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$147+ Cheap flights from North Carolina to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/11. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — PTY
Feb 25 — Mar 41
Tue 2/25
Tue 3/4
1 adult, Economy
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Cheap flight deals from North Carolina to Panama

Keep the following information in mind while searching for North Carolina to Panama flight deals. Data was last updated February 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$359
(Delta)

One-way from

$147
(Delta)

Popular in

December

Cheapest in

May

Average price

$537

Good round-trip deal

$349 or less

Good one-way deal

$158 or less
Provider with most accurate pricing for Charlotte Douglas-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Charlotte Douglas-Panama City Tocumen Intl flights.
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From North Carolina to Panama
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One-way flight from North Carolina to Panama
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Highest demand for flights based on searches. 16% potential increase in price ($113 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($31 potential savings vs. average RT price).
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Average for round-trip flights in February 2025
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Price to beat on a round-trip flight from North Carolina to Panama.
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Price to beat on a one-way flight from North Carolina to Panama.
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Find flight deals from North Carolina to Panama

Cheapest flights from North Carolina to Panama
Explore the most affordable flight options available from North Carolina to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/36:47 amORF - PTY
1 stop7h 15mDelta
Wed 3/53:27 pmPTY - ORF
1 stop8h 32mDelta
Deal found 2/20$359
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/36:00 amORF - PTY
1 stop13h 38mUnited Airlines
Wed 3/58:55 amPTY - ORF
2 stops24h 47mUnited Airlines
Deal found 2/20$364
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/266:16 amORF - PTY
1 stop9h 16mAmerican Airlines
Wed 4/23:50 pmPTY - ORF
1 stop6h 58mAmerican Airlines
Deal found 2/20$371
This Avianca Connect deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/1712:50 pmRDU - PTY
2 stops12h 30mMultiple Airlines
Mon 3/246:30 pmPTY - RDU
2 stops16h 59mMultiple Airlines
Deal found 2/19$398
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/68:53 amCLT - PTY
1 stop8h 33mMultiple Airlines
Sun 4/139:33 pmPTY - CLT
1 stop13h 41mMultiple Airlines
Deal found 2/20$418
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/225:02 pmTYS - PTY
2 stops20h 23mAmerican Airlines
Mon 10/271:50 pmPTY - TYS
1 stop8h 22mAmerican Airlines
Deal found 2/19$420
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/245:31 amGSO - PTY
1 stop7h 44mAmerican Airlines
Mon 4/281:15 pmPTY - GSO
2 stops22h 27mAmerican Airlines
Deal found 2/19$420
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/137:05 amGSO - PTY
1 stop6h 46mDelta
Sat 5/178:05 amPTY - GSO
1 stop7h 21mDelta
Deal found 2/19$435
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/47:48 pmMYR - PTY
2 stops17h 27mAmerican Airlines
Sat 5/101:20 pmPTY - MYR
2 stops21h 56mAmerican Airlines
Deal found 2/19$440
This Copa Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/164:18 pmRDU - PTY
Nonstop4h 28mCopa Airlines
Wed 4/238:57 amPTY - RDU
Nonstop4h 32mCopa Airlines
Deal found 2/20$441
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/58:20 pmRDU - PTY
2 stops16h 55mAmerican Airlines
Sat 4/121:15 pmPTY - RDU
2 stops20h 18mAmerican Airlines
Deal found 2/19$445
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/77:00 amCLT - PTY
1 stop6h 51mDelta
Tue 5/272:02 pmPTY - CLT
1 stop8h 54mDelta
Deal found 2/20$447

Find flights from North Carolina to Panama within your budget

Customize your flight search to find flights from North Carolina to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.

Fly from

North Carolina

Fly to

Panama

Route

Depart

Return

Price

NorfolkPanama City

ORF - PTY

ORFPTY

Norfolk

Mon 3/3

6:47 am-2:02 pm

1 stop7h 15m

Panama City Tocumen Intl

Wed 3/5

3:27 pm-11:59 pm

1 stop8h 32m

$359

NorfolkPanama City

ORF - PTY

ORFPTY

Norfolk

Mon 3/3

6:00 am-7:38 pm

1 stop13h 38m

Panama City Tocumen Intl

Wed 3/5

8:55 am-9:42 am

2 stops24h 47m

$364

NorfolkPanama City

ORF - PTY

ORFPTY

Norfolk

Wed 3/26

6:16 am-12:15 pm

1 stop6h 59m

Panama City Tocumen Intl

Wed 4/2

3:50 pm-11:48 pm

1 stop6h 58m

$371

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Mon 3/17

12:50 pm-12:20 am

2 stops12h 30m

Panama City Tocumen Intl

Mon 3/24

6:30 pm-12:29 pm

2 stops16h 59m

$398

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Sun 4/6

8:53 am-4:26 pm

1 stop8h 33m

Panama City Tocumen Intl

Sun 4/13

9:33 pm-12:14 pm

1 stop13h 41m

$418

KnoxvillePanama City

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

Sun 4/13

7:54 pm-12:15 pm

2 stops17h 21m

Panama City Tocumen Intl

Wed 4/16

1:10 pm-10:38 am

2 stops20h 28m

$420

GreensboroPanama City

GSO - PTY

GSOPTY

Greensboro/H. Point

Thu 4/24

5:31 am-12:15 pm

1 stop7h 44m

Panama City Tocumen Intl

Mon 4/28

1:15 pm-12:42 pm

2 stops22h 27m

$420

GreensboroPanama City

GSO - PTY

GSOPTY

Greensboro/H. Point

Tue 5/13

7:05 am-12:51 pm

1 stop6h 46m

Panama City Tocumen Intl

Sat 5/17

8:05 am-4:26 pm

1 stop7h 21m

$435

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Sun 5/4

7:48 pm-12:15 pm

2 stops17h 27m

Panama City Tocumen Intl

Sat 5/10

1:20 pm-12:16 pm

2 stops21h 56m

$440

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Wed 4/16

4:18 pm-7:46 pm

Nonstop4h 28m

Panama City Tocumen Intl

Wed 4/23

8:57 am-2:29 pm

Nonstop4h 32m

$441

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/19

Showing 1-10 of 39 results
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Best time to book a flight from North Carolina to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from North Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from North Carolina to Panama

Get recent, data-driven insights about flights from North Carolina to Panama including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from North Carolina to Panama?

Currently, October is the cheapest month in which you can book a flight from North Carolina to Panama (average of $478). Flying from North Carolina to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from NC to PA?

Find hourly flight availability from North Carolina to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 20, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from North Carolina to Panama as you normally would.

Rainfall in Panama by month

Plan your trip to Panama by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama when rainfall is around 0.4 in.

Temperature in Panama by month

Plan your trip to Panama by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated February 20, 2025.
Read through reviews of airlines operating flights from North Carolina to Panama, such as Delta, Copa Airlines and United Airlines. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
8,219 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Comfort

8.0

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta
8.0
Very good
8,219 reviews
Delta
8.0
Very good
8,219 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Comfort

8.0

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Copa Airlines
7.6
Good
1,510 reviews
Delta
8.0
Very good
8,219 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Comfort

8.0

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

United Airlines
7.4
Good
8,765 reviews
Delta
8.0
Very good
8,219 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Comfort

8.0

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,219 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Comfort

8.0

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Avianca
6.8
Okay
2,435 reviews
Delta
8.0
Very good
8,219 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Comfort

8.0

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from North Carolina to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from North Carolina to Panama one-way?

    For one-way options, check prices for Delta. According to our data, you can fly for as low as $147. Users have also found prices from $153 and $221 on American Airlines and United Airlines, respectively.

  • Can I find deals for flights from North Carolina to Panama that include hotel bookings?

    Yes. In addition to deals on North Carolina to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from North Carolina to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from North Carolina to Panama.

  • Can I find deals for business class flights from North Carolina to Panama?

    Yes. Cheapflights offers flight deals from North Carolina to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from North Carolina to Panama?

    Currently, October is the cheapest month in which you can book a flight from North Carolina to Panama (average of $478). Flying from North Carolina to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for North Carolina to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from North Carolina to Panama

Discover the top 4 airlines that operate flights from North Carolina to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$238Average$550FlexibilityNo cancel feeOn-timeN/A
Copa AirlinesCheapest$282Average$392FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$392Average$600FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$412Average$509FlexibilityNo cancel feeOn-time69%
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