HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
San Antonio

$139+ Cheap flights from Knoxville to San Antonio (TYS - SAT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/5. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — SAT
Mar 26 — Apr 21
Wed 3/26
Wed 4/2
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Knoxville to San Antonio with Cheapflights

1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”
2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.
3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Knoxville McGhee Tyson to San Antonio are usually found in January or August, booked 67 days in advance, depart on a Friday or Wednesday and return on a Wednesday

Cheap flight deals from Knoxville to San Antonio

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to San Antonio (SAT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 21, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$239
(Mytrip)

One-way from

$139
(Mytrip)

Popular in

December

Cheapest in

January

Average price

$382
Provider with most accurate pricing for Knoxville McGhee Tyson-San Antonio flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-San Antonio flights.
Search Deals
From Knoxville McGhee Tyson to San Antonio
Search Deals
One-way flight from Knoxville McGhee Tyson to San Antonio
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($9 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2025
Search Deals

Find flight deals from Knoxville to San Antonio

Cheapest flights from Knoxville to San Antonio
Explore the most affordable flight options available from Knoxville to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 21, 2025.

This Mytrip deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/114:12 pmTYS - SAT
1 stop24h 54mMultiple Airlines
Sun 4/138:29 pmSAT - TYS
1 stop20h 30mMultiple Airlines
Deal found 3/20$239
This Delta deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/105:45 amTYS - SAT
1 stop4h 52mDelta
Wed 5/145:20 amSAT - TYS
1 stop5h 03mDelta
Deal found 3/21$249
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/286:28 pmTYS - SAT
1 stop6h 30mAmerican Airlines
Fri 5/306:00 amSAT - TYS
1 stop4h 41mAmerican Airlines
Deal found 3/20$279
This United deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/101:57 pmTYS - SAT
2 stops8h 18mUnited Airlines
Wed 5/149:40 amSAT - TYS
2 stops12h 05mUnited Airlines
Deal found 3/20$394

Cheapflights Fare Finder

Customize your flight search to find flights from Knoxville to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 21, 2025.
Use the filters below to find and compare flights from Knoxville to San Antonio that are best for you.

Fly from

Knoxville

Fly to

San Antonio

Route

Depart

Return

Price

KnoxvilleSan Antonio

TYS - SAT

TYSSAT

Knoxville McGhee Tyson

Fri 4/11

4:12 pm-4:06 pm

1 stop24h 54m

San Antonio

Sun 4/13

8:29 pm-5:59 pm

1 stop20h 30m

$239

KnoxvilleSan Antonio

TYS - SAT

TYSSAT

Knoxville McGhee Tyson

Sat 5/10

5:45 am-9:37 am

1 stop4h 52m

San Antonio

Wed 5/14

5:20 am-11:23 am

1 stop5h 03m

$249

KnoxvilleSan Antonio

TYS - SAT

TYSSAT

Knoxville McGhee Tyson

Wed 5/28

6:28 pm-11:58 pm

1 stop6h 30m

San Antonio

Fri 5/30

6:00 am-11:41 am

1 stop4h 41m

$279

KnoxvilleSan Antonio

TYS - SAT

TYSSAT

Knoxville McGhee Tyson

Sat 5/10

10:50 am-5:54 pm

2 stops8h 04m

San Antonio

Sat 5/17

2:08 pm-11:07 pm

1 stop7h 59m

$334

KnoxvilleSan Antonio

TYS - SAT

TYSSAT

Knoxville McGhee Tyson

Sat 4/5

3:19 pm-10:03 am

1 stop19h 44m

$139

KnoxvilleSan Antonio

TYS - SAT

TYSSAT

Knoxville McGhee Tyson

Mon 5/26

5:45 am-9:37 am

1 stop4h 52m

$201

KnoxvilleSan Antonio

TYS - SAT

TYSSAT

Knoxville McGhee Tyson

Mon 5/26

5:45 am-10:59 pm

3 stops18h 14m

$422

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/20

Compare providers for flights from Knoxville to San Antonio

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to San Antonio in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-San Antonio flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-San Antonio flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-San Antonio flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-San Antonio flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-San Antonio flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to San Antonio

Have a flexible travel schedule? Discover the best time to fly to San Antonio from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to San Antonio

How far ahead should I book a flight from Knoxville to San Antonio?

Use this chart to determine the optimal time to book a round-trip flight from Knoxville to San Antonio. Price data was last updated on March 14, 2025.

To ensure you get the cheapest price possible for a flight from Knoxville to San Antonio, you should look to book at least 67 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Knoxville to San Antonio?

Currently, August is the cheapest month in which you can book a flight from Knoxville to San Antonio (average of $295). Flying from Knoxville to San Antonio in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to SAT?

Find hourly flight availability from Knoxville to San Antonio. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 21, 2025.

It’s optimal to fly from Knoxville to San Antonio in the evening. By choosing this option you can save up to 19% on the cost of your flight, compared to a flight in the morning.

What is the cheapest day to fly from Knoxville to San Antonio?

Use this chart to determine the cheapest time to fly round-trip from Knoxville to San Antonio. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Knoxville to San Antonio flight should consider departing on Wednesday at noon when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Rainfall in San Antonio by month

Plan your trip to San Antonio by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in San Antonio ranges from 1.6 - 3.7 inches per month. May is typically the wettest month, when rainfall can reach 3.7 in. December is typically the driest time to visit San Antonio when rainfall is around 1.6 in.

Temperature in San Antonio by month

Plan your trip to San Antonio by taking into account the average temperature totals by month.

If weather is an important factor for your trip to San Antonio, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

Reviews of airlines servicing San Antonio

Get insights into the airlines that provide service to San Antonio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Antonio. Reviews last updated March 21, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines and American Airlines from Knoxville to San Antonio to help guide your decision. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,895 reviews

Comfort

8.0

Overall

8.0

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,895 reviews
Delta
8.0
Very good
7,895 reviews

Comfort

8.0

Overall

8.0

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,605 reviews
Delta
8.0
Very good
7,895 reviews

Comfort

8.0

Overall

8.0

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,895 reviews

Comfort

8.0

Overall

8.0

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Knoxville to San Antonio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Knoxville to San Antonio round-trip?

    Our cheapest airline available from Knoxville to San Antonio is Delta. Our recent data shows that you can find tickets from as low as $249 on this airline. Additional options worth looking into are American Airlines and United Airlines, starting at $279 and $334 round-trip. Delta is 25% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Knoxville to San Antonio that include hotel bookings?

    Yes. In addition to deals on Knoxville to San Antonio flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to San Antonio?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to San Antonio.

  • Can I find deals for business class flights from Knoxville to San Antonio?

    Yes. Cheapflights offers flight deals from Knoxville to San Antonio by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to San Antonio?

    Currently, August is the cheapest month in which you can book a flight from Knoxville to San Antonio (average of $295). Flying from Knoxville to San Antonio in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
New Braunfels

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Knoxville to San Antonio

See prices for flight routes from nearby airports that may be better suited for you.
Nashville to Dallas/Fort Worth flights
Memphis to Hobby flights
Memphis to Dallas/Fort Worth flights
Memphis to George Bush Intcntl flights
Nashville to Hobby flights
Knoxville to Dallas/Fort Worth flights
Nashville to George Bush Intcntl flights
Nashville to Austin flights
Chattanooga to Dallas/Fort Worth flights
Nashville to Love Field flights
Memphis to Love Field flights
Nashville to San Antonio flights
Knoxville to Hobby flights
Chattanooga to Hobby flights
Knoxville to George Bush Intcntl flights
Chattanooga to George Bush Intcntl flights
Blountville to Dallas/Fort Worth flights
Memphis to San Antonio flights
Memphis to Austin flights
Chattanooga to Love Field flights
Chattanooga to Austin flights
Knoxville to Love Field flights
Nashville to Harlingen flights
Chattanooga to San Antonio flights
Nashville to El Paso flights
Knoxville to El Paso flights
Nashville to Amarillo flights
Memphis to Lubbock flights
Nashville to McAllen flights
Knoxville to Austin flights
Nashville to Lubbock flights
Blountville to Love Field flights
Blountville to Hobby flights
Blountville to San Antonio flights
Blountville to Austin flights
Memphis to El Paso flights
Nashville to Brownsville flights
Nashville to Killeen flights
Nashville to Waco flights
Memphis to Waco flights
Memphis to McAllen flights
Blountville to George Bush Intcntl flights
Knoxville to Waco flights
Nashville to Corpus Christi flights
Blountville to Corpus Christi flights
Nashville to Abilene flights
Nashville to College Station flights
Nashville to Wichita Falls flights
Chattanooga to Killeen flights

Top 3 airlines flying from Knoxville to San Antonio

Discover the top 3 airlines that operate flights from Knoxville to San Antonio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$205Average$323FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$238Average$403FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$238Average$328FlexibilityNo cancel feeOn-time71%
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.