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$222+ Cheap flights from Ohio to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/31. Fares are subject to change and may not be available on all flights or dates of travel.
CLE — PTY
Apr 7 — Apr 141
Mon 4/7
Mon 4/14
1 adult, Economy
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Cheap flight deals from Ohio to Panama

Keep the following information in mind while searching for Ohio to Panama flight deals. Data was last updated April 2, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$431
(Avianca Connect)

One-way from

$222
(United Airlines)

Popular in

December

Cheapest in

September

Average price

$599
Provider with most accurate pricing for Cleveland Hopkins Intl-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Cleveland Hopkins Intl-Panama City Tocumen Intl flights.
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From Ohio to Panama
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One-way flight from Ohio to Panama
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Highest demand for flights based on searches. 4% potential increase in price ($29 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($16 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Ohio to Panama

Cheapest flights from Ohio to Panama
Explore the most affordable flight options available from Ohio to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 2, 2025.

This Avianca Connect deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/295:00 amDTW - PTY
2 stops17h 10mMultiple Airlines
Mon 5/53:25 amPTY - DTW
2 stops13h 12mMultiple Airlines
Deal found 4/1$431
This United deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/86:20 amCVG - PTY
1 stop8h 54mUnited Airlines
Tue 4/1510:00 amPTY - CVG
1 stop12h 44mUnited Airlines
Deal found 4/1$437
This Delta deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/137:00 amCMH - PTY
1 stop6h 48mDelta
Tue 5/202:13 pmPTY - CMH
1 stop8h 55mDelta
Deal found 4/1$437
This Delta deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/295:50 amPIT - PTY
1 stop8h 05mDelta
Tue 5/62:20 pmPTY - PIT
1 stop8h 53mDelta
Deal found 4/1$437
This United Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/136:00 amCMH - PTY
2 stops13h 37mUnited Airlines
Tue 5/207:55 amPTY - CMH
1 stop14h 46mUnited Airlines
Deal found 3/31$442
This United Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/297:25 amPIT - PTY
2 stops12h 12mUnited Airlines
Tue 5/67:55 amPTY - PIT
2 stops11h 40mUnited Airlines
Deal found 4/1$442
This Delta deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/266:00 amCLE - PTY
1 stop7h 48mDelta
Sat 5/318:00 amPTY - CLE
1 stop8h 26mDelta
Deal found 4/1$455
This Avianca Connect deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/167:00 amPIT - PTY
2 stops18h 10mMultiple Airlines
Tue 5/203:20 amPTY - PIT
2 stops18h 59mMultiple Airlines
Deal found 4/1$456
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/245:33 pmCVG - PTY
2 stops19h 42mAmerican Airlines
Mon 4/281:15 pmPTY - CVG
2 stops22h 41mAmerican Airlines
Deal found 4/1$460
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/262:00 pmCLE - PTY
2 stops23h 19mAmerican Airlines
Sat 5/311:20 pmPTY - CLE
2 stops19h 20mAmerican Airlines
Deal found 4/1$460
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/256:03 amPIT - PTY
1 stop7h 57mAmerican Airlines
Tue 7/81:50 pmPTY - PIT
1 stop8h 32mAmerican Airlines
Deal found 4/1$469
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/276:54 pmCMH - PTY
1 stop18h 25mAmerican Airlines
Sun 6/11:20 pmPTY - CMH
2 stops21h 36mAmerican Airlines
Deal found 4/1$470

Cheapflights Fare Finder

Customize your flight search to find flights from Ohio to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 2, 2025.
Use the filters below to find and compare flights from Ohio to Panama that are best for you.

Fly from

Ohio

Fly to

Panama

Route

Depart

Return

Price

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 4/29

5:00 am-9:10 pm

2 stops17h 10m

Panama City Tocumen Intl

Mon 5/5

3:25 am-5:37 pm

2 stops13h 12m

$431

CincinnatiPanama City

CVG - PTY

CVGPTY

Cincinnati Cinci./N. Kentucky

Tue 4/22

6:20 am-2:14 pm

1 stop8h 54m

Panama City Tocumen Intl

Tue 4/29

10:00 am-11:44 pm

1 stop12h 44m

$437

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Tue 5/13

7:00 am-12:48 pm

1 stop6h 48m

Panama City Tocumen Intl

Tue 5/20

2:13 pm-12:08 am

1 stop8h 55m

$437

PittsburghPanama City

PIT - PTY

PITPTY

Pittsburgh

Tue 4/29

5:50 am-12:55 pm

1 stop8h 05m

Panama City Tocumen Intl

Tue 5/6

2:20 pm-12:13 am

1 stop8h 53m

$437

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Tue 5/13

6:00 am-6:37 pm

2 stops13h 37m

Panama City Tocumen Intl

Tue 5/20

7:55 am-11:41 pm

1 stop14h 46m

$442

PittsburghPanama City

PIT - PTY

PITPTY

Pittsburgh

Tue 4/29

7:25 am-6:37 pm

2 stops12h 12m

Panama City Tocumen Intl

Tue 5/6

7:55 am-8:35 pm

2 stops11h 40m

$442

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Mon 5/26

6:00 am-12:48 pm

1 stop7h 48m

Panama City Tocumen Intl

Sat 5/31

8:00 am-5:26 pm

1 stop8h 26m

$455

PittsburghPanama City

PIT - PTY

PITPTY

Pittsburgh

Fri 5/16

7:00 am-12:10 am

2 stops18h 10m

Panama City Tocumen Intl

Tue 5/20

3:20 am-11:19 pm

2 stops18h 59m

$456

CincinnatiPanama City

CVG - PTY

CVGPTY

Cincinnati Cinci./N. Kentucky

Thu 4/24

5:33 pm-12:15 pm

2 stops19h 42m

Panama City Tocumen Intl

Mon 4/28

1:15 pm-12:56 pm

2 stops22h 41m

$460

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Mon 5/26

2:00 pm-12:19 pm

2 stops23h 19m

Panama City Tocumen Intl

Sat 5/31

1:20 pm-9:40 am

2 stops19h 20m

$460

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/31

Showing 1-10 of 35 results
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Best time to book a flight from Ohio to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Ohio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Ohio to Panama

What is the cheapest month to book a flight from Ohio to Panama?

Currently, October is the cheapest month in which you can book a flight from Ohio to Panama (average of $478). Flying from Ohio to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from OH to PA?

Find hourly flight availability from Ohio to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 2, 2025.

When flying from Ohio to Panama, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Panama by month

Plan your trip to Panama by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama when rainfall is around 0.4 in.

Temperature in Panama by month

Plan your trip to Panama by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated April 2, 2025.
Get a feel of what it's like to fly with Delta, United Airlines and American Airlines from Ohio to Panama by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,898 reviews

Crew

8.5

Entertainment

7.9

Boarding

8.2

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,898 reviews
Delta
8.0
Very good
7,898 reviews

Crew

8.5

Entertainment

7.9

Boarding

8.2

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,616 reviews
Delta
8.0
Very good
7,898 reviews

Crew

8.5

Entertainment

7.9

Boarding

8.2

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,898 reviews

Crew

8.5

Entertainment

7.9

Boarding

8.2

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Avianca
6.7
Okay
2,302 reviews
Delta
8.0
Very good
7,898 reviews

Crew

8.5

Entertainment

7.9

Boarding

8.2

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Ohio to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Ohio to Panama one-way?

    To fly one-way, consider booking your trip with United Airlines, which is currently one of the cheapest options available, starting at $222. Delta flights start at $222 while deals on American Airlines start at $228 one-way.

  • Can I find deals for flights from Ohio to Panama that include hotel bookings?

    Yes. In addition to deals on Ohio to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Ohio to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ohio to Panama.

  • Can I find deals for business class flights from Ohio to Panama?

    Yes. Cheapflights offers flight deals from Ohio to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Ohio to Panama?

    Currently, October is the cheapest month in which you can book a flight from Ohio to Panama (average of $478). Flying from Ohio to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Ohio to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Ohio to Panama

Discover the top 3 airlines that operate flights from Ohio to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 2, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$384Average$635FlexibilityNo cancel feeOn-time71%
DeltaCheapest$407Average$584FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$449Average$566FlexibilityNo cancel feeOn-time69%

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