What are the cheapest airlines to fly from Italy to San Francisco one-way?

One-way options have recently been found by users for as low as $331 on TAP AIR PORTUGAL. Other airlines that offer cheap prices include Vueling from $396 and Iberia from $416 one-way.

What are the most popular routes from Italy to San Francisco?

The most popular route from Italy to San Francisco is Rome Fiumicino - San Francisco. You may also consider Milan Malpensa - San Francisco or Milan Linate - San Francisco.

How far in advance should I book a flight from Italy to San Francisco?

To save on the cost of your flight from Italy to San Francisco, book at least 61 days before your planned departure. Booking around this time can save you about 45% on the cost of this flight compared to booking a flight leaving this week. We have found prices from $648 if you need a flight within two weeks. For flights within the next 72 hours, you can find tickets from as low as $648.

What is the cheapest month to fly from Italy to San Francisco?

The best pricing can be found in the month of March. Prices to San Francisco from Italy average $688. You can even find prices in March for less than $688, as users have found deals to San Francisco from as low as $440. The month of July appears to be one of the more expensive times to travel to San Francisco from Italy. Flying in the targeted month can save you up to 26%.

What airport do you fly into for flights to San Francisco from Italy?

Located just 11.8 mi from the city center, San Francisco (SFO) is the airport most travelers will use when flying to San Francisco from Italy.

Can I find deals for flights from Italy to San Francisco that include hotel bookings?

Yes. In addition to deals on Italy to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Italy to San Francisco?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Italy to San Francisco.

Can I find deals for business class flights from Italy to San Francisco?

Yes. Cheapflights offers flight deals from Italy to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$548+ Flights from Italy to San Francisco

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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

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Cheap flight deals from Italy to San Francisco

Most accurate provider	AranGrant 3 stars
Most trusted provider	AranGrant 3 stars
Round-trip from	$525 (lol.travel)
One-way from	$307 (Kiwi.com)
Popular in	July
Cheapest in	March
Average price	$673
Good round-trip deal	$744 or less
Good one-way deal	$685 or less

Provider with most accurate pricing for Rome (ROM)-San Francisco flight deals.

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Provider most trusted by Cheapflights users for Rome (ROM)-San Francisco flights.

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From Italy to San Francisco

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One-way flight from Italy to San Francisco

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Highest demand for flights based on searches. 13% potential increase in price ($110 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($17 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in April 2025

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Price to beat on a round-trip flight from Italy to San Francisco.

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Price to beat on a one-way flight from Italy to San Francisco.

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Find flight deals from Italy to San Francisco

Cheapest flights from Italy to San Francisco
Explore the most affordable flight options available from Italy to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.

Mon 5/128:20 amFCO - SFO

1 stop15h 10mCondor

Mon 5/194:30 pmSFO - FCO

1 stop15h 25mCondor

Deal found 4/16

$453

Sat 5/1012:00 pmNAP - SFO

1 stop19h 05mBritish Airways

Sun 5/2512:57 pmSFO - NAP

2 stops21h 28mBritish Airways

Deal found 4/16

$525

Wed 5/1412:15 pmVCE - SFO

1 stop18h 50mBritish Airways

Thu 5/227:30 pmSFO - VCE

1 stop19h 20mBritish Airways

Deal found 4/15

$527

Fri 5/27:25 amLIN - SFO

1 stop18h 50mBritish Airways

Mon 5/127:30 pmSFO - LIN

1 stop14h 25mBritish Airways

Deal found 4/17

$531

Sat 5/39:00 amMXP - SFO

2 stops23h 34mMultiple Airlines

Wed 5/74:30 pmSFO - MXP

1 stop14h 45mMultiple Airlines

Deal found 4/17

$535

Sat 5/179:05 pmBLQ - SFO

1 stop25h 45mBritish Airways

Sat 5/247:30 pmSFO - BLQ

1 stop19h 20mBritish Airways

Deal found 4/17

$536

Wed 4/3011:10 amMXP - SFO

1 stop22h 00mBritish Airways

Wed 5/77:21 amSFO - MXP

1 stop16h 49mBritish Airways

Deal found 4/17

$536

Sat 5/1012:00 pmNAP - SFO

1 stop19h 05mAmerican Airlines

Sun 5/257:30 pmSFO - NAP

1 stop14h 55mAmerican Airlines

Deal found 4/17

$542

Tue 8/269:40 amBLQ - SFO

2 stops21h 39mMultiple Airlines

Thu 9/411:59 pmSFO - BLQ

2 stops33h 31mMultiple Airlines

Deal found 4/17

$542

Mon 5/127:05 amFLR - SFO

1 stop19h 10mBritish Airways

Tue 5/274:20 pmSFO - FLR

1 stop21h 00mBritish Airways

Deal found 4/16

$543

Tue 9/21:20 pmMXP - SFO

1 stop17h 24mAmerican Airlines

Thu 9/184:35 pmSFO - MXP

1 stop22h 05mAmerican Airlines

Deal found 4/17

$543

Sat 5/177:50 amBLQ - SFO

2 stops22h 10mAmerican Airlines

Sat 5/244:20 pmSFO - BLQ

1 stop17h 55mAmerican Airlines

Deal found 4/17

$544

Best flights from Italy to San Francisco
Discover carefully curated flight deals from Italy to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 17, 2025.

Sat 5/1012:00 pmNAP - SFO

1 stop19h 05mBritish Airways

Sun 5/2512:57 pmSFO - NAP

2 stops21h 28mBritish Airways

Deal found 4/16

$525

Sat 5/39:00 amMXP - SFO

2 stops23h 34mMultiple Airlines

Wed 5/74:30 pmSFO - MXP

1 stop14h 45mMultiple Airlines

Deal found 4/17

$535

Sat 5/1012:00 pmNAP - SFO

1 stop19h 05mAmerican Airlines

Sun 5/257:30 pmSFO - NAP

1 stop14h 55mAmerican Airlines

Deal found 4/17

$542

Sat 5/178:00 amFCO - SFO

1 stop15h 30mCondor

Sat 5/244:30 pmSFO - FCO

1 stop15h 25mCondor

Deal found 4/17

$563

Tue 9/212:00 pmVCE - SFO

2 stops21h 10mIberia

Tue 9/92:28 pmSFO - VCE

2 stops19h 32mIberia

Deal found 4/17

$579

Wed 5/2111:20 amVCE - SFO

1 stop34h 55mITA Airways

Wed 6/43:15 pmSFO - VCE

1 stop14h 15mITA Airways

Deal found 4/17

$592

Wed 5/216:00 amVCE - SFO

1 stop14h 45mDelta

Wed 6/41:45 pmSFO - VCE

2 stops19h 00mDelta

Deal found 4/16

$618

Mon 9/18:05 pmMXP - SFO

1 stop29h 25mScandinavian Airlines

Fri 9/197:40 pmSFO - MXP

1 stop13h 45mScandinavian Airlines

Deal found 4/17

$622

Wed 8/205:45 pmFCO - SFO

1 stop29h 45mTAP AIR PORTUGAL

Tue 9/166:45 pmSFO - FCO

2 stops33h 00mTAP AIR PORTUGAL

Deal found 4/17

$631

Wed 8/207:40 pmFLR - SFO

1 stop25h 05mKLM

Mon 9/158:25 pmSFO - FLR

1 stop17h 20mKLM

Deal found 4/16

$664

Tue 5/67:55 pmVCE - SFO

1 stop23h 40mTurkish Airlines

Sat 5/106:45 pmSFO - VCE

1 stop39h 10mTurkish Airlines

Deal found 4/17

$677

Tue 8/2610:40 amFCO - SFO

2 stops20h 39mFinnair

Sat 9/133:00 pmSFO - FCO

2 stops33h 45mFinnair

Deal found 4/17

$691

Last-minute flights from Italy to San Francisco
Discover last-minute flight deals from Italy to San Francisco. Data last updated April 17, 2025 and is based on user searches.

Wed 4/236:55 pmMXP - SFO

1 stop27h 55mBritish Airways

Wed 4/304:20 pmSFO - MXP

1 stop22h 20mBritish Airways

Deal found 4/16

$549

Wed 4/236:55 amFCO - SFO

1 stop15h 55mBritish Airways

Wed 4/307:30 pmSFO - FCO

1 stop18h 35mBritish Airways

Deal found 4/16

$562

Thu 4/2412:15 pmVCE - SFO

1 stop19h 21mBritish Airways

Wed 4/304:20 pmSFO - VCE

1 stop17h 40mBritish Airways

Deal found 4/16

$538

Thu 4/248:20 amFCO - SFO

2 stops20h 53mMultiple Airlines

Thu 5/84:30 pmSFO - FCO

1 stop15h 25mMultiple Airlines

Deal found 4/17

$563

Thu 4/247:50 amBLQ - SFO

2 stops22h 24mBritish Airways

Wed 5/78:00 amSFO - BLQ

2 stops25h 35mBritish Airways

Deal found 4/17

$578

Thu 4/247:25 amLIN - SFO

1 stop18h 50mBritish Airways

Mon 5/54:20 pmSFO - LIN

1 stop15h 55mBritish Airways

Deal found 4/17

$583

Thu 4/2412:15 pmVCE - SFO

1 stop19h 21mAmerican Airlines

Wed 5/72:50 pmSFO - VCE

2 stops18h 10mAmerican Airlines

Deal found 4/16

$594

Thu 4/246:20 amMXP - SFO

2 stops24h 19mMultiple Airlines

Sun 5/44:30 pmSFO - MXP

1 stop14h 45mMultiple Airlines

Deal found 4/17

$603

Thu 4/2412:10 pmFCO - SFO

1 stop17h 55mAmerican Airlines

Thu 5/87:30 pmSFO - FCO

1 stop19h 25mAmerican Airlines

Deal found 4/16

$611

Thu 4/249:10 amFCO - SFO

Nonstop13h 05mITA Airways

Thu 5/83:15 pmSFO - FCO

Nonstop12h 00mITA Airways

Deal found 4/16

$627

Fri 4/2511:40 amMXP - SFO

1 stop20h 52mDelta

Sat 5/107:00 amSFO - MXP

2 stops19h 00mDelta

Deal found 4/17

$631

Sat 4/2611:10 amMXP - SFO

1 stop22h 00mAmerican Airlines

Mon 5/54:20 pmSFO - MXP

1 stop19h 25mAmerican Airlines

Deal found 4/17

$543

One-way flights from Italy to San Francisco
Search for one-way flight options from Italy to San Francisco. Find affordable one-way fares based on user searches. Data last updated April 17, 2025.

Wed 5/212:10 pmBGY - SFO

2 stops50h 21mMultiple Airlines

Deal found 4/17

$307

Tue 5/204:35 pmNAP - SFO

2 stops47h 56mMultiple Airlines

Deal found 4/16

$319

Thu 5/17:15 pmNAP - SFO

1 stop30h 35mTAP AIR PORTUGAL

Deal found 4/16

$331

Wed 5/2112:05 pmFLR - SFO

1 stop35h 25mTAP AIR PORTUGAL

Deal found 4/16

$341

Wed 5/216:25 amFLR - SFO

2 stops23h 02mMultiple Airlines

Deal found 4/16

$353

Tue 9/1610:05 amNAP - SFO

1 stop17h 05mVueling

Deal found 4/17

$396

Wed 5/218:40 amLIN - SFO

2 stops31h 51mMultiple Airlines

Deal found 4/17

$402

Wed 5/217:50 pmMXP - SFO

3 stops29h 15mMultiple Airlines

Deal found 4/17

$402

Sun 9/288:10 amMXP - SFO

1 stop19h 00mIberia

Deal found 4/17

$416

Tue 6/178:15 pmMXP - SFO

1 stop27h 20mTAP AIR PORTUGAL

Deal found 4/17

$431

Thu 7/38:00 amBLQ - SFO

3 stops36h 15mMultiple Airlines

Deal found 4/17

$432

Tue 5/69:15 amVCE - SFO

1 stop17h 45mIberia

Deal found 4/16

$438

Cheapflights Fare Finder

Use the filters below to find and compare flights from Italy to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

RomeSan Francisco

FCO - SFO

FCOSFO

Rome Fiumicino

Mon 5/12

8:20 am-2:30 pm

1 stop15h 10m

San Francisco

Mon 5/19

4:30 pm-4:55 pm

1 stop15h 25m

$453

NaplesSan Francisco

NAP - SFO

NAPSFO

Naples

Sat 5/10

12:00 pm-10:05 pm

1 stop19h 05m

San Francisco

Sun 5/25

12:57 pm-7:25 pm

2 stops21h 28m

$525

VeniceSan Francisco

VCE - SFO

VCESFO

Venice Marco Polo

Wed 5/14

12:15 pm-10:05 pm

1 stop18h 50m

San Francisco

Thu 5/22

7:30 pm-11:50 pm

1 stop19h 20m

$527

MilanSan Francisco

LIN - SFO

LINSFO

Milan Linate

Fri 5/2

7:25 am-5:15 pm

1 stop18h 50m

San Francisco

Mon 5/12

7:30 pm-6:55 pm

1 stop14h 25m

$531

MilanSan Francisco

MXP - SFO

MXPSFO

Milan Malpensa

Sat 5/3

9:00 am-11:34 pm

2 stops23h 34m

San Francisco

Wed 5/7

4:30 pm-4:15 pm

1 stop14h 45m

$535

BolognaSan Francisco

BLQ - SFO

BLQSFO

Bologna Guglielmo Marconi

Sat 5/17

9:05 pm-1:50 pm

1 stop25h 45m

San Francisco

Sat 5/24

7:30 pm-11:50 pm

1 stop19h 20m

$536

NaplesSan Francisco

NAP - SFO

NAPSFO

Naples

Sat 5/10

12:00 pm-10:05 pm

1 stop19h 05m

San Francisco

Sun 5/25

7:30 pm-7:25 pm

1 stop14h 55m

$542

BolognaSan Francisco

BLQ - SFO

BLQSFO

Bologna Guglielmo Marconi

Tue 8/26

9:40 am-10:19 pm

2 stops21h 39m

San Francisco

Thu 9/4

11:59 pm-6:30 pm

2 stops33h 31m

$542

MilanSan Francisco

MXP - SFO

MXPSFO

Milan Malpensa

Tue 9/2

1:20 pm-9:44 pm

1 stop17h 24m

San Francisco

Tue 9/16

4:35 pm-11:45 pm

1 stop22h 10m

$543

BolognaSan Francisco

BLQ - SFO

BLQSFO

Bologna Guglielmo Marconi

Sat 5/17

7:50 am-9:00 pm

2 stops22h 10m

San Francisco

Sat 5/24

4:20 pm-7:15 pm

1 stop17h 55m

$544

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/17

Showing 1-10 of 60 results

...

Best time to book a flight from Italy to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Italy with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Italy to San Francisco

What is the cheapest month to book a flight from Italy to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Italy to San Francisco (average of $276). Flying from Italy to San Francisco in June is currently the most expensive (average of $393). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IT to SFO?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Italy to San Francisco as you normally would.

Rainfall in San Francisco by month

In terms of precipitation, rainfall in San Francisco ranges from 0.0 - 4.4 inches per month. January is typically the wettest month, when rainfall can reach 4.4 in. July is typically the driest time to visit San Francisco when rainfall is around 0.0 in.

Temperature in San Francisco by month

If weather is an important factor for your trip to San Francisco, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

Reviews of airlines servicing San Francisco

Get a feel of what it's like to fly with Delta, Emirates and KLM from Italy to San Francisco by reading reviews from past customers. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,916 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta

8.0

Very good

7,916 reviews

Delta

8.0

Very good

7,916 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Emirates

8.0

Very good

3,200 reviews

Delta

8.0

Very good

7,916 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

KLM

7.8

Good

1,327 reviews

Delta

8.0

Very good

7,916 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Finnair

7.6

Good

1,269 reviews

Delta

8.0

Very good

7,916 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

SWISS

7.5

Good

1,580 reviews

Delta

8.0

Very good

7,916 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

What airport do you fly into for flights to San Francisco from Italy?
Located just 11.8 mi from the city center, San Francisco (SFO) is the airport most travelers will use when flying to San Francisco from Italy.
What are the cheapest airlines to fly from Italy to San Francisco one-way?
One-way options have recently been found by users for as low as $331 on TAP AIR PORTUGAL. Other airlines that offer cheap prices include Vueling from $396 and Iberia from $416 one-way.
What are the most popular routes from Italy to San Francisco?
The most popular route from Italy to San Francisco is Rome Fiumicino - San Francisco. You may also consider Milan Malpensa - San Francisco or Milan Linate - San Francisco.
Can I find deals for flights from Italy to San Francisco that include hotel bookings?
Yes. In addition to deals on Italy to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Italy to San Francisco?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Italy to San Francisco.
Can I find deals for business class flights from Italy to San Francisco?
Yes. Cheapflights offers flight deals from Italy to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Italy to San Francisco?
Currently, January is the cheapest month in which you can book a flight from Italy to San Francisco (average of $276). Flying from Italy to San Francisco in June is currently the most expensive (average of $393). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Roseville

Mountain View

Santa Cruz

Turlock

South San Francisco

Fairfield

Manteca

Sausalito

Richmond

Watsonville

Hollister

Milpitas

Antioch

Vallejo

Newark

Hayward

Alameda

Sunnyvale

Livermore

Campbell

Browse thousands of different options on Cheapflights for your next trip

Top 8 airlines flying from Italy to San Francisco

Airline	Cheapest	Average	Flexibility	On-time
TAP AIR PORTUGAL	Cheapest$426	Average$573	FlexibilityNo cancel fee	On-timeN/A
ITA Airways	Cheapest$484	Average$846	FlexibilityNo cancel fee	On-time81%
United Airlines	Cheapest$517	Average$716	FlexibilityNo cancel fee	On-time69%
Iberia	Cheapest$542	Average$561	FlexibilityNo cancel fee	On-time77%
British Airways	Cheapest$552	Average$778	FlexibilityNo cancel fee	On-time70%
American Airlines	Cheapest$555	Average$720	FlexibilityNo cancel fee	On-time71%
Lufthansa	Cheapest$570	Average$728	FlexibilityNo cancel fee	On-time76%
SWISS	Cheapest$606	Average$943	FlexibilityNo cancel fee	On-time79%

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$307+ Cheap flights from Italy to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/21. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Italy to San Francisco with Cheapflights

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Cheap flight deals from Italy to San Francisco

Keep the following information in mind while searching for Italy to San Francisco flight deals. Data was last updated April 17, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Find flight deals from Italy to San Francisco

Cheapest flights from Italy to San FranciscoExplore the most affordable flight options available from Italy to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.

Explore the most affordable flight options available from Italy to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Italy to San Francisco that are best for you.

Best time to book a flight from Italy to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Italy with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Italy to San Francisco

What is the cheapest month to book a flight from Italy to San Francisco?

What is the cheapest time of day to fly from IT to SFO?

Find hourly flight availability from Italy to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 17, 2025.

Rainfall in San Francisco by month

Plan your trip to San Francisco by taking into account the average rainfall totals by month.

Temperature in San Francisco by month

Plan your trip to San Francisco by taking into account the average temperature totals by month.

Reviews of airlines servicing San Francisco

Get a feel of what it's like to fly with Delta, Emirates and KLM from Italy to San Francisco by reading reviews from past customers. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Italy to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to San Francisco from Italy?

What are the cheapest airlines to fly from Italy to San Francisco one-way?

What are the most popular routes from Italy to San Francisco?

Can I find deals for flights from Italy to San Francisco that include hotel bookings?

How can I find direct flights from Italy to San Francisco?

Can I find deals for business class flights from Italy to San Francisco?

What is the cheapest month to book a flight from Italy to San Francisco?

Traveling to a place near Italy?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Italy to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.

Top 8 airlines flying from Italy to San Francisco

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Cheapest flights from Italy to San Francisco
Explore the most affordable flight options available from Italy to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.