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$68+ Cheap flights from the United States to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/14. Fares are subject to change and may not be available on all flights or dates of travel.
LAX — PTY
Apr 27 — May 41
Sun 4/27
Sun 5/4
1 adult, Economy
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Cheap flight deals from USA to Panama

Keep the following information in mind while searching for USA to Panama flight deals. Data was last updated April 22, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$266
(Copa Airlines)

One-way from

$68
(American Airlines)

Popular in

December

Cheapest in

October

Average price

$686

Good round-trip deal

$285 or less

Good one-way deal

$145 or less
Provider with most accurate pricing for New York (NYC)-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for New York (NYC)-Panama City Tocumen Intl flights.
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From USA to Panama
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One-way flight from USA to Panama
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Highest demand for flights based on searches. 6% potential increase in price ($38 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($17 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Price to beat on a round-trip flight from USA to Panama.
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Price to beat on a one-way flight from USA to Panama.
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Find flight deals from USA to Panama

Cheapest flights from USA to Panama
Explore the most affordable flight options available from USA to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2025.

This Copa Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/215:19 pmMIA - PTY
Nonstop3h 10mCopa Airlines
Sun 6/89:33 pmPTY - MIA
Nonstop3h 11mCopa Airlines
Deal found 4/22$266
This Viajes Éxito deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Viajes Éxito is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/511:20 amMIA - PTY
1 stop10h 50mAvianca
Wed 6/115:25 pmPTY - MIA
1 stop15h 25mAvianca
Deal found 4/22$267
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/136:20 amMIA - PTY
Nonstop3h 10mMultiple Airlines
Mon 6/1610:05 pmPTY - MIA
1 stop10h 45mMultiple Airlines
Deal found 4/22$334
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/1710:30 amMIA - PTY
Nonstop3h 30mAmerican Airlines
Mon 6/231:50 pmPTY - MIA
Nonstop3h 05mAmerican Airlines
Deal found 4/22$339
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/117:00 amMIA - PTY
1 stop12h 37mUnited Airlines
Wed 10/1510:00 amPTY - MIA
1 stop10h 12mUnited Airlines
Deal found 4/22$353
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/88:59 pmJFK - PTY
2 stops16h 20mAmerican Airlines
Mon 5/121:20 pmPTY - JFK
2 stops17h 32mAmerican Airlines
Deal found 4/22$370
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/17:50 pmLGA - PTY
2 stops17h 29mAmerican Airlines
Mon 6/91:50 pmPTY - LGA
1 stop8h 09mAmerican Airlines
Deal found 4/22$370
This Avianca Connect deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/306:00 amATL - PTY
2 stops16h 10mMultiple Airlines
Sat 5/1010:05 pmPTY - ATL
2 stops19h 35mMultiple Airlines
Deal found 4/21$370
This Avianca Connect deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/85:55 amLGA - PTY
2 stops16h 15mMultiple Airlines
Tue 10/283:19 amPTY - LGA
2 stops17h 46mMultiple Airlines
Deal found 4/21$391
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/209:45 amATL - PTY
Nonstop4h 03mDelta
Fri 5/232:13 pmPTY - ATL
Nonstop4h 19mDelta
Deal found 4/22$397
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/612:59 pmJFK - PTY
1 stop8h 38mMultiple Airlines
Mon 6/99:33 pmPTY - JFK
1 stop13h 25mMultiple Airlines
Deal found 4/22$407
This Copa Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/264:10 pmATL - PTY
Nonstop4h 23mCopa Airlines
Thu 7/109:25 amPTY - ATL
Nonstop4h 21mCopa Airlines
Deal found 4/22$407

Cheapflights Fare Finder

Customize your flight search to find flights from USA to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 22, 2025.
Use the filters below to find and compare flights from the United States to Panama that are best for you.

Fly from

USA

Fly to

Panama

Route

Depart

Return

Price

MiamiPanama City

MIA - PTY

MIAPTY

Miami

Wed 5/21

2:16 pm-4:26 pm

Nonstop3h 10m

Panama City Tocumen Intl

Fri 5/23

3:44 pm-7:59 pm

Nonstop3h 15m

$266

MiamiPanama City

MIA - PTY

MIAPTY

Miami

Thu 6/5

11:20 am-9:10 pm

1 stop10h 50m

Panama City Tocumen Intl

Wed 6/11

5:25 pm-9:50 am

1 stop15h 25m

$267

MiamiPanama City

MIA - PTY

MIAPTY

Miami

Fri 6/13

6:20 am-8:30 am

Nonstop3h 10m

Panama City Tocumen Intl

Mon 6/16

10:05 pm-9:50 am

1 stop10h 45m

$334

MiamiPanama City

MIA - PTY

MIAPTY

Miami

Tue 6/17

10:30 am-1:00 pm

Nonstop3h 30m

Panama City Tocumen Intl

Mon 6/23

1:50 pm-5:55 pm

Nonstop3h 05m

$339

MiamiPanama City

MIA - PTY

MIAPTY

Miami

Sat 10/11

7:35 pm-12:47 pm

1 stop18h 12m

Panama City Tocumen Intl

Sat 10/18

2:12 pm-10:44 pm

1 stop7h 32m

$353

New YorkPanama City

JFK - PTY

JFKPTY

New York John F Kennedy Intl

Thu 5/8

8:59 pm-12:19 pm

2 stops16h 20m

Panama City Tocumen Intl

Mon 5/12

1:20 pm-7:52 am

2 stops17h 32m

$370

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Sun 6/1

7:50 pm-12:19 pm

2 stops17h 29m

Panama City Tocumen Intl

Mon 6/9

1:50 pm-10:59 pm

1 stop8h 09m

$370

New YorkPanama City

LGA - PTY

LGAPTY

New York LaGuardia

Wed 10/8

5:55 am-9:10 pm

2 stops16h 15m

Panama City Tocumen Intl

Tue 10/28

3:19 am-10:05 pm

2 stops17h 46m

$391

AtlantaPanama City

ATL - PTY

ATLPTY

Atlanta Hartsfield-Jackson

Mon 6/23

8:56 am-9:10 pm

2 stops13h 14m

Panama City Tocumen Intl

Thu 6/26

10:05 pm-2:10 pm

2 stops15h 05m

$394

AtlantaPanama City

ATL - PTY

ATLPTY

Atlanta Hartsfield-Jackson

Tue 5/20

9:45 am-12:48 pm

Nonstop4h 03m

Panama City Tocumen Intl

Fri 5/23

2:13 pm-7:32 pm

Nonstop4h 19m

$397

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/21

Showing 1-10 of 60 results
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Best time to book a flight from USA to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from USA with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from the United States to Panama

What is the cheapest month to book a flight from USA to Panama?

Currently, October is the cheapest month in which you can book a flight from USA to Panama (average of $478). Flying from USA to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from US to PA?

Find hourly flight availability from USA to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 22, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from USA to Panama as you normally would.

Weekly flight availability from USA to Panama

Explore weekly flight availability from USA to Panama. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated April 22, 2025.

The most flights from US0 to PA0 are scheduled on a Monday (9 on average). You will have fewer flight options on Friday, which is when the least amount of flights are scheduled (8 on average).

Rainfall in Panama by month

Plan your trip to Panama by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama when rainfall is around 0.4 in.

Temperature in Panama by month

Plan your trip to Panama by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated April 22, 2025.
Read through reviews of airlines operating flights from USA to Panama, such as Delta, Copa Airlines and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,920 reviews

Overall

8.0

Boarding

8.2

Food

7.3

Comfort

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,920 reviews
Delta
8.0
Very good
7,920 reviews

Overall

8.0

Boarding

8.2

Food

7.3

Comfort

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.5
Good
1,408 reviews
Delta
8.0
Very good
7,920 reviews

Overall

8.0

Boarding

8.2

Food

7.3

Comfort

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,683 reviews
Delta
8.0
Very good
7,920 reviews

Overall

8.0

Boarding

8.2

Food

7.3

Comfort

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Turkish Airlines
7.3
Good
3,773 reviews
Delta
8.0
Very good
7,920 reviews

Overall

8.0

Boarding

8.2

Food

7.3

Comfort

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,920 reviews

Overall

8.0

Boarding

8.2

Food

7.3

Comfort

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from USA to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this USA to Panama flight route?

    Within the past month, 185 users have taken a look at flights from United States to Panama.

  • What are the cheapest airlines to fly from USA to Panama one-way?

    One-way options have recently been found by users for as low as $68 on American Airlines. Other airlines that offer cheap prices include Avianca from $118 and Copa Airlines from $154 one-way.

  • Can I find deals for flights from USA to Panama that include hotel bookings?

    Yes. In addition to deals on USA to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from USA to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from USA to Panama.

  • Can I find deals for business class flights from USA to Panama?

    Yes. Cheapflights offers flight deals from USA to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from USA to Panama?

    Currently, October is the cheapest month in which you can book a flight from USA to Panama (average of $478). Flying from USA to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for USA to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Dallas/Fort Worth to San José flights
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Miami to San José flights
Newark to San Salvador flights
O'Hare Intl to Panama City flights
George Bush Intcntl to San José flights
LaGuardia to Liberia flights
Orlando to San José flights
Miami to Managua flights
LaGuardia to Guatemala City flights
Dallas/Fort Worth to Panama City flights
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George Bush Intcntl to Guatemala City flights
Seattle to San José flights
Atlanta to Guatemala City flights
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Top 5 airlines flying from USA to Panama

Discover the top 5 airlines that operate flights from USA to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 22, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$148Average$512FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$203Average$662FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$237Average$586FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$285Average$679FlexibilityNo cancel feeOn-time69%
DeltaCheapest$316Average$647FlexibilityNo cancel feeOn-timeN/A

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