What are the cheapest airlines to fly from Florida Keys to San Francisco one-way?

For one-way options, check prices for Frontier. According to our data, you can fly for as low as $118. Users have also found prices from $119 and $120 on United Airlines and American Airlines, respectively.

What is the cheapest month to book a flight from Florida Keys to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Florida Keys to San Francisco (average of $276). Flying from Florida Keys to San Francisco in June is currently the most expensive (average of $398). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How far in advance should I book a flight from Florida Keys to San Francisco?

When searching for a good deal, it’s best to be prepared for potential fluctuations in price. We recommend booking at least 57 days in advance, which can save you up to 50% on flights from Florida Keys to San Francisco compared to booking the week you need them. Waiting 57 days out may not be for everyone, so we have options available for flights within the next two weeks, with the lowest price starting at $304. For sooner than that we have options available in the next 3 days from $420.

What is the cheapest month to fly from Florida Keys to San Francisco?

Our data shows that January tends to be the cheapest month to fly to San Francisco from Florida Keys. Users have commonly found prices around $338 for the month, but tickets can be as low as $148. Due to multiple factors, prepare for potentially higher prices in June.

What airport do you fly into for flights to San Francisco from Florida Keys?

Most people fly into San Francisco (SFO) if they book a flight to San Francisco from Florida Keys. San Francisco is conveniently located just 11.8 mi from San Francisco’s city center.

Can I find deals for flights from Florida Keys to San Francisco that include hotel bookings?

Yes. In addition to deals on Florida Keys to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Florida Keys to San Francisco?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florida Keys to San Francisco.

Can I find deals for business class flights from Florida Keys to San Francisco?

Yes. Cheapflights offers flight deals from Florida Keys to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$118+ Flights from Florida Keys to San Francisco

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Cheap flight deals from Florida Keys to San Francisco

Most accurate provider	FlightHub 3 stars
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Round-trip from	$218 (United Airlines)
One-way from	$118 (Cheapflightsfares)

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Cheapest flights from Florida Keys to San Francisco
Explore the most affordable flight options available from Florida Keys to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 28, 2025.

Sat 5/39:30 amMIA - SFO

1 stop11h 12mUnited Airlines

Wed 5/710:47 pmSFO - MIA

Nonstop5h 42mUnited Airlines

Deal found 3/27

$218

Tue 4/227:30 pmMIA - SFO

Nonstop6h 24mAmerican Airlines

Thu 5/81:20 pmSFO - MIA

Nonstop5h 31mAmerican Airlines

Deal found 3/27

$228

Thu 5/13:55 pmMIA - SFO

1 stop9h 27mFrontier

Sun 5/412:11 amSFO - MIA

1 stop13h 11mFrontier

Deal found 3/27

$238

Sat 4/195:05 amMIA - SFO

1 stop10h 20mSouthwest

Sat 4/261:15 pmSFO - MIA

1 stop7h 35mSouthwest

Deal found 3/27

$249

Wed 8/136:20 pmMIA - SFO

1 stop17h 56mAlaska Airlines

Tue 8/198:49 pmSFO - MIA

1 stop17h 17mAlaska Airlines

Deal found 3/27

$256

Thu 5/83:17 pmEYW - SFO

1 stop8h 38mAmerican Airlines

Sat 5/1012:21 amSFO - EYW

1 stop8h 49mAmerican Airlines

Deal found 3/27

$257

Sat 8/167:00 amMIA - SFO

1 stop10h 21mDelta

Sat 8/236:00 amSFO - MIA

1 stop8h 39mDelta

Deal found 3/27

$257

Sat 5/317:00 amMIA - SFO

1 stop10h 31mJetBlue

Sun 6/16:00 amSFO - MIA

1 stop14h 13mJetBlue

Deal found 3/27

$292

Thu 4/106:25 amMIA - SFO

1 stop21h 19mMultiple Airlines

Mon 4/2112:43 amSFO - MIA

1 stop7h 41mMultiple Airlines

Deal found 3/27

$336

Thu 4/174:04 pmEYW - SFO

1 stop11h 11mUnited Airlines

Fri 4/2510:46 pmSFO - EYW

1 stop9h 29mUnited Airlines

Deal found 3/26

$356

Thu 4/177:00 amEYW - SFO

2 stops15h 57mDelta

Fri 4/258:54 pmSFO - EYW

2 stops11h 36mDelta

Deal found 3/26

$1,132

Best flights from Florida Keys to San Francisco
Discover carefully curated flight deals from Florida Keys to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 28, 2025.

Sat 5/39:30 amMIA - SFO

1 stop11h 12mUnited Airlines

Wed 5/710:47 pmSFO - MIA

Nonstop5h 42mUnited Airlines

Deal found 3/27

$218

Tue 4/227:30 pmMIA - SFO

Nonstop6h 24mAmerican Airlines

Thu 5/81:20 pmSFO - MIA

Nonstop5h 31mAmerican Airlines

Deal found 3/27

$228

Tue 4/296:00 amMIA - SFO

1 stop11h 38mFrontier

Tue 5/63:34 pmSFO - MIA

1 stop10h 48mFrontier

Deal found 3/28

$238

Sat 4/195:05 amMIA - SFO

1 stop10h 20mSouthwest

Sat 4/261:15 pmSFO - MIA

1 stop7h 35mSouthwest

Deal found 3/27

$249

Wed 8/136:20 pmMIA - SFO

1 stop17h 56mAlaska Airlines

Tue 8/198:49 pmSFO - MIA

1 stop17h 17mAlaska Airlines

Deal found 3/27

$256

Sat 8/167:00 amMIA - SFO

1 stop10h 21mDelta

Sat 8/236:00 amSFO - MIA

1 stop8h 39mDelta

Deal found 3/27

$257

Sat 5/317:00 amMIA - SFO

1 stop10h 31mJetBlue

Sun 6/16:00 amSFO - MIA

1 stop14h 13mJetBlue

Deal found 3/27

$292

Thu 4/106:25 amMIA - SFO

1 stop21h 19mMultiple Airlines

Mon 4/2112:43 amSFO - MIA

1 stop7h 41mMultiple Airlines

Deal found 3/27

$336

Thu 5/83:17 pmEYW - SFO

1 stop8h 38mAmerican Airlines

Sat 5/1012:21 amSFO - EYW

1 stop8h 49mAmerican Airlines

Deal found 3/27

$257

Thu 4/174:04 pmEYW - SFO

1 stop11h 11mUnited Airlines

Fri 4/2510:46 pmSFO - EYW

1 stop9h 29mUnited Airlines

Deal found 3/26

$356

Thu 4/177:00 amEYW - SFO

2 stops15h 57mDelta

Fri 4/258:54 pmSFO - EYW

2 stops11h 36mDelta

Deal found 3/26

$1,132

Last-minute flights from Florida Keys to San Francisco
Discover last-minute flight deals from Florida Keys to San Francisco. Data last updated March 28, 2025 and is based on user searches.

Wed 4/27:17 amMIA - SFO

Nonstop6h 30mAmerican Airlines

Wed 4/97:39 amSFO - MIA

Nonstop5h 28mAmerican Airlines

Deal found 3/26

$267

Wed 4/25:10 pmMIA - SFO

1 stop8h 48mFrontier

Wed 4/911:58 pmSFO - MIA

1 stop10h 58mFrontier

Deal found 3/26

$278

Wed 4/26:22 amMIA - SFO

2 stops11h 56mUnited Airlines

Wed 4/911:20 pmSFO - MIA

1 stop9h 28mUnited Airlines

Deal found 3/26

$392

Thu 4/38:59 amMIA - SFO

1 stop9h 09mDelta

Mon 4/712:30 amSFO - MIA

1 stop10h 13mDelta

Deal found 3/27

$317

Fri 4/46:45 amMIA - SFO

2 stops10h 20mSouthwest

Wed 4/910:40 amSFO - MIA

1 stop7h 55mSouthwest

Deal found 3/27

$418

Fri 4/410:04 amMIA - SFO

2 stops13h 36mMultiple Airlines

Tue 4/812:08 amSFO - MIA

1 stop11h 49mMultiple Airlines

Deal found 3/27

$10,792

Thu 4/106:25 amMIA - SFO

1 stop21h 19mMultiple Airlines

Tue 4/2210:35 pmSFO - MIA

Nonstop5h 43mMultiple Airlines

Deal found 3/27

$301

Wed 4/167:59 pmMIA - SFO

1 stop15h 59mAlaska Airlines

Sat 4/198:55 pmSFO - MIA

2 stops17h 07mAlaska Airlines

Deal found 3/27

$386

Thu 4/178:50 amMIA - SFO

1 stop9h 02mUnited Airlines

Tue 4/2210:35 pmSFO - MIA

Nonstop5h 43mUnited Airlines

Deal found 3/27

$218

Thu 4/173:02 pmMIA - SFO

1 stop10h 47mFrontier

Tue 4/223:33 pmSFO - MIA

1 stop10h 48mFrontier

Deal found 3/27

$238

Thu 4/174:04 pmEYW - SFO

1 stop11h 11mUnited Airlines

Fri 4/2510:46 pmSFO - EYW

1 stop9h 29mUnited Airlines

Deal found 3/26

$356

Thu 4/177:00 amEYW - SFO

2 stops15h 57mDelta

Fri 4/258:54 pmSFO - EYW

2 stops11h 36mDelta

Deal found 3/26

$1,132

One-way flights from Florida Keys to San Francisco
Search for one-way flight options from Florida Keys to San Francisco. Find affordable one-way fares based on user searches. Data last updated March 28, 2025.

Thu 5/13:55 pmMIA - SFO

1 stop9h 27mFrontier

Deal found 3/27

$118

Thu 4/174:48 pmMIA - SFO

Nonstop6h 27mUnited Airlines

Deal found 3/27

$119

Thu 4/247:30 pmMIA - SFO

Nonstop6h 24mAmerican Airlines

Deal found 3/27

$120

Sat 5/107:25 amMIA - SFO

1 stop9h 04mDelta

Deal found 3/26

$129

Thu 4/36:45 amMIA - SFO

1 stop9h 00mSouthwest

Deal found 3/27

$140

Tue 4/152:28 pmMIA - SFO

2 stops29h 25mMultiple Airlines

Deal found 3/27

$163

Tue 5/276:21 pmMIA - SFO

2 stops21h 18mAlaska Airlines

Deal found 3/27

$202

Sat 6/143:55 pmEYW - SFO

1 stop9h 57mAmerican Airlines

Deal found 3/27

$230

Sat 6/148:45 amEYW - SFO

2 stops17h 49mUnited Airlines

Deal found 3/27

$302

Cheapflights Fare Finder

Use the filters below to find and compare flights from Florida Keys to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Sat 5/3

9:30 am-5:42 pm

1 stop11h 12m

San Francisco

Wed 5/7

10:47 pm-7:29 am

Nonstop5h 42m

$218

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Tue 4/22

7:30 pm-10:54 pm

Nonstop6h 24m

San Francisco

Thu 5/8

1:20 pm-9:51 pm

Nonstop5h 31m

$228

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Thu 5/1

3:55 pm-10:22 pm

1 stop9h 27m

San Francisco

Sun 5/4

12:11 am-4:22 pm

1 stop13h 11m

$238

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Sat 4/19

5:05 am-12:25 pm

1 stop10h 20m

San Francisco

Sat 4/26

1:15 pm-11:50 pm

1 stop7h 35m

$249

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Wed 8/13

6:20 pm-9:16 am

1 stop17h 56m

San Francisco

Tue 8/19

8:49 pm-5:06 pm

1 stop17h 17m

$256

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Sat 8/16

7:00 am-2:21 pm

1 stop10h 21m

San Francisco

Sat 8/23

6:00 am-5:39 pm

1 stop8h 39m

$257

Key WestSan Francisco

EYW - SFO

EYWSFO

Key West

Thu 5/8

3:17 pm-8:55 pm

1 stop8h 38m

San Francisco

Sat 5/10

12:21 am-12:10 pm

1 stop8h 49m

$257

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Sat 5/31

7:00 am-2:31 pm

1 stop10h 31m

San Francisco

Sun 6/1

6:00 am-11:13 pm

1 stop14h 13m

$292

MiamiSan Francisco

MIA - SFO

MIASFO

Miami

Thu 4/10

6:25 am-12:44 am

1 stop21h 19m

San Francisco

Mon 4/21

12:43 am-11:24 am

1 stop7h 41m

$336

Key WestSan Francisco

EYW - SFO

EYWSFO

Key West

Thu 4/17

4:04 pm-12:15 am

1 stop11h 11m

San Francisco

Fri 4/25

10:46 pm-11:15 am

1 stop9h 29m

$356

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/27

Showing 1-10 of 20 results

Best time to book a flight from Florida Keys to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Florida Keys with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florida Keys to San Francisco

What is the cheapest time of day to fly from EOA to SFO?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Florida Keys to San Francisco as you normally would.

Rainfall in San Francisco by month

In terms of precipitation, rainfall in San Francisco ranges from 0.0 - 4.4 inches per month. January is typically the wettest month, when rainfall can reach 4.4 in. July is typically the driest time to visit San Francisco when rainfall is around 0.0 in.

Temperature in San Francisco by month

If weather is an important factor for your trip to San Francisco, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

Reviews of airlines servicing San Francisco

Get a feel of what it's like to fly with Southwest, Alaska Airlines and Delta from Florida Keys to San Francisco by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.1

Very good

4,273 reviews

Reviews

1 / 20

10.0

Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.

Southwest

8.1

Very good

4,273 reviews

Southwest

8.1

Very good

4,273 reviews

Reviews

1 / 20

10.0

Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.

Alaska Airlines

8.0

Very good

9,798 reviews

Southwest

8.1

Very good

4,273 reviews

Reviews

1 / 20

10.0

Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.

Delta

8.0

Very good

7,896 reviews

Southwest

8.1

Very good

4,273 reviews

Reviews

1 / 20

10.0

Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.

United Airlines

7.4

Good

8,603 reviews

Southwest

8.1

Very good

4,273 reviews

Reviews

1 / 20

10.0

Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.

JetBlue

7.3

Good

2,923 reviews

Southwest

8.1

Very good

4,273 reviews

Reviews

1 / 20

10.0

Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.

Related info for your journey

What airport do you fly into for flights to San Francisco from Florida Keys?
Most people fly into San Francisco (SFO) if they book a flight to San Francisco from Florida Keys. San Francisco is conveniently located just 11.8 mi from San Francisco’s city center.
What are the cheapest airlines to fly from Florida Keys to San Francisco one-way?
For one-way options, check prices for Frontier. According to our data, you can fly for as low as $118. Users have also found prices from $119 and $120 on United Airlines and American Airlines, respectively.
Can I find deals for flights from Florida Keys to San Francisco that include hotel bookings?
Yes. In addition to deals on Florida Keys to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Florida Keys to San Francisco?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florida Keys to San Francisco.
Can I find deals for business class flights from Florida Keys to San Francisco?
Yes. Cheapflights offers flight deals from Florida Keys to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Florida Keys to San Francisco?
Currently, January is the cheapest month in which you can book a flight from Florida Keys to San Francisco (average of $276). Flying from Florida Keys to San Francisco in June is currently the most expensive (average of $398). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Roseville

Mountain View

Santa Cruz

Turlock

Fairfield

South San Francisco

Manteca

Sausalito

Richmond

Watsonville

Hollister

Milpitas

Antioch

Hayward

Vallejo

Newark

Alameda

Campbell

Daly City

Pacific Grove

Browse thousands of different options on Cheapflights for your next trip

Top airline flying from Florida Keys to San Francisco

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$355	Average$592	FlexibilityNo cancel fee	On-time71%

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$118+ Cheap flights from Florida Keys to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/1. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Florida Keys to San Francisco with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Florida Keys to San Francisco

Keep the following information in mind while searching for Florida Keys to San Francisco flight deals. Data was last updated March 28, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Find flight deals from Florida Keys to San Francisco

Cheapest flights from Florida Keys to San FranciscoExplore the most affordable flight options available from Florida Keys to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 28, 2025.

Explore the most affordable flight options available from Florida Keys to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 28, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Florida Keys to San Francisco that are best for you.

Best time to book a flight from Florida Keys to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Florida Keys with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Florida Keys to San Francisco

What is the cheapest time of day to fly from EOA to SFO?

Find hourly flight availability from Florida Keys to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 28, 2025.

Rainfall in San Francisco by month

Plan your trip to San Francisco by taking into account the average rainfall totals by month.

Temperature in San Francisco by month

Plan your trip to San Francisco by taking into account the average temperature totals by month.

Reviews of airlines servicing San Francisco

Get a feel of what it's like to fly with Southwest, Alaska Airlines and Delta from Florida Keys to San Francisco by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Florida Keys to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to San Francisco from Florida Keys?

What are the cheapest airlines to fly from Florida Keys to San Francisco one-way?

Can I find deals for flights from Florida Keys to San Francisco that include hotel bookings?

How can I find direct flights from Florida Keys to San Francisco?

Can I find deals for business class flights from Florida Keys to San Francisco?

What is the cheapest month to book a flight from Florida Keys to San Francisco?

Traveling to a place near Florida Keys?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Florida Keys to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from Florida Keys to San Francisco

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Cheapest flights from Florida Keys to San Francisco
Explore the most affordable flight options available from Florida Keys to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 28, 2025.