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$119+ Cheap flights from Knoxville to San Antonio (TYS - SAT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/2. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — SAT
Apr 16 — Apr 231
Wed 4/16
Wed 4/23
1 adult, Economy
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Cheapflights Tip: The best prices from Knoxville McGhee Tyson to San Antonio are usually found in January or August, booked 67 days in advance, depart on a Friday or Wednesday and return on a Wednesday

Cheap flight deals from Knoxville to San Antonio

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to San Antonio (SAT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 11, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$228
(Mytrip)

One-way from

$119
(Mytrip)

Popular in

March

Cheapest in

January

Average price

$380
Provider with most accurate pricing for Knoxville McGhee Tyson-San Antonio flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-San Antonio flights.
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From Knoxville McGhee Tyson to San Antonio
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One-way flight from Knoxville McGhee Tyson to San Antonio
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Highest demand for flights based on searches. 8% potential increase in price ($31 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($12 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Knoxville to San Antonio

Cheapest flights from Knoxville to San Antonio
Explore the most affordable flight options available from Knoxville to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 11, 2025.

This Mytrip deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/81:43 pmTYS - SAT
1 stop10h 08mMultiple Airlines
Thu 5/151:52 pmSAT - TYS
1 stop27h 20mMultiple Airlines
Deal found 4/10$228
This Delta deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/307:50 amTYS - SAT
1 stop8h 15mDelta
Fri 6/61:46 pmSAT - TYS
1 stop8h 18mDelta
Deal found 4/10$258
This American Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/146:25 pmTYS - SAT
1 stop5h 38mAmerican Airlines
Tue 6/1711:43 amSAT - TYS
1 stop6h 18mAmerican Airlines
Deal found 4/10$329
This United deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/137:00 amTYS - SAT
2 stops9h 46mUnited Airlines
Sat 5/176:06 pmSAT - TYS
1 stop4h 40mUnited Airlines
Deal found 4/10$334

Cheapflights Fare Finder

Customize your flight search to find flights from Knoxville to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 11, 2025.
Use the filters below to find and compare flights from Knoxville to San Antonio that are best for you.

Fly from

Knoxville

Fly to

San Antonio

Route

Depart

Return

Price

KnoxvilleSan Antonio

TYS - SAT

TYSSAT

Knoxville McGhee Tyson

Thu 5/8

1:43 pm-10:51 pm

1 stop10h 08m

San Antonio

Thu 5/15

1:52 pm-6:12 pm

1 stop27h 20m

$228

KnoxvilleSan Antonio

TYS - SAT

TYSSAT

Knoxville McGhee Tyson

Fri 5/30

7:50 am-3:05 pm

1 stop8h 15m

San Antonio

Fri 6/6

1:46 pm-11:04 pm

1 stop8h 18m

$258

KnoxvilleSan Antonio

TYS - SAT

TYSSAT

Knoxville McGhee Tyson

Sat 6/14

6:25 pm-11:03 pm

1 stop5h 38m

San Antonio

Tue 6/17

11:43 am-7:01 pm

1 stop6h 18m

$329

KnoxvilleSan Antonio

TYS - SAT

TYSSAT

Knoxville McGhee Tyson

Tue 5/13

7:00 am-3:46 pm

2 stops9h 46m

San Antonio

Sat 5/17

6:06 pm-11:46 pm

1 stop4h 40m

$334

KnoxvilleSan Antonio

TYS - SAT

TYSSAT

Knoxville McGhee Tyson

Fri 5/2

10:00 am-11:18 am

1 stop26h 18m

$119

KnoxvilleSan Antonio

TYS - SAT

TYSSAT

Knoxville McGhee Tyson

Tue 6/3

6:28 pm-11:02 pm

1 stop5h 34m

$201

KnoxvilleSan Antonio

TYS - SAT

TYSSAT

Knoxville McGhee Tyson

Tue 6/3

7:00 am-3:23 pm

2 stops9h 23m

$285

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/10

Compare providers for flights from Knoxville to San Antonio

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to San Antonio in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-San Antonio flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-San Antonio flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-San Antonio flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-San Antonio flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-San Antonio flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to San Antonio

Have a flexible travel schedule? Discover the best time to fly to San Antonio from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to San Antonio

How far ahead should I book a flight from Knoxville to San Antonio?

Use this chart to determine the optimal time to book a round-trip flight from Knoxville to San Antonio. Price data was last updated on April 4, 2025.

To ensure you get the cheapest price possible for a flight from Knoxville to San Antonio, you should look to book at least 67 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Knoxville to San Antonio?

Currently, August is the cheapest month in which you can book a flight from Knoxville to San Antonio (average of $295). Flying from Knoxville to San Antonio in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to SAT?

Find hourly flight availability from Knoxville to San Antonio. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 11, 2025.

It’s optimal to fly from Knoxville to San Antonio in the evening. By choosing this option you can save up to 19% on the cost of your flight, compared to a flight in the morning.

What is the cheapest day to fly from Knoxville to San Antonio?

Use this chart to determine the cheapest time to fly round-trip from Knoxville to San Antonio. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Knoxville to San Antonio flight should consider departing on Wednesday at noon when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Rainfall in San Antonio by month

Plan your trip to San Antonio by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in San Antonio ranges from 1.6 - 3.7 inches per month. May is typically the wettest month, when rainfall can reach 3.7 in. December is typically the driest time to visit San Antonio when rainfall is around 1.6 in.

Temperature in San Antonio by month

Plan your trip to San Antonio by taking into account the average temperature totals by month.

If weather is an important factor for your trip to San Antonio, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

Reviews of airlines servicing San Antonio

Get insights into the airlines that provide service to San Antonio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Antonio. Reviews last updated April 11, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines and American Airlines from Knoxville to San Antonio to help guide your decision. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,911 reviews

Food

7.3

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,911 reviews
Delta
8.0
Very good
7,911 reviews

Food

7.3

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,636 reviews
Delta
8.0
Very good
7,911 reviews

Food

7.3

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,911 reviews

Food

7.3

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Knoxville to San Antonio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Knoxville to San Antonio round-trip?

    Our cheapest airline available from Knoxville to San Antonio is Delta. Our recent data shows that you can find tickets from as low as $258 on this airline. Additional options worth looking into are American Airlines and United Airlines, starting at $329 and $334 round-trip. Delta is 25% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Knoxville to San Antonio that include hotel bookings?

    Yes. In addition to deals on Knoxville to San Antonio flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to San Antonio?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to San Antonio.

  • Can I find deals for business class flights from Knoxville to San Antonio?

    Yes. Cheapflights offers flight deals from Knoxville to San Antonio by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to San Antonio?

    Currently, August is the cheapest month in which you can book a flight from Knoxville to San Antonio (average of $295). Flying from Knoxville to San Antonio in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
New Braunfels

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Top 3 airlines flying from Knoxville to San Antonio

Discover the top 3 airlines that operate flights from Knoxville to San Antonio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$205Average$325FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$238Average$422FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$238Average$338FlexibilityNo cancel feeOn-time71%

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