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$369+ Cheap flights from Key West to San Diego (EYW - SAN)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/1. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — SAN
Apr 21 — Apr 281
Mon 4/21
Mon 4/28
1 adult, Economy
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1. Tell us where you want to go

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Cheap flight deals from Key West to San Diego

Discover tips and strategies to find the most affordable flight options for your journey from Key West (EYW) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 16, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$369
(American Airlines)
Provider with most accurate pricing for Key West-San Diego flight deals.
Search Deals
Provider most trusted by Cheapflights users for Key West-San Diego flights.
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From Key West to San Diego
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Find flight deals from Key West to San Diego

Cheapest flights from Key West to San Diego
Explore the most affordable flight options available from Key West to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 16, 2025.

This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/13:56 pmEYW - SAN
1 stop9h 42mAmerican Airlines
Mon 5/56:15 amSAN - EYW
1 stop7h 25mAmerican Airlines
Deal found 4/15$369
This United Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/18:45 amEYW - SAN
2 stops15h 37mUnited Airlines
Mon 5/56:34 pmSAN - EYW
3 stops20h 31mUnited Airlines
Deal found 4/15$562

Cheapflights Fare Finder

Customize your flight search to find flights from Key West to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 16, 2025.
Use the filters below to find and compare flights from Key West to San Diego that are best for you.

Fly from

Key West

Fly to

San Diego

Route

Depart

Return

Price

Key WestSan Diego

EYW - SAN

EYWSAN

Key West

Thu 5/1

3:56 pm-10:38 pm

1 stop9h 42m

San Diego

Mon 5/5

6:15 am-4:40 pm

1 stop7h 25m

$369

Key WestSan Diego

EYW - SAN

EYWSAN

Key West

Thu 5/1

8:45 am-9:22 pm

2 stops15h 37m

San Diego

Mon 5/5

6:34 pm-6:05 pm

3 stops20h 31m

$562

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/15

Compare providers for flights from Key West to San Diego

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Key West to San Diego in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*2 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Key West-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Key West-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Key West-San Diego flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Key West-San Diego flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Key West-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Key West to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Key West with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Key West to San Diego

What is the cheapest time of day to fly from EYW to SAN?

Find hourly flight availability from Key West to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 16, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 36% on flights from Key West to San Diego by exploring options for tickets in the afternoon.

Rainfall in San Diego by month

Plan your trip to San Diego by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in San Diego ranges from 0.0 - 2.3 inches per month. February is typically the wettest month, when rainfall can reach 2.3 in. July is typically the driest time to visit San Diego when rainfall is around 0.0 in.

Temperature in San Diego by month

Plan your trip to San Diego by taking into account the average temperature totals by month.

If weather is an important factor for your trip to San Diego, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 57.2 F).

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated April 16, 2025.
United Airlines
7.4
Good
8,665 reviews

Boarding

7.7

Comfort

7.3

Overall

7.4

Food

6.6

Entertainment

7.1

Crew

8.1

Reviews

1 / 20
4.0
Okay

Simon,Jun 2024

LAS - LAX

Basic and no-frills. Late timing put pressure on disembarking and making connections.
United Airlines
7.4
Good
8,665 reviews
United Airlines
7.4
Good
8,665 reviews

Boarding

7.7

Comfort

7.3

Overall

7.4

Food

6.6

Entertainment

7.1

Crew

8.1

Reviews

1 / 20
4.0
Okay

Simon,Jun 2024

LAS - LAX

Basic and no-frills. Late timing put pressure on disembarking and making connections.
American Airlines
7.2
Good
10,000 reviews
United Airlines
7.4
Good
8,665 reviews

Boarding

7.7

Comfort

7.3

Overall

7.4

Food

6.6

Entertainment

7.1

Crew

8.1

Reviews

1 / 20
4.0
Okay

Simon,Jun 2024

LAS - LAX

Basic and no-frills. Late timing put pressure on disembarking and making connections.

Related info for your journey

Find useful and relevant information for your journey from Key West to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Key West to San Diego round-trip?

    According to our current data, American Airlines ($369), and United Airlines ($562) offers the cheapest pricing from Key West to San Diego.

  • Can I find deals for flights from Key West to San Diego that include hotel bookings?

    Yes. In addition to deals on Key West to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Key West to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key West to San Diego.

  • Can I find deals for business class flights from Key West to San Diego?

    Yes. Cheapflights offers flight deals from Key West to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Key West to San Diego?

    Currently, August is the cheapest month in which you can book a flight from Key West to San Diego (average of $286). Flying from Key West to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
El Cajon
Chula Vista
Lemon Grove
National City
Imperial Beach
La Mesa
Alpine
Poway
Santee
Coronado

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Top airline flying from Key West to San Diego

Discover the top airline that operate flights from Key West to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$299Average$447FlexibilityNo cancel feeOn-time71%

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