Panama

$204+ Cheap flights from South Carolina to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/31. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — PTY
Nov 26 — Dec 31
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Cheap flight deals from South Carolina to Panama

Discover tips and strategies to find the most affordable flight options for your journey from South Carolina (USSC) to Panama (PA0). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 21, 2024.

Find flight deals from South Carolina to Panama

Cheapest flights from South Carolina to Panama
Explore the most affordable flight options available from South Carolina to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 21, 2024.

This American Airlines deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/57:53 pmGSP - PTY
2 stops19h 32mAmerican Airlines
Thu 12/124:15 pmPTY - GSP
2 stops18h 22mAmerican Airlines
Deal found 11/21$397
This United Airlines deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/56:45 amGSP - PTY
1 stop12h 53mUnited Airlines
Thu 12/128:55 amPTY - GSP
1 stop14h 33mUnited Airlines
Deal found 11/21$442
This Kiwi.com deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/61:26 pmCLT - PTY
1 stop7h 11mMultiple Airlines
Mon 12/98:01 amPTY - CLT
1 stop8h 49mMultiple Airlines
Deal found 11/21$514
This United Airlines deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/56:30 amCLT - PTY
1 stop13h 08mUnited Airlines
Thu 12/1211:55 pmPTY - CLT
1 stop9h 04mUnited Airlines
Deal found 11/21$516
This American Airlines deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/267:41 pmMYR - PTY
2 stops18h 09mAmerican Airlines
Tue 12/32:50 pmPTY - MYR
2 stops19h 43mAmerican Airlines
Deal found 11/21$547
This American Airlines deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/610:45 pmCLT - PTY
1 stop16h 40mAmerican Airlines
Fri 12/132:56 pmPTY - CLT
1 stop16h 59mAmerican Airlines
Deal found 11/21$556
This Avianca Connect deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/266:11 amMYR - PTY
2 stops14h 49mMultiple Airlines
Mon 12/23:19 amPTY - MYR
2 stops17h 39mMultiple Airlines
Deal found 11/21$603
This American Airlines deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/296:14 pmSAV - PTY
2 stops19h 36mAmerican Airlines
Mon 12/22:50 pmPTY - SAV
2 stops19h 41mAmerican Airlines
Deal found 11/21$811
This American Airlines deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/275:00 amAGS - PTY
2 stops8h 50mAmerican Airlines
Sun 12/12:50 pmPTY - AGS
2 stops19h 49mAmerican Airlines
Deal found 11/19$853
This Delta deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/267:05 amCLT - PTY
1 stop6h 42mDelta
Sat 11/308:25 amPTY - CLT
1 stop11h 10mDelta
Deal found 11/21$903
This Avianca deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/510:10 amCLT - PTY
2 stops14h 50mAvianca
Wed 12/113:19 amPTY - CLT
2 stops15h 23mAvianca
Deal found 11/21$930
This American Airlines deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/187:54 pmCAE - PTY
2 stops17h 26mAmerican Airlines
Wed 12/252:10 pmPTY - CAE
2 stops22h 25mAmerican Airlines
Deal found 11/20$939

Find flights from South Carolina to Panama within your budget

Customize your flight search to find flights from South Carolina to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,612,795 searches. Data last updated November 21, 2024.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Mon 5/5

7:56 pm-12:30 pm

2 stops17h 34m

Panama City Tocumen Intl

Thu 5/8

1:50 pm-10:28 am

2 stops19h 38m

$377

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Wed 1/8

6:26 pm-1:29 pm

2 stops19h 03m

Panama City Tocumen Intl

Tue 1/21

2:35 pm-10:34 am

2 stops19h 59m

$397

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Mon 1/13

11:05 am-8:02 pm

1 stop8h 57m

Panama City Tocumen Intl

Mon 1/27

10:00 am-9:05 pm

1 stop11h 05m

$436

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Thu 12/5

6:45 am-7:38 pm

1 stop12h 53m

Panama City Tocumen Intl

Thu 12/12

8:55 am-11:28 pm

1 stop14h 33m

$442

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Wed 1/15

6:00 am-3:49 pm

1 stop9h 49m

Panama City Tocumen Intl

Fri 1/31

2:35 pm-11:51 pm

1 stop9h 16m

$456

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Thu 1/30

6:07 pm-1:29 pm

2 stops19h 22m

Panama City Tocumen Intl

Thu 2/6

4:40 pm-10:40 am

2 stops18h 00m

$461

SavannahPanama City

SAV - PTY

SAVPTY

Savannah/Hilton Head

Thu 1/9

7:00 am-5:07 pm

1 stop10h 07m

Panama City Tocumen Intl

Tue 2/11

4:40 pm-9:41 pm

1 stop29h 01m

$465

SavannahPanama City

SAV - PTY

SAVPTY

Savannah/Hilton Head

Thu 1/9

7:40 pm-3:49 pm

2 stops20h 09m

Panama City Tocumen Intl

Tue 2/11

2:35 pm-11:20 pm

1 stop8h 45m

$501

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Fri 12/6

1:26 pm-8:37 pm

1 stop7h 11m

Panama City Tocumen Intl

Mon 12/9

8:01 am-4:50 pm

1 stop8h 49m

$514

ColumbiaPanama City

CAE - PTY

CAEPTY

Columbia Metropolitan

Fri 1/17

7:44 pm-1:29 pm

2 stops17h 45m

Panama City Tocumen Intl

Sun 2/2

4:40 pm-3:44 pm

2 stops23h 04m

$517

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/20

Showing 1-10 of 31 results
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Best time to book a flight from South Carolina to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from South Carolina to Panama

Get recent, data-driven insights about flights from South Carolina to Panama including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from South Carolina to Panama?

Currently, November is the cheapest month in which you can book a flight from South Carolina to Panama (average of $468). Flying from South Carolina to Panama in December is currently the most expensive (average of $564). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to PA?

Find hourly flight availability from South Carolina to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 21, 2024.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Panama as you normally would.

Rainfall in Panama by month

Plan your trip to Panama by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama when rainfall is around 0.4 in.

Temperature in Panama by month

Plan your trip to Panama by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated November 21, 2024.
Read through reviews of airlines operating flights from South Carolina to Panama, such as United Airlines, American Airlines and Delta. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
8.0
Very good
8,755 reviews

Comfort

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

8.0
Very good
8,755 reviews
8.0
Very good
8,755 reviews

Comfort

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

7.8
Good
1,779 reviews
8.0
Very good
8,755 reviews

Comfort

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

7.4
Good
9,172 reviews
8.0
Very good
8,755 reviews

Comfort

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

7.2
Good
10,000 reviews
8.0
Very good
8,755 reviews

Comfort

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

7.0
Good
2,794 reviews
8.0
Very good
8,755 reviews

Comfort

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What are the cheapest airlines to fly from South Carolina to Panama one-way?

    The cheapest airline one-way is United Airlines, with whom users have recently found tickets for as low as $226. However, be on the lookout for offers from American Airlines and Delta, as they are both options that can get you from South Carolina to Panama for a low price.

  • Can I find deals for flights from South Carolina to Panama that include hotel bookings?

    Yes. In addition to deals on South Carolina to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Panama.

  • Can I find deals for business class flights from South Carolina to Panama?

    Yes. Cheapflights offers flight deals from South Carolina to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Panama?

    Currently, November is the cheapest month in which you can book a flight from South Carolina to Panama (average of $468). Flying from South Carolina to Panama in December is currently the most expensive (average of $564). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Carolina to Panama

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from South Carolina to Panama

Discover the top 3 airlines that operate flights from South Carolina to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,612,795 searches. Data last updated November 21, 2024.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$281Average$404FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$284Average$535FlexibilityNo cancel feeOn-time71%
DeltaCheapest$299Average$526FlexibilityNo cancel feeOn-timeN/A
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