What are the cheapest airlines to fly from South Carolina to Portland one-way?

The cheapest airline one-way is Spirit Airlines, with whom users have recently found tickets for as low as $116. However, be on the lookout for offers from Frontier and American Airlines, as they are both options that can get you from South Carolina to Portland for a low price.

What are the most popular routes from South Carolina to Portland?

When deciding which route to take from South Carolina to Portland consider Charlotte Douglas - Portland, Columbia Metropolitan - Portland or Greenville - Portland as they are the most popular.

What are the most popular airlines that fly from South Carolina to Portland?

The most popular airlines flying from South Carolina to Portland are American Airlines, Alaska Airlines and Delta. Something to consider prior to booking your flight.

How far in advance should I book a flight from South Carolina to Portland?

Find a great deal and save up to 119% by booking at least 19 days prior to your desired departure date, rather than waiting until the week of travel. According to our data, there are a number of flights available from South Carolina to Portland within the next two weeks, with the cheapest ticket starting at $385.

What is the cheapest month to fly from South Carolina to Portland?

Our data shows that February tends to be the cheapest month to fly to Portland from South Carolina. Users have commonly found prices around $524 for the month, but tickets can be as low as $396. Due to multiple factors, prepare for potentially higher prices in December.

What airport do you fly into for flights to Portland from South Carolina?

For a flight from South Carolina to Portland, you will be flying into Portland. Portland (PDX) is just 6.0 mi from the center of the city.

Can I find deals for flights from South Carolina to Portland that include hotel bookings?

Yes. In addition to deals on South Carolina to Portland flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from South Carolina to Portland?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Portland.

Can I find deals for business class flights from South Carolina to Portland?

Yes. Cheapflights offers flight deals from South Carolina to Portland by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$116+ Flights from South Carolina to Portland

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from South Carolina to Portland with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from South Carolina to Portland

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars
Round-trip from	$262 (Delta)
One-way from	$116 (Booking.com)
Popular in	December
Cheapest in	February
Average price	$562

Provider with most accurate pricing for Myrtle Beach Intl-Portland flight deals.

Search Deals

Provider most trusted by Cheapflights users for Myrtle Beach Intl-Portland flights.

Search Deals

From South Carolina to Portland

Search Deals

One-way flight from South Carolina to Portland

Search Deals

Highest demand for flights based on searches. 18% potential increase in price ($122 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 8% potential price decrease ($40 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in March 2025

Search Deals

Find flight deals from South Carolina to Portland

Cheapest flights from South Carolina to Portland
Explore the most affordable flight options available from South Carolina to Portland. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 31, 2025.

Sat 6/1412:15 pmAGS - PDX

1 stop9h 46mDelta

Tue 6/177:59 pmPDX - AGS

2 stops10h 21mDelta

Deal found 3/30

$262

Wed 4/234:20 pmCLT - PDX

3 stops28h 45mSpirit Airlines

Wed 4/302:32 pmPDX - CLT

1 stop12h 13mSpirit Airlines

Deal found 3/30

$284

Thu 4/1710:20 pmCLT - PDX

1 stop29h 17mFrontier

Mon 4/216:40 amPDX - CLT

1 stop9h 17mFrontier

Deal found 3/31

$288

Tue 4/156:58 amCLT - PDX

1 stop9h 39mMultiple Airlines

Tue 4/226:20 amPDX - CLT

1 stop6h 42mMultiple Airlines

Deal found 3/30

$294

Sat 10/184:07 pmCHS - PDX

1 stop7h 48mAmerican Airlines

Tue 10/218:01 amPDX - CHS

1 stop6h 49mAmerican Airlines

Deal found 3/30

$315

Thu 5/84:21 pmAGS - PDX

2 stops10h 38mAmerican Airlines

Tue 5/139:38 pmPDX - AGS

1 stop10h 03mAmerican Airlines

Deal found 3/31

$318

Sat 10/182:25 pmCHS - PDX

2 stops12h 26mDelta

Tue 10/217:00 amPDX - CHS

1 stop10h 54mDelta

Deal found 3/29

$320

Tue 4/2212:08 pmMYR - PDX

3 stops28h 29mSpirit Airlines

Fri 4/257:01 pmPDX - MYR

2 stops13h 54mSpirit Airlines

Deal found 3/30

$323

Fri 6/201:23 pmCLT - PDX

1 stop12h 23mSun Country Air

Mon 6/2311:59 pmPDX - CLT

1 stop8h 56mSun Country Air

Deal found 3/30

$325

Tue 6/101:32 pmCAE - PDX

1 stop8h 29mDelta

Sun 6/159:50 pmPDX - CAE

1 stop8h 26mDelta

Deal found 3/30

$329

Thu 4/244:16 pmGSP - PDX

1 stop8h 17mAmerican Airlines

Tue 4/2911:52 pmPDX - GSP

1 stop8h 22mAmerican Airlines

Deal found 3/31

$332

Mon 5/57:00 amCHS - PDX

1 stop9h 01mUnited Airlines

Fri 5/911:59 pmPDX - CHS

1 stop7h 32mUnited Airlines

Deal found 3/30

$337

Best flights from South Carolina to Portland
Discover carefully curated flight deals from South Carolina to Portland that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 31, 2025.

Sat 6/1412:15 pmAGS - PDX

1 stop9h 46mDelta

Tue 6/177:59 pmPDX - AGS

2 stops10h 21mDelta

Deal found 3/30

$262

Wed 4/234:20 pmCLT - PDX

3 stops28h 45mSpirit Airlines

Wed 4/302:32 pmPDX - CLT

1 stop12h 13mSpirit Airlines

Deal found 3/30

$284

Thu 4/1710:20 pmCLT - PDX

1 stop29h 17mFrontier

Mon 4/216:40 amPDX - CLT

1 stop9h 17mFrontier

Deal found 3/31

$288

Tue 4/156:58 amCLT - PDX

1 stop9h 39mMultiple Airlines

Tue 4/226:20 amPDX - CLT

1 stop6h 42mMultiple Airlines

Deal found 3/30

$294

Fri 5/24:58 pmCHS - PDX

1 stop9h 04mAmerican Airlines

Thu 5/810:24 pmPDX - CHS

1 stop8h 28mAmerican Airlines

Deal found 3/31

$317

Fri 6/201:23 pmCLT - PDX

1 stop12h 23mSun Country Air

Mon 6/2311:59 pmPDX - CLT

1 stop8h 56mSun Country Air

Deal found 3/31

$325

Mon 5/57:00 amCHS - PDX

1 stop9h 01mUnited Airlines

Fri 5/911:59 pmPDX - CHS

1 stop7h 32mUnited Airlines

Deal found 3/30

$337

Wed 6/43:40 pmCLT - PDX

2 stops10h 30mSouthwest

Wed 6/115:40 amPDX - CLT

2 stops8h 10mSouthwest

Deal found 3/29

$371

Thu 5/84:21 pmAGS - PDX

2 stops10h 38mAmerican Airlines

Tue 5/139:38 pmPDX - AGS

1 stop10h 03mAmerican Airlines

Deal found 3/31

$318

Tue 4/2212:08 pmMYR - PDX

3 stops28h 29mSpirit Airlines

Fri 4/257:01 pmPDX - MYR

2 stops13h 54mSpirit Airlines

Deal found 3/30

$323

Fri 7/188:20 amCHS - PDX

1 stop7h 29mDelta

Thu 8/79:45 pmPDX - CHS

1 stop8h 58mDelta

Deal found 3/30

$327

Thu 4/244:36 pmGSP - PDX

1 stop9h 38mUnited Airlines

Tue 4/2911:30 pmPDX - GSP

1 stop7h 25mUnited Airlines

Deal found 3/31

$351

Last-minute flights from South Carolina to Portland
Discover last-minute flight deals from South Carolina to Portland. Data last updated March 31, 2025 and is based on user searches.

Sat 4/57:47 pmCLT - PDX

1 stop7h 51mFrontier

Sun 4/66:40 amPDX - CLT

1 stop11h 50mFrontier

Deal found 3/31

$338

Sat 4/511:13 amAGS - PDX

2 stops11h 41mAmerican Airlines

Tue 4/1510:00 pmPDX - AGS

1 stop9h 38mAmerican Airlines

Deal found 3/30

$522

Sat 4/55:00 pmAGS - PDX

1 stop7h 48mDelta

Tue 4/156:00 amPDX - AGS

1 stop6h 59mDelta

Deal found 3/30

$567

Mon 4/76:07 pmCLT - PDX

2 stops19h 13mSpirit Airlines

Tue 4/157:01 pmPDX - CLT

2 stops11h 35mSpirit Airlines

Deal found 3/30

$304

Mon 4/77:54 pmCLT - PDX

1 stop7h 43mMultiple Airlines

Tue 4/157:01 pmPDX - CLT

2 stops11h 35mMultiple Airlines

Deal found 3/30

$306

Tue 4/86:00 pmCLT - PDX

Nonstop5h 35mAmerican Airlines

Tue 4/1510:00 pmPDX - CLT

Nonstop5h 02mAmerican Airlines

Deal found 3/31

$514

Tue 4/810:43 amCLT - PDX

1 stop7h 32mUnited Airlines

Mon 4/1412:54 pmPDX - CLT

1 stop6h 45mUnited Airlines

Deal found 3/30

$529

Tue 4/83:25 pmCLT - PDX

1 stop8h 30mSouthwest

Tue 4/155:20 amPDX - CLT

1 stop9h 25mSouthwest

Deal found 3/31

$534

Tue 4/83:06 pmCLT - PDX

1 stop10h 32mDelta

Sun 4/1312:59 amPDX - CLT

1 stop8h 30mDelta

Deal found 3/30

$554

Tue 4/85:25 pmGSP - PDX

1 stop8h 11mUnited Airlines

Mon 4/1411:30 pmPDX - GSP

1 stop7h 25mUnited Airlines

Deal found 3/31

$567

Tue 4/83:40 pmGSP - PDX

2 stops10h 30mSouthwest

Mon 4/145:45 amPDX - GSP

2 stops9h 50mSouthwest

Deal found 3/31

$577

Tue 4/85:20 pmGSP - PDX

1 stop7h 28mDelta

Mon 4/1412:59 amPDX - GSP

2 stops10h 36mDelta

Deal found 3/31

$582

One-way flights from South Carolina to Portland
Search for one-way flight options from South Carolina to Portland. Find affordable one-way fares based on user searches. Data last updated March 31, 2025.

Thu 5/16:30 pmCLT - PDX

2 stops18h 27mSpirit Airlines

Deal found 3/30

$116

Thu 5/15:06 pmCLT - PDX

1 stop10h 32mFrontier

Deal found 3/31

$119

Sat 4/194:51 pmCAE - PDX

1 stop8h 56mAmerican Airlines

Deal found 3/30

$125

Sat 4/193:00 pmCAE - PDX

2 stops10h 35mDelta

Deal found 3/30

$130

Tue 4/292:46 pmCHS - PDX

2 stops12h 10mDelta

Deal found 3/30

$133

Fri 5/22:55 pmCHS - PDX

1 stop9h 10mSouthwest

Deal found 3/30

$138

Fri 5/210:32 amCHS - PDX

2 stops30h 05mSpirit Airlines

Deal found 3/30

$153

Fri 7/186:15 pmCLT - PDX

1 stop7h 31mSun Country Air

Deal found 3/30

$153

Wed 4/306:00 amCHS - PDX

1 stop10h 12mJetBlue

Deal found 3/30

$157

Thu 5/112:00 pmSAV - PDX

1 stop26h 19mSun Country Air

Deal found 3/30

$158

Wed 4/305:35 pmCLT - PDX

1 stop9h 09mDelta

Deal found 3/31

$172

Tue 9/94:28 pmGSP - PDX

1 stop6h 58mAmerican Airlines

Deal found 3/30

$176

Cheapflights Fare Finder

Use the filters below to find and compare flights from South Carolina to Portland that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

AugustaPortland

AGS - PDX

AGSPDX

Augusta Bush Field

Sat 6/14

12:15 pm-7:01 pm

1 stop9h 46m

Portland

Tue 6/17

7:59 pm-9:20 am

2 stops10h 21m

$262

CharlottePortland

CLT - PDX

CLTPDX

Charlotte Douglas

Wed 4/23

4:20 pm-6:05 pm

3 stops28h 45m

Portland

Wed 4/30

2:32 pm-5:45 am

1 stop12h 13m

$284

CharlottePortland

CLT - PDX

CLTPDX

Charlotte Douglas

Thu 4/17

10:20 pm-12:37 am

1 stop29h 17m

Portland

Mon 4/21

6:40 am-6:57 pm

1 stop9h 17m

$288

CharlottePortland

CLT - PDX

CLTPDX

Charlotte Douglas

Tue 4/15

6:58 am-1:37 pm

1 stop9h 39m

Portland

Tue 4/22

6:20 am-4:02 pm

1 stop6h 42m

$294

CharlottePortland

CLT - PDX

CLTPDX

Charlotte Douglas

Fri 7/18

6:15 pm-10:46 pm

1 stop7h 31m

Portland

Thu 8/7

11:59 pm-5:19 pm

1 stop14h 20m

$315

CharlestonPortland

CHS - PDX

CHSPDX

Charleston

Fri 5/2

4:58 pm-11:02 pm

1 stop9h 04m

Portland

Thu 5/8

10:24 pm-9:52 am

1 stop8h 28m

$317

AugustaPortland

AGS - PDX

AGSPDX

Augusta Bush Field

Thu 5/8

4:21 pm-11:59 pm

2 stops10h 38m

Portland

Tue 5/13

9:38 pm-10:41 am

1 stop10h 03m

$318

Myrtle BeachPortland

MYR - PDX

MYRPDX

Myrtle Beach Intl

Tue 4/22

12:08 pm-1:37 pm

3 stops28h 29m

Portland

Fri 4/25

7:01 pm-11:55 am

2 stops13h 54m

$323

CharlestonPortland

CHS - PDX

CHSPDX

Charleston

Fri 7/18

8:20 am-12:49 pm

1 stop7h 29m

Portland

Thu 8/7

9:45 pm-9:43 am

1 stop8h 58m

$327

ColumbiaPortland

CAE - PDX

CAEPDX

Columbia Metropolitan

Tue 6/10

1:32 pm-7:01 pm

1 stop8h 29m

Portland

Sun 6/15

9:50 pm-9:16 am

1 stop8h 26m

$329

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/30

Showing 1-10 of 60 results

...

Best time to book a flight from South Carolina to Portland

Have a flexible travel schedule? Discover the best time to fly to Portland from South Carolina with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Portland

What is the cheapest month to book a flight from South Carolina to Portland?

Currently, November is the cheapest month in which you can book a flight from South Carolina to Portland (average of $277). Flying from South Carolina to Portland in March is currently the most expensive (average of $369). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to PDX?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Portland as you normally would.

Rainfall in Portland by month

In terms of precipitation, rainfall in Portland ranges from 0.7 - 5.6 inches per month. November is typically the wettest month, when rainfall can reach 5.6 in. July is typically the driest time to visit Portland when rainfall is around 0.7 in.

Temperature in Portland by month

If weather is an important factor for your trip to Portland, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 69.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 41.0 F).

Reviews of airlines servicing Portland

Read reviews from past customers who have flown Alaska Airlines, Southwest and Delta from South Carolina to Portland. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Alaska Airlines

8.0

Very good

9,818 reviews

Reviews

1 / 20

10.0

Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

Alaska Airlines

8.0

Very good

9,818 reviews

Alaska Airlines

8.0

Very good

9,818 reviews

Reviews

1 / 20

10.0

Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

Southwest

8.0

Very good

4,276 reviews

Alaska Airlines

8.0

Very good

9,818 reviews

Reviews

1 / 20

10.0

Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

Delta

8.0

Very good

7,899 reviews

Alaska Airlines

8.0

Very good

9,818 reviews

Reviews

1 / 20

10.0

Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

United Airlines

7.4

Good

8,614 reviews

Alaska Airlines

8.0

Very good

9,818 reviews

Reviews

1 / 20

10.0

Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

JetBlue

7.3

Good

2,924 reviews

Alaska Airlines

8.0

Very good

9,818 reviews

Reviews

1 / 20

10.0

Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

Related info for your journey

What airport do you fly into for flights to Portland from South Carolina?
For a flight from South Carolina to Portland, you will be flying into Portland. Portland (PDX) is just 6.0 mi from the center of the city.
What are the cheapest airlines to fly from South Carolina to Portland one-way?
The cheapest airline one-way is Spirit Airlines, with whom users have recently found tickets for as low as $116. However, be on the lookout for offers from Frontier and American Airlines, as they are both options that can get you from South Carolina to Portland for a low price.
What are the most popular routes from South Carolina to Portland?
When deciding which route to take from South Carolina to Portland consider Charlotte Douglas - Portland, Columbia Metropolitan - Portland or Greenville - Portland as they are the most popular.
Can I find deals for flights from South Carolina to Portland that include hotel bookings?
Yes. In addition to deals on South Carolina to Portland flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from South Carolina to Portland?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Portland.
Can I find deals for business class flights from South Carolina to Portland?
Yes. Cheapflights offers flight deals from South Carolina to Portland by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from South Carolina to Portland?
Currently, November is the cheapest month in which you can book a flight from South Carolina to Portland (average of $277). Flying from South Carolina to Portland in March is currently the most expensive (average of $369). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Lincoln City

Beaverton

Seaside

Clackamas

Vancouver

McMinnville

Lake Oswego

Hillsboro

Gresham

Long Beach

Cannon Beach

Tigard

Astoria

Hood River

Woodburn

Depoe Bay

Pacific City

Stevenson

Troutdale

Longview

Browse thousands of different options on Cheapflights for your next trip

Top 6 airlines flying from South Carolina to Portland

Airline	Cheapest	Average	Flexibility	On-time
Spirit Airlines	Cheapest$121	Average$254	FlexibilityNo cancel fee	On-time65%
United Airlines	Cheapest$254	Average$484	FlexibilityNo cancel fee	On-time69%
Southwest	Cheapest$289	Average$488	FlexibilityNo cancel fee	On-time63%
Delta	Cheapest$296	Average$514	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$296	Average$459	FlexibilityNo cancel fee	On-time71%
Alaska Airlines	Cheapest$297	Average$501	FlexibilityNo cancel fee	On-time75%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$116+ Cheap flights from South Carolina to Portland (PDX)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/1. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from South Carolina to Portland with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from South Carolina to Portland

Keep the following information in mind while searching for South Carolina to Portland flight deals. Data was last updated March 31, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from South Carolina to Portland

Cheapest flights from South Carolina to PortlandExplore the most affordable flight options available from South Carolina to Portland. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 31, 2025.

Explore the most affordable flight options available from South Carolina to Portland. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 31, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from South Carolina to Portland that are best for you.

Best time to book a flight from South Carolina to Portland

Have a flexible travel schedule? Discover the best time to fly to Portland from South Carolina with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Portland

What is the cheapest month to book a flight from South Carolina to Portland?

What is the cheapest time of day to fly from SC to PDX?

Find hourly flight availability from South Carolina to Portland. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 31, 2025.

Rainfall in Portland by month

Plan your trip to Portland by taking into account the average rainfall totals by month.

Temperature in Portland by month

Plan your trip to Portland by taking into account the average temperature totals by month.

Reviews of airlines servicing Portland

Read reviews from past customers who have flown Alaska Airlines, Southwest and Delta from South Carolina to Portland. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Portland. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Portland from South Carolina?

What are the cheapest airlines to fly from South Carolina to Portland one-way?

What are the most popular routes from South Carolina to Portland?

Can I find deals for flights from South Carolina to Portland that include hotel bookings?

How can I find direct flights from South Carolina to Portland?

Can I find deals for business class flights from South Carolina to Portland?

What is the cheapest month to book a flight from South Carolina to Portland?

Traveling to a place near South Carolina?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to Portland

See prices for flight routes from nearby airports that may be better suited for you.

Top 6 airlines flying from South Carolina to Portland

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from South Carolina to Portland
Explore the most affordable flight options available from South Carolina to Portland. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 31, 2025.