HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
San Diego

$340+ Cheap flights from Panama City (PTY) to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/6. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SAN
Feb 25 — Mar 41
Tue 2/25
Tue 3/4
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Panama City to San Diego with Cheapflights

1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”
2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.
3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Panama City to San Diego

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$631
(Delta)

One-way from

$340
(Kiwi.com)

Popular in

February

Cheapest in

August

Average price

$775
Provider with most accurate pricing for Panama City Tocumen Intl-San Diego flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City Tocumen Intl-San Diego flights.
Search Deals
From Panama City Tocumen Intl to San Diego
Search Deals
One-way flight from Panama City Tocumen Intl to San Diego
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($40 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 0% potential price decrease ($7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2025
Search Deals

Find flight deals from Panama City to San Diego

Cheapest flights from Panama City to San Diego
Explore the most affordable flight options available from Panama City to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/292:02 pmPTY - SAN
1 stop11h 01mDelta
Mon 6/29:40 pmSAN - PTY
1 stop13h 11mDelta
Deal found 2/19$631
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/131:20 pmPTY - SAN
1 stop11h 13mAmerican Airlines
Sun 5/1810:15 pmSAN - PTY
1 stop12h 00mAmerican Airlines
Deal found 2/19$640
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/133:20 pmPTY - SAN
2 stops20h 04mUnited Airlines
Sun 5/187:25 pmSAN - PTY
2 stops21h 12mUnited Airlines
Deal found 2/20$642
This Expedia deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/283:20 amPTY - SAN
2 stops19h 08mMultiple Airlines
Mon 6/29:52 pmSAN - PTY
2 stops21h 18mMultiple Airlines
Deal found 2/19$871

Find flights from Panama City to San Diego within your budget

Customize your flight search to find flights from Panama City to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.

Fly from

Panama City

Fly to

San Diego

Route

Depart

Return

Price

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Thu 5/29

2:02 pm-11:03 pm

1 stop11h 01m

San Diego

Mon 6/2

9:40 pm-12:51 pm

1 stop13h 11m

$631

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Tue 5/13

1:20 pm-10:33 pm

1 stop11h 13m

San Diego

Sun 5/18

10:15 pm-12:15 pm

1 stop12h 00m

$640

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Tue 5/13

3:20 pm-9:24 am

2 stops20h 04m

San Diego

Sun 5/18

7:25 pm-6:37 pm

2 stops21h 12m

$642

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Wed 5/28

3:20 am-8:28 pm

2 stops19h 08m

San Diego

Mon 6/2

9:52 pm-9:10 pm

2 stops21h 18m

$871

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Thu 3/6

9:55 pm-9:29 am

3 stops38h 34m

$340

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Thu 5/29

2:02 pm-11:03 pm

1 stop11h 01m

$370

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Tue 4/1

1:05 pm-11:08 pm

1 stop12h 03m

$374

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Tue 4/1

3:20 pm-9:24 am

2 stops20h 04m

$375

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/20

Compare providers for flights from Panama City to San Diego

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to San Diego in February.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Panama City-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-San Diego flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama City to San Diego

Get recent, data-driven insights about flights from Panama City to San Diego including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Panama City to San Diego?

Currently, August is the cheapest month in which you can book a flight from Panama City to San Diego (average of $286). Flying from Panama City to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to SAN?

Find hourly flight availability from Panama City to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 20, 2025.

It’s optimal to fly from Panama City to San Diego in the afternoon. By choosing this option you can save up to 36% on the cost of your flight, compared to a flight in the evening.

Rainfall in San Diego by month

Plan your trip to San Diego by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in San Diego ranges from 0.0 - 2.3 inches per month. February is typically the wettest month, when rainfall can reach 2.3 in. July is typically the driest time to visit San Diego when rainfall is around 0.0 in.

Temperature in San Diego by month

Plan your trip to San Diego by taking into account the average temperature totals by month.

If weather is an important factor for your trip to San Diego, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 57.2 F).

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated February 20, 2025.
Delta
8.0
Very good
8,219 reviews

Food

7.3

Boarding

8.2

Comfort

8.0

Overall

8.0

Crew

8.5

Entertainment

7.9

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta
8.0
Very good
8,219 reviews
Delta
8.0
Very good
8,219 reviews

Food

7.3

Boarding

8.2

Comfort

8.0

Overall

8.0

Crew

8.5

Entertainment

7.9

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

United Airlines
7.4
Good
8,765 reviews
Delta
8.0
Very good
8,219 reviews

Food

7.3

Boarding

8.2

Comfort

8.0

Overall

8.0

Crew

8.5

Entertainment

7.9

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,219 reviews

Food

7.3

Boarding

8.2

Comfort

8.0

Overall

8.0

Crew

8.5

Entertainment

7.9

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Panama City to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Panama City to San Diego round-trip?

    Delta, at $631, was found to be the cheapest airline from Panama City to San Diego.Alternate airlines to your destination round-trip include American Airlines and United Airlines. Users have found that Delta is 10% cheaper than the other options available to this destination.

  • What are the cheapest airlines to fly from Panama City to San Diego one-way?

    $370 is the cheapest one-way deal found within the past few days, from Delta. You may also be able to find cheap deals on American Airlines and United Airlines, with prices starting from $374 and $375, respectively.

  • Can I find deals for flights from Panama City to San Diego that include hotel bookings?

    Yes. In addition to deals on Panama City to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to San Diego.

  • Can I find deals for business class flights from Panama City to San Diego?

    Yes. Cheapflights offers flight deals from Panama City to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to San Diego?

    Currently, August is the cheapest month in which you can book a flight from Panama City to San Diego (average of $286). Flying from Panama City to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
El Cajon
Chula Vista
Lemon Grove
National City
Imperial Beach
La Mesa
Alpine
Poway
Santee
Coronado
Borrego Springs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top airline flying from Panama City to San Diego

Discover the top airline that operate flights from Panama City to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$506Average$694FlexibilityNo cancel feeOn-time69%
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.