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$139+ Cheap flights from Knoxville (TYS) to San Francisco Bay Area

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/21. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — SFO
Apr 22 — Apr 291
Tue 4/22
Tue 4/29
1 adult, Economy
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Cheap flight deals from Knoxville to San Francisco Bay Area

Keep the following information in mind while searching for Knoxville to San Francisco Bay Area flight deals. Data was last updated April 17, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$251
(American Airlines)

One-way from

$139
(Delta)

Popular in

July

Cheapest in

January

Average price

$430
Provider with most accurate pricing for Knoxville McGhee Tyson-San Francisco flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-San Francisco flights.
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From Knoxville McGhee Tyson to San Francisco Bay Area
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One-way flight from Knoxville McGhee Tyson to San Francisco Bay Area
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Highest demand for flights based on searches. 18% potential increase in price ($99 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($22 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Knoxville to San Francisco Bay Area

Cheapest flights from Knoxville to San Francisco Bay Area
Explore the most affordable flight options available from Knoxville to San Francisco Bay Area. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.

This Frontier deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/225:30 pmTYS - SFO
1 stop9h 39mFrontier
Thu 5/296:35 amSFO - TYS
1 stop7h 00mFrontier
Deal found 4/17$238
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/135:20 amTYS - SJC
1 stop8h 55mAmerican Airlines
Tue 5/206:00 amSJC - TYS
1 stop8h 31mAmerican Airlines
Deal found 4/16$251
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/114:11 pmTYS - SJC
1 stop6h 44mDelta
Sun 6/1510:25 pmSJC - TYS
1 stop8h 28mDelta
Deal found 4/16$293
This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/277:00 amTYS - SFO
1 stop9h 35mUnited Airlines
Wed 9/35:15 amSFO - TYS
1 stop6h 24mUnited Airlines
Deal found 4/16$304
This Mytrip deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/910:59 amTYS - SFO
1 stop27h 09mMultiple Airlines
Sun 6/1511:59 pmSFO - TYS
1 stop13h 12mMultiple Airlines
Deal found 4/16$323
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/211:55 amTYS - SFO
1 stop9h 12mDelta
Tue 5/610:45 pmSFO - TYS
1 stop7h 55mDelta
Deal found 4/16$339
This Mytrip deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/11:43 pmTYS - OAK
2 stops20h 06mMultiple Airlines
Mon 5/57:46 amOAK - TYS
1 stop11h 13mMultiple Airlines
Deal found 4/16$367
This Mytrip deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/113:10 pmTYS - SJC
2 stops24h 16mMultiple Airlines
Sun 6/156:00 amSJC - TYS
3 stops31h 11mMultiple Airlines
Deal found 4/16$382
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/232:56 pmTYS - SFO
1 stop8h 23mAmerican Airlines
Sat 5/2412:21 amSFO - TYS
1 stop7h 07mAmerican Airlines
Deal found 4/17$394
This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/65:35 pmTYS - SJC
1 stop8h 19mUnited Airlines
Sat 5/101:11 pmSJC - TYS
1 stop7h 35mUnited Airlines
Deal found 4/16$420
This Alaska Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/67:00 amTYS - SJC
1 stop9h 25mAlaska Airlines
Sat 5/105:56 pmSJC - TYS
2 stops13h 48mAlaska Airlines
Deal found 4/16$431
This Alaska Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/13:09 pmTYS - SFO
1 stop9h 48mAlaska Airlines
Mon 5/511:48 amSFO - TYS
1 stop7h 19mAlaska Airlines
Deal found 4/16$469

Cheapflights Fare Finder

Customize your flight search to find flights from Knoxville to San Francisco Bay Area that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
Use the filters below to find and compare flights from Knoxville to San Francisco Bay Area that are best for you.

Fly from

Knoxville

Fly to

San Francisco Bay Area

Route

Depart

Return

Price

KnoxvilleSan Jose

TYS - SJC

TYSSJC

Knoxville McGhee Tyson

Tue 5/13

5:20 am-11:15 am

1 stop8h 55m

San Jose

Tue 5/20

6:00 am-5:31 pm

1 stop8h 31m

$251

KnoxvilleSan Jose

TYS - SJC

TYSSJC

Knoxville McGhee Tyson

Wed 6/11

4:11 pm-7:55 pm

1 stop6h 44m

San Jose

Sun 6/15

10:25 pm-9:53 am

1 stop8h 28m

$293

KnoxvilleSan Francisco

TYS - SFO

TYSSFO

Knoxville McGhee Tyson

Thu 5/8

4:14 pm-9:05 pm

1 stop7h 51m

San Francisco

Fri 5/16

10:50 pm-10:15 am

1 stop8h 25m

$309

KnoxvilleSan Francisco

TYS - SFO

TYSSFO

Knoxville McGhee Tyson

Mon 6/9

10:59 am-11:08 am

1 stop27h 09m

San Francisco

Sun 6/15

11:59 pm-4:11 pm

1 stop13h 12m

$323

KnoxvilleSan Francisco

TYS - SFO

TYSSFO

Knoxville McGhee Tyson

Fri 5/2

11:55 am-6:07 pm

1 stop9h 12m

San Francisco

Tue 5/6

10:45 pm-9:40 am

1 stop7h 55m

$339

KnoxvilleSan Francisco

TYS - SFO

TYSSFO

Knoxville McGhee Tyson

Thu 5/15

6:28 pm-12:22 am

1 stop8h 54m

San Francisco

Mon 5/19

12:24 am-11:43 am

1 stop8h 19m

$364

KnoxvilleOakland

TYS - OAK

TYSOAK

Knoxville McGhee Tyson

Thu 5/1

1:43 pm-6:49 am

2 stops20h 06m

Oakland

Mon 5/5

7:46 am-9:59 pm

1 stop11h 13m

$367

KnoxvilleSan Jose

TYS - SJC

TYSSJC

Knoxville McGhee Tyson

Wed 6/11

3:10 pm-12:26 pm

2 stops24h 16m

San Jose

Sun 6/15

6:00 am-4:11 pm

3 stops31h 11m

$382

KnoxvilleSan Jose

TYS - SJC

TYSSJC

Knoxville McGhee Tyson

Tue 5/6

5:35 pm-10:54 pm

1 stop8h 19m

San Jose

Sat 5/10

1:11 pm-11:46 pm

1 stop7h 35m

$420

KnoxvilleSan Jose

TYS - SJC

TYSSJC

Knoxville McGhee Tyson

Tue 5/6

7:00 am-1:25 pm

1 stop9h 25m

San Jose

Sat 5/10

5:56 pm-10:44 am

2 stops13h 48m

$431

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/16

Showing 1-10 of 24 results
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Best time to book a flight from Knoxville to San Francisco Bay Area

Have a flexible travel schedule? Discover the best time to fly to San Francisco Bay Area from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to San Francisco Bay Area

What is the cheapest month to book a flight from Knoxville to San Francisco Bay Area?

Currently, January is the cheapest month in which you can book a flight from Knoxville to San Francisco Bay Area (average of $276). Flying from Knoxville to San Francisco Bay Area in June is currently the most expensive (average of $393). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to XIH?

Find hourly flight availability from Knoxville to San Francisco Bay Area. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 17, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Knoxville to San Francisco Bay Area as you normally would.

Rainfall in San Francisco Bay Area by month

Plan your trip to San Francisco Bay Area by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in San Francisco Bay Area ranges from 0.0 - 4.4 inches per month. January is typically the wettest month, when rainfall can reach 4.4 in. July is typically the driest time to visit San Francisco Bay Area when rainfall is around 0.0 in.

Temperature in San Francisco Bay Area by month

Plan your trip to San Francisco Bay Area by taking into account the average temperature totals by month.

If weather is an important factor for your trip to San Francisco Bay Area, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

Reviews of airlines servicing San Francisco Bay Area

Get insights into the airlines that provide service to San Francisco Bay Area. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco Bay Area. Reviews last updated April 17, 2025.
Read reviews from past customers who have flown Alaska Airlines, Delta and United Airlines from Knoxville to San Francisco Bay Area. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
9,882 reviews

Entertainment

7.1

Boarding

8.2

Comfort

7.9

Overall

8.0

Crew

8.5

Food

7.1

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
Alaska Airlines
8.0
Very good
9,882 reviews
Alaska Airlines
8.0
Very good
9,882 reviews

Entertainment

7.1

Boarding

8.2

Comfort

7.9

Overall

8.0

Crew

8.5

Food

7.1

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
Delta
8.0
Very good
7,917 reviews
Alaska Airlines
8.0
Very good
9,882 reviews

Entertainment

7.1

Boarding

8.2

Comfort

7.9

Overall

8.0

Crew

8.5

Food

7.1

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
United Airlines
7.4
Good
8,667 reviews
Alaska Airlines
8.0
Very good
9,882 reviews

Entertainment

7.1

Boarding

8.2

Comfort

7.9

Overall

8.0

Crew

8.5

Food

7.1

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
9,882 reviews

Entertainment

7.1

Boarding

8.2

Comfort

7.9

Overall

8.0

Crew

8.5

Food

7.1

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >

Related info for your journey

Find useful and relevant information for your journey from Knoxville to San Francisco Bay Area. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to San Francisco Bay Area?

    Located just 11.3 mi from the city center, Knoxville McGhee Tyson (TYS) is the airport most travelers will use when flying to San Francisco Bay Area from Knoxville.

  • What are the cheapest airlines to fly from Knoxville to San Francisco Bay Area one-way?

    $139 is the cheapest one-way deal found within the past few days, from Delta. You may also be able to find cheap deals on Alaska Airlines and American Airlines, with prices starting from $220 and $246, respectively.

  • What are the most popular routes from Knoxville to San Francisco Bay Area?

    Most travelers choose Knoxville McGhee Tyson - San Francisco, Knoxville McGhee Tyson - San Jose or Knoxville McGhee Tyson - Oakland when deciding on the best route from Knoxville to San Francisco Bay Area.

  • Can I find deals for flights from Knoxville to San Francisco Bay Area that include hotel bookings?

    Yes. In addition to deals on Knoxville to San Francisco Bay Area flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to San Francisco Bay Area?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to San Francisco Bay Area.

  • Can I find deals for business class flights from Knoxville to San Francisco Bay Area?

    Yes. Cheapflights offers flight deals from Knoxville to San Francisco Bay Area by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to San Francisco Bay Area?

    Currently, January is the cheapest month in which you can book a flight from Knoxville to San Francisco Bay Area (average of $276). Flying from Knoxville to San Francisco Bay Area in June is currently the most expensive (average of $393). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Knoxville to San Francisco Bay Area

Discover the top 4 airlines that operate flights from Knoxville to San Francisco Bay Area. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$155Average$190FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$248Average$536FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$281Average$527FlexibilityNo cancel feeOn-time71%
DeltaCheapest$287Average$513FlexibilityNo cancel feeOn-timeN/A

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