$88+ Cheap flights from South Carolina to San Diego (SAN)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/28. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — SAN
Apr 29 — May 61
1 adult, Economy
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Find cheap flights from South Carolina to San Diego with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from South Carolina to San Diego
Keep the following information in mind while searching for South Carolina to San Diego flight deals. Data was last updated April 24, 2025.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | eDreams 3 stars |
Round-trip from | $198 (Frontier) |
One-way from | $88 (FlightHub) |
Popular in | July |
Cheapest in | September |
Average price | $526 |
Find flight deals from South Carolina to San Diego
Cheapest flights from South Carolina to San DiegoExplore the most affordable flight options available from South Carolina to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2025.
Explore the most affordable flight options available from South Carolina to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2025.
This Frontier deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/255:27 pmCLT - SAN
1 stop9h 32mFrontier
Sun 6/16:25 amSAN - CLT
1 stop7h 09mFrontier
Deal found 4/22![Frontier logo]()
$198
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/256:34 pmCAE - SAN
1 stop6h 59mAmerican Airlines
Sat 11/812:10 pmSAN - CAE
1 stop8h 30mAmerican Airlines
Deal found 4/23![American Airlines logo]()
$217
This CheapOair deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/105:34 pmCLT - SAN
1 stop8h 24mMultiple Airlines
Fri 6/137:31 pmSAN - CLT
1 stop14h 39mMultiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$227
This Cheapflightsfares deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/172:15 pmCLT - SAN
1 stop12h 14mSpirit Airlines
Tue 6/247:31 pmSAN - CLT
1 stop14h 39mSpirit Airlines
Deal found 4/23![Spirit Airlines logo]()
$234
This Southwest deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/34:10 pmCLT - SAN
1 stop8h 35mSouthwest
Mon 9/86:20 amSAN - CLT
1 stop9h 40mSouthwest
Deal found 4/22![Southwest logo]()
$242
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/176:34 amCHS - SAN
1 stop7h 25mAmerican Airlines
Sat 5/247:29 amSAN - CHS
1 stop7h 58mAmerican Airlines
Deal found 4/23![American Airlines logo]()
$271
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/34:45 pmCHS - SAN
2 stops10h 01mUnited Airlines
Tue 6/1011:50 amSAN - CHS
1 stop7h 10mUnited Airlines
Deal found 4/23![United Airlines logo]()
$276
This JetBlue deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1111:00 amCHS - SAN
1 stop10h 58mJetBlue
Fri 7/188:29 pmSAN - CHS
1 stop11h 16mJetBlue
Deal found 4/22![JetBlue logo]()
$287
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/204:12 pmGSP - SAN
1 stop8h 10mUnited Airlines
Tue 5/279:45 pmSAN - GSP
1 stop9h 07mUnited Airlines
Deal found 4/22![United Airlines logo]()
$287
This Mytrip deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/215:32 pmMYR - SAN
2 stops16h 41mSpirit Airlines
Wed 5/286:15 amSAN - MYR
2 stops31h 29mSpirit Airlines
Deal found 4/23![Spirit Airlines logo]()
$296
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/279:40 amCHS - SAN
1 stop9h 06mDelta
Fri 5/306:15 amSAN - CHS
1 stop6h 39mDelta
Deal found 4/23![Delta logo]()
$297
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/182:59 pmCAE - SAN
1 stop9h 36mDelta
Tue 10/2110:40 pmSAN - CAE
1 stop7h 45mDelta
Deal found 4/23![Delta logo]()
$297
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2025.
Use the filters below to find and compare flights from South Carolina to San Diego that are best for you.
Fly from
South Carolina
Fly to
San Diego
Route
Depart
Return
Price
CharlotteSan Diego
CLT - SAN
CLTSAN
Charlotte Douglas
Sun 5/25
5:27 pm-11:59 pm
1 stop9h 32m
San Diego
Sun 6/1
6:25 am-4:34 pm
1 stop7h 09m
$198
CharlotteSan Diego
CLT - SAN
CLTSAN
Charlotte Douglas
Tue 6/10
5:34 pm-10:58 pm
1 stop8h 24m
San Diego
Fri 6/13
7:31 pm-1:10 pm
1 stop14h 39m
$227
CharlotteSan Diego
CLT - SAN
CLTSAN
Charlotte Douglas
Tue 6/17
2:15 pm-11:29 pm
1 stop12h 14m
San Diego
Tue 6/24
7:31 pm-1:10 pm
1 stop14h 39m
$234
CharlestonSan Diego
CHS - SAN
CHSSAN
Charleston
Sat 5/17
6:34 am-10:59 am
1 stop7h 25m
San Diego
Sat 5/24
7:29 am-6:27 pm
1 stop7h 58m
$271
CharlestonSan Diego
CHS - SAN
CHSSAN
Charleston
Tue 6/3
4:45 pm-11:46 pm
2 stops10h 01m
San Diego
Tue 6/10
11:50 am-10:00 pm
1 stop7h 10m
$276
CharlestonSan Diego
CHS - SAN
CHSSAN
Charleston
Fri 7/11
11:00 am-6:58 pm
1 stop10h 58m
San Diego
Fri 7/18
8:29 pm-10:45 am
1 stop11h 16m
$287
GreenvilleSan Diego
GSP - SAN
GSPSAN
Greenville
Tue 5/20
4:12 pm-9:22 pm
1 stop8h 10m
San Diego
Tue 5/27
9:45 pm-9:52 am
1 stop9h 07m
$287
CharlotteSan Diego
CLT - SAN
CLTSAN
Charlotte Douglas
Sat 5/24
6:10 pm-10:55 pm
1 stop7h 45m
San Diego
Sun 5/25
6:50 am-8:00 pm
1 stop10h 10m
$288
ColumbiaSan Diego
CAE - SAN
CAESAN
Columbia Metropolitan
Wed 8/13
4:30 pm-7:52 pm
1 stop6h 22m
San Diego
Sun 8/24
10:46 pm-8:19 am
1 stop6h 33m
$288
Myrtle BeachSan Diego
MYR - SAN
MYRSAN
Myrtle Beach Intl
Wed 5/21
5:32 pm-7:13 am
2 stops16h 41m
San Diego
Wed 5/28
6:15 am-4:44 pm
2 stops31h 29m
$296
Showing 1-10 of 60 results
Best time to book a flight from South Carolina to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to San Diego
What is the cheapest month to book a flight from South Carolina to San Diego?
Currently, August is the cheapest month in which you can book a flight from South Carolina to San Diego (average of $286). Flying from South Carolina to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SC to SAN?
Find hourly flight availability from South Carolina to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 24, 2025.
When flying from South Carolina to San Diego, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
Rainfall in San Diego by month
Plan your trip to San Diego by taking into account the average rainfall totals by month.
In terms of precipitation, rainfall in San Diego ranges from 0.0 - 2.3 inches per month. February is typically the wettest month, when rainfall can reach 2.3 in. July is typically the driest time to visit San Diego when rainfall is around 0.0 in.
Temperature in San Diego by month
Plan your trip to San Diego by taking into account the average temperature totals by month.
If weather is an important factor for your trip to San Diego, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 57.2 F).
Reviews of airlines servicing San Diego
Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated April 24, 2025.
To help decide which airline to fly from South Carolina to San Diego, see what other customers have to say about Breeze Airways, Alaska Airlines and Southwest. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.8
Comfort
8.2
Boarding
8.3
Food
6.7
Overall
8.1
Entertainment
6.7
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Crew
8.8
Comfort
8.2
Boarding
8.3
Food
6.7
Overall
8.1
Entertainment
6.7
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Crew
8.8
Comfort
8.2
Boarding
8.3
Food
6.7
Overall
8.1
Entertainment
6.7
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Crew
8.8
Comfort
8.2
Boarding
8.3
Food
6.7
Overall
8.1
Entertainment
6.7
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Crew
8.8
Comfort
8.2
Boarding
8.3
Food
6.7
Overall
8.1
Entertainment
6.7
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Crew
8.8
Comfort
8.2
Boarding
8.3
Food
6.7
Overall
8.1
Entertainment
6.7
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Related info for your journey
Find useful and relevant information for your journey from South Carolina to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near South Carolina?
Book flights to South Carolina if you plan to visit one of these locationsEl Cajon
Chula Vista
Lemon Grove
National City
Imperial Beach
La Mesa
Alpine
Poway
Santee
Coronado
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for South Carolina to San Diego
See prices for flight routes from nearby airports that may be better suited for you.
Top 6 airlines flying from South Carolina to San Diego
Discover the top 6 airlines that operate flights from South Carolina to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$133 | Average$290 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$163 | Average$331 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$258 | Average$483 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$266 | Average$456 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$296 | Average$442 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$350 | Average$464 | FlexibilityNo cancel fee | On-time63% |