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$355+ Cheap flights from Panama City (PTY) to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/4. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SAN
abr. 21 — abr. 281
lun. 4/21
lun. 4/28
1 adult, Economy
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Cheap flight deals from Panama City to San Diego

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated abril 16, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$407
(Copa Airlines)

One-way from

$355
(United Airlines)

Popular in

January

Cheapest in

March

Average price

$713

Good round-trip deal

$233 or less
Provider with most accurate pricing for Panama City Tocumen Intl-San Diego flight deals.
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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-San Diego flights.
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From Panama City Tocumen Intl to San Diego
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One-way flight from Panama City Tocumen Intl to San Diego
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Highest demand for flights based on searches. 3% potential increase in price ($22 potential increase over avg. RT price).
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Cheapest flight prices on average. 0% potential price decrease ($6 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Price to beat on a round-trip flight from Panama City Tocumen Intl to San Diego.
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Find flight deals from Panama City to San Diego

Cheapest flights from Panama City to San Diego
Explore the most affordable flight options available from Panama City to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on abril 16, 2025.

This Copa Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 8/101:15 pmPTY - SAN
Nonstop6h 29mCopa Airlines
vie. 8/158:58 pmSAN - PTY
Nonstop6h 22mCopa Airlines
Deal found 4/16$407
This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 8/103:20 pmPTY - SAN
2 stops19h 49mUnited Airlines
vie. 8/156:15 amSAN - PTY
1 stop10h 22mUnited Airlines
Deal found 4/16$426
This Delta deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/22:20 pmPTY - SAN
1 stop11h 07mDelta
lun. 5/510:30 pmSAN - PTY
1 stop12h 25mDelta
Deal found 4/15$627
This Mytrip deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/23:40 pmPTY - SAN
3 stops35h 02mMultiple Airlines
lun. 5/58:29 amSAN - PTY
3 stops28h 16mMultiple Airlines
Deal found 4/15$765

Cheapflights Fare Finder

Customize your flight search to find flights from Panama City to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 16, 2025.
Use the filters below to find and compare flights from Panama City to San Diego that are best for you.

Fly from

Panama City

Fly to

San Diego

Route

Depart

Return

Price

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

dom. 8/10

1:15 pm-5:44 pm

Nonstop6h 29m

San Diego

vie. 8/15

8:58 pm-5:20 am

Nonstop6h 22m

$407

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

dom. 8/10

7:55 am-11:44 pm

2 stops17h 49m

San Diego

vie. 8/15

7:27 pm-2:14 pm

2 stops16h 47m

$426

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

vie. 5/2

3:40 pm-12:42 am

3 stops35h 02m

San Diego

lun. 5/5

8:29 am-2:45 pm

3 stops28h 16m

$765

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

dom. 5/4

3:20 pm-11:03 am

1 stop21h 43m

$355

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

dom. 5/4

10:05 pm-12:23 pm

3 stops40h 18m

$359

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

mié. 6/25

2:23 pm-8:00 pm

1 stop31h 37m

$379

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

mié. 6/25

1:15 pm-5:54 pm

Nonstop6h 39m

$578

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/16

Compare providers for flights from Panama City to San Diego

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to San Diego in April.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*2 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Panama City-San Diego flights, users find the pricing of AranGrant to be most consistent on Cheapflights vs. AranGrant Users can find the same prices on Panama City-San Diego flight deals on Cheapflights vs. AranGrant >95% of the time. Price accuracy is based on data collected from Panama City-San Diego flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City-San Diego flights, Cheapflights users trust AranGrant the most. AranGrant has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to San Diego

What is the cheapest month to book a flight from Panama City to San Diego?

Currently, August is the cheapest month in which you can book a flight from Panama City to San Diego (average of $286). Flying from Panama City to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to SAN?

Find hourly flight availability from Panama City to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated abril 16, 2025.

It’s optimal to fly from Panama City to San Diego at noon. By choosing this option you can save up to 36% on the cost of your flight, compared to a flight in the afternoon.

Rainfall in San Diego by month

Plan your trip to San Diego by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in San Diego ranges from 0.0 - 2.3 inches per month. February is typically the wettest month, when rainfall can reach 2.3 in. July is typically the driest time to visit San Diego when rainfall is around 0.0 in.

Temperature in San Diego by month

Plan your trip to San Diego by taking into account the average temperature totals by month.

If weather is an important factor for your trip to San Diego, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 57.2 F).

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated abril 16, 2025.
Delta
8.0
Very good
7,916 reviews

Comfort

7.9

Overall

8.0

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,916 reviews
Delta
8.0
Very good
7,916 reviews

Comfort

7.9

Overall

8.0

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Copa Airlines
7.6
Good
1,408 reviews
Delta
8.0
Very good
7,916 reviews

Comfort

7.9

Overall

8.0

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,665 reviews
Delta
8.0
Very good
7,916 reviews

Comfort

7.9

Overall

8.0

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,916 reviews

Comfort

7.9

Overall

8.0

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Avianca
6.7
Okay
2,313 reviews
Delta
8.0
Very good
7,916 reviews

Comfort

7.9

Overall

8.0

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Panama City to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Panama City to San Diego round-trip?

    Copa Airlines, at $407, was found to be the cheapest airline from Panama City to San Diego.Alternate airlines to your destination round-trip include United Airlines and American Airlines. Users have found that Copa Airlines is 40% cheaper than the other options available to this destination.

  • What are the cheapest airlines to fly from Panama City to San Diego one-way?

    $355 is the cheapest one-way deal found within the past few days, from United Airlines. You may also be able to find cheap deals on Delta and Copa Airlines, with prices starting from $379 and $578, respectively.

  • What are the cheapest flights from Panama City to San Diego?

    On average you can expect to pay $235 for a flight from Panama City to San Diego. The cheapest flight overall is $224 while the most popular route, (Panama City Tocumen Intl - San Diego) is currently priced at $398.

  • Can I find deals for flights from Panama City to San Diego that include hotel bookings?

    Yes. In addition to deals on Panama City to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to San Diego.

  • Can I find deals for business class flights from Panama City to San Diego?

    Yes. Cheapflights offers flight deals from Panama City to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to San Diego?

    Currently, August is the cheapest month in which you can book a flight from Panama City to San Diego (average of $286). Flying from Panama City to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
El Cajon
Chula Vista
Lemon Grove
National City
Imperial Beach
La Mesa
Alpine
Poway
Santee
Coronado

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Top airline flying from Panama City to San Diego

Discover the top airline that operate flights from Panama City to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$506Average$680FlexibilityNo cancel feeOn-time69%

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