HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
San Diego

$119+ Cheap flights from Myrtle Beach to San Diego (MYR - SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/28. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — SAN
Apr 2 — Apr 91
Wed 4/2
Wed 4/9
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Myrtle Beach to San Diego with Cheapflights

1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”
2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.
3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Myrtle Beach Intl to San Diego are usually found in September or August, booked 70 days in advance, depart on a Tuesday or Friday and return on a Tuesday

Cheap flight deals from Myrtle Beach to San Diego

Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 28, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$339
(Mytrip)

One-way from

$119
(Mytrip)

Popular in

May

Cheapest in

September

Average price

$532
Provider with most accurate pricing for Myrtle Beach Intl-San Diego flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-San Diego flights.
Search Deals
From Myrtle Beach Intl to San Diego
Search Deals
One-way flight from Myrtle Beach Intl to San Diego
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($52 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2025
Search Deals

Find flight deals from Myrtle Beach to San Diego

Cheapest flights from Myrtle Beach to San Diego
Explore the most affordable flight options available from Myrtle Beach to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 28, 2025.

This Mytrip deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/16:15 amMYR - SAN
3 stops28h 19mSpirit Airlines
Mon 5/58:29 amSAN - MYR
3 stops25h 35mSpirit Airlines
Deal found 3/25$339
This American Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/164:42 pmMYR - SAN
1 stop10h 14mAmerican Airlines
Wed 4/2310:45 pmSAN - MYR
1 stop6h 29mAmerican Airlines
Deal found 3/26$351
This United Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/111:08 amMYR - SAN
2 stops16h 15mUnited Airlines
Mon 5/59:25 pmSAN - MYR
1 stop10h 02mUnited Airlines
Deal found 3/25$381
This Mytrip deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2412:08 pmMYR - SAN
2 stops25h 17mMultiple Airlines
Sun 4/276:15 amSAN - MYR
2 stops26h 11mMultiple Airlines
Deal found 3/26$389
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/2411:10 amMYR - SAN
1 stop9h 56mDelta
Mon 6/306:15 amSAN - MYR
1 stop7h 02mDelta
Deal found 3/26$392
This Southwest deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/67:10 pmMYR - SAN
1 stop6h 30mSouthwest
Tue 6/108:50 amSAN - MYR
2 stops10h 20mSouthwest
Deal found 3/26$394
This Alaska Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/242:27 pmMYR - SAN
2 stops20h 15mAlaska Airlines
Mon 6/302:15 pmSAN - MYR
3 stops19h 17mAlaska Airlines
Deal found 3/26$768

Cheapflights Fare Finder

Customize your flight search to find flights from Myrtle Beach to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
Use the filters below to find and compare flights from Myrtle Beach to San Diego that are best for you.

Fly from

Myrtle Beach

Fly to

San Diego

Route

Depart

Return

Price

Myrtle BeachSan Diego

MYR - SAN

MYRSAN

Myrtle Beach Intl

Thu 5/1

6:15 am-7:34 am

3 stops28h 19m

San Diego

Mon 5/5

8:29 am-1:04 pm

3 stops25h 35m

$339

Myrtle BeachSan Diego

MYR - SAN

MYRSAN

Myrtle Beach Intl

Wed 4/16

4:42 pm-11:56 pm

1 stop10h 14m

San Diego

Wed 4/23

10:45 pm-8:14 am

1 stop6h 29m

$351

Myrtle BeachSan Diego

MYR - SAN

MYRSAN

Myrtle Beach Intl

Thu 5/1

11:08 am-12:23 am

2 stops16h 15m

San Diego

Mon 5/5

9:25 pm-10:27 am

1 stop10h 02m

$381

Myrtle BeachSan Diego

MYR - SAN

MYRSAN

Myrtle Beach Intl

Thu 4/24

12:08 pm-10:25 am

2 stops25h 17m

San Diego

Sun 4/27

6:15 am-11:26 am

2 stops26h 11m

$389

Myrtle BeachSan Diego

MYR - SAN

MYRSAN

Myrtle Beach Intl

Tue 6/24

11:10 am-6:06 pm

1 stop9h 56m

San Diego

Mon 6/30

6:15 am-4:17 pm

1 stop7h 02m

$392

Myrtle BeachSan Diego

MYR - SAN

MYRSAN

Myrtle Beach Intl

Fri 6/6

7:10 pm-10:40 pm

1 stop6h 30m

San Diego

Tue 6/10

8:50 am-10:10 pm

2 stops10h 20m

$394

Myrtle BeachSan Diego

MYR - SAN

MYRSAN

Myrtle Beach Intl

Tue 6/24

2:27 pm-7:42 am

2 stops20h 15m

San Diego

Mon 6/30

2:15 pm-12:32 pm

3 stops19h 17m

$768

Myrtle BeachSan Diego

MYR - SAN

MYRSAN

Myrtle Beach Intl

Mon 4/28

6:15 am-12:42 am

3 stops45h 27m

$119

Myrtle BeachSan Diego

MYR - SAN

MYRSAN

Myrtle Beach Intl

Tue 4/22

11:29 am-6:05 pm

1 stop9h 36m

$176

Myrtle BeachSan Diego

MYR - SAN

MYRSAN

Myrtle Beach Intl

Sun 5/25

5:00 am-10:59 am

1 stop8h 59m

$179

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/27

Showing 1-10 of 14 results
1
2

Compare providers for flights from Myrtle Beach to San Diego

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to San Diego in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Myrtle Beach-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Myrtle Beach-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Myrtle Beach-San Diego flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Myrtle Beach-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Myrtle Beach to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to San Diego

How far ahead should I book a flight from Myrtle Beach to San Diego?

Use this chart to determine the optimal time to book a round-trip flight from Myrtle Beach to San Diego. Price data was last updated on March 21, 2025.

The best time to book flights from Myrtle Beach to San Diego is 70 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Myrtle Beach to San Diego?

Currently, August is the cheapest month in which you can book a flight from Myrtle Beach to San Diego (average of $286). Flying from Myrtle Beach to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to SAN?

Find hourly flight availability from Myrtle Beach to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 28, 2025.

When flying from Myrtle Beach to San Diego, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 13% versus a flight in the afternoon.

Rainfall in San Diego by month

Plan your trip to San Diego by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in San Diego ranges from 0.0 - 2.3 inches per month. February is typically the wettest month, when rainfall can reach 2.3 in. July is typically the driest time to visit San Diego when rainfall is around 0.0 in.

Temperature in San Diego by month

Plan your trip to San Diego by taking into account the average temperature totals by month.

If weather is an important factor for your trip to San Diego, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 57.2 F).

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated March 28, 2025.
Southwest
8.1
Very good
4,274 reviews

Comfort

8.1

Crew

8.7

Food

7.1

Boarding

8.2

Entertainment

7.6

Overall

8.1

Reviews

1 / 20
10.0
Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.
Southwest
8.1
Very good
4,274 reviews
Southwest
8.1
Very good
4,274 reviews

Comfort

8.1

Crew

8.7

Food

7.1

Boarding

8.2

Entertainment

7.6

Overall

8.1

Reviews

1 / 20
10.0
Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.
Alaska Airlines
8.0
Very good
9,798 reviews
Southwest
8.1
Very good
4,274 reviews

Comfort

8.1

Crew

8.7

Food

7.1

Boarding

8.2

Entertainment

7.6

Overall

8.1

Reviews

1 / 20
10.0
Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.
Delta
8.0
Very good
7,897 reviews
Southwest
8.1
Very good
4,274 reviews

Comfort

8.1

Crew

8.7

Food

7.1

Boarding

8.2

Entertainment

7.6

Overall

8.1

Reviews

1 / 20
10.0
Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.
United Airlines
7.4
Good
8,603 reviews
Southwest
8.1
Very good
4,274 reviews

Comfort

8.1

Crew

8.7

Food

7.1

Boarding

8.2

Entertainment

7.6

Overall

8.1

Reviews

1 / 20
10.0
Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,274 reviews

Comfort

8.1

Crew

8.7

Food

7.1

Boarding

8.2

Entertainment

7.6

Overall

8.1

Reviews

1 / 20
10.0
Excellent

Merlyn,Feb 2025

LAX - SMF

New Terminal is neat, lost of stores and places to catch a bite.

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Myrtle Beach to San Diego round-trip?

    Cheapflights users have booked flights from Myrtle Beach to San Diego round-trip from $339. Other airlines that can offer you cheap pricing are American Airlines, from $351, and United Airlines, from $381. Spirit Airlines is currently priced 28% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Myrtle Beach to San Diego one-way?

    To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $119. Delta flights start at $176 while deals on American Airlines start at $179 one-way.

  • Can I find deals for flights from Myrtle Beach to San Diego that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to San Diego.

  • Can I find deals for business class flights from Myrtle Beach to San Diego?

    Yes. Cheapflights offers flight deals from Myrtle Beach to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to San Diego?

    Currently, August is the cheapest month in which you can book a flight from Myrtle Beach to San Diego (average of $286). Flying from Myrtle Beach to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Myrtle Beach?

Book flights to Myrtle Beach if you plan to visit one of these locations
El Cajon
Chula Vista
Lemon Grove
National City
Imperial Beach
La Mesa
Alpine
Poway
Santee
Coronado
Borrego Springs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Myrtle Beach to San Diego

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to Las Vegas flights
Charlotte to Los Angeles flights
Charlotte to San Francisco flights
Charleston to Las Vegas flights
Charlotte to Ontario flights
Charlotte to San Diego flights
Columbia to Las Vegas flights
Greenville to Las Vegas flights
Savannah to Las Vegas flights
Charlotte to Santa Ana flights
Charlotte to Burbank flights
Charleston to San Diego flights
Charlotte to Sacramento flights
Charleston to San Francisco flights
Charleston to Los Angeles flights
Myrtle Beach to Las Vegas flights
Greenville to Sacramento flights
Greenville to San Francisco flights
Greenville to Los Angeles flights
Columbia to Los Angeles flights
Savannah to Los Angeles flights
Charlotte to Oakland flights
Greenville to Ontario flights
Augusta to Las Vegas flights
Savannah to San Francisco flights
Savannah to San Diego flights
Charlotte to San Jose flights
Columbia to San Diego flights
Columbia to San Francisco flights
Greenville to San Diego flights
Charleston to Ontario flights
Charlotte to Reno flights
Savannah to Santa Ana flights
Charleston to Reno flights
Greenville to San Jose flights
Charlotte to Fresno flights
Augusta to San Diego flights
Augusta to San Francisco flights
Greenville to Santa Ana flights
Charleston to Santa Ana flights
Columbia to Ontario flights
Columbia to Santa Ana flights
Charlotte to Palm Springs flights
Savannah to Ontario flights
Myrtle Beach to Los Angeles flights
Greenville to Oakland flights
Charlotte to Long Beach flights
Greenville to Fresno flights
Charleston to Oakland flights
Charlotte to San Luis Obispo flights

Top 3 airlines flying from Myrtle Beach to San Diego

Discover the top 3 airlines that operate flights from Myrtle Beach to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$316Average$463FlexibilityNo cancel feeOn-time71%
DeltaCheapest$346Average$442FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$442Average$496FlexibilityNo cancel feeOn-time63%
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.