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$222+ Cheap flights from St. Louis (STL) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/19. Fares are subject to change and may not be available on all flights or dates of travel.
STL — PTY
Dec 27 — Jan 31
Fri 12/27
Fri 1/3
1 adult, Economy
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Cheap flight deals from St. Louis to Panama

Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Panama (PA0). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 22, 2024.

Round-trip from

$468
(United)

One-way from

$222
(American Airlines)
From Lambert-St Louis to Panama
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One-way flight from Lambert-St Louis to Panama
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Find flight deals from St. Louis to Panama

Cheapest flights from St. Louis to Panama
Explore the most affordable flight options available from St. Louis to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 22, 2024.

This United Airlines deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/235:30 pmSTL - PTY
2 stops22h 37mUnited Airlines
Tue 1/214:40 pmPTY - STL
2 stops22h 34mUnited Airlines
Deal found 12/22$549
This American Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/272:27 pmSTL - PTY
2 stops21h 53mAmerican Airlines
Tue 1/74:40 pmPTY - STL
2 stops21h 17mAmerican Airlines
Deal found 12/21$974
This Kiwi.com deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/294:27 pmSTL - PTY
2 stops14h 43mMultiple Airlines
Mon 12/3012:03 pmPTY - STL
1 stop28h 18mMultiple Airlines
Deal found 12/21$1,129

Find flights from St. Louis to Panama within your budget

Customize your flight search to find flights from St. Louis to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 22, 2024.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Wed 3/12

10:55 am-6:38 pm

1 stop7h 43m

Panama City Tocumen Intl

Thu 3/20

10:55 pm-2:33 pm

2 stops15h 38m

$468

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Wed 2/12

6:29 pm-3:50 pm

2 stops20h 21m

Panama City Tocumen Intl

Thu 2/20

4:40 pm-11:40 pm

1 stop8h 00m

$473

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Sun 1/19

4:28 pm-12:35 pm

2 stops19h 07m

Panama City Tocumen Intl

Sat 1/25

5:25 pm-2:43 pm

3 stops22h 18m

$679

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Tue 3/11

6:00 am-12:55 pm

1 stop6h 55m

Panama City Tocumen Intl

Wed 3/19

2:20 pm-11:31 pm

1 stop9h 11m

$795

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Mon 1/20

8:15 am-12:35 pm

3 stops27h 20m

Panama City Tocumen Intl

Thu 1/30

1:30 pm-10:24 am

2 stops21h 54m

$954

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Sun 1/19

5:49 pm-3:49 pm

2 stops21h 00m

$222

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Sun 1/19

4:36 pm-7:38 pm

1 stop26h 02m

$236

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Sun 1/19

9:44 am-12:35 pm

3 stops25h 51m

$579

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/22

Best time to book a flight from St. Louis to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from St. Louis to Panama

Get recent, data-driven insights about flights from St. Louis to Panama including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from St. Louis to Panama?

Currently, October is the cheapest month in which you can book a flight from St. Louis to Panama (average of $478). Flying from St. Louis to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from STL to PA?

Find hourly flight availability from St. Louis to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 22, 2024.

When flying from St. Louis to Panama, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Panama by month

Plan your trip to Panama by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama when rainfall is around 0.4 in.

Temperature in Panama by month

Plan your trip to Panama by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated December 22, 2024.
Read through reviews of airlines operating flights from St. Louis to Panama, such as United Airlines and American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
8,594 reviews

Boarding

8.2

Entertainment

7.9

Comfort

8.0

Crew

8.6

Food

7.3

Overall

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta
8.0
Very good
8,594 reviews
Delta
8.0
Very good
8,594 reviews

Boarding

8.2

Entertainment

7.9

Comfort

8.0

Crew

8.6

Food

7.3

Overall

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

United Airlines
7.4
Good
9,028 reviews
Delta
8.0
Very good
8,594 reviews

Boarding

8.2

Entertainment

7.9

Comfort

8.0

Crew

8.6

Food

7.3

Overall

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,594 reviews

Boarding

8.2

Entertainment

7.9

Comfort

8.0

Crew

8.6

Food

7.3

Overall

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Avianca
7.0
Good
2,648 reviews
Delta
8.0
Very good
8,594 reviews

Boarding

8.2

Entertainment

7.9

Comfort

8.0

Crew

8.6

Food

7.3

Overall

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to Panama?

    For a flight from St. Louis to Panama, you will be flying from Lambert-St Louis. Lambert-St Louis (STL) is just 12.7 mi from the center of the city.

  • What are the cheapest airlines to fly from St. Louis to Panama one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $222. United Airlines flights start at $236 while deals on Avianca start at $579 one-way.

  • Can I find deals for flights from St. Louis to Panama that include hotel bookings?

    Yes. In addition to deals on St. Louis to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Panama.

  • Can I find deals for business class flights from St. Louis to Panama?

    Yes. Cheapflights offers flight deals from St. Louis to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Panama?

    Currently, October is the cheapest month in which you can book a flight from St. Louis to Panama (average of $478). Flying from St. Louis to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for St. Louis to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from St. Louis to Panama

Discover the top 3 airlines that operate flights from St. Louis to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 22, 2024.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$351Average$533FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$414Average$541FlexibilityNo cancel feeOn-time71%
DeltaCheapest$431Average$560FlexibilityNo cancel feeOn-timeN/A
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