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$71+ Cheap flights from Knoxville (TYS) to San Francisco Bay Area

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/10. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — SFO
Feb 25 — Mar 41
Tue 2/25
Tue 3/4
1 adult, Economy
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Cheap flight deals from Knoxville to San Francisco Bay Area

Keep the following information in mind while searching for Knoxville to San Francisco Bay Area flight deals. Data was last updated February 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$170
(Frontier)

One-way from

$71
(Frontier)

Popular in

July

Cheapest in

September

Average price

$373
Provider with most accurate pricing for Knoxville McGhee Tyson-San Francisco flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-San Francisco flights.
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From Knoxville McGhee Tyson to San Francisco Bay Area
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One-way flight from Knoxville McGhee Tyson to San Francisco Bay Area
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Highest demand for flights based on searches. 17% potential increase in price ($94 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($22 potential savings vs. average RT price).
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Average for round-trip flights in February 2025
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Find flight deals from Knoxville to San Francisco Bay Area

Cheapest flights from Knoxville to San Francisco Bay Area
Explore the most affordable flight options available from Knoxville to San Francisco Bay Area. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

This Frontier deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/34:31 pmTYS - SFO
1 stop11h 13mFrontier
Thu 4/106:00 amSFO - TYS
1 stop6h 41mFrontier
Deal found 2/19$170
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/15:51 amTYS - SJC
1 stop8h 44mAmerican Airlines
Mon 4/72:19 pmSJC - TYS
1 stop6h 36mAmerican Airlines
Deal found 2/20$279
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/17:00 amTYS - SJC
2 stops9h 35mUnited Airlines
Mon 4/76:27 pmSJC - TYS
2 stops12h 38mUnited Airlines
Deal found 2/20$290
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/16:30 pmTYS - SJC
2 stops22h 04mMultiple Airlines
Mon 4/77:54 pmSJC - TYS
3 stops19h 38mMultiple Airlines
Deal found 2/20$296
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/62:55 pmTYS - SFO
1 stop8h 30mUnited Airlines
Wed 9/105:15 amSFO - TYS
1 stop6h 24mUnited Airlines
Deal found 2/20$305
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/195:00 pmTYS - SFO
1 stop10h 22mDelta
Wed 3/262:19 pmSFO - TYS
1 stop6h 23mDelta
Deal found 2/20$309
This American Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/256:18 pmTYS - SFO
1 stop9h 12mAmerican Airlines
Mon 4/2810:19 pmSFO - TYS
1 stop9h 19mAmerican Airlines
Deal found 2/18$339
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/36:00 amTYS - SFO
2 stops28h 42mMultiple Airlines
Thu 4/107:00 amSFO - TYS
2 stops25h 32mMultiple Airlines
Deal found 2/19$353
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/41:43 pmTYS - OAK
3 stops32h 49mMultiple Airlines
Fri 5/910:06 amOAK - TYS
1 stop8h 53mMultiple Airlines
Deal found 2/20$355
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/266:05 pmTYS - SJC
2 stops8h 43mDelta
Mon 6/306:30 amSJC - TYS
1 stop7h 10mDelta
Deal found 2/19$444
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/105:00 pmTYS - OAK
2 stops9h 46mDelta
Tue 4/155:10 pmOAK - TYS
2 stops13h 11mDelta
Deal found 2/20$629
This Alaska Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/43:09 pmTYS - SJC
1 stop9h 19mAlaska Airlines
Fri 5/92:15 pmSJC - TYS
1 stop6h 44mAlaska Airlines
Deal found 2/20$749

Find flights from Knoxville to San Francisco Bay Area within your budget

Customize your flight search to find flights from Knoxville to San Francisco Bay Area that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.

Fly from

Knoxville

Fly to

San Francisco Bay Area

Route

Depart

Return

Price

KnoxvilleSan Francisco

TYS - SFO

TYSSFO

Knoxville McGhee Tyson

Thu 4/3

4:31 pm-12:44 am

1 stop11h 13m

San Francisco

Thu 4/10

6:00 am-3:41 pm

1 stop6h 41m

$170

KnoxvilleSan Jose

TYS - SJC

TYSSJC

Knoxville McGhee Tyson

Tue 4/1

5:51 am-11:35 am

1 stop8h 44m

San Jose

Mon 4/7

2:19 pm-11:55 pm

1 stop6h 36m

$279

KnoxvilleSan Jose

TYS - SJC

TYSSJC

Knoxville McGhee Tyson

Tue 4/1

7:00 am-1:35 pm

2 stops9h 35m

San Jose

Mon 4/7

6:27 pm-10:05 am

2 stops12h 38m

$290

KnoxvilleSan Jose

TYS - SJC

TYSSJC

Knoxville McGhee Tyson

Tue 4/1

6:30 pm-1:34 pm

2 stops22h 04m

San Jose

Mon 4/7

7:54 pm-6:32 pm

3 stops19h 38m

$296

KnoxvilleSan Francisco

TYS - SFO

TYSSFO

Knoxville McGhee Tyson

Wed 3/19

5:00 pm-12:22 am

1 stop10h 22m

San Francisco

Wed 3/26

2:19 pm-11:42 pm

1 stop6h 23m

$309

KnoxvilleSan Francisco

TYS - SFO

TYSSFO

Knoxville McGhee Tyson

Fri 4/25

6:18 pm-12:30 am

1 stop9h 12m

San Francisco

Mon 4/28

10:19 pm-10:38 am

1 stop9h 19m

$339

KnoxvilleSan Francisco

TYS - SFO

TYSSFO

Knoxville McGhee Tyson

Thu 4/3

6:00 am-7:42 am

2 stops28h 42m

San Francisco

Thu 4/10

7:00 am-11:32 am

2 stops25h 32m

$353

KnoxvilleOakland

TYS - OAK

TYSOAK

Knoxville McGhee Tyson

Sun 5/4

1:43 pm-7:32 pm

3 stops32h 49m

Oakland

Fri 5/9

10:06 am-9:59 pm

1 stop8h 53m

$355

KnoxvilleSan Francisco

TYS - SFO

TYSSFO

Knoxville McGhee Tyson

Tue 4/1

7:00 am-7:52 pm

2 stops15h 52m

San Francisco

Mon 4/7

10:44 pm-10:05 am

1 stop8h 21m

$434

KnoxvilleSan Jose

TYS - SJC

TYSSJC

Knoxville McGhee Tyson

Thu 6/26

6:05 pm-11:48 pm

2 stops8h 43m

San Jose

Mon 6/30

6:30 am-4:40 pm

1 stop7h 10m

$444

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/19

Showing 1-10 of 25 results
1
2
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Best time to book a flight from Knoxville to San Francisco Bay Area

Have a flexible travel schedule? Discover the best time to fly to San Francisco Bay Area from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Knoxville to San Francisco Bay Area

Get recent, data-driven insights about flights from Knoxville to San Francisco Bay Area including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Knoxville to San Francisco Bay Area?

Currently, January is the cheapest month in which you can book a flight from Knoxville to San Francisco Bay Area (average of $276). Flying from Knoxville to San Francisco Bay Area in June is currently the most expensive (average of $403). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to XIH?

Find hourly flight availability from Knoxville to San Francisco Bay Area. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 20, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Knoxville to San Francisco Bay Area as you normally would.

Rainfall in San Francisco Bay Area by month

Plan your trip to San Francisco Bay Area by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in San Francisco Bay Area ranges from 0.0 - 4.4 inches per month. January is typically the wettest month, when rainfall can reach 4.4 in. July is typically the driest time to visit San Francisco Bay Area when rainfall is around 0.0 in.

Temperature in San Francisco Bay Area by month

Plan your trip to San Francisco Bay Area by taking into account the average temperature totals by month.

If weather is an important factor for your trip to San Francisco Bay Area, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

Reviews of airlines servicing San Francisco Bay Area

Get insights into the airlines that provide service to San Francisco Bay Area. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco Bay Area. Reviews last updated February 20, 2025.
Read reviews from past customers who have flown Alaska Airlines, Delta and United Airlines from Knoxville to San Francisco Bay Area. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
9,692 reviews

Comfort

7.9

Food

7.1

Entertainment

7.1

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Seleste,Dec 2024

FAT - SAN

The attention and efficiency of the staff and the good handling of the pilot

Alaska Airlines
8.0
Very good
9,692 reviews
Alaska Airlines
8.0
Very good
9,692 reviews

Comfort

7.9

Food

7.1

Entertainment

7.1

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Seleste,Dec 2024

FAT - SAN

The attention and efficiency of the staff and the good handling of the pilot

Delta
8.0
Very good
8,220 reviews
Alaska Airlines
8.0
Very good
9,692 reviews

Comfort

7.9

Food

7.1

Entertainment

7.1

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Seleste,Dec 2024

FAT - SAN

The attention and efficiency of the staff and the good handling of the pilot

United Airlines
7.4
Good
8,766 reviews
Alaska Airlines
8.0
Very good
9,692 reviews

Comfort

7.9

Food

7.1

Entertainment

7.1

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Seleste,Dec 2024

FAT - SAN

The attention and efficiency of the staff and the good handling of the pilot

American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
9,692 reviews

Comfort

7.9

Food

7.1

Entertainment

7.1

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Seleste,Dec 2024

FAT - SAN

The attention and efficiency of the staff and the good handling of the pilot

Frontier
6.0
Okay
3,355 reviews
Alaska Airlines
8.0
Very good
9,692 reviews

Comfort

7.9

Food

7.1

Entertainment

7.1

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Seleste,Dec 2024

FAT - SAN

The attention and efficiency of the staff and the good handling of the pilot

Related info for your journey

Find useful and relevant information for your journey from Knoxville to San Francisco Bay Area. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to San Francisco Bay Area?

    Located just 11.3 mi from the city center, Knoxville McGhee Tyson (TYS) is the airport most travelers will use when flying to San Francisco Bay Area from Knoxville.

  • What are the cheapest airlines to fly from Knoxville to San Francisco Bay Area one-way?

    $71 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on American Airlines and United Airlines, with prices starting from $246 and $279, respectively.

  • What are the most popular routes from Knoxville to San Francisco Bay Area?

    Most travelers choose Knoxville McGhee Tyson - San Francisco, Knoxville McGhee Tyson - Oakland or Knoxville McGhee Tyson - San Jose when deciding on the best route from Knoxville to San Francisco Bay Area.

  • Can I find deals for flights from Knoxville to San Francisco Bay Area that include hotel bookings?

    Yes. In addition to deals on Knoxville to San Francisco Bay Area flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to San Francisco Bay Area?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to San Francisco Bay Area.

  • Can I find deals for business class flights from Knoxville to San Francisco Bay Area?

    Yes. Cheapflights offers flight deals from Knoxville to San Francisco Bay Area by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to San Francisco Bay Area?

    Currently, January is the cheapest month in which you can book a flight from Knoxville to San Francisco Bay Area (average of $276). Flying from Knoxville to San Francisco Bay Area in June is currently the most expensive (average of $403). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Knoxville to San Francisco Bay Area

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Top 4 airlines flying from Knoxville to San Francisco Bay Area

Discover the top 4 airlines that operate flights from Knoxville to San Francisco Bay Area. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$155Average$194FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$248Average$553FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$282Average$534FlexibilityNo cancel feeOn-time71%
DeltaCheapest$298Average$535FlexibilityNo cancel feeOn-timeN/A
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