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$281+ Cheap flights from Panama to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/10. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SAN
Apr 30 — May 71
Wed 4/30
Wed 5/7
1 adult, Economy
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Cheap flight deals from Panama to San Diego

Keep the following information in mind while searching for Panama to San Diego flight deals. Data was last updated April 25, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$406
(Copa Airlines)

One-way from

$281
(United Airlines)

Popular in

January

Cheapest in

March

Average price

$713

Good round-trip deal

$224 or less
Provider with most accurate pricing for Panama City Tocumen Intl-San Diego flight deals.
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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-San Diego flights.
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From Panama to San Diego
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One-way flight from Panama to San Diego
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Highest demand for flights based on searches. 3% potential increase in price ($22 potential increase over avg. RT price).
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Cheapest flight prices on average. 0% potential price decrease ($6 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Price to beat on a round-trip flight from Panama to San Diego.
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Find flight deals from Panama to San Diego

Cheapest flights from Panama to San Diego
Explore the most affordable flight options available from Panama to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 25, 2025.

This Copa Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/101:15 pmPTY - SAN
Nonstop6h 29mCopa Airlines
Fri 8/158:58 pmSAN - PTY
Nonstop6h 22mCopa Airlines
Deal found 4/25$406
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/43:15 pmPTY - SAN
1 stop23h 33mUnited Airlines
Mon 8/256:15 amSAN - PTY
1 stop11h 55mUnited Airlines
Deal found 4/23$412
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/103:16 pmPTY - SAN
2 stops21h 24mAmerican Airlines
Fri 8/1511:00 pmSAN - PTY
1 stop13h 15mAmerican Airlines
Deal found 4/24$425
This Mytrip deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/3110:05 pmPTY - SAN
3 stops35h 08mMultiple Airlines
Sun 6/86:15 amSAN - PTY
2 stops26h 20mMultiple Airlines
Deal found 4/25$736
This Avianca deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/163:40 pmPTY - SAN
2 stops19h 55mAvianca
Fri 6/2011:15 amSAN - PTY
2 stops21h 10mAvianca
Deal found 4/25$1,336

Cheapflights Fare Finder

Customize your flight search to find flights from Panama to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 25, 2025.
Use the filters below to find and compare flights from Panama to San Diego that are best for you.

Fly from

Panama

Fly to

San Diego

Route

Depart

Return

Price

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Sun 8/10

1:15 pm-5:44 pm

Nonstop6h 29m

San Diego

Fri 8/15

8:58 pm-5:20 am

Nonstop6h 22m

$406

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Mon 8/4

3:15 pm-12:48 pm

1 stop23h 33m

San Diego

Mon 8/25

6:15 am-8:10 pm

1 stop11h 55m

$412

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Sun 8/10

3:16 pm-10:40 am

2 stops21h 24m

San Diego

Fri 8/15

7:56 pm-2:15 pm

2 stops16h 19m

$425

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Sat 5/31

10:05 pm-7:13 am

3 stops35h 08m

San Diego

Sun 6/8

6:15 am-10:35 am

2 stops26h 20m

$736

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Fri 5/16

3:40 pm-9:35 am

2 stops19h 55m

San Diego

Fri 6/20

11:15 am-10:25 am

2 stops21h 10m

$1,336

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Sun 8/10

3:30 pm-12:15 am

2 stops34h 45m

$281

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Fri 5/9

9:21 pm-7:13 am

3 stops35h 52m

$348

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Fri 5/9

2:13 pm-11:42 pm

1 stop11h 29m

$355

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Wed 6/25

1:50 pm-8:50 am

2 stops21h 00m

$381

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Mon 6/30

1:15 pm-5:54 pm

Nonstop6h 39m

$436

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/25

Best time to book a flight from Panama to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to San Diego

What is the cheapest month to book a flight from Panama to San Diego?

Currently, August is the cheapest month in which you can book a flight from Panama to San Diego (average of $286). Flying from Panama to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PA to SAN?

Find hourly flight availability from Panama to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 25, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama to San Diego as you normally would.

Rainfall in San Diego by month

Plan your trip to San Diego by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in San Diego ranges from 0.0 - 2.3 inches per month. February is typically the wettest month, when rainfall can reach 2.3 in. July is typically the driest time to visit San Diego when rainfall is around 0.0 in.

Temperature in San Diego by month

Plan your trip to San Diego by taking into account the average temperature totals by month.

If weather is an important factor for your trip to San Diego, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 57.2 F).

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated April 25, 2025.
Delta
8.0
Very good
7,920 reviews

Boarding

8.2

Food

7.3

Overall

8.0

Entertainment

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,920 reviews
Delta
8.0
Very good
7,920 reviews

Boarding

8.2

Food

7.3

Overall

8.0

Entertainment

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Copa Airlines
7.6
Good
1,411 reviews
Delta
8.0
Very good
7,920 reviews

Boarding

8.2

Food

7.3

Overall

8.0

Entertainment

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,685 reviews
Delta
8.0
Very good
7,920 reviews

Boarding

8.2

Food

7.3

Overall

8.0

Entertainment

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,920 reviews

Boarding

8.2

Food

7.3

Overall

8.0

Entertainment

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Avianca
6.7
Okay
2,317 reviews
Delta
8.0
Very good
7,920 reviews

Boarding

8.2

Food

7.3

Overall

8.0

Entertainment

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Panama to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Diego from Panama?

    Most people fly into San Diego (SAN) if they book a flight to San Diego from Panama. San Diego is conveniently located just 2.6 mi from San Diego’s city center.

  • What are the cheapest airlines to fly from Panama to San Diego one-way?

    One-way options have recently been found by users for as low as $281 on United Airlines. Other airlines that offer cheap prices include Delta from $355 and American Airlines from $381 one-way.

  • What are the cheapest flights from Panama to San Diego?

    Looking at all options, your cheapest flight can be booked for $224. While the most popular route (Panama City Tocumen Intl - San Diego) can be booked for $397 on average our data indicates $235 when flying from Panama to San Diego.

  • Can I find deals for flights from Panama to San Diego that include hotel bookings?

    Yes. In addition to deals on Panama to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to San Diego.

  • Can I find deals for business class flights from Panama to San Diego?

    Yes. Cheapflights offers flight deals from Panama to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to San Diego?

    Currently, August is the cheapest month in which you can book a flight from Panama to San Diego (average of $286). Flying from Panama to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama?

Book flights to Panama if you plan to visit one of these locations
El Cajon
Chula Vista
Lemon Grove
National City
Imperial Beach
La Mesa
Alpine
Poway
Santee
Coronado

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Panama to San Diego

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Panama to San Diego

Discover the top airline that operate flights from Panama to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 25, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$506Average$680FlexibilityNo cancel feeOn-time69%

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