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$132+ Cheap flights from the United States to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/25. Fares are subject to change and may not be available on all flights or dates of travel.
LAX — PTY
Apr 5 — Apr 121
Sat 4/5
Sat 4/12
1 adult, Economy
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Cheap flight deals from USA to Panama

Keep the following information in mind while searching for USA to Panama flight deals. Data was last updated March 31, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$279
(Copa Airlines)

One-way from

$132
(Avianca Connect)

Popular in

December

Cheapest in

September

Average price

$635

Good round-trip deal

$299 or less

Good one-way deal

$159 or less
Provider with most accurate pricing for New York (NYC)-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for New York (NYC)-Panama City Tocumen Intl flights.
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From USA to Panama
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One-way flight from USA to Panama
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Highest demand for flights based on searches. 7% potential increase in price ($44 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($17 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Price to beat on a round-trip flight from USA to Panama.
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Price to beat on a one-way flight from USA to Panama.
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Find flight deals from USA to Panama

Cheapest flights from USA to Panama
Explore the most affordable flight options available from USA to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 31, 2025.

This Copa Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/146:20 amMIA - PTY
Nonstop3h 10mCopa Airlines
Wed 5/219:33 pmPTY - MIA
Nonstop3h 05mCopa Airlines
Deal found 3/30$279
This Avianca deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/58:15 amMIA - PTY
1 stop7h 25mAvianca
Sat 4/53:20 amPTY - MIA
1 stop8h 10mAvianca
Deal found 3/29$281
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/258:10 amMIA - PTY
1 stop12h 20mDelta
Sun 5/47:30 amPTY - MIA
1 stop9h 57mDelta
Deal found 3/30$293
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/110:14 amMIA - PTY
Nonstop3h 05mAmerican Airlines
Sat 6/73:20 pmPTY - MIA
Nonstop3h 05mAmerican Airlines
Deal found 3/30$320
This Avianca Connect deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/55:45 amATL - PTY
2 stops19h 25mMultiple Airlines
Sat 5/1010:05 pmPTY - ATL
2 stops19h 29mMultiple Airlines
Deal found 3/30$343
This United Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/97:00 amMIA - PTY
1 stop12h 37mUnited Airlines
Sat 7/267:55 amPTY - MIA
1 stop11h 50mUnited Airlines
Deal found 3/29$353
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/16:24 amMIA - PTY
Nonstop3h 06mMultiple Airlines
Wed 8/63:20 amPTY - MIA
1 stop8h 10mMultiple Airlines
Deal found 3/31$368
This Trip.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/44:25 pmMCO - PTY
1 stop8h 45mAvianca
Tue 4/83:20 amPTY - MCO
1 stop9h 15mAvianca
Deal found 3/30$400
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/259:13 amMCO - PTY
1 stop9h 03mMultiple Airlines
Fri 5/99:34 amPTY - MCO
1 stop6h 21mMultiple Airlines
Deal found 3/30$402
This Avianca Connect deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/39:55 amLGA - PTY
2 stops15h 15mMultiple Airlines
Mon 6/910:05 pmPTY - LGA
2 stops18h 25mMultiple Airlines
Deal found 3/31$415
This Expedia deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/67:00 amIAD - PTY
1 stop10h 30mAvianca
Wed 4/93:20 amPTY - IAD
1 stop25h 15mAvianca
Deal found 3/31$435
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/71:00 pmJFK - PTY
1 stop8h 37mMultiple Airlines
Tue 5/209:33 pmPTY - JFK
1 stop13h 26mMultiple Airlines
Deal found 3/31$437

Cheapflights Fare Finder

Customize your flight search to find flights from USA to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2025.
Use the filters below to find and compare flights from the United States to Panama that are best for you.

Fly from

USA

Fly to

Panama

Route

Depart

Return

Price

MiamiPanama City

MIA - PTY

MIAPTY

Miami

Wed 5/14

6:20 am-8:30 am

Nonstop3h 10m

Panama City Tocumen Intl

Wed 5/21

9:33 pm-1:38 am

Nonstop3h 05m

$279

MiamiPanama City

MIA - PTY

MIAPTY

Miami

Sat 5/24

8:15 am-7:15 pm

1 stop12h 00m

Panama City Tocumen Intl

Sat 5/24

3:20 am-12:30 pm

1 stop8h 10m

$281

MiamiPanama City

MIA - PTY

MIAPTY

Miami

Fri 4/25

6:00 am-12:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Sat 4/26

2:20 pm-9:20 am

1 stop18h 00m

$293

MiamiPanama City

MIA - PTY

MIAPTY

Miami

Sun 6/1

10:14 am-12:19 pm

Nonstop3h 05m

Panama City Tocumen Intl

Sat 6/7

3:20 pm-7:25 pm

Nonstop3h 05m

$320

AtlantaPanama City

ATL - PTY

ATLPTY

Atlanta Hartsfield-Jackson

Mon 5/5

5:45 am-12:10 am

2 stops19h 25m

Panama City Tocumen Intl

Sat 5/10

10:05 pm-6:34 pm

2 stops19h 29m

$343

MiamiPanama City

MIA - PTY

MIAPTY

Miami

Wed 7/9

7:00 am-6:37 pm

1 stop12h 37m

Panama City Tocumen Intl

Sat 7/26

7:55 am-8:45 pm

1 stop11h 50m

$353

MiamiPanama City

MIA - PTY

MIAPTY

Miami

Fri 8/1

2:20 pm-4:26 pm

Nonstop3h 06m

Panama City Tocumen Intl

Thu 8/7

10:05 pm-9:50 am

1 stop10h 45m

$368

OrlandoPanama City

MCO - PTY

MCOPTY

Orlando

Wed 6/4

4:25 pm-12:45 am

1 stop9h 20m

Panama City Tocumen Intl

Fri 6/6

3:40 pm-11:00 am

1 stop18h 20m

$400

OrlandoPanama City

MCO - PTY

MCOPTY

Orlando

Fri 4/25

9:13 am-5:16 pm

1 stop9h 03m

Panama City Tocumen Intl

Fri 5/9

9:34 am-4:55 pm

1 stop6h 21m

$402

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Tue 6/3

9:55 am-12:10 am

2 stops15h 15m

Panama City Tocumen Intl

Mon 6/9

10:05 pm-5:30 pm

2 stops18h 25m

$415

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/30

Showing 1-10 of 60 results
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Best time to book a flight from USA to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from USA with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from the United States to Panama

What is the cheapest month to book a flight from USA to Panama?

Currently, October is the cheapest month in which you can book a flight from USA to Panama (average of $478). Flying from USA to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from US to PA?

Find hourly flight availability from USA to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 31, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from USA to Panama as you normally would.

Rainfall in Panama by month

Plan your trip to Panama by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama when rainfall is around 0.4 in.

Temperature in Panama by month

Plan your trip to Panama by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated March 31, 2025.
Read through reviews of airlines operating flights from USA to Panama, such as Delta, Copa Airlines and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,899 reviews

Crew

8.5

Entertainment

7.9

Food

7.3

Boarding

8.2

Overall

8.0

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,899 reviews
Delta
8.0
Very good
7,899 reviews

Crew

8.5

Entertainment

7.9

Food

7.3

Boarding

8.2

Overall

8.0

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.6
Good
1,400 reviews
Delta
8.0
Very good
7,899 reviews

Crew

8.5

Entertainment

7.9

Food

7.3

Boarding

8.2

Overall

8.0

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,614 reviews
Delta
8.0
Very good
7,899 reviews

Crew

8.5

Entertainment

7.9

Food

7.3

Boarding

8.2

Overall

8.0

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Turkish Airlines
7.3
Good
3,748 reviews
Delta
8.0
Very good
7,899 reviews

Crew

8.5

Entertainment

7.9

Food

7.3

Boarding

8.2

Overall

8.0

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,899 reviews

Crew

8.5

Entertainment

7.9

Food

7.3

Boarding

8.2

Overall

8.0

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from USA to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this USA to Panama flight route?

    Within the past month, 184 users have taken a look at flights from United States to Panama.

  • What are the cheapest airlines to fly from USA to Panama one-way?

    One-way options have recently been found by users for as low as $135 on American Airlines. Other airlines that offer cheap prices include Delta from $139 and Avianca from $140 one-way.

  • Can I find deals for flights from USA to Panama that include hotel bookings?

    Yes. In addition to deals on USA to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from USA to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from USA to Panama.

  • Can I find deals for business class flights from USA to Panama?

    Yes. Cheapflights offers flight deals from USA to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from USA to Panama?

    Currently, October is the cheapest month in which you can book a flight from USA to Panama (average of $478). Flying from USA to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for USA to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from USA to Panama

Discover the top 5 airlines that operate flights from USA to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$191Average$653FlexibilityNo cancel feeOn-time70%
AviancaCheapest$207Average$505FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$285Average$664FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$292Average$583FlexibilityNo cancel feeOn-time71%
DeltaCheapest$304Average$623FlexibilityNo cancel feeOn-timeN/A
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