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$78+ Cheap flights from Mississippi to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/7. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — SAN
Apr 5 — Apr 121
Sat 4/5
Sat 4/12
1 adult, Economy
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Cheap flight deals from Mississippi to San Diego

Keep the following information in mind while searching for Mississippi to San Diego flight deals. Data was last updated March 31, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$135
(Mytrip)

One-way from

$78
(Cheapflightsfares)

Popular in

December

Cheapest in

February

Average price

$567
Provider with most accurate pricing for Jackson-Evers Intl-San Diego flight deals.
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Provider most trusted by Cheapflights users for Jackson-Evers Intl-San Diego flights.
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From Mississippi to San Diego
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One-way flight from Mississippi to San Diego
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Highest demand for flights based on searches. 4% potential increase in price ($23 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Find flight deals from Mississippi to San Diego

Cheapest flights from Mississippi to San Diego
Explore the most affordable flight options available from Mississippi to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 31, 2025.

This Mytrip deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/79:08 pmMEM - SAN
1 stop28h 48mSpirit Airlines
Mon 5/125:43 pmSAN - MEM
1 stop24h 30mSpirit Airlines
Deal found 3/29$135
This Mytrip deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/251:01 pmMEM - SAN
2 stops37h 41mMultiple Airlines
Mon 4/289:08 pmSAN - MEM
1 stop21h 55mMultiple Airlines
Deal found 3/30$187
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/35:45 pmGPT - SAN
1 stop6h 09mAmerican Airlines
Wed 5/71:48 pmSAN - GPT
1 stop8h 10mAmerican Airlines
Deal found 3/31$277
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/245:58 pmMEM - SAN
1 stop7h 44mDelta
Wed 5/2810:30 pmSAN - MEM
1 stop8h 51mDelta
Deal found 3/30$287
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/196:21 pmBTR - SAN
1 stop5h 26mAmerican Airlines
Tue 9/2310:48 amSAN - BTR
1 stop5h 12mAmerican Airlines
Deal found 3/30$289
This United Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/32:09 pmPIB - SAN
1 stop9h 13mUnited Airlines
Wed 5/77:40 pmSAN - PIB
2 stops11h 50mUnited Airlines
Deal found 3/31$290
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/41:40 pmBTR - SAN
1 stop9h 38mDelta
Fri 8/811:00 amSAN - BTR
1 stop8h 58mDelta
Deal found 3/30$297
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/146:02 pmGPT - SAN
1 stop7h 25mDelta
Fri 4/1810:30 pmSAN - GPT
1 stop8h 29mDelta
Deal found 3/30$297
This Frontier deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/37:44 pmMEM - SAN
1 stop6h 30mFrontier
Tue 4/86:25 amSAN - MEM
1 stop10h 29mFrontier
Deal found 3/29$308
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1512:49 pmMOB - SAN
1 stop7h 44mDelta
Sat 4/1910:30 pmSAN - MOB
1 stop8h 05mDelta
Deal found 3/30$313
This United Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/144:55 pmGPT - SAN
1 stop6h 27mUnited Airlines
Fri 4/187:09 amSAN - GPT
2 stops10h 37mUnited Airlines
Deal found 3/30$330
This Southwest deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/76:10 amMEM - SAN
1 stop6h 00mSouthwest
Tue 5/138:40 amSAN - MEM
2 stops12h 00mSouthwest
Deal found 3/31$336

Cheapflights Fare Finder

Customize your flight search to find flights from Mississippi to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2025.
Use the filters below to find and compare flights from Mississippi to San Diego that are best for you.

Fly from

Mississippi

Fly to

San Diego

Route

Depart

Return

Price

MemphisSan Diego

MEM - SAN

MEMSAN

Memphis

Wed 5/7

9:08 pm-11:56 pm

1 stop28h 48m

San Diego

Mon 5/12

5:43 pm-8:13 pm

1 stop24h 30m

$135

MemphisSan Diego

MEM - SAN

MEMSAN

Memphis

Fri 4/25

1:01 pm-12:42 am

2 stops37h 41m

San Diego

Mon 4/28

9:08 pm-9:03 pm

1 stop21h 55m

$187

GulfportSan Diego

GPT - SAN

GPTSAN

Gulfport Biloxi Regional

Sat 5/3

5:45 pm-9:54 pm

1 stop6h 09m

San Diego

Wed 5/7

1:48 pm-11:58 pm

1 stop8h 10m

$277

MemphisSan Diego

MEM - SAN

MEMSAN

Memphis

Sat 5/24

5:58 pm-11:42 pm

1 stop7h 44m

San Diego

Wed 5/28

10:30 pm-9:21 am

1 stop8h 51m

$287

Baton RougeSan Diego

BTR - SAN

BTRSAN

Baton Rouge Ryan

Fri 9/19

6:21 pm-9:47 pm

1 stop5h 26m

San Diego

Tue 9/23

10:48 am-6:00 pm

1 stop5h 12m

$289

LaurelSan Diego

PIB - SAN

PIBSAN

Laurel Hattiesburg-PineBelt

Sat 5/3

2:09 pm-9:22 pm

1 stop9h 13m

San Diego

Wed 5/7

7:40 pm-9:30 am

2 stops11h 50m

$290

Baton RougeSan Diego

BTR - SAN

BTRSAN

Baton Rouge Ryan

Mon 8/4

1:40 pm-9:18 pm

1 stop9h 38m

San Diego

Fri 8/8

11:00 am-9:58 pm

1 stop8h 58m

$297

GulfportSan Diego

GPT - SAN

GPTSAN

Gulfport Biloxi Regional

Mon 4/14

6:02 pm-11:27 pm

1 stop7h 25m

San Diego

Fri 4/18

10:30 pm-8:59 am

1 stop8h 29m

$297

MobileSan Diego

MOB - SAN

MOBSAN

Mobile

Tue 4/15

12:49 pm-6:33 pm

1 stop7h 44m

San Diego

Sat 4/19

10:30 pm-8:35 am

1 stop8h 05m

$313

GulfportSan Diego

GPT - SAN

GPTSAN

Gulfport Biloxi Regional

Mon 4/14

4:55 pm-9:22 pm

1 stop6h 27m

San Diego

Fri 4/18

7:09 am-7:46 pm

2 stops10h 37m

$330

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/31

Showing 1-10 of 38 results
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Best time to book a flight from Mississippi to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to San Diego

What is the cheapest month to book a flight from Mississippi to San Diego?

Currently, August is the cheapest month in which you can book a flight from Mississippi to San Diego (average of $286). Flying from Mississippi to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS to SAN?

Find hourly flight availability from Mississippi to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 31, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mississippi to San Diego as you normally would.

Rainfall in San Diego by month

Plan your trip to San Diego by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in San Diego ranges from 0.0 - 2.3 inches per month. February is typically the wettest month, when rainfall can reach 2.3 in. July is typically the driest time to visit San Diego when rainfall is around 0.0 in.

Temperature in San Diego by month

Plan your trip to San Diego by taking into account the average temperature totals by month.

If weather is an important factor for your trip to San Diego, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 57.2 F).

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated March 31, 2025.
To help decide which airline to fly from Mississippi to San Diego, see what other customers have to say about Alaska Airlines, Southwest and Delta. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
9,818 reviews

Food

7.1

Comfort

7.9

Overall

8.0

Crew

8.5

Entertainment

7.1

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Seleste,Dec 2024

FAT - SAN

The attention and efficiency of the staff and the good handling of the pilot
Alaska Airlines
8.0
Very good
9,818 reviews
Alaska Airlines
8.0
Very good
9,818 reviews

Food

7.1

Comfort

7.9

Overall

8.0

Crew

8.5

Entertainment

7.1

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Seleste,Dec 2024

FAT - SAN

The attention and efficiency of the staff and the good handling of the pilot
Southwest
8.0
Very good
4,275 reviews
Alaska Airlines
8.0
Very good
9,818 reviews

Food

7.1

Comfort

7.9

Overall

8.0

Crew

8.5

Entertainment

7.1

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Seleste,Dec 2024

FAT - SAN

The attention and efficiency of the staff and the good handling of the pilot
Delta
8.0
Very good
7,899 reviews
Alaska Airlines
8.0
Very good
9,818 reviews

Food

7.1

Comfort

7.9

Overall

8.0

Crew

8.5

Entertainment

7.1

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Seleste,Dec 2024

FAT - SAN

The attention and efficiency of the staff and the good handling of the pilot
United Airlines
7.4
Good
8,614 reviews
Alaska Airlines
8.0
Very good
9,818 reviews

Food

7.1

Comfort

7.9

Overall

8.0

Crew

8.5

Entertainment

7.1

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Seleste,Dec 2024

FAT - SAN

The attention and efficiency of the staff and the good handling of the pilot
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
9,818 reviews

Food

7.1

Comfort

7.9

Overall

8.0

Crew

8.5

Entertainment

7.1

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Seleste,Dec 2024

FAT - SAN

The attention and efficiency of the staff and the good handling of the pilot

Related info for your journey

Find useful and relevant information for your journey from Mississippi to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Diego from Mississippi?

    For a flight from Mississippi to San Diego, you will be flying into San Diego. San Diego (SAN) is just 2.6 mi from the center of the city.

  • What are the cheapest airlines to fly from Mississippi to San Diego one-way?

    One-way options have recently been found by users for as low as $78 on Spirit Airlines. Other airlines that offer cheap prices include Frontier from $119 and Delta from $139 one-way.

  • What are the most popular routes from Mississippi to San Diego?

    The most popular flight routes from Mississippi to San Diego are Memphis - San Diego, Gulfport Biloxi Regional - San Diego and Baton Rouge Ryan - San Diego.

  • Can I find deals for flights from Mississippi to San Diego that include hotel bookings?

    Yes. In addition to deals on Mississippi to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to San Diego.

  • Can I find deals for business class flights from Mississippi to San Diego?

    Yes. Cheapflights offers flight deals from Mississippi to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to San Diego?

    Currently, August is the cheapest month in which you can book a flight from Mississippi to San Diego (average of $286). Flying from Mississippi to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Mississippi?

Book flights to Mississippi if you plan to visit one of these locations
El Cajon
Chula Vista
Lemon Grove
National City
Imperial Beach
La Mesa
Alpine
Poway
Santee
Coronado
Borrego Springs

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Alternative routes for Mississippi to San Diego

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Mississippi to San Diego

Discover the top 4 airlines that operate flights from Mississippi to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$264Average$448FlexibilityNo cancel feeOn-time71%
DeltaCheapest$275Average$404FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$345Average$496FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$362Average$472FlexibilityNo cancel feeOn-time63%
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