HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Panama

$175+ Cheap flights from San Diego (SAN) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/27. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — PTY
Apr 2 — Apr 91
Wed 4/2
Wed 4/9
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from San Diego to Panama with Cheapflights

1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”
2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.
3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from San Diego to Panama

Keep the following information in mind while searching for San Diego to Panama flight deals. Data was last updated March 28, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$389
(Copa Airlines)

One-way from

$175
(Trip.com)

Popular in

December

Cheapest in

May

Average price

$646

Good round-trip deal

$380 or less

Good one-way deal

$214 or less
Provider with most accurate pricing for San Diego-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for San Diego-Panama City Tocumen Intl flights.
Search Deals
From San Diego to Panama
Search Deals
One-way flight from San Diego to Panama
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($28 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2025
Search Deals
Price to beat on a round-trip flight from San Diego to Panama.
Search Deals
Price to beat on a one-way flight from San Diego to Panama.
Search Deals

Find flight deals from San Diego to Panama

Cheapest flights from San Diego to Panama
Explore the most affordable flight options available from San Diego to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 28, 2025.

This Copa Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/179:03 pmSAN - PTY
Nonstop6h 17mCopa Airlines
Sun 9/211:15 pmPTY - SAN
Nonstop6h 35mCopa Airlines
Deal found 3/27$389
This United Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/117:38 pmSAN - PTY
2 stops20h 59mUnited Airlines
Tue 10/1410:00 amPTY - SAN
1 stop13h 17mUnited Airlines
Deal found 3/26$403
This American Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/103:30 pmSAN - PTY
2 stops18h 55mAmerican Airlines
Fri 10/171:50 pmPTY - SAN
2 stops20h 44mAmerican Airlines
Deal found 3/26$469
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/79:40 pmSAN - PTY
1 stop13h 07mDelta
Sat 10/182:12 pmPTY - SAN
1 stop10h 34mDelta
Deal found 3/26$523
This Mytrip deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/138:08 amSAN - PTY
3 stops46h 47mMultiple Airlines
Sat 5/173:20 amPTY - SAN
3 stops46h 36mMultiple Airlines
Deal found 3/27$732
This United Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/237:10 pmSAN - DAV
3 stops44h 18mUnited Airlines
Sat 8/309:41 amDAV - SAN
2 stops36h 35mUnited Airlines
Deal found 3/27$1,097
This Ovago deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/810:45 amSAN - PTY
2 stops20h 40mAvianca
Sat 11/228:05 pmPTY - SAN
3 stops24h 44mAvianca
Deal found 3/27$1,335

Cheapflights Fare Finder

Customize your flight search to find flights from San Diego to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
Use the filters below to find and compare flights from San Diego to Panama that are best for you.

Fly from

San Diego

Fly to

Panama

Route

Depart

Return

Price

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Wed 9/17

9:03 pm-5:20 am

Nonstop6h 17m

Panama City Tocumen Intl

Sun 9/21

1:15 pm-5:50 pm

Nonstop6h 35m

$389

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Wed 9/17

5:01 pm-12:25 pm

2 stops17h 24m

Panama City Tocumen Intl

Sun 9/21

1:50 pm-8:28 am

2 stops20h 38m

$408

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Fri 8/8

7:27 pm-2:14 pm

2 stops16h 47m

Panama City Tocumen Intl

Sun 8/17

3:15 pm-12:15 am

1 stop11h 00m

$414

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Fri 4/18

10:30 pm-12:55 pm

1 stop12h 25m

Panama City Tocumen Intl

Fri 4/25

2:20 pm-11:27 pm

1 stop11h 07m

$587

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Tue 5/13

8:08 am-8:55 am

3 stops46h 47m

Panama City Tocumen Intl

Sat 5/17

3:20 am-11:56 pm

3 stops46h 36m

$732

San DiegoDavid

SAN - DAV

SANDAV

San Diego

Sat 8/23

7:10 pm-5:28 pm

3 stops44h 18m

David Enrique Malek

Sat 8/30

9:41 am-8:16 pm

2 stops36h 35m

$1,097

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Sun 5/11

10:30 am-10:25 am

3 stops21h 55m

Panama City Tocumen Intl

Sun 5/18

3:40 pm-9:35 am

2 stops19h 55m

$1,380

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Fri 6/27

6:15 am-6:37 pm

1 stop10h 22m

$175

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Fri 6/27

9:06 pm-5:20 am

Nonstop6h 14m

$176

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Wed 6/25

6:25 am-1:00 pm

2 stops28h 35m

$221

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/27

Showing 1-10 of 13 results
1
2

Best time to book a flight from San Diego to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from San Diego with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Diego to Panama

What is the cheapest month to book a flight from San Diego to Panama?

Currently, October is the cheapest month in which you can book a flight from San Diego to Panama (average of $478). Flying from San Diego to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAN to PA?

Find hourly flight availability from San Diego to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 28, 2025.

When flying from San Diego to Panama, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Panama by month

Plan your trip to Panama by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama when rainfall is around 0.4 in.

Temperature in Panama by month

Plan your trip to Panama by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated March 28, 2025.
Delta
8.0
Very good
7,897 reviews

Entertainment

7.9

Overall

8.0

Comfort

8.0

Food

7.3

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,897 reviews
Delta
8.0
Very good
7,897 reviews

Entertainment

7.9

Overall

8.0

Comfort

8.0

Food

7.3

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.5
Good
1,395 reviews
Delta
8.0
Very good
7,897 reviews

Entertainment

7.9

Overall

8.0

Comfort

8.0

Food

7.3

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,603 reviews
Delta
8.0
Very good
7,897 reviews

Entertainment

7.9

Overall

8.0

Comfort

8.0

Food

7.3

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,897 reviews

Entertainment

7.9

Overall

8.0

Comfort

8.0

Food

7.3

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Avianca
6.7
Okay
2,300 reviews
Delta
8.0
Very good
7,897 reviews

Entertainment

7.9

Overall

8.0

Comfort

8.0

Food

7.3

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from San Diego to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from San Diego to Panama?

    Located just 2.6 mi from the city center, San Diego (SAN) is the airport most travelers will use when flying to Panama from San Diego.

  • What are the cheapest airlines to fly from San Diego to Panama one-way?

    $175 is the cheapest one-way deal found within the past few days, from United Airlines. You may also be able to find cheap deals on Copa Airlines and American Airlines, with prices starting from $176 and $221, respectively.

  • What are the cheapest flights from San Diego to Panama?

    Looking for the cheapest flight from San Diego to Panama? While on average our users pay $1,043, our data indicates the cheapest price to be $176. The most popular route (San Diego - Panama City Tocumen Intl), is priced around $389.

  • Can I find deals for flights from San Diego to Panama that include hotel bookings?

    Yes. In addition to deals on San Diego to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Diego to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Diego to Panama.

  • Can I find deals for business class flights from San Diego to Panama?

    Yes. Cheapflights offers flight deals from San Diego to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Diego to Panama?

    Currently, October is the cheapest month in which you can book a flight from San Diego to Panama (average of $478). Flying from San Diego to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for San Diego to Panama

See prices for flight routes from nearby airports that may be better suited for you.
Los Angeles to San Salvador flights
Los Angeles to Guatemala City flights
Los Angeles to San José flights
Los Angeles to Liberia flights
San Francisco to San José flights
Ontario to San Salvador flights
Los Angeles to Panama City flights
Los Angeles to Philip S.W.Goldson flights
San Francisco to Liberia flights
Ontario to Guatemala City flights
San Francisco to Panama City flights
San Francisco to Guatemala City flights
Ontario to San José flights
Burbank to Guatemala City flights
San Francisco to Managua flights
Los Angeles to Managua flights
San Francisco to San Salvador flights
Burbank to San Salvador flights
Las Vegas to San José flights
Burbank to San José flights
Ontario to Liberia flights
Ontario to Panama City flights
Oakland to San José flights
Ontario to Philip S.W.Goldson flights
San Diego to San José flights
Los Angeles to San Pedro Sula flights
San Jose to San José flights
Las Vegas to San Salvador flights
San Francisco to Philip S.W.Goldson flights
Oakland to San Salvador flights
Santa Ana to San José flights
Las Vegas to Philip S.W.Goldson flights
Oakland to Guatemala City flights
San Diego to Philip S.W.Goldson flights
Sacramento to San José flights
Ontario to Managua flights
Sacramento to Liberia flights
Sacramento to Panama City flights
San Diego to Liberia flights
San Jose to Liberia flights
San Francisco to Coxen Hole flights
San Diego to Panama City flights
Las Vegas to Panama City flights
Ontario to San Pedro Sula flights
Los Angeles to Coxen Hole flights
Las Vegas to Guatemala City flights
San Jose to Guatemala City flights
San Diego to San Salvador flights
Sacramento to Guatemala City flights
San Jose to Philip S.W.Goldson flights

Top 4 airlines flying from San Diego to Panama

Discover the top 4 airlines that operate flights from San Diego to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$410Average$1,065FlexibilityNo cancel feeOn-time70%
DeltaCheapest$593Average$683FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$594Average$673FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$596Average$693FlexibilityNo cancel feeOn-time71%
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.