$115+ Cheap flights from Knoxville to San Diego (TYS - SAN)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/10. Fares are subject to change and may not be available on all flights or dates of travel.
Find cheap flights from Knoxville to San Diego with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Knoxville McGhee Tyson to San Diego are usually found in January or February, booked 32 days in advance, depart on a Wednesday or Thursday and return on a Wednesday
Cheap flight deals from Knoxville to San Diego
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 25, 2025.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $229 (United Airlines) |
One-way from | $115 (American Airlines) |
Popular in | April |
Cheapest in | January |
Average price | $468 |
Find flight deals from Knoxville to San Diego
Cheapest flights from Knoxville to San DiegoExplore the most affordable flight options available from Knoxville to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 25, 2025.
Explore the most affordable flight options available from Knoxville to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 25, 2025.
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Mytrip deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This American Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This CheapOair deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Alaska Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 25, 2025.
Use the filters below to find and compare flights from Knoxville to San Diego that are best for you.
Fly from
Fly to
Route
Depart
Return
Price
KnoxvilleSan Diego
TYS - SAN
TYSSAN
Knoxville McGhee Tyson
Wed 5/7
5:35 pm-10:14 pm
1 stop7h 39m
San Diego
Tue 5/13
10:26 am-8:06 pm
1 stop6h 40m
KnoxvilleSan Diego
TYS - SAN
TYSSAN
Knoxville McGhee Tyson
Mon 4/28
10:53 am-12:42 am
2 stops40h 49m
San Diego
Fri 5/2
6:15 am-9:59 pm
1 stop12h 44m
KnoxvilleSan Diego
TYS - SAN
TYSSAN
Knoxville McGhee Tyson
Tue 5/6
6:30 am-1:10 pm
1 stop9h 40m
San Diego
Tue 5/13
6:15 am-3:17 pm
1 stop6h 02m
KnoxvilleSan Diego
TYS - SAN
TYSSAN
Knoxville McGhee Tyson
Sat 4/5
5:24 am-10:10 am
1 stop7h 46m
San Diego
Wed 4/9
2:41 pm-11:55 pm
1 stop6h 14m
KnoxvilleSan Diego
TYS - SAN
TYSSAN
Knoxville McGhee Tyson
Fri 4/4
5:24 am-10:01 am
1 stop7h 37m
San Diego
Mon 4/7
6:15 am-11:30 pm
2 stops14h 15m
KnoxvilleSan Diego
TYS - SAN
TYSSAN
Knoxville McGhee Tyson
Sat 5/10
5:05 am-9:12 am
1 stop7h 07m
KnoxvilleSan Diego
TYS - SAN
TYSSAN
Knoxville McGhee Tyson
Sat 5/10
7:00 am-3:38 pm
2 stops11h 38m
KnoxvilleSan Diego
TYS - SAN
TYSSAN
Knoxville McGhee Tyson
Sun 3/30
2:50 pm-11:51 pm
2 stops36h 01m
KnoxvilleSan Diego
TYS - SAN
TYSSAN
Knoxville McGhee Tyson
Sun 3/30
4:43 pm-12:20 am
1 stop10h 37m
Compare providers for flights from Knoxville to San Diego
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to San Diego in March.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Knoxville-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-San Diego flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from Knoxville with our price prediction graph.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to San Diego
How far ahead should I book a flight from Knoxville to San Diego?
Use this chart to determine the optimal time to book a round-trip flight from Knoxville to San Diego. Price data was last updated on March 21, 2025.
The best time to book flights from Knoxville to San Diego is 32 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Knoxville to San Diego?
Currently, August is the cheapest month in which you can book a flight from Knoxville to San Diego (average of $286). Flying from Knoxville to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from TYS to SAN?
Find hourly flight availability from Knoxville to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 25, 2025.
A simple way to save on the total cost of your ticket is to fly from Knoxville to San Diego in the evening. If you’re flexible enough to do this you can expect to save up to 17% on your trip compared to booking a flight in the morning.
What is the cheapest day to fly from Knoxville to San Diego?
Use this chart to determine the cheapest time to fly round-trip from Knoxville to San Diego. Price data was last updated on December 16, 2024.
Travelers seeking maximum savings on their Knoxville to San Diego flight should consider departing on Friday evenings when fares are most often at their lowest. Sunday mornings flights should be avoided if possible as fares are typically the most expensive at this time.
Rainfall in San Diego by month
Plan your trip to San Diego by taking into account the average rainfall totals by month.
In terms of precipitation, rainfall in San Diego ranges from 0.0 - 2.3 inches per month. February is typically the wettest month, when rainfall can reach 2.3 in. July is typically the driest time to visit San Diego when rainfall is around 0.0 in.
Temperature in San Diego by month
Plan your trip to San Diego by taking into account the average temperature totals by month.
If weather is an important factor for your trip to San Diego, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 57.2 F).
Reviews of airlines servicing San Diego
Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated March 25, 2025.
Get a feel of what it's like to fly with Alaska Airlines, Delta and United Airlines from Knoxville to San Diego by reading reviews from past customers. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
Entertainment
Comfort
Overall
Food
Crew
Reviews
Seleste,Dec 2024
FAT - SAN
Boarding
Entertainment
Comfort
Overall
Food
Crew
Reviews
Seleste,Dec 2024
FAT - SAN
Boarding
Entertainment
Comfort
Overall
Food
Crew
Reviews
Seleste,Dec 2024
FAT - SAN
Boarding
Entertainment
Comfort
Overall
Food
Crew
Reviews
Seleste,Dec 2024
FAT - SAN
Boarding
Entertainment
Comfort
Overall
Food
Crew
Reviews
Seleste,Dec 2024
FAT - SAN
Boarding
Entertainment
Comfort
Overall
Food
Crew
Reviews
Seleste,Dec 2024
FAT - SAN
Related info for your journey
Find useful and relevant information for your journey from Knoxville to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Knoxville to San Diego
See prices for flight routes from nearby airports that may be better suited for you.
Top 5 airlines flying from Knoxville to San Diego
Discover the top 5 airlines that operate flights from Knoxville to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 25, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$150 | Average$235 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$256 | Average$415 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$258 | Average$449 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$282 | Average$394 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$366 | Average$567 | FlexibilityNo cancel fee | On-time75% |