HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
San Diego

$121+ Cheap flights from Florida Keys to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/11. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — SAN
Nov 19 — Nov 261
Tue 11/19
Tue 11/26
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Florida Keys to San Diego with Cheapflights

1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”
2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.
3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Florida Keys to San Diego

Discover tips and strategies to find the most affordable flight options for your journey from Florida Keys (zzEOA) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 14, 2024.

Find flight deals from Florida Keys to San Diego

Cheapest flights from Florida Keys to San Diego
Explore the most affordable flight options available from Florida Keys to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 14, 2024.

This FareScan deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FareScan is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/219:20 pmMIA - SAN
1 stop12h 20mSpirit Airlines
Mon 11/2510:27 pmSAN - MIA
1 stop17h 47mSpirit Airlines
Deal found 11/12$251
This eDestinos deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/213:07 pmMIA - SAN
2 stops18h 33mMultiple Airlines
Tue 12/36:25 amSAN - MIA
2 stops29h 31mMultiple Airlines
Deal found 11/13$263
This American Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/177:23 pmEYW - SAN
1 stop7h 23mAmerican Airlines
Fri 1/37:23 amSAN - EYW
1 stop9h 06mAmerican Airlines
Deal found 11/13$283
This Delta deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/217:10 amMIA - SAN
1 stop7h 28mDelta
Sun 11/2410:10 pmSAN - MIA
1 stop9h 22mDelta
Deal found 11/13$286
This American Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/129:00 pmMIA - SAN
Nonstop5h 46mAmerican Airlines
Tue 12/3110:30 pmSAN - MIA
Nonstop4h 51mAmerican Airlines
Deal found 11/13$297
This flugladen.de deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure flugladen.de is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/288:06 pmMIA - SAN
Nonstop5h 52mAlaska Airlines
Sat 12/710:30 pmSAN - MIA
Nonstop4h 51mAlaska Airlines
Deal found 11/12$414
This United deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2210:55 amEYW - SAN
2 stops32h 10mUnited Airlines
Thu 1/26:47 pmSAN - EYW
2 stops21h 08mUnited Airlines
Deal found 11/13$481
This Alaska Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1711:09 amEYW - SAN
2 stops23h 27mAlaska Airlines
Fri 1/36:15 amSAN - EYW
3 stops26h 42mAlaska Airlines
Deal found 11/13$1,158

Find flights from Florida Keys to San Diego within your budget

Customize your flight search to find flights from Florida Keys to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,728,912 searches. Data last updated November 14, 2024.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

MiamiSan Diego

MIA - SAN

MIASAN

Miami

Fri 1/24

9:13 pm-5:59 pm

2 stops23h 46m

San Diego

Sat 2/1

6:15 am-10:13 pm

1 stop12h 58m

$250

MiamiSan Diego

MIA - SAN

MIASAN

Miami

Tue 1/7

3:00 pm-11:49 pm

1 stop11h 49m

San Diego

Tue 1/14

6:25 am-11:23 pm

1 stop13h 58m

$258

MiamiSan Diego

MIA - SAN

MIASAN

Miami

Fri 12/6

9:00 pm-11:46 pm

Nonstop5h 46m

San Diego

Tue 12/10

7:15 pm-6:57 am

1 stop8h 42m

$265

Key WestSan Diego

EYW - SAN

EYWSAN

Key West

Tue 12/17

7:23 pm-11:46 pm

1 stop7h 23m

San Diego

Fri 1/3

7:23 am-7:29 pm

1 stop9h 06m

$283

MiamiSan Diego

MIA - SAN

MIASAN

Miami

Sun 11/24

6:00 am-11:38 am

1 stop8h 38m

San Diego

Thu 11/28

6:30 am-5:43 pm

1 stop8h 13m

$286

MiamiSan Diego

MIA - SAN

MIASAN

Miami

Thu 12/12

9:00 pm-11:46 pm

Nonstop5h 46m

San Diego

Tue 12/31

10:30 pm-6:21 am

Nonstop4h 51m

$297

MiamiSan Diego

MIA - SAN

MIASAN

Miami

Fri 2/28

4:52 pm-9:33 pm

1 stop7h 41m

San Diego

Mon 3/3

5:25 pm-11:33 am

2 stops15h 08m

$361

MiamiSan Diego

MIA - SAN

MIASAN

Miami

Wed 4/30

5:55 pm-9:52 am

1 stop18h 57m

San Diego

Thu 5/15

6:50 pm-4:55 pm

1 stop19h 05m

$408

Key WestSan Diego

EYW - SAN

EYWSAN

Key West

Sun 12/22

10:55 am-4:05 pm

2 stops32h 10m

San Diego

Thu 1/2

6:47 pm-6:55 pm

2 stops21h 08m

$481

Key WestSan Diego

EYW - SAN

EYWSAN

Key West

Tue 12/17

11:09 am-7:36 am

2 stops23h 27m

San Diego

Fri 1/3

6:15 am-11:57 am

3 stops26h 42m

$1,158

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/12

Showing 1-10 of 22 results
1
2
3

Best time to book a flight from Florida Keys to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Florida Keys with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Florida Keys to San Diego

Get recent, data-driven insights about flights from Florida Keys to San Diego including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Florida Keys to San Diego?

Currently, September is the cheapest month in which you can book a flight from Florida Keys to San Diego (average of $266). Flying from Florida Keys to San Diego in March is currently the most expensive (average of $339). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from EOA to SAN?

Find hourly flight availability from Florida Keys to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 14, 2024.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Florida Keys to San Diego as you normally would.

Rainfall in San Diego by month

Plan your trip to San Diego by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in San Diego ranges from 0.0 - 2.3 inches per month. February is typically the wettest month, when rainfall can reach 2.3 in. July is typically the driest time to visit San Diego when rainfall is around 0.0 in.

Temperature in San Diego by month

Plan your trip to San Diego by taking into account the average temperature totals by month.

If weather is an important factor for your trip to San Diego, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 57.2 F).

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated November 14, 2024.
See what other customers who have flown with Alaska Airlines, Spirit Airlines and American Airlines from Florida Keys to San Diego have to say. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
5,046 reviews

Crew

8.7

Entertainment

7.7

Boarding

8.3

Comfort

8.1

Food

7.2

Overall

8.1

Reviews

1 / 10

No issues. I needed pre boarding and I was able to get it without issue

Southwest
8.1
Very good
5,046 reviews
Southwest
8.1
Very good
5,046 reviews

Crew

8.7

Entertainment

7.7

Boarding

8.3

Comfort

8.1

Food

7.2

Overall

8.1

Reviews

1 / 10

No issues. I needed pre boarding and I was able to get it without issue

Alaska Airlines
8.0
Very good
9,434 reviews
Southwest
8.1
Very good
5,046 reviews

Crew

8.7

Entertainment

7.7

Boarding

8.3

Comfort

8.1

Food

7.2

Overall

8.1

Reviews

1 / 10

No issues. I needed pre boarding and I was able to get it without issue

Delta
8.0
Very good
8,787 reviews
Southwest
8.1
Very good
5,046 reviews

Crew

8.7

Entertainment

7.7

Boarding

8.3

Comfort

8.1

Food

7.2

Overall

8.1

Reviews

1 / 10

No issues. I needed pre boarding and I was able to get it without issue

JetBlue
7.5
Good
3,448 reviews
Southwest
8.1
Very good
5,046 reviews

Crew

8.7

Entertainment

7.7

Boarding

8.3

Comfort

8.1

Food

7.2

Overall

8.1

Reviews

1 / 10

No issues. I needed pre boarding and I was able to get it without issue

United Airlines
7.4
Good
9,186 reviews
Southwest
8.1
Very good
5,046 reviews

Crew

8.7

Entertainment

7.7

Boarding

8.3

Comfort

8.1

Food

7.2

Overall

8.1

Reviews

1 / 10

No issues. I needed pre boarding and I was able to get it without issue

Related info for your journey

Find useful and relevant information for your journey from Florida Keys to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Diego from Florida Keys?

    San Diego (SAN), located 2.6 mi from the city center, is the airport you fly into when you book flights from Florida Keys to San Diego.

  • What are the cheapest airlines to fly from Florida Keys to San Diego one-way?

    The cheapest airlines for a one-way flight from Florida Keys to San Diego are Frontier ($123), Spirit Airlines ($125), and American Airlines ($134).

  • Can I find deals for flights from Florida Keys to San Diego that include hotel bookings?

    Yes. In addition to deals on Florida Keys to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florida Keys to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florida Keys to San Diego.

  • Can I find deals for business class flights from Florida Keys to San Diego?

    Yes. Cheapflights offers flight deals from Florida Keys to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Florida Keys to San Diego?

    Currently, September is the cheapest month in which you can book a flight from Florida Keys to San Diego (average of $266). Flying from Florida Keys to San Diego in March is currently the most expensive (average of $339). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Florida Keys to San Diego

See prices for flight routes from nearby airports that may be better suited for you.
Miami to Los Angeles flights
Fort Lauderdale to Los Angeles flights
Orlando to Las Vegas flights
Orlando to Los Angeles flights
Fort Lauderdale to Las Vegas flights
Tampa to Las Vegas flights
Miami to Las Vegas flights
Tampa to Los Angeles flights
Miami to San Francisco flights
Fort Lauderdale to Burbank flights
Orlando to San Francisco flights
Miami to Ontario flights
Fort Lauderdale to Santa Ana flights
Fort Lauderdale to San Francisco flights
West Palm Beach to Los Angeles flights
Tampa to San Francisco flights
Orlando to Ontario flights
Fort Lauderdale to Ontario flights
Miami to Burbank flights
Miami to Santa Ana flights
Orlando to Burbank flights
West Palm Beach to Las Vegas flights
Fort Lauderdale to San Diego flights
Orlando to San Diego flights
Orlando to Santa Ana flights
Fort Lauderdale to Oakland flights
Tampa to Ontario flights
Miami to San Diego flights
Jacksonville to Los Angeles flights
Jacksonville to Las Vegas flights
Fort Myers to Las Vegas flights
Tampa to San Diego flights
Tampa to Burbank flights
Sarasota to Las Vegas flights
Tampa to Santa Ana flights
West Palm Beach to Ontario flights
Fort Lauderdale to San Jose flights
Orlando to San Jose flights
Pensacola to Las Vegas flights
Miami to Oakland flights
Jacksonville to San Francisco flights
Panama City to Las Vegas flights
Orlando to Oakland flights
Jacksonville to Ontario flights
Tampa to Oakland flights
Pensacola to Los Angeles flights
West Palm Beach to San Francisco flights
Orlando to Sacramento flights
Orlando to Palm Springs flights
Miami to San Jose flights

Top airline flying from Florida Keys to San Diego

Discover the top airline that operate flights from Florida Keys to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,728,912 searches. Data last updated November 14, 2024.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$261Average$366FlexibilityNo cancel feeOn-time71%
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.
View all available airlines