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$126+ Cheap flights from Des Moines to San Antonio (DSM - SAT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/4. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SAT
Mar 31 — Apr 71
Mon 3/31
Mon 4/7
1 adult, Economy
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Cheapflights Tip: The best prices from Des Moines to San Antonio are usually found in July or August, booked 80 days in advance, depart on a Wednesday or Thursday and return on a Tuesday

Cheap flight deals from Des Moines to San Antonio

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to San Antonio (SAT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 26, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$297
(Delta)

One-way from

$126
(Mytrip)

Popular in

March

Cheapest in

July

Average price

$521
Provider with most accurate pricing for Des Moines-San Antonio flight deals.
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Provider most trusted by Cheapflights users for Des Moines-San Antonio flights.
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From Des Moines to San Antonio
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One-way flight from Des Moines to San Antonio
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Highest demand for flights based on searches. 15% potential increase in price ($69 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Find flight deals from Des Moines to San Antonio

Cheapest flights from Des Moines to San Antonio
Explore the most affordable flight options available from Des Moines to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 26, 2025.

This Delta deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/266:30 amDSM - SAT
1 stop6h 16mDelta
Tue 4/298:15 amSAT - DSM
1 stop5h 09mDelta
Deal found 3/25$297
This Mytrip deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/283:25 pmDSM - SAT
1 stop17h 49mMultiple Airlines
Sat 5/36:31 pmSAT - DSM
2 stops20h 23mMultiple Airlines
Deal found 3/25$298
This American Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/265:43 amDSM - SAT
2 stops7h 55mAmerican Airlines
Wed 4/306:22 pmSAT - DSM
1 stop4h 31mAmerican Airlines
Deal found 3/25$302
This Southwest deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/303:40 pmDSM - SAT
1 stop7h 15mSouthwest
Wed 5/71:05 pmSAT - DSM
2 stops9h 00mSouthwest
Deal found 3/25$308
This United Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2311:38 amDSM - SAT
2 stops10h 03mUnited Airlines
Wed 4/309:35 amSAT - DSM
1 stop4h 56mUnited Airlines
Deal found 3/25$331

Cheapflights Fare Finder

Customize your flight search to find flights from Des Moines to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 26, 2025.
Use the filters below to find and compare flights from Des Moines to San Antonio that are best for you.

Fly from

Des Moines

Fly to

San Antonio

Route

Depart

Return

Price

Des MoinesSan Antonio

DSM - SAT

DSMSAT

Des Moines

Sat 4/26

6:30 am-12:46 pm

1 stop6h 16m

San Antonio

Tue 4/29

8:15 am-1:24 pm

1 stop5h 09m

$297

Des MoinesSan Antonio

DSM - SAT

DSMSAT

Des Moines

Mon 4/28

3:25 pm-9:14 am

1 stop17h 49m

San Antonio

Sat 5/3

6:31 pm-2:54 pm

2 stops20h 23m

$298

Des MoinesSan Antonio

DSM - SAT

DSMSAT

Des Moines

Sat 4/26

5:43 am-1:38 pm

2 stops7h 55m

San Antonio

Wed 4/30

6:22 pm-10:53 pm

1 stop4h 31m

$302

Des MoinesSan Antonio

DSM - SAT

DSMSAT

Des Moines

Wed 4/30

3:40 pm-10:55 pm

1 stop7h 15m

San Antonio

Wed 5/7

1:05 pm-10:05 pm

2 stops9h 00m

$308

Des MoinesSan Antonio

DSM - SAT

DSMSAT

Des Moines

Wed 4/23

11:38 am-9:41 pm

2 stops10h 03m

San Antonio

Wed 4/30

9:35 am-2:31 pm

1 stop4h 56m

$331

Des MoinesSan Antonio

DSM - SAT

DSMSAT

Des Moines

Fri 4/4

8:17 pm-1:17 pm

1 stop17h 00m

$126

Des MoinesSan Antonio

DSM - SAT

DSMSAT

Des Moines

Fri 4/18

3:40 pm-12:05 am

2 stops8h 25m

$174

Des MoinesSan Antonio

DSM - SAT

DSMSAT

Des Moines

Mon 5/12

6:45 pm-9:06 pm

2 stops26h 21m

$218

Des MoinesSan Antonio

DSM - SAT

DSMSAT

Des Moines

Fri 4/18

6:30 am-8:01 pm

3 stops37h 31m

$222

Des MoinesSan Antonio

DSM - SAT

DSMSAT

Des Moines

Tue 4/1

5:06 am-11:49 am

1 stop6h 43m

$234

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/25

Compare providers for flights from Des Moines to San Antonio

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to San Antonio in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
MytripPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-San Antonio flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-San Antonio flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-San Antonio flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-San Antonio flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-San Antonio flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to San Antonio

Have a flexible travel schedule? Discover the best time to fly to San Antonio from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to San Antonio

How far ahead should I book a flight from Des Moines to San Antonio?

Use this chart to determine the optimal time to book a round-trip flight from Des Moines to San Antonio. Price data was last updated on March 21, 2025.

The price you pay for your flight from Des Moines to San Antonio may vary depending on when you book. For the best chance of a lower fare, look to book 27 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Des Moines to San Antonio?

Currently, August is the cheapest month in which you can book a flight from Des Moines to San Antonio (average of $295). Flying from Des Moines to San Antonio in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to SAT?

Find hourly flight availability from Des Moines to San Antonio. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 26, 2025.

One of the essential ways to save on airfare from Des Moines to San Antonio is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 26% on airfare.

What is the cheapest day to fly from Des Moines to San Antonio?

Use this chart to determine the cheapest time to fly round-trip from Des Moines to San Antonio. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Des Moines to San Antonio flight should consider departing on Monday evenings when fares are most often at their lowest. Monday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Rainfall in San Antonio by month

Plan your trip to San Antonio by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in San Antonio ranges from 1.6 - 3.7 inches per month. May is typically the wettest month, when rainfall can reach 3.7 in. December is typically the driest time to visit San Antonio when rainfall is around 1.6 in.

Temperature in San Antonio by month

Plan your trip to San Antonio by taking into account the average temperature totals by month.

If weather is an important factor for your trip to San Antonio, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

Reviews of airlines servicing San Antonio

Get insights into the airlines that provide service to San Antonio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Antonio. Reviews last updated March 26, 2025.
Get a feel of what it's like to fly with Southwest, Delta and United Airlines from Des Moines to San Antonio by reading reviews from past customers. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,273 reviews

Comfort

8.1

Food

7.1

Overall

8.1

Entertainment

7.6

Crew

8.6

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Southwest
8.1
Very good
4,273 reviews
Southwest
8.1
Very good
4,273 reviews

Comfort

8.1

Food

7.1

Overall

8.1

Entertainment

7.6

Crew

8.6

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Delta
8.0
Very good
7,891 reviews
Southwest
8.1
Very good
4,273 reviews

Comfort

8.1

Food

7.1

Overall

8.1

Entertainment

7.6

Crew

8.6

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
United Airlines
7.4
Good
8,608 reviews
Southwest
8.1
Very good
4,273 reviews

Comfort

8.1

Food

7.1

Overall

8.1

Entertainment

7.6

Crew

8.6

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,273 reviews

Comfort

8.1

Food

7.1

Overall

8.1

Entertainment

7.6

Crew

8.6

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Frontier
6.0
Okay
3,272 reviews
Southwest
8.1
Very good
4,273 reviews

Comfort

8.1

Food

7.1

Overall

8.1

Entertainment

7.6

Crew

8.6

Boarding

8.2

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to San Antonio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Des Moines to San Antonio round-trip?

    Currently priced at $297, Delta will fly you from Des Moines to San Antonio and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from American Airlines and Southwest - these airlines can fly you to your destination from $302 and $308, respectively. These flights start at 23% lower than the current average price 3 months from now.

  • What are the cheapest airlines to fly from Des Moines to San Antonio one-way?

    The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $126. However, be on the lookout for offers from Southwest and United Airlines, as they are both options that can get you from Des Moines to San Antonio for a low price.

  • Can I find deals for flights from Des Moines to San Antonio that include hotel bookings?

    Yes. In addition to deals on Des Moines to San Antonio flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to San Antonio?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to San Antonio.

  • Can I find deals for business class flights from Des Moines to San Antonio?

    Yes. Cheapflights offers flight deals from Des Moines to San Antonio by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to San Antonio?

    Currently, August is the cheapest month in which you can book a flight from Des Moines to San Antonio (average of $295). Flying from Des Moines to San Antonio in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
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Top 5 airlines flying from Des Moines to San Antonio

Discover the top 5 airlines that operate flights from Des Moines to San Antonio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 26, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$111Average$201FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$285Average$396FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$286Average$450FlexibilityNo cancel feeOn-time69%
DeltaCheapest$292Average$366FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$331Average$396FlexibilityNo cancel feeOn-time63%
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