Panama

$218+ Cheap flights from San Francisco (SFO) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/29. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — PTY
abr. 20 — abr. 271
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Cheap flight deals from San Francisco to Panama

Keep the following information in mind while searching for San Francisco to Panama flight deals. Data was last updated abril 15, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$480
(Vliegwinkel)

One-way from

$218
(Cheapflightsfares)

Popular in

December

Cheapest in

September

Average price

$647

Good round-trip deal

$602 or less

Good one-way deal

$264 or less
Provider with most accurate pricing for San Francisco-Panama City Tocumen Intl flight deals.
Provider most trusted by Cheapflights users for San Francisco-Panama City Tocumen Intl flights.
From San Francisco to Panama
One-way flight from San Francisco to Panama
Highest demand for flights based on searches. 16% potential increase in price ($132 potential increase over avg. RT price).
Cheapest flight prices on average. 5% potential price decrease ($39 potential savings vs. average RT price).
Average for round-trip flights in April 2025
Price to beat on a round-trip flight from San Francisco to Panama.
Price to beat on a one-way flight from San Francisco to Panama.

Find flight deals from San Francisco to Panama

Cheapest flights from San Francisco to Panama
Explore the most affordable flight options available from San Francisco to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on abril 15, 2025.

This Gotogate deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/1512:05 amSFO - PTY
2 stops19h 05mAvianca
vie. 5/2311:05 amPTY - SFO
2 stops13h 40mAvianca
Deal found 4/15$495
This Delta deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 6/279:35 pmSFO - PTY
1 stop19h 27mDelta
jue. 7/102:12 pmPTY - SFO
1 stop12h 24mDelta
Deal found 4/15$527
This Copa Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 7/311:28 amSFO - PTY
Nonstop7h 13mCopa Airlines
sáb. 8/95:50 pmPTY - SFO
Nonstop7h 50mCopa Airlines
Deal found 4/14$528
This United Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/2810:55 amSFO - PTY
Nonstop7h 15mUnited Airlines
dom. 6/83:15 pmPTY - SFO
Nonstop7h 43mUnited Airlines
Deal found 4/15$529
This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/1612:31 amSFO - PTY
2 stops11h 49mAmerican Airlines
jue. 12/42:45 pmPTY - SFO
2 stops21h 23mAmerican Airlines
Deal found 4/15$648
This Gurufare deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 6/2212:05 amSFO - PTY
1 stop12h 40mMultiple Airlines
lun. 6/301:15 pmPTY - SFO
1 stop22h 05mMultiple Airlines
Deal found 4/15$748
This Copa Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/141:37 amSFO - DAV
1 stop13h 51mCopa Airlines
dom. 5/259:44 amDAV - SFO
1 stop15h 56mCopa Airlines
Deal found 4/15$968
This Kiwi.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 5/1312:05 amSFO - BOC
2 stops30h 40mMultiple Airlines
mié. 5/216:20 pmBOC - SFO
1 stop31h 20mMultiple Airlines
Deal found 4/15$1,019
This United Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 5/1312:43 amSFO - DAV
2 stops14h 45mUnited Airlines
mié. 5/219:44 amDAV - SFO
2 stops52h 25mUnited Airlines
Deal found 4/15$1,060

Cheapflights Fare Finder

Customize your flight search to find flights from San Francisco to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 15, 2025.
Use the filters below to find and compare flights from San Francisco to Panama that are best for you.

Fly from

San Francisco

Fly to

Panama

Route

Depart

Return

Price

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

jue. 5/15

12:05 am-9:10 pm

2 stops19h 05m

Panama City Tocumen Intl

vie. 5/23

11:05 am-10:45 pm

2 stops13h 40m

$495

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

vie. 6/27

9:35 pm-7:02 pm

1 stop19h 27m

Panama City Tocumen Intl

jue. 7/10

2:12 pm-12:36 am

1 stop12h 24m

$527

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

jue. 7/31

1:28 am-10:41 am

Nonstop7h 13m

Panama City Tocumen Intl

sáb. 8/9

5:50 pm-11:40 pm

Nonstop7h 50m

$528

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

mié. 5/28

10:55 am-8:10 pm

Nonstop7h 15m

Panama City Tocumen Intl

dom. 6/8

3:15 pm-8:58 pm

Nonstop7h 43m

$529

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

lun. 6/23

3:23 pm-1:00 pm

2 stops19h 37m

Panama City Tocumen Intl

lun. 6/30

1:50 pm-9:23 am

2 stops21h 33m

$648

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

dom. 6/22

12:05 am-2:45 pm

1 stop12h 40m

Panama City Tocumen Intl

lun. 6/30

1:15 pm-9:20 am

1 stop22h 05m

$748

San FranciscoDavid

SFO - DAV

SFODAV

San Francisco

mié. 5/14

1:37 am-5:28 pm

1 stop13h 51m

David Enrique Malek

dom. 5/25

9:44 am-11:40 pm

1 stop15h 56m

$968

San FranciscoBocas del Toro

SFO - BOC

SFOBOC

San Francisco

mar. 5/13

12:05 am-8:45 am

2 stops30h 40m

Bocas Del Toro

mié. 5/21

6:20 pm-11:40 pm

1 stop31h 20m

$1,019

San FranciscoDavid

SFO - DAV

SFODAV

San Francisco

mar. 5/13

12:43 am-5:28 pm

2 stops14h 45m

David Enrique Malek

mié. 5/21

9:44 am-12:09 pm

2 stops52h 25m

$1,060

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

mar. 4/29

12:05 am-10:25 am

1 stop8h 20m

$218

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/15

Showing 1-10 of 13 results
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Best time to book a flight from San Francisco to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Panama

What is the cheapest month to book a flight from San Francisco to Panama?

Currently, October is the cheapest month in which you can book a flight from San Francisco to Panama (average of $478). Flying from San Francisco to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SFO to PA?

Find hourly flight availability from San Francisco to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated abril 15, 2025.

When flying from San Francisco to Panama, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 17% versus a flight in the morning.

What is the cheapest day to fly from San Francisco to Panama?

Use this chart to determine the cheapest time to fly round-trip from San Francisco to Panama. Price data was last updated on June 30, 2024.

Travelers seeking maximum savings on their San Francisco to Panama flight should consider departing on Tuesday evenings when fares are most often at their lowest. Saturday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from San Francisco to Panama

Explore weekly flight availability from San Francisco to Panama. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated abril 15, 2025.

The most flights from SFO to PA0 are scheduled on a Tuesday (4 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (3 on average).

Rainfall in Panama by month

Plan your trip to Panama by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama when rainfall is around 0.4 in.

Temperature in Panama by month

Plan your trip to Panama by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated abril 15, 2025.
To help decide which airline to fly from San Francisco to Panama, see what other customers have to say about Delta, Copa Airlines and United Airlines. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
8.0
Very good

Overall

8.0

Boarding

8.2

Crew

8.5

Entertainment

7.9

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
8.0
Very good
8.0
Very good

Overall

8.0

Boarding

8.2

Crew

8.5

Entertainment

7.9

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
8.0
Very good

Overall

8.0

Boarding

8.2

Crew

8.5

Entertainment

7.9

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
8.0
Very good

Overall

8.0

Boarding

8.2

Crew

8.5

Entertainment

7.9

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
8.0
Very good

Overall

8.0

Boarding

8.2

Crew

8.5

Entertainment

7.9

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
8.0
Very good

Overall

8.0

Boarding

8.2

Crew

8.5

Entertainment

7.9

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from San Francisco to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from San Francisco to Panama?

    If you book a flight to Panama from San Francisco, you will be flying from San Francisco, which is the city’s only airport. San Francisco (SFO) is located 11.8 mi from the center of San Francisco.

  • How popular is this San Francisco to Panama flight route?

  • What are the cheapest airlines to fly from San Francisco to Panama one-way?

    $218 is the cheapest one-way deal found within the past few days, from Avianca. You may also be able to find cheap deals on United Airlines and Copa Airlines, with prices starting from $441 and $620, respectively.

  • What are the most popular routes from San Francisco to Panama?

  • What are the most reliable airlines from San Francisco to Panama?

    No one likes to see their flight delayed. When booking a flight from San Francisco to Panama consider choosing EVA Air (88%), United Airlines (88%) or Copa Airlines (88%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from San Francisco to Panama?

    The cheapest flight price from San Francisco to Panama is $222. On average you can expect to pay $1,248. The most popular route, (San Francisco - Panama City Tocumen Intl), can usually be booked for $504.

  • Can I find deals for flights from San Francisco to Panama that include hotel bookings?

    Yes. In addition to deals on San Francisco to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Panama.

  • Can I find deals for business class flights from San Francisco to Panama?

    Yes. Cheapflights offers flight deals from San Francisco to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco to Panama?

    Currently, October is the cheapest month in which you can book a flight from San Francisco to Panama (average of $478). Flying from San Francisco to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for San Francisco to Panama

See prices for flight routes from nearby airports that may be better suited for you.

Top 5 airlines flying from San Francisco to Panama

Discover the top 5 airlines that operate flights from San Francisco to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$403Average$646FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$477Average$674FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$540Average$719FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$544Average$596FlexibilityNo cancel feeOn-time71%
DeltaCheapest$547Average$836FlexibilityNo cancel feeOn-timeN/A

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