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$340+ Cheap flights from Panama to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/6. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SAN
Feb 25 — Mar 41
Tue 2/25
Tue 3/4
1 adult, Economy
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Cheap flight deals from Panama to San Diego

Keep the following information in mind while searching for Panama to San Diego flight deals. Data was last updated February 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$631
(Delta)

One-way from

$340
(Kiwi.com)

Popular in

February

Cheapest in

August

Average price

$775
Provider with most accurate pricing for Panama City Tocumen Intl-San Diego flight deals.
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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-San Diego flights.
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From Panama to San Diego
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One-way flight from Panama to San Diego
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Highest demand for flights based on searches. 5% potential increase in price ($40 potential increase over avg. RT price).
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Cheapest flight prices on average. 0% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in February 2025
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Find flight deals from Panama to San Diego

Cheapest flights from Panama to San Diego
Explore the most affordable flight options available from Panama to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/292:02 pmPTY - SAN
1 stop11h 01mDelta
Mon 6/29:40 pmSAN - PTY
1 stop13h 11mDelta
Deal found 2/19$631
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/131:20 pmPTY - SAN
1 stop11h 13mAmerican Airlines
Sun 5/1810:15 pmSAN - PTY
1 stop12h 00mAmerican Airlines
Deal found 2/19$640
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/133:20 pmPTY - SAN
2 stops20h 04mUnited Airlines
Sun 5/187:25 pmSAN - PTY
2 stops21h 12mUnited Airlines
Deal found 2/20$642
This Expedia deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/283:20 amPTY - SAN
2 stops19h 08mMultiple Airlines
Mon 6/29:52 pmSAN - PTY
2 stops21h 18mMultiple Airlines
Deal found 2/19$871

Find flights from Panama to San Diego within your budget

Customize your flight search to find flights from Panama to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.

Fly from

Panama

Fly to

San Diego

Route

Depart

Return

Price

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Thu 5/29

2:02 pm-11:03 pm

1 stop11h 01m

San Diego

Mon 6/2

9:40 pm-12:51 pm

1 stop13h 11m

$631

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Tue 5/13

1:20 pm-10:33 pm

1 stop11h 13m

San Diego

Sun 5/18

10:15 pm-12:15 pm

1 stop12h 00m

$640

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Tue 5/13

3:20 pm-9:24 am

2 stops20h 04m

San Diego

Sun 5/18

7:25 pm-6:37 pm

2 stops21h 12m

$642

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Wed 5/28

3:20 am-8:28 pm

2 stops19h 08m

San Diego

Mon 6/2

9:52 pm-9:10 pm

2 stops21h 18m

$871

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Thu 3/6

9:55 pm-9:29 am

3 stops38h 34m

$340

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Thu 5/29

2:02 pm-11:03 pm

1 stop11h 01m

$370

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Tue 4/1

1:05 pm-11:08 pm

1 stop12h 03m

$374

Panama CitySan Diego

PTY - SAN

PTYSAN

Panama City Tocumen Intl

Tue 4/1

3:20 pm-9:24 am

2 stops20h 04m

$375

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/20

Best time to book a flight from Panama to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama to San Diego

Get recent, data-driven insights about flights from Panama to San Diego including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Panama to San Diego?

Currently, August is the cheapest month in which you can book a flight from Panama to San Diego (average of $286). Flying from Panama to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PA to SAN?

Find hourly flight availability from Panama to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 20, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama to San Diego as you normally would.

Rainfall in San Diego by month

Plan your trip to San Diego by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in San Diego ranges from 0.0 - 2.3 inches per month. February is typically the wettest month, when rainfall can reach 2.3 in. July is typically the driest time to visit San Diego when rainfall is around 0.0 in.

Temperature in San Diego by month

Plan your trip to San Diego by taking into account the average temperature totals by month.

If weather is an important factor for your trip to San Diego, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 57.2 F).

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated February 20, 2025.
Delta
8.0
Very good
8,220 reviews

Food

7.3

Overall

8.0

Comfort

8.0

Crew

8.5

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta
8.0
Very good
8,220 reviews
Delta
8.0
Very good
8,220 reviews

Food

7.3

Overall

8.0

Comfort

8.0

Crew

8.5

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

United Airlines
7.4
Good
8,766 reviews
Delta
8.0
Very good
8,220 reviews

Food

7.3

Overall

8.0

Comfort

8.0

Crew

8.5

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,220 reviews

Food

7.3

Overall

8.0

Comfort

8.0

Crew

8.5

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Panama to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Diego from Panama?

    Most people fly into San Diego (SAN) if they book a flight to San Diego from Panama. San Diego is conveniently located just 2.6 mi from San Diego’s city center.

  • What are the cheapest airlines to fly from Panama to San Diego one-way?

    One-way options have recently been found by users for as low as $370 on Delta. Other airlines that offer cheap prices include American Airlines from $374 and United Airlines from $375 one-way.

  • Can I find deals for flights from Panama to San Diego that include hotel bookings?

    Yes. In addition to deals on Panama to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to San Diego.

  • Can I find deals for business class flights from Panama to San Diego?

    Yes. Cheapflights offers flight deals from Panama to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to San Diego?

    Currently, August is the cheapest month in which you can book a flight from Panama to San Diego (average of $286). Flying from Panama to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama?

Book flights to Panama if you plan to visit one of these locations
El Cajon
Chula Vista
Lemon Grove
National City
Imperial Beach
La Mesa
Alpine
Poway
Santee
Coronado
Borrego Springs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Panama to San Diego

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Panama to San Diego

Discover the top airline that operate flights from Panama to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$506Average$694FlexibilityNo cancel feeOn-time69%
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