$84+ Cheap flights from South Carolina to San Diego (SAN)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/29. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — SAN
Apr 8 — Apr 151
1 adult, Economy
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Find cheap flights from South Carolina to San Diego with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from South Carolina to San Diego
Keep the following information in mind while searching for South Carolina to San Diego flight deals. Data was last updated April 3, 2025.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $200 (Booking.com) |
One-way from | $84 (CheapOair) |
Popular in | May |
Cheapest in | September |
Average price | $538 |
Find flight deals from South Carolina to San Diego
Cheapest flights from South Carolina to San DiegoExplore the most affordable flight options available from South Carolina to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 3, 2025.
Explore the most affordable flight options available from South Carolina to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 3, 2025.
This Booking.com deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/234:20 pmCLT - SAN
2 stops18h 14mSpirit Airlines
Tue 4/299:08 pmSAN - CLT
2 stops9h 28mSpirit Airlines
Deal found 4/2![Spirit Airlines logo]()
$200
This American Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/256:34 pmCAE - SAN
1 stop6h 59mAmerican Airlines
Sat 11/812:48 pmSAN - CAE
1 stop5h 55mAmerican Airlines
Deal found 4/3![American Airlines logo]()
$217
This Booking.com deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/234:20 pmCLT - SAN
2 stops18h 14mMultiple Airlines
Tue 4/296:25 amSAN - CLT
1 stop6h 37mMultiple Airlines
Deal found 4/2![Multiple Airlines logo]()
$223
This Frontier deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/264:52 pmCLT - SAN
1 stop10h 22mFrontier
Tue 4/296:25 amSAN - CLT
1 stop6h 37mFrontier
Deal found 4/2![Frontier logo]()
$238
This JetBlue deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2512:30 pmCHS - SAN
1 stop10h 51mJetBlue
Sat 5/38:30 pmSAN - CHS
1 stop11h 27mJetBlue
Deal found 4/2![JetBlue logo]()
$253
This Mytrip deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/210:32 amCHS - SAN
2 stops17h 10mSpirit Airlines
Tue 5/69:08 pmSAN - CHS
2 stops32h 30mSpirit Airlines
Deal found 4/1![Spirit Airlines logo]()
$255
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/177:14 pmCHS - SAN
1 stop7h 29mAmerican Airlines
Sat 5/2411:21 amSAN - CHS
1 stop8h 34mAmerican Airlines
Deal found 4/1![American Airlines logo]()
$271
This Mytrip deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/811:24 amMYR - SAN
3 stops35h 29mSpirit Airlines
Mon 5/126:58 pmSAN - MYR
2 stops13h 01mSpirit Airlines
Deal found 4/1![Spirit Airlines logo]()
$277
This Booking.com deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/237:30 pmCHS - SAN
2 stops15h 04mMultiple Airlines
Sat 4/266:05 pmSAN - CHS
1 stop15h 38mMultiple Airlines
Deal found 4/2![Multiple Airlines logo]()
$281
This United Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/34:12 pmGSP - SAN
1 stop8h 10mUnited Airlines
Sat 5/1010:25 pmSAN - GSP
1 stop9h 18mUnited Airlines
Deal found 4/1![United Airlines logo]()
$287
This Delta deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/43:00 pmCAE - SAN
1 stop7h 55mDelta
Wed 7/96:20 amSAN - CAE
1 stop7h 13mDelta
Deal found 4/2![Delta logo]()
$297
This Delta deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/117:59 pmAGS - SAN
1 stop6h 43mDelta
Wed 5/141:58 pmSAN - AGS
1 stop6h 55mDelta
Deal found 4/2![Delta logo]()
$297
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 3, 2025.
Use the filters below to find and compare flights from South Carolina to San Diego that are best for you.
Fly from
South Carolina
Fly to
San Diego
Route
Depart
Return
Price
CharlotteSan Diego
CLT - SAN
CLTSAN
Charlotte Douglas
Wed 4/23
4:20 pm-7:34 am
2 stops18h 14m
San Diego
Tue 4/29
9:08 pm-9:36 am
2 stops9h 28m
$200
ColumbiaSan Diego
CAE - SAN
CAESAN
Columbia Metropolitan
Sat 5/17
7:00 am-10:59 am
1 stop6h 59m
San Diego
Wed 6/4
9:45 pm-8:25 am
1 stop7h 40m
$217
CharlotteSan Diego
CLT - SAN
CLTSAN
Charlotte Douglas
Wed 4/23
4:20 pm-7:34 am
2 stops18h 14m
San Diego
Tue 4/29
6:25 am-4:02 pm
1 stop6h 37m
$223
CharlotteSan Diego
CLT - SAN
CLTSAN
Charlotte Douglas
Sat 4/26
4:52 pm-12:14 am
1 stop10h 22m
San Diego
Tue 4/29
6:25 am-4:02 pm
1 stop6h 37m
$238
CharlestonSan Diego
CHS - SAN
CHSSAN
Charleston
Fri 4/25
12:30 pm-8:21 pm
1 stop10h 51m
San Diego
Sat 5/3
8:30 pm-10:57 am
1 stop11h 27m
$253
CharlestonSan Diego
CHS - SAN
CHSSAN
Charleston
Fri 5/2
10:32 am-12:42 am
2 stops17h 10m
San Diego
Tue 5/6
9:08 pm-8:38 am
2 stops32h 30m
$255
CharlestonSan Diego
CHS - SAN
CHSSAN
Charleston
Sat 5/17
11:43 am-7:16 pm
1 stop10h 33m
San Diego
Sat 5/24
11:21 am-10:55 pm
1 stop8h 34m
$271
Myrtle BeachSan Diego
MYR - SAN
MYRSAN
Myrtle Beach Intl
Thu 5/8
11:24 am-7:53 pm
3 stops35h 29m
San Diego
Mon 5/12
6:58 pm-10:59 am
2 stops13h 01m
$277
CharlestonSan Diego
CHS - SAN
CHSSAN
Charleston
Wed 4/23
7:30 pm-7:34 am
2 stops15h 04m
San Diego
Sat 4/26
6:05 pm-12:43 pm
1 stop15h 38m
$281
GreenvilleSan Diego
GSP - SAN
GSPSAN
Greenville
Sat 5/3
4:12 pm-9:22 pm
1 stop8h 10m
San Diego
Sat 5/10
10:25 pm-10:43 am
1 stop9h 18m
$287
Showing 1-10 of 60 results
Best time to book a flight from South Carolina to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to San Diego
What is the cheapest month to book a flight from South Carolina to San Diego?
Currently, August is the cheapest month in which you can book a flight from South Carolina to San Diego (average of $286). Flying from South Carolina to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SC to SAN?
Find hourly flight availability from South Carolina to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 3, 2025.
When flying from South Carolina to San Diego, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
Rainfall in San Diego by month
Plan your trip to San Diego by taking into account the average rainfall totals by month.
In terms of precipitation, rainfall in San Diego ranges from 0.0 - 2.3 inches per month. February is typically the wettest month, when rainfall can reach 2.3 in. July is typically the driest time to visit San Diego when rainfall is around 0.0 in.
Temperature in San Diego by month
Plan your trip to San Diego by taking into account the average temperature totals by month.
If weather is an important factor for your trip to San Diego, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 57.2 F).
Reviews of airlines servicing San Diego
Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated April 3, 2025.
To help decide which airline to fly from South Carolina to San Diego, see what other customers have to say about Breeze Airways, Alaska Airlines and Southwest. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
6.7
Comfort
8.2
Overall
8.1
Boarding
8.3
Crew
8.8
Entertainment
6.6
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Food
6.7
Comfort
8.2
Overall
8.1
Boarding
8.3
Crew
8.8
Entertainment
6.6
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Food
6.7
Comfort
8.2
Overall
8.1
Boarding
8.3
Crew
8.8
Entertainment
6.6
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Food
6.7
Comfort
8.2
Overall
8.1
Boarding
8.3
Crew
8.8
Entertainment
6.6
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Food
6.7
Comfort
8.2
Overall
8.1
Boarding
8.3
Crew
8.8
Entertainment
6.6
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Food
6.7
Comfort
8.2
Overall
8.1
Boarding
8.3
Crew
8.8
Entertainment
6.6
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Related info for your journey
Find useful and relevant information for your journey from South Carolina to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near South Carolina?
Book flights to South Carolina if you plan to visit one of these locationsEl Cajon
Chula Vista
Lemon Grove
National City
Imperial Beach
La Mesa
Alpine
Poway
Santee
Coronado
Borrego Springs
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for South Carolina to San Diego
See prices for flight routes from nearby airports that may be better suited for you.
Top 6 airlines flying from South Carolina to San Diego
Discover the top 6 airlines that operate flights from South Carolina to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 3, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$133 | Average$290 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$163 | Average$333 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$258 | Average$485 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$268 | Average$467 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$306 | Average$455 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$350 | Average$468 | FlexibilityNo cancel fee | On-time63% |