What are the cheapest airlines flying from Harrisburg to San Francisco round-trip?

Cheapflights users have booked flights from Harrisburg to San Francisco round-trip from $309. Other airlines that can offer you cheap pricing are Delta, from $314, and Frontier, from $370. You may be able to fly from Harrisburg to San Francisco for 32% less than the average price by searching for these airlines.

What are the cheapest airlines to fly from Harrisburg to San Francisco one-way?

To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $106. American Airlines flights start at $195 while deals on Delta start at $200 one-way.

What is the cheapest day to fly from Harrisburg to San Francisco?

Travelers seeking maximum savings on their Harrisburg to San Francisco flight should consider departing on Wednesday at noon when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

What are the most popular airlines that fly from Harrisburg to San Francisco?

Before booking your flight from Harrisburg to San Francisco check out the most popular airlines for this route: American Airlines, Delta or United Airlines.

What is the cheapest day to fly round-trip from Harrisburg to San Francisco?

Saturday flights are generally found to be more expensive for flights from Harrisburg to San Francisco. This shouldn’t discourage you from searching, as you can still find great deals by being flexible with your options. Use our search form to find deals on tickets to San Francisco.

How far in advance should I book a flight from Harrisburg to San Francisco?

To save on the cost of your flight from Harrisburg to San Francisco, book at least 23 days before your planned departure. Booking around this time can save you about 35% on the cost of this flight compared to booking a flight leaving this week. We have found prices from $350 if you need a flight within two weeks. For flights within the next 72 hours, you can find tickets from as low as $350.

What is the cheapest month to fly from Harrisburg to San Francisco?

The best pricing can be found in the month of September. Prices to San Francisco from Harrisburg average $458. You can even find prices in September for less than $458, as users have found deals to San Francisco from as low as $258. The month of June appears to be one of the more expensive times to travel to San Francisco from Harrisburg. Flying in the targeted month can save you up to 47%.

Most accurate provider : When it comes to deals on Harrisburg-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Harrisburg-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Harrisburg-San Francisco flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Harrisburg-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Harrisburg-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Harrisburg to San Francisco that include hotel bookings?

Yes. In addition to deals on Harrisburg to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Harrisburg to San Francisco?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to San Francisco.

Can I find deals for business class flights from Harrisburg to San Francisco?

Yes. Cheapflights offers flight deals from Harrisburg to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$106+ Flights from Harrisburg to San Francisco

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1. Tell us where you want to go

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2. Select your favorite providers

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3. Compare prices and book

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Cheapflights Tip: The best prices from Harrisburg to San Francisco are usually found in September or April, booked 22 days in advance, depart on a Saturday or Tuesday and return on a Wednesday

Cheap flight deals from Harrisburg to San Francisco

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars
Round-trip from	$309 (United Airlines)
One-way from	$106 (Mytrip)
Popular in	June
Cheapest in	September
Average price	$355

Provider with most accurate pricing for Harrisburg-San Francisco flight deals.

Search Deals

Provider most trusted by Cheapflights users for Harrisburg-San Francisco flights.

Search Deals

From Harrisburg to San Francisco

Search Deals

One-way flight from Harrisburg to San Francisco

Search Deals

Highest demand for flights based on searches. 19% potential increase in price ($108 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 4% potential price decrease ($20 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in April 2025

Search Deals

Find flight deals from Harrisburg to San Francisco

Cheapest flights from Harrisburg to San Francisco
Explore the most affordable flight options available from Harrisburg to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 11, 2025.

Thu 5/83:20 pmMDT - SFO

1 stop9h 45mAmerican Airlines

Mon 8/1811:19 pmSFO - MDT

1 stop7h 41mAmerican Airlines

Deal found 4/9

$309

Thu 5/85:58 pmMDT - SFO

1 stop8h 34mDelta

Fri 8/226:00 amSFO - MDT

2 stops14h 42mDelta

Deal found 4/9

$314

Thu 4/105:40 pmMDT - SFO

1 stop30h 07mFrontier

Sat 4/1910:30 pmSFO - MDT

1 stop15h 20mFrontier

Deal found 4/9

$320

Thu 5/18:10 amMDT - SFO

1 stop8h 28mUnited Airlines

Sun 5/49:10 pmSFO - MDT

2 stops9h 29mUnited Airlines

Deal found 4/10

$328

Sun 5/256:59 pmMDT - SFO

3 stops30h 59mMultiple Airlines

Sun 6/16:09 pmSFO - MDT

2 stops19h 30mMultiple Airlines

Deal found 4/10

$559

Best flights from Harrisburg to San Francisco
Discover carefully curated flight deals from Harrisburg to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 11, 2025.

Thu 5/18:10 amMDT - SFO

1 stop10h 36mUnited Airlines

Sun 5/411:20 pmSFO - MDT

1 stop7h 57mUnited Airlines

Deal found 4/10

$309

Thu 5/85:58 pmMDT - SFO

1 stop8h 34mDelta

Tue 8/198:59 pmSFO - MDT

2 stops11h 53mDelta

Deal found 4/10

$314

Sat 5/318:12 pmMDT - SFO

1 stop17h 11mFrontier

Fri 6/68:48 pmSFO - MDT

1 stop14h 34mFrontier

Deal found 4/10

$370

Fri 5/95:00 amMDT - SFO

1 stop10h 34mAmerican Airlines

Mon 8/185:53 amSFO - MDT

1 stop10h 38mAmerican Airlines

Deal found 4/10

$374

Sat 5/179:15 amMDT - SFO

2 stops31h 48mMultiple Airlines

Sat 5/246:09 pmSFO - MDT

3 stops21h 00mMultiple Airlines

Deal found 4/10

$558

Last-minute flights from Harrisburg to San Francisco
Discover last-minute flight deals from Harrisburg to San Francisco. Data last updated April 11, 2025 and is based on user searches.

Thu 4/105:40 pmMDT - SFO

1 stop30h 07mFrontier

Sat 4/1910:30 pmSFO - MDT

1 stop15h 20mFrontier

Deal found 4/9

$320

Fri 4/1810:15 amMDT - SFO

1 stop8h 26mUnited Airlines

Sat 4/1912:08 amSFO - MDT

1 stop7h 09mUnited Airlines

Deal found 4/9

$599

Thu 5/18:10 amMDT - SFO

1 stop8h 28mUnited Airlines

Sun 5/49:10 pmSFO - MDT

2 stops9h 29mUnited Airlines

Deal found 4/10

$328

Thu 5/83:20 pmMDT - SFO

1 stop9h 45mAmerican Airlines

Mon 8/1811:19 pmSFO - MDT

1 stop7h 41mAmerican Airlines

Deal found 4/9

$309

Thu 5/85:58 pmMDT - SFO

1 stop8h 34mDelta

Fri 8/226:00 amSFO - MDT

2 stops14h 42mDelta

Deal found 4/9

$314

Sun 5/256:59 pmMDT - SFO

3 stops30h 59mMultiple Airlines

Sun 6/16:09 pmSFO - MDT

2 stops19h 30mMultiple Airlines

Deal found 4/10

$559

One-way flights from Harrisburg to San Francisco
Search for one-way flight options from Harrisburg to San Francisco. Find affordable one-way fares based on user searches. Data last updated April 11, 2025.

Sun 5/116:27 pmMDT - SFO

1 stop21h 48mFrontier

Deal found 4/8

$106

Fri 5/95:37 amMDT - SFO

1 stop8h 46mAmerican Airlines

Deal found 4/9

$195

Fri 5/96:00 amMDT - SFO

2 stops12h 15mDelta

Deal found 4/9

$200

Sun 5/116:15 amMDT - SFO

2 stops13h 34mUnited Airlines

Deal found 4/8

$250

Sun 5/117:12 pmMDT - SFO

3 stops25h 01mMultiple Airlines

Deal found 4/8

$525

Cheapflights Fare Finder

Use the filters below to find and compare flights from Harrisburg to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Thu 5/1

8:10 am-3:46 pm

1 stop10h 36m

San Francisco

Sun 5/4

11:20 pm-10:17 am

1 stop7h 57m

$309

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Thu 5/8

5:58 pm-11:32 pm

1 stop8h 34m

San Francisco

Mon 8/18

8:55 am-11:42 pm

2 stops11h 47m

$314

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Sat 5/31

8:12 pm-10:23 am

1 stop17h 11m

San Francisco

Fri 6/6

8:48 pm-2:22 pm

1 stop14h 34m

$370

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Fri 5/9

5:00 am-12:34 pm

1 stop10h 34m

San Francisco

Mon 8/18

5:53 am-7:31 pm

1 stop10h 38m

$374

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Sat 5/17

9:15 am-2:03 pm

2 stops31h 48m

San Francisco

Sat 5/24

6:09 pm-6:09 pm

3 stops21h 00m

$558

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Fri 5/9

3:20 pm-10:05 pm

1 stop9h 45m

$195

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Fri 5/9

6:00 am-3:15 pm

2 stops12h 15m

$200

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Fri 5/9

5:38 pm-9:36 am

3 stops18h 58m

$596

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/10

Compare providers for flights from Harrisburg to San Francisco

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Harrisburg to San Francisco in April.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy1 star	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*3 stars
eDreams	Price Accuracy3 stars	Trust Score*3 stars
Priceline	Price Accuracy1 star	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Harrisburg-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Harrisburg-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Harrisburg-San Francisco flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Harrisburg-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Harrisburg-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Harrisburg to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Harrisburg with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to San Francisco

How far ahead should I book a flight from Harrisburg to San Francisco?

The best time to book flights from Harrisburg to San Francisco is 22 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Harrisburg to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Harrisburg to San Francisco (average of $276). Flying from Harrisburg to San Francisco in June is currently the most expensive (average of $393). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MDT to SFO?

A simple way to save on the total cost of your ticket is to fly from Harrisburg to San Francisco at noon. If you’re flexible enough to do this you can expect to save up to 23% on your trip compared to booking a flight in the morning.

Rainfall in San Francisco by month

In terms of precipitation, rainfall in San Francisco ranges from 0.0 - 4.4 inches per month. January is typically the wettest month, when rainfall can reach 4.4 in. July is typically the driest time to visit San Francisco when rainfall is around 0.0 in.

Temperature in San Francisco by month

If weather is an important factor for your trip to San Francisco, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

Reviews of airlines servicing San Francisco

Delta

8.0

Very good

7,910 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta

8.0

Very good

7,910 reviews

Delta

8.0

Very good

7,910 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

United Airlines

7.4

Good

8,636 reviews

Delta

8.0

Very good

7,910 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,910 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Frontier

6.0

Okay

3,277 reviews

Delta

8.0

Very good

7,910 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

What are the cheapest airlines flying from Harrisburg to San Francisco round-trip?
Cheapflights users have booked flights from Harrisburg to San Francisco round-trip from $309. Other airlines that can offer you cheap pricing are Delta, from $314, and Frontier, from $370. You may be able to fly from Harrisburg to San Francisco for 32% less than the average price by searching for these airlines.
What are the cheapest airlines to fly from Harrisburg to San Francisco one-way?
To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $106. American Airlines flights start at $195 while deals on Delta start at $200 one-way.
Can I find deals for flights from Harrisburg to San Francisco that include hotel bookings?
Yes. In addition to deals on Harrisburg to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Harrisburg to San Francisco?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to San Francisco.
Can I find deals for business class flights from Harrisburg to San Francisco?
Yes. Cheapflights offers flight deals from Harrisburg to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Harrisburg to San Francisco?
Currently, January is the cheapest month in which you can book a flight from Harrisburg to San Francisco (average of $276). Flying from Harrisburg to San Francisco in June is currently the most expensive (average of $393). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Roseville

Mountain View

Santa Cruz

Turlock

South San Francisco

Fairfield

Manteca

Sausalito

Richmond

Watsonville

Hollister

Milpitas

Antioch

Hayward

Vallejo

Newark

Alameda

Sunnyvale

Campbell

Daly City

Browse thousands of different options on Cheapflights for your next trip

Top 3 airlines flying from Harrisburg to San Francisco

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$255	Average$455	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$258	Average$362	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$305	Average$483	FlexibilityNo cancel fee	On-time69%

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$106+ Cheap flights from Harrisburg to San Francisco (MDT - SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/11. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Harrisburg to San Francisco with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Harrisburg to San Francisco are usually found in September or April, booked 22 days in advance, depart on a Saturday or Tuesday and return on a Wednesday

Cheap flight deals from Harrisburg to San Francisco

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Harrisburg to San Francisco

Cheapest flights from Harrisburg to San FranciscoExplore the most affordable flight options available from Harrisburg to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 11, 2025.

Explore the most affordable flight options available from Harrisburg to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 11, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Harrisburg to San Francisco that are best for you.

Compare providers for flights from Harrisburg to San Francisco

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Harrisburg to San Francisco in April.

Best time to book a flight from Harrisburg to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Harrisburg with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to San Francisco

How far ahead should I book a flight from Harrisburg to San Francisco?

Use this chart to determine the optimal time to book a round-trip flight from Harrisburg to San Francisco. Price data was last updated on April 4, 2025.

What is the cheapest month to book a flight from Harrisburg to San Francisco?

What is the cheapest time of day to fly from MDT to SFO?

Find hourly flight availability from Harrisburg to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 11, 2025.

Rainfall in San Francisco by month

Plan your trip to San Francisco by taking into account the average rainfall totals by month.

Temperature in San Francisco by month

Plan your trip to San Francisco by taking into account the average temperature totals by month.

Reviews of airlines servicing San Francisco

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Harrisburg to San Francisco round-trip?

What are the cheapest airlines to fly from Harrisburg to San Francisco one-way?

Can I find deals for flights from Harrisburg to San Francisco that include hotel bookings?

How can I find direct flights from Harrisburg to San Francisco?

Can I find deals for business class flights from Harrisburg to San Francisco?

What is the cheapest month to book a flight from Harrisburg to San Francisco?

Traveling to a place near Harrisburg?

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Alternative routes for Harrisburg to San Francisco

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Top 3 airlines flying from Harrisburg to San Francisco

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Cheapest flights from Harrisburg to San Francisco
Explore the most affordable flight options available from Harrisburg to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 11, 2025.