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$309+ Cheap flights from Panama to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/15. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SAN
Apr 5 — Apr 121
Sat 4/5
Sat 4/12
1 adult, Economy
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Cheap flight deals from Panama to San Diego

Keep the following information in mind while searching for Panama to San Diego flight deals. Data was last updated March 31, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$423
(United Airlines)

One-way from

$309
(Kiwi.com)

Popular in

January

Cheapest in

August

Average price

$729
Provider with most accurate pricing for Panama City Tocumen Intl-San Diego flight deals.
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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-San Diego flights.
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From Panama to San Diego
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One-way flight from Panama to San Diego
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Highest demand for flights based on searches. 2% potential increase in price ($16 potential increase over avg. RT price).
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Cheapest flight prices on average. 0% potential price decrease ($6 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Find flight deals from Panama to San Diego

Cheapest flights from Panama to San Diego
Explore the most affordable flight options available from Panama to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 31, 2025.

This United Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/107:55 amPTY - SAN
2 stops17h 49mUnited Airlines
Fri 8/156:15 amSAN - PTY
1 stop29h 59mUnited Airlines
Deal found 3/31$423
This Copa Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/101:15 pmPTY - SAN
Nonstop6h 29mCopa Airlines
Fri 8/158:58 pmSAN - PTY
Nonstop6h 22mCopa Airlines
Deal found 3/30$427
This Delta deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/37:30 amPTY - SAN
1 stop16h 39mDelta
Mon 5/1210:30 pmSAN - PTY
1 stop12h 18mDelta
Deal found 3/31$610
This Mytrip deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/43:20 amPTY - SAN
3 stops30h 14mMultiple Airlines
Mon 5/125:43 pmSAN - PTY
3 stops38h 27mMultiple Airlines
Deal found 3/31$643
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/11:50 pmPTY - SAN
2 stops24h 18mAmerican Airlines
Sat 11/1511:00 pmSAN - PTY
2 stops13h 20mAmerican Airlines
Deal found 3/30$651
This Orbitz deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/18:05 pmPTY - SAN
3 stops24h 44mAvianca
Sat 11/158:50 pmSAN - PTY
3 stops34h 35mAvianca
Deal found 3/30$1,269

Cheapflights Fare Finder

Customize your flight search to find flights from Panama to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2025.
Use the filters below to find and compare flights from Panama to San Diego that are best for you.

Fly from

Panama

Fly to

San Diego

Route

Depart

Return

Price

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Sun 8/10

7:55 am-11:44 pm

2 stops17h 49m

San Diego

Fri 8/15

6:15 am-2:14 pm

1 stop29h 59m

$423

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Sun 8/10

1:15 pm-5:44 pm

Nonstop6h 29m

San Diego

Fri 8/15

8:58 pm-5:20 am

Nonstop6h 22m

$427

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Tue 5/6

2:20 pm-12:33 pm

1 stop24h 13m

San Diego

Sun 5/11

10:30 pm-12:48 pm

1 stop12h 18m

$617

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Sun 5/4

3:20 am-7:34 am

3 stops30h 14m

San Diego

Mon 5/12

5:43 pm-10:10 am

3 stops38h 27m

$643

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Tue 5/13

8:10 pm-11:59 pm

2 stops29h 49m

San Diego

Sun 5/18

6:15 am-10:25 am

3 stops26h 10m

$1,401

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Thu 5/15

3:20 am-6:03 pm

3 stops40h 43m

$309

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Wed 5/21

10:00 am-12:23 am

2 stops16h 23m

$343

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Fri 5/16

2:13 pm-11:42 pm

1 stop11h 29m

$362

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Wed 6/25

1:15 pm-5:54 pm

Nonstop6h 39m

$715

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Sat 7/19

8:10 pm-11:44 pm

3 stops29h 34m

$866

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/31

Best time to book a flight from Panama to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to San Diego

What is the cheapest month to book a flight from Panama to San Diego?

Currently, August is the cheapest month in which you can book a flight from Panama to San Diego (average of $286). Flying from Panama to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PA to SAN?

Find hourly flight availability from Panama to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 31, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama to San Diego as you normally would.

Rainfall in San Diego by month

Plan your trip to San Diego by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in San Diego ranges from 0.0 - 2.3 inches per month. February is typically the wettest month, when rainfall can reach 2.3 in. July is typically the driest time to visit San Diego when rainfall is around 0.0 in.

Temperature in San Diego by month

Plan your trip to San Diego by taking into account the average temperature totals by month.

If weather is an important factor for your trip to San Diego, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 57.2 F).

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated March 31, 2025.
Delta
8.0
Very good
7,899 reviews

Food

7.3

Overall

8.0

Entertainment

7.9

Comfort

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,899 reviews
Delta
8.0
Very good
7,899 reviews

Food

7.3

Overall

8.0

Entertainment

7.9

Comfort

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Copa Airlines
7.6
Good
1,400 reviews
Delta
8.0
Very good
7,899 reviews

Food

7.3

Overall

8.0

Entertainment

7.9

Comfort

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,614 reviews
Delta
8.0
Very good
7,899 reviews

Food

7.3

Overall

8.0

Entertainment

7.9

Comfort

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Avianca
6.7
Okay
2,301 reviews
Delta
8.0
Very good
7,899 reviews

Food

7.3

Overall

8.0

Entertainment

7.9

Comfort

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Panama to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Diego from Panama?

    Most people fly into San Diego (SAN) if they book a flight to San Diego from Panama. San Diego is conveniently located just 2.6 mi from San Diego’s city center.

  • What are the cheapest airlines to fly from Panama to San Diego one-way?

    One-way options have recently been found by users for as low as $343 on United Airlines. Other airlines that offer cheap prices include Delta from $362 and Copa Airlines from $715 one-way.

  • Can I find deals for flights from Panama to San Diego that include hotel bookings?

    Yes. In addition to deals on Panama to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to San Diego.

  • Can I find deals for business class flights from Panama to San Diego?

    Yes. Cheapflights offers flight deals from Panama to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to San Diego?

    Currently, August is the cheapest month in which you can book a flight from Panama to San Diego (average of $286). Flying from Panama to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama?

Book flights to Panama if you plan to visit one of these locations
El Cajon
Chula Vista
Lemon Grove
National City
Imperial Beach
La Mesa
Alpine
Poway
Santee
Coronado
Borrego Springs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Panama to San Diego

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Panama to San Diego

Discover the top airline that operate flights from Panama to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$506Average$689FlexibilityNo cancel feeOn-time69%
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