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$115+ Cheap flights from Iowa to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/14. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SAN
Apr 5 — Apr 121
Sat 4/5
Sat 4/12
1 adult, Economy
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Cheap flight deals from Iowa to San Diego

Keep the following information in mind while searching for Iowa to San Diego flight deals. Data was last updated March 31, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$182
(Mytrip)

One-way from

$115
(American Airlines)

Popular in

March

Cheapest in

June

Average price

$532

Good round-trip deal

$170 or less
Provider with most accurate pricing for Des Moines-San Diego flight deals.
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Provider most trusted by Cheapflights users for Des Moines-San Diego flights.
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From Iowa to San Diego
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One-way flight from Iowa to San Diego
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Highest demand for flights based on searches. 15% potential increase in price ($69 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($14 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Price to beat on a round-trip flight from Iowa to San Diego.
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Find flight deals from Iowa to San Diego

Cheapest flights from Iowa to San Diego
Explore the most affordable flight options available from Iowa to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 31, 2025.

This Mytrip deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1412:20 pmCID - SAN
1 stop21h 14mMultiple Airlines
Thu 4/178:29 amSAN - CID
1 stop25h 01mMultiple Airlines
Deal found 3/30$182
This Mytrip deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/231:21 pmDSM - SAN
1 stop24h 47mMultiple Airlines
Fri 5/305:09 pmSAN - DSM
Nonstop3h 24mMultiple Airlines
Deal found 3/30$224
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/293:24 pmMLI - SAN
1 stop8h 30mAmerican Airlines
Tue 5/1310:19 amSAN - MLI
1 stop9h 26mAmerican Airlines
Deal found 3/30$229
This United Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/78:05 amCID - SAN
1 stop7h 41mUnited Airlines
Wed 5/1411:10 amSAN - CID
1 stop7h 31mUnited Airlines
Deal found 3/31$229
This Frontier deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/257:27 pmDSM - SAN
1 stop6h 47mFrontier
Wed 4/306:25 amSAN - DSM
1 stop10h 12mFrontier
Deal found 3/31$238
This Frontier deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/19:02 pmOMA - SAN
1 stop5h 11mFrontier
Sun 5/46:25 amSAN - OMA
1 stop11h 37mFrontier
Deal found 3/30$238
This Frontier deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/108:26 pmCID - SAN
1 stop5h 48mFrontier
Thu 5/16:25 amSAN - CID
1 stop10h 46mFrontier
Deal found 3/30$258
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/262:34 pmCID - SAN
1 stop5h 54mAmerican Airlines
Fri 5/24:30 pmSAN - CID
1 stop5h 26mAmerican Airlines
Deal found 3/30$259
This United Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/105:35 pmMLI - SAN
1 stop6h 39mUnited Airlines
Wed 6/188:30 pmSAN - MLI
2 stops11h 50mUnited Airlines
Deal found 3/30$262
This Mytrip deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1611:41 amOMA - SAN
2 stops31h 04mMultiple Airlines
Sun 5/185:43 pmSAN - OMA
1 stop15h 08mMultiple Airlines
Deal found 3/30$269
This Delta deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/76:00 amMLI - SAN
1 stop8h 33mDelta
Sat 5/171:58 pmSAN - MLI
1 stop6h 59mDelta
Deal found 3/29$277
This Delta deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/74:11 pmCID - SAN
1 stop6h 26mDelta
Sat 5/1712:40 pmSAN - CID
1 stop8h 21mDelta
Deal found 3/29$277

Cheapflights Fare Finder

Customize your flight search to find flights from Iowa to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2025.
Use the filters below to find and compare flights from Iowa to San Diego that are best for you.

Fly from

Iowa

Fly to

San Diego

Route

Depart

Return

Price

Cedar RapidsSan Diego

CID - SAN

CIDSAN

Cedar Rapids

Mon 4/14

12:20 pm-7:34 am

1 stop21h 14m

San Diego

Thu 4/17

8:29 am-11:30 am

1 stop25h 01m

$182

Des MoinesSan Diego

DSM - SAN

DSMSAN

Des Moines

Fri 5/23

1:21 pm-12:08 pm

1 stop24h 47m

San Diego

Fri 5/30

5:09 pm-10:33 pm

Nonstop3h 24m

$224

MolineSan Diego

MLI - SAN

MLISAN

Moline Quad-City

Tue 4/29

3:24 pm-9:54 pm

1 stop8h 30m

San Diego

Tue 5/13

10:19 am-9:45 pm

1 stop9h 26m

$229

Cedar RapidsSan Diego

CID - SAN

CIDSAN

Cedar Rapids

Wed 5/7

8:05 am-1:46 pm

1 stop7h 41m

San Diego

Wed 5/14

11:10 am-8:41 pm

1 stop7h 31m

$229

Des MoinesSan Diego

DSM - SAN

DSMSAN

Des Moines

Fri 4/25

7:27 pm-12:14 am

1 stop6h 47m

San Diego

Wed 4/30

6:25 am-6:37 pm

1 stop10h 12m

$238

OmahaSan Diego

OMA - SAN

OMASAN

Omaha Eppley Airfield

Thu 5/1

9:02 pm-12:13 am

1 stop5h 11m

San Diego

Sun 5/4

6:25 am-8:02 pm

1 stop11h 37m

$238

Cedar RapidsSan Diego

CID - SAN

CIDSAN

Cedar Rapids

Thu 4/10

8:26 pm-12:14 am

1 stop5h 48m

San Diego

Tue 4/29

6:25 am-7:14 pm

1 stop10h 49m

$258

Cedar RapidsSan Diego

CID - SAN

CIDSAN

Cedar Rapids

Sat 4/26

2:34 pm-6:28 pm

1 stop5h 54m

San Diego

Fri 5/2

4:30 pm-11:56 pm

1 stop5h 26m

$259

MolineSan Diego

MLI - SAN

MLISAN

Moline Quad-City

Tue 6/10

5:35 pm-10:14 pm

1 stop6h 39m

San Diego

Wed 6/18

8:30 pm-10:20 am

2 stops11h 50m

$262

OmahaSan Diego

OMA - SAN

OMASAN

Omaha Eppley Airfield

Fri 5/16

11:41 am-4:45 pm

2 stops31h 04m

San Diego

Sun 5/18

5:43 pm-10:51 am

1 stop15h 08m

$269

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/30

Showing 1-10 of 41 results
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Best time to book a flight from Iowa to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to San Diego

What is the cheapest month to book a flight from Iowa to San Diego?

Currently, August is the cheapest month in which you can book a flight from Iowa to San Diego (average of $286). Flying from Iowa to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to SAN?

Find hourly flight availability from Iowa to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 31, 2025.

When flying from Iowa to San Diego, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in San Diego by month

Plan your trip to San Diego by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in San Diego ranges from 0.0 - 2.3 inches per month. February is typically the wettest month, when rainfall can reach 2.3 in. July is typically the driest time to visit San Diego when rainfall is around 0.0 in.

Temperature in San Diego by month

Plan your trip to San Diego by taking into account the average temperature totals by month.

If weather is an important factor for your trip to San Diego, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 57.2 F).

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated March 31, 2025.
Read through reviews of airlines operating flights from Iowa to San Diego, such as Alaska Airlines, Southwest and Delta. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
9,818 reviews

Food

7.1

Overall

8.0

Entertainment

7.1

Comfort

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Seleste,Dec 2024

FAT - SAN

The attention and efficiency of the staff and the good handling of the pilot
Alaska Airlines
8.0
Very good
9,818 reviews
Alaska Airlines
8.0
Very good
9,818 reviews

Food

7.1

Overall

8.0

Entertainment

7.1

Comfort

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Seleste,Dec 2024

FAT - SAN

The attention and efficiency of the staff and the good handling of the pilot
Southwest
8.0
Very good
4,276 reviews
Alaska Airlines
8.0
Very good
9,818 reviews

Food

7.1

Overall

8.0

Entertainment

7.1

Comfort

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Seleste,Dec 2024

FAT - SAN

The attention and efficiency of the staff and the good handling of the pilot
Delta
8.0
Very good
7,899 reviews
Alaska Airlines
8.0
Very good
9,818 reviews

Food

7.1

Overall

8.0

Entertainment

7.1

Comfort

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Seleste,Dec 2024

FAT - SAN

The attention and efficiency of the staff and the good handling of the pilot
United Airlines
7.4
Good
8,614 reviews
Alaska Airlines
8.0
Very good
9,818 reviews

Food

7.1

Overall

8.0

Entertainment

7.1

Comfort

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Seleste,Dec 2024

FAT - SAN

The attention and efficiency of the staff and the good handling of the pilot
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
9,818 reviews

Food

7.1

Overall

8.0

Entertainment

7.1

Comfort

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Seleste,Dec 2024

FAT - SAN

The attention and efficiency of the staff and the good handling of the pilot

Related info for your journey

Find useful and relevant information for your journey from Iowa to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Diego from Iowa?

    San Diego (SAN) is the airport you will fly into if you book a flight from Iowa to San Diego. It is only a 2.6 mi journey from San Diego (SAN) to San Diego’s city center.

  • What are the cheapest airlines to fly from Iowa to San Diego one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $115. However, be on the lookout for offers from Frontier and Delta, as they are both options that can get you from Iowa to San Diego for a low price.

  • What are the most popular routes from Iowa to San Diego?

    The most popular route from Iowa to San Diego is Omaha Eppley Airfield - San Diego. You may also consider Cedar Rapids - San Diego or Moline Quad-City - San Diego.

  • What are the cheapest flights from Iowa to San Diego?

    While on average a flight from Iowa to San Diego is generally $180, our data shows the cheapest flight currently is $76. When looking at the most popular route, (Omaha Eppley Airfield - San Diego), you can expect to pay $208 for that flight.

  • Can I find deals for flights from Iowa to San Diego that include hotel bookings?

    Yes. In addition to deals on Iowa to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to San Diego.

  • Can I find deals for business class flights from Iowa to San Diego?

    Yes. Cheapflights offers flight deals from Iowa to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to San Diego?

    Currently, August is the cheapest month in which you can book a flight from Iowa to San Diego (average of $286). Flying from Iowa to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Iowa?

Book flights to Iowa if you plan to visit one of these locations
El Cajon
Chula Vista
Lemon Grove
National City
Imperial Beach
La Mesa
Alpine
Poway
Santee
Coronado
Borrego Springs

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Alternative routes for Iowa to San Diego

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from Iowa to San Diego

Discover the top 6 airlines that operate flights from Iowa to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$110Average$213FlexibilityNo cancel feeOn-time62%
Allegiant AirCheapest$140Average$202FlexibilityNo cancel feeOn-time88%
American AirlinesCheapest$250Average$403FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$263Average$437FlexibilityNo cancel feeOn-time69%
DeltaCheapest$276Average$382FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$359Average$474FlexibilityNo cancel feeOn-time63%
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