What are the cheapest airlines flying from Panama City to San Antonio round-trip?

Currently priced at $494, Delta will fly you from Panama City to San Antonio and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from American Airlines and United Airlines - these airlines can fly you to your destination from $507 and $558, respectively. These flights start at 11% lower than the current average price 3 months from now.

What is the cheapest day to fly from Panama City to San Antonio?

Travelers seeking maximum savings on their Panama City to San Antonio flight should consider departing on Monday evenings when fares are most often at their lowest. Friday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

What is the cheapest day to fly round-trip from Panama City to San Antonio?

Leaving on a Monday is a viable option for saving on travel. Heavily demanded days of the week can typically drive up the prices you see. Booking your travel for a less competitive day can save up to 29% on the overall cost on flights from Panama City to San Antonio.

How far in advance should I book a flight from Panama City to San Antonio?

To save on the cost of your flight from Panama City to San Antonio, book at least 52 days before your planned departure. Booking around this time can save you about 27% on the cost of this flight compared to booking a flight leaving this week. We have found prices from $548 if you need a flight within two weeks. For flights within the next 72 hours, you can find tickets from as low as $590.

What is the cheapest month to fly from Panama City to San Antonio?

Our data shows that August tends to be the cheapest month to fly to San Antonio from Panama City. Users have commonly found prices around $557 for the month, but tickets can be as low as $375. Due to multiple factors, prepare for potentially higher prices in January.

Most accurate provider : When it comes to deals on Panama City-San Antonio flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-San Antonio flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-San Antonio flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Panama City-San Antonio flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-San Antonio flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Panama City to San Antonio that include hotel bookings?

Yes. In addition to deals on Panama City to San Antonio flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Panama City to San Antonio?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to San Antonio.

Can I find deals for business class flights from Panama City to San Antonio?

Yes. Cheapflights offers flight deals from Panama City to San Antonio by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$301+ Flights from Panama City to San Antonio

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1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

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Cheapflights Tip: The best prices from Panama City Tocumen Intl to San Antonio are usually found in August or May, booked 51 days in advance, depart on a Tuesday or Sunday and return on a Tuesday

Cheap flight deals from Panama City to San Antonio

Most accurate provider	FlightHub 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$494 (Delta)
One-way from	$301 (Delta)
Popular in	January
Cheapest in	August
Average price	$553

Provider with most accurate pricing for Panama City Tocumen Intl-San Antonio flight deals.

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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-San Antonio flights.

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From Panama City Tocumen Intl to San Antonio

Search Deals

One-way flight from Panama City Tocumen Intl to San Antonio

Search Deals

Highest demand for flights based on searches. 7% potential increase in price ($42 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 0% potential price decrease ($5 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in April 2025

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Find flight deals from Panama City to San Antonio

Cheapest flights from Panama City to San Antonio
Explore the most affordable flight options available from Panama City to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2025.

Thu 7/172:12 pmPTY - SAT

1 stop10h 02mDelta

Tue 8/55:30 amSAT - PTY

1 stop7h 24mDelta

Deal found 4/21

$494

Tue 6/101:50 pmPTY - SAT

2 stops24h 42mAmerican Airlines

Sun 6/156:31 pmSAT - PTY

2 stops19h 54mAmerican Airlines

Deal found 4/21

$507

Mon 5/193:25 amPTY - SAT

2 stops19h 26mMultiple Airlines

Tue 5/277:05 amSAT - PTY

2 stops17h 05mMultiple Airlines

Deal found 4/20

$536

Fri 5/307:55 amPTY - SAT

1 stop9h 47mUnited Airlines

Sat 6/287:19 pmSAT - PTY

1 stop20h 53mUnited Airlines

Deal found 4/22

$558

Best flights from Panama City to San Antonio
Discover carefully curated flight deals from Panama City to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 22, 2025.

Thu 7/172:12 pmPTY - SAT

1 stop10h 02mDelta

Tue 8/55:30 amSAT - PTY

1 stop7h 24mDelta

Deal found 4/21

$494

Tue 6/101:50 pmPTY - SAT

1 stop10h 09mAmerican Airlines

Sun 6/156:31 pmSAT - PTY

2 stops19h 54mAmerican Airlines

Deal found 4/21

$507

Mon 5/193:25 amPTY - SAT

2 stops19h 26mMultiple Airlines

Tue 5/277:05 amSAT - PTY

2 stops17h 05mMultiple Airlines

Deal found 4/20

$536

Fri 5/307:55 amPTY - SAT

1 stop9h 47mUnited Airlines

Sat 6/287:19 pmSAT - PTY

1 stop20h 53mUnited Airlines

Deal found 4/22

$558

Last-minute flights from Panama City to San Antonio
Discover last-minute flight deals from Panama City to San Antonio. Data last updated April 22, 2025 and is based on user searches.

Mon 5/193:25 amPTY - SAT

2 stops19h 26mMultiple Airlines

Tue 5/277:05 amSAT - PTY

2 stops17h 05mMultiple Airlines

Deal found 4/20

$536

Tue 5/202:13 pmPTY - SAT

1 stop10h 08mDelta

Tue 5/275:20 amSAT - PTY

1 stop7h 28mDelta

Deal found 4/21

$537

Tue 5/201:20 pmPTY - SAT

2 stops26h 29mAmerican Airlines

Tue 5/277:34 pmSAT - PTY

2 stops16h 45mAmerican Airlines

Deal found 4/21

$550

Fri 5/307:55 amPTY - SAT

1 stop9h 47mUnited Airlines

Sat 6/287:19 pmSAT - PTY

1 stop20h 53mUnited Airlines

Deal found 4/22

$558

One-way flights from Panama City to San Antonio
Search for one-way flight options from Panama City to San Antonio. Find affordable one-way fares based on user searches. Data last updated April 22, 2025.

Wed 6/252:23 pmPTY - SAT

1 stop9h 54mDelta

Deal found 4/22

$301

Wed 6/251:50 pmPTY - SAT

2 stops23h 27mAmerican Airlines

Deal found 4/22

$310

Sun 6/810:05 pmPTY - SAT

3 stops30h 59mMultiple Airlines

Deal found 4/21

$356

Cheapflights Fare Finder

Use the filters below to find and compare flights from Panama City to San Antonio that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Thu 7/17

2:12 pm-12:14 am

1 stop10h 02m

San Antonio

Tue 8/5

5:30 am-12:54 pm

1 stop7h 24m

$494

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Tue 6/10

1:50 pm-11:59 pm

1 stop10h 09m

San Antonio

Sun 6/15

6:31 pm-2:25 pm

2 stops19h 54m

$507

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Mon 5/19

3:25 am-10:51 pm

2 stops19h 26m

San Antonio

Tue 5/27

7:05 am-12:10 am

2 stops17h 05m

$536

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Fri 5/30

7:55 am-5:42 pm

1 stop9h 47m

San Antonio

Sat 6/28

7:19 pm-4:12 pm

1 stop20h 53m

$558

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Wed 6/25

2:23 pm-12:17 am

1 stop9h 54m

$301

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Wed 6/25

1:50 pm-1:17 pm

2 stops23h 27m

$310

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

Sun 6/8

10:05 pm-5:04 am

3 stops30h 59m

$356

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/22

Compare providers for flights from Panama City to San Antonio

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to San Antonio in April.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy1 star	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*2 stars
eDreams	Price Accuracy3 stars	Trust Score*3 stars
Priceline	Price Accuracy1 star	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Panama City-San Antonio flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-San Antonio flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-San Antonio flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Panama City-San Antonio flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-San Antonio flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to San Antonio

Have a flexible travel schedule? Discover the best time to fly to San Antonio from Panama City with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to San Antonio

How far ahead should I book a flight from Panama City to San Antonio?

The price you pay for your flight from Panama City to San Antonio may vary depending on when you book. For the best chance of a lower fare, look to book 51 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Panama City to San Antonio?

Currently, August is the cheapest month in which you can book a flight from Panama City to San Antonio (average of $295). Flying from Panama City to San Antonio in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to SAT?

It’s optimal to fly from Panama City to San Antonio in the afternoon. By choosing this option you can save up to 17% on the cost of your flight, compared to a flight at noon.

Rainfall in San Antonio by month

In terms of precipitation, rainfall in San Antonio ranges from 1.6 - 3.7 inches per month. May is typically the wettest month, when rainfall can reach 3.7 in. December is typically the driest time to visit San Antonio when rainfall is around 1.6 in.

Temperature in San Antonio by month

If weather is an important factor for your trip to San Antonio, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

Reviews of airlines servicing San Antonio

Delta

8.0

Very good

7,920 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta

8.0

Very good

7,920 reviews

Delta

8.0

Very good

7,920 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

United Airlines

7.4

Good

8,683 reviews

Delta

8.0

Very good

7,920 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,920 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

What are the cheapest airlines flying from Panama City to San Antonio round-trip?
Currently priced at $494, Delta will fly you from Panama City to San Antonio and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from American Airlines and United Airlines - these airlines can fly you to your destination from $507 and $558, respectively. These flights start at 11% lower than the current average price 3 months from now.
Can I find deals for flights from Panama City to San Antonio that include hotel bookings?
Yes. In addition to deals on Panama City to San Antonio flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Panama City to San Antonio?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to San Antonio.
Can I find deals for business class flights from Panama City to San Antonio?
Yes. Cheapflights offers flight deals from Panama City to San Antonio by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Panama City to San Antonio?
Currently, August is the cheapest month in which you can book a flight from Panama City to San Antonio (average of $295). Flying from Panama City to San Antonio in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Other flights to San Antonio

Top airline flying from Panama City to San Antonio

Airline	Cheapest	Average	Flexibility	On-time
United Airlines	Cheapest$469	Average$554	FlexibilityNo cancel fee	On-time69%

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$301+ Cheap flights from Panama City (PTY) to San Antonio (SAT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/25. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Panama City to San Antonio with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Panama City Tocumen Intl to San Antonio are usually found in August or May, booked 51 days in advance, depart on a Tuesday or Sunday and return on a Tuesday

Cheap flight deals from Panama City to San Antonio

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Panama City to San Antonio

Cheapest flights from Panama City to San AntonioExplore the most affordable flight options available from Panama City to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2025.

Explore the most affordable flight options available from Panama City to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Panama City to San Antonio that are best for you.

Compare providers for flights from Panama City to San Antonio

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to San Antonio in April.

Best time to book a flight from Panama City to San Antonio

Have a flexible travel schedule? Discover the best time to fly to San Antonio from Panama City with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Panama City to San Antonio

How far ahead should I book a flight from Panama City to San Antonio?

Use this chart to determine the optimal time to book a round-trip flight from Panama City to San Antonio. Price data was last updated on April 18, 2025.

What is the cheapest month to book a flight from Panama City to San Antonio?

What is the cheapest time of day to fly from PTY to SAT?

Find hourly flight availability from Panama City to San Antonio. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 22, 2025.

Rainfall in San Antonio by month

Plan your trip to San Antonio by taking into account the average rainfall totals by month.

Temperature in San Antonio by month

Plan your trip to San Antonio by taking into account the average temperature totals by month.

Reviews of airlines servicing San Antonio

Related info for your journey

Find useful and relevant information for your journey from Panama City to San Antonio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Panama City to San Antonio round-trip?

Can I find deals for flights from Panama City to San Antonio that include hotel bookings?

How can I find direct flights from Panama City to San Antonio?

Can I find deals for business class flights from Panama City to San Antonio?

What is the cheapest month to book a flight from Panama City to San Antonio?

Traveling to a place near Panama City?

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Alternative routes for Panama City to San Antonio

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Top airline flying from Panama City to San Antonio

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Cheapest flights from Panama City to San Antonio
Explore the most affordable flight options available from Panama City to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2025.