04 pm

2 stops33h 04m

San Francisco

Wed 5/7

12:57 pm-6:15 pm

2 stops20h 18m

$515

BolognaSan Francisco

BLQ - SFO

BLQSFO

Bologna Guglielmo Marconi

Tue 8/26

7:50 am-1:50 pm

1 stop15h 00m

San Francisco

Thu 9/4

4:35 pm-11:55 pm

1 stop22h 20m

$515

FlorenceSan Francisco

FLR - SFO

FLRSFO

Florence Peretola

Thu 4/24

7:05 am-5:15 pm

1 stop19h 10m

San Francisco

Mon 4/28

7:30 pm-10:20 pm

1 stop17h 50m

$520

NaplesSan Francisco

NAP - SFO

NAPSFO

Naples

Thu 8/28

3:00 pm-10:55 pm

1 stop16h 55m

San Francisco

Mon 9/8

7:20 pm-10:00 pm

1 stop17h 40m

$523

BolognaSan Francisco

BLQ - SFO

BLQSFO

Bologna Guglielmo Marconi

Mon 9/15

7:10 pm-1:15 pm

1 stop27h 05m

San Francisco

Tue 10/21

10:45 pm-6:25 pm

2 stops34h 40m

$527

MilanSan Francisco

MXP - SFO

MXPSFO

Milan Malpensa

Mon 8/25

10:25 am-10:55 pm

2 stops21h 30m

San Francisco

Sun 9/7

4:35 pm-6:30 pm

1 stop16h 55m

$532

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/27

Showing 1-10 of 60 results

...

Best time to book a flight from Italy to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Italy with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Italy to San Francisco

What is the cheapest month to book a flight from Italy to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Italy to San Francisco (average of $276). Flying from Italy to San Francisco in June is currently the most expensive (average of $398). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IT to SFO?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Italy to San Francisco as you normally would.

Rainfall in San Francisco by month

In terms of precipitation, rainfall in San Francisco ranges from 0.0 - 4.4 inches per month. January is typically the wettest month, when rainfall can reach 4.4 in. July is typically the driest time to visit San Francisco when rainfall is around 0.0 in.

Temperature in San Francisco by month

If weather is an important factor for your trip to San Francisco, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

Reviews of airlines servicing San Francisco

Get a feel of what it's like to fly with Delta, Emirates and KLM from Italy to San Francisco by reading reviews from past customers. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,896 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta

8.0

Very good

7,896 reviews

Delta

8.0

Very good

7,896 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Emirates

8.0

Very good

3,190 reviews

Delta

8.0

Very good

7,896 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

KLM

7.8

Good

1,321 reviews

Delta

8.0

Very good

7,896 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Finnair

7.6

Good

1,267 reviews

Delta

8.0

Very good

7,896 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

SWISS

7.5

Good

1,570 reviews

Delta

8.0

Very good

7,896 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

What airport do you fly into for flights to San Francisco from Italy?
Located just 11.8 mi from the city center, San Francisco (SFO) is the airport most travelers will use when flying to San Francisco from Italy.
What are the cheapest airlines to fly from Italy to San Francisco one-way?
One-way options have recently been found by users for as low as $321 on TAP AIR PORTUGAL. Other airlines that offer cheap prices include Aer Lingus from $476 and Iberia from $490 one-way.
What are the most popular routes from Italy to San Francisco?
The most popular route from Italy to San Francisco is Rome Fiumicino - San Francisco. You may also consider Milan Malpensa - San Francisco or Milan Linate - San Francisco.
Can I find deals for flights from Italy to San Francisco that include hotel bookings?
Yes. In addition to deals on Italy to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Italy to San Francisco?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Italy to San Francisco.
Can I find deals for business class flights from Italy to San Francisco?
Yes. Cheapflights offers flight deals from Italy to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Italy to San Francisco?
Currently, January is the cheapest month in which you can book a flight from Italy to San Francisco (average of $276). Flying from Italy to San Francisco in June is currently the most expensive (average of $398). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Roseville

Mountain View

Santa Cruz

Turlock

Fairfield

South San Francisco

Manteca

Sausalito

Richmond

Watsonville

Hollister

Milpitas

Antioch

Hayward

Vallejo

Newark

Alameda

Campbell

Daly City

Pacific Grove

Browse thousands of different options on Cheapflights for your next trip

Top 8 airlines flying from Italy to San Francisco

Airline	Cheapest	Average	Flexibility	On-time
TAP AIR PORTUGAL	Cheapest$426	Average$573	FlexibilityNo cancel fee	On-timeN/A
ITA Airways	Cheapest$484	Average$787	FlexibilityNo cancel fee	On-time81%
United Airlines	Cheapest$517	Average$702	FlexibilityNo cancel fee	On-time69%
Iberia	Cheapest$542	Average$561	FlexibilityNo cancel fee	On-time77%
British Airways	Cheapest$552	Average$803	FlexibilityNo cancel fee	On-time70%
American Airlines	Cheapest$555	Average$720	FlexibilityNo cancel fee	On-time71%
Lufthansa	Cheapest$570	Average$727	FlexibilityNo cancel fee	On-time76%
SWISS	Cheapest$597	Average$928	FlexibilityNo cancel fee	On-time79%

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$279+ Cheap flights from Italy to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/6. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Italy to San Francisco with Cheapflights

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3. Compare prices and book

Cheap flight deals from Italy to San Francisco

Keep the following information in mind while searching for Italy to San Francisco flight deals. Data was last updated March 28, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Find flight deals from Italy to San Francisco

Cheapest flights from Italy to San FranciscoExplore the most affordable flight options available from Italy to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 28, 2025.

Explore the most affordable flight options available from Italy to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 28, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Italy to San Francisco that are best for you.

Best time to book a flight from Italy to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Italy with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Italy to San Francisco

What is the cheapest month to book a flight from Italy to San Francisco?

What is the cheapest time of day to fly from IT to SFO?

Find hourly flight availability from Italy to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 28, 2025.

Rainfall in San Francisco by month

Plan your trip to San Francisco by taking into account the average rainfall totals by month.

Temperature in San Francisco by month

Plan your trip to San Francisco by taking into account the average temperature totals by month.

Reviews of airlines servicing San Francisco

Get a feel of what it's like to fly with Delta, Emirates and KLM from Italy to San Francisco by reading reviews from past customers. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Italy to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to San Francisco from Italy?

What are the cheapest airlines to fly from Italy to San Francisco one-way?

What are the most popular routes from Italy to San Francisco?

Can I find deals for flights from Italy to San Francisco that include hotel bookings?

How can I find direct flights from Italy to San Francisco?

Can I find deals for business class flights from Italy to San Francisco?

What is the cheapest month to book a flight from Italy to San Francisco?

Traveling to a place near Italy?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Italy to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.

Top 8 airlines flying from Italy to San Francisco

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Cheapest flights from Italy to San Francisco
Explore the most affordable flight options available from Italy to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 28, 2025.