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$204+ Cheap flights from San Francisco (SFO) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/12. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — PTY
Mar 31 — Apr 71
Mon 3/31
Mon 4/7
1 adult, Economy
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Cheap flight deals from San Francisco to Panama

Keep the following information in mind while searching for San Francisco to Panama flight deals. Data was last updated March 26, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$513
(Cheapflightsfares)

One-way from

$204
(Cheapflightsfares)

Popular in

December

Cheapest in

July

Average price

$662

Good round-trip deal

$610 or less

Good one-way deal

$293 or less
Provider with most accurate pricing for San Francisco-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for San Francisco-Panama City Tocumen Intl flights.
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From San Francisco to Panama
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One-way flight from San Francisco to Panama
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Highest demand for flights based on searches. 16% potential increase in price ($135 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($40 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Price to beat on a round-trip flight from San Francisco to Panama.
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Price to beat on a one-way flight from San Francisco to Panama.
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Find flight deals from San Francisco to Panama

Cheapest flights from San Francisco to Panama
Explore the most affordable flight options available from San Francisco to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 26, 2025.

This KAYAK deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/271:37 amSFO - PTY
Nonstop7h 04mCopa Airlines
Sun 6/85:50 pmPTY - SFO
Nonstop7h 50mCopa Airlines
Deal found 3/25$513
This Cheapflightsfares deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/292:30 amSFO - PTY
2 stops16h 40mAvianca
Fri 4/43:25 amPTY - SFO
2 stops21h 20mAvianca
Deal found 3/25$514
This United Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/164:35 pmSFO - PTY
1 stop19h 39mUnited Airlines
Sat 5/313:15 pmPTY - SFO
Nonstop7h 43mUnited Airlines
Deal found 3/25$517
This Copa Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/81:37 amSFO - DAV
1 stop13h 51mCopa Airlines
Fri 5/169:44 amDAV - SFO
1 stop15h 56mCopa Airlines
Deal found 3/25$554
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/82:30 amSFO - PTY
1 stop10h 15mMultiple Airlines
Mon 4/143:25 amPTY - SFO
2 stops20h 30mMultiple Airlines
Deal found 3/25$596
This American Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/411:55 pmSFO - PTY
2 stops12h 20mAmerican Airlines
Tue 7/81:50 pmPTY - SFO
2 stops22h 37mAmerican Airlines
Deal found 3/26$648
This United Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/812:43 amSFO - DAV
2 stops14h 45mUnited Airlines
Fri 5/169:44 amDAV - SFO
2 stops35h 47mUnited Airlines
Deal found 3/25$947

Cheapflights Fare Finder

Customize your flight search to find flights from San Francisco to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 26, 2025.
Use the filters below to find and compare flights from San Francisco to Panama that are best for you.

Fly from

San Francisco

Fly to

Panama

Route

Depart

Return

Price

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Tue 5/27

1:37 am-10:41 am

Nonstop7h 04m

Panama City Tocumen Intl

Sun 6/8

5:50 pm-11:40 pm

Nonstop7h 50m

$513

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Mon 4/7

12:05 am-9:10 pm

2 stops19h 05m

Panama City Tocumen Intl

Mon 4/14

10:05 pm-12:35 pm

2 stops16h 30m

$514

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Fri 5/16

4:35 pm-2:14 pm

1 stop19h 39m

Panama City Tocumen Intl

Sat 5/31

3:15 pm-8:58 pm

Nonstop7h 43m

$517

San FranciscoDavid

SFO - DAV

SFODAV

San Francisco

Thu 5/8

1:37 am-5:28 pm

1 stop13h 51m

David Enrique Malek

Fri 5/16

9:44 am-11:40 pm

1 stop15h 56m

$554

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Tue 4/8

2:30 am-2:45 pm

1 stop10h 15m

Panama City Tocumen Intl

Mon 4/14

3:25 am-9:55 pm

2 stops20h 30m

$596

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Fri 7/4

11:55 pm-2:15 pm

2 stops12h 20m

Panama City Tocumen Intl

Tue 7/8

1:50 pm-10:27 am

2 stops22h 37m

$648

San FranciscoDavid

SFO - DAV

SFODAV

San Francisco

Thu 5/8

12:43 am-5:28 pm

2 stops14h 45m

David Enrique Malek

Fri 5/16

9:44 am-7:31 pm

2 stops35h 47m

$947

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Mon 5/12

12:05 am-2:45 pm

1 stop12h 40m

$204

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Tue 5/13

2:18 pm-10:21 am

1 stop18h 03m

$302

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Mon 7/14

10:55 am-8:10 pm

Nonstop7h 15m

$525

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/26

Showing 1-10 of 14 results
1
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Best time to book a flight from San Francisco to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Panama

What is the cheapest month to book a flight from San Francisco to Panama?

Currently, October is the cheapest month in which you can book a flight from San Francisco to Panama (average of $478). Flying from San Francisco to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SFO to PA?

Find hourly flight availability from San Francisco to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 26, 2025.

When flying from San Francisco to Panama, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 17% versus a flight in the morning.

What is the cheapest day to fly from San Francisco to Panama?

Use this chart to determine the cheapest time to fly round-trip from San Francisco to Panama. Price data was last updated on June 30, 2024.

Travelers seeking maximum savings on their San Francisco to Panama flight should consider departing on Tuesday evenings when fares are most often at their lowest. Saturday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Rainfall in Panama by month

Plan your trip to Panama by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama when rainfall is around 0.4 in.

Temperature in Panama by month

Plan your trip to Panama by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated March 26, 2025.
To help decide which airline to fly from San Francisco to Panama, see what other customers have to say about Delta, Copa Airlines and United Airlines. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,891 reviews

Overall

8.0

Boarding

8.2

Comfort

8.0

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,891 reviews
Delta
8.0
Very good
7,891 reviews

Overall

8.0

Boarding

8.2

Comfort

8.0

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.6
Good
1,393 reviews
Delta
8.0
Very good
7,891 reviews

Overall

8.0

Boarding

8.2

Comfort

8.0

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,608 reviews
Delta
8.0
Very good
7,891 reviews

Overall

8.0

Boarding

8.2

Comfort

8.0

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,891 reviews

Overall

8.0

Boarding

8.2

Comfort

8.0

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Avianca
6.7
Okay
2,298 reviews
Delta
8.0
Very good
7,891 reviews

Overall

8.0

Boarding

8.2

Comfort

8.0

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from San Francisco to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from San Francisco to Panama?

    If you book a flight to Panama from San Francisco, you will be flying from San Francisco, which is the city’s only airport. San Francisco (SFO) is located 11.8 mi from the center of San Francisco.

  • How popular is this San Francisco to Panama flight route?

    Within the past month, 173 users have taken a look at flights from San Francisco to Panama.

  • What are the cheapest airlines to fly from San Francisco to Panama one-way?

    $204 is the cheapest one-way deal found within the past few days, from Avianca. You may also be able to find cheap deals on United Airlines and Copa Airlines, with prices starting from $525 and $582, respectively.

  • What are the most popular routes from San Francisco to Panama?

    The most popular route from San Francisco to Panama is San Francisco - Panama City Tocumen Intl. You may also consider San Francisco - David Enrique Malek or San Francisco - Bocas Del Toro.

  • What are the most reliable airlines from San Francisco to Panama?

    No one likes to see their flight delayed. When booking a flight from San Francisco to Panama consider choosing EVA Air (90%), United Airlines (90%) or Copa Airlines (89%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from San Francisco to Panama?

    The cheapest flight price from San Francisco to Panama is $224. On average you can expect to pay $2,394. The most popular route, (San Francisco - Panama City Tocumen Intl), can usually be booked for $494.

  • Can I find deals for flights from San Francisco to Panama that include hotel bookings?

    Yes. In addition to deals on San Francisco to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Panama.

  • Can I find deals for business class flights from San Francisco to Panama?

    Yes. Cheapflights offers flight deals from San Francisco to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco to Panama?

    Currently, October is the cheapest month in which you can book a flight from San Francisco to Panama (average of $478). Flying from San Francisco to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 5 airlines flying from San Francisco to Panama

Discover the top 5 airlines that operate flights from San Francisco to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 26, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$401Average$647FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$477Average$737FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$540Average$724FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$544Average$596FlexibilityNo cancel feeOn-time71%
DeltaCheapest$547Average$903FlexibilityNo cancel feeOn-timeN/A
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