Panama

$159+ Cheap flights from North Carolina to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/29. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — PTY
Jan 26 — Feb 21
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Cheap flight deals from North Carolina to Panama

Discover tips and strategies to find the most affordable flight options for your journey from North Carolina (USNC) to Panama (PA0). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 21, 2025.

Round-trip from

$365
(KAYAK)

One-way from

$159
(Delta)

Good round-trip deal

$291 or less

Good one-way deal

$158 or less
From North Carolina to Panama
One-way flight from North Carolina to Panama
Price to beat on a round-trip flight from North Carolina to Panama.
Price to beat on a one-way flight from North Carolina to Panama.

Find flight deals from North Carolina to Panama

Cheapest flights from North Carolina to Panama
Explore the most affordable flight options available from North Carolina to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2025.

This KAYAK deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/284:18 pmRDU - PTY
Nonstop4h 28mCopa Airlines
Wed 5/78:57 amPTY - RDU
Nonstop4h 32mCopa Airlines
Deal found 1/20$365
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/26:00 amRDU - PTY
1 stop9h 49mAmerican Airlines
Fri 2/74:40 pmPTY - RDU
1 stop16h 38mAmerican Airlines
Deal found 1/20$379
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/286:41 amORF - PTY
1 stop9h 08mAmerican Airlines
Thu 2/62:35 pmPTY - ORF
1 stop9h 17mAmerican Airlines
Deal found 1/20$383
This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/186:00 amORF - PTY
1 stop11h 07mUnited Airlines
Tue 2/254:40 pmPTY - ORF
1 stop31h 06mUnited Airlines
Deal found 1/20$392
This Avianca Connect deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/16:40 amCLT - PTY
2 stops14h 20mMultiple Airlines
Tue 3/43:19 amPTY - CLT
2 stops14h 25mMultiple Airlines
Deal found 1/21$411
This Mytrip deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/66:30 amAVL - PTY
2 stops18h 30mMultiple Airlines
Wed 3/123:19 amPTY - AVL
2 stops18h 25mMultiple Airlines
Deal found 1/20$417
This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/2510:20 amORF - PTY
1 stop9h 41mDelta
Sat 2/13:27 pmPTY - ORF
1 stop8h 32mDelta
Deal found 1/20$423
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/238:02 pmTYS - PTY
2 stops19h 30mAmerican Airlines
Wed 3/263:30 pmPTY - TYS
2 stops17h 32mAmerican Airlines
Deal found 1/20$442
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/227:43 pmAVL - PTY
2 stops17h 32mAmerican Airlines
Tue 4/291:15 pmPTY - AVL
2 stops22h 31mAmerican Airlines
Deal found 1/20$442
This Kiwi.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2012:04 pmRDU - PTY
1 stop7h 25mMultiple Airlines
Mon 2/249:33 pmPTY - RDU
1 stop13h 31mMultiple Airlines
Deal found 1/19$452
This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/66:30 amRDU - PTY
1 stop8h 49mUnited Airlines
Mon 9/810:00 amPTY - RDU
1 stop11h 06mUnited Airlines
Deal found 1/20$455
This Kissandfly.com deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kissandfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/137:05 amCLT - PTY
1 stop12h 57mLufthansa
Wed 3/193:40 pmPTY - CLT
1 stop18h 08mLufthansa
Deal found 1/21$455

Find flights from North Carolina to Panama within your budget

Customize your flight search to find flights from North Carolina to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2025.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Mon 4/28

4:18 pm-7:46 pm

Nonstop4h 28m

Panama City Tocumen Intl

Wed 5/7

8:57 am-2:29 pm

Nonstop4h 32m

$365

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Sun 2/2

6:00 am-3:49 pm

1 stop9h 49m

Panama City Tocumen Intl

Fri 2/7

4:40 pm-9:18 am

1 stop16h 38m

$379

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Tue 2/25

6:40 am-9:00 pm

2 stops14h 20m

Panama City Tocumen Intl

Mon 3/10

3:19 am-11:34 pm

2 stops19h 15m

$382

NorfolkPanama City

ORF - PTY

ORFPTY

Norfolk

Wed 3/19

6:10 am-6:38 pm

1 stop13h 28m

Panama City Tocumen Intl

Wed 3/26

11:35 am-11:59 pm

1 stop11h 24m

$383

NorfolkPanama City

ORF - PTY

ORFPTY

Norfolk

Thu 2/20

3:15 pm-1:30 pm

2 stops22h 15m

Panama City Tocumen Intl

Thu 2/27

2:30 pm-10:35 am

2 stops20h 05m

$416

AshevillePanama City

AVL - PTY

AVLPTY

Asheville Regional

Thu 3/6

6:30 am-1:00 am

2 stops18h 30m

Panama City Tocumen Intl

Wed 3/12

3:19 am-10:44 pm

2 stops18h 25m

$417

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Thu 4/3

7:01 pm-4:05 am

1 stop10h 04m

Panama City Tocumen Intl

Tue 4/8

10:00 am-9:59 pm

1 stop10h 59m

$437

KnoxvillePanama City

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

Sun 3/23

8:02 pm-2:32 pm

2 stops19h 30m

Panama City Tocumen Intl

Wed 3/26

3:30 pm-10:02 am

2 stops17h 32m

$442

AshevillePanama City

AVL - PTY

AVLPTY

Asheville Regional

Tue 4/22

7:43 pm-12:15 pm

2 stops17h 32m

Panama City Tocumen Intl

Tue 4/29

1:15 pm-12:46 pm

2 stops22h 31m

$442

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Thu 2/20

12:04 pm-7:29 pm

1 stop7h 25m

Panama City Tocumen Intl

Mon 2/24

9:33 pm-11:04 am

1 stop13h 31m

$452

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/21

Showing 1-10 of 49 results
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Best time to book a flight from North Carolina to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from North Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from North Carolina to Panama

Get recent, data-driven insights about flights from North Carolina to Panama including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from North Carolina to Panama?

Currently, October is the cheapest month in which you can book a flight from North Carolina to Panama (average of $478). Flying from North Carolina to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from NC to PA?

Find hourly flight availability from North Carolina to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 21, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from North Carolina to Panama as you normally would.

Rainfall in Panama by month

Plan your trip to Panama by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama when rainfall is around 0.4 in.

Temperature in Panama by month

Plan your trip to Panama by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated January 21, 2025.
Read through reviews of airlines operating flights from North Carolina to Panama, such as American Airlines, Avianca and United Airlines. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
8.0
Very good
8,521 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Crew

8.6

Entertainment

7.9

Comfort

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

8.0
Very good
8,521 reviews
8.0
Very good
8,521 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Crew

8.6

Entertainment

7.9

Comfort

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

7.7
Good
1,662 reviews
8.0
Very good
8,521 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Crew

8.6

Entertainment

7.9

Comfort

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

7.4
Good
8,985 reviews
8.0
Very good
8,521 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Crew

8.6

Entertainment

7.9

Comfort

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

7.2
Good
10,000 reviews
8.0
Very good
8,521 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Crew

8.6

Entertainment

7.9

Comfort

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

6.9
Okay
2,579 reviews
8.0
Very good
8,521 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Crew

8.6

Entertainment

7.9

Comfort

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from North Carolina to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What are the cheapest airlines to fly from North Carolina to Panama one-way?

    For one-way options, check prices for Delta. According to our data, you can fly for as low as $159. Users have also found prices from $215 and $421 on American Airlines and United Airlines, respectively.

  • Can I find deals for flights from North Carolina to Panama that include hotel bookings?

    Yes. In addition to deals on North Carolina to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from North Carolina to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from North Carolina to Panama.

  • Can I find deals for business class flights from North Carolina to Panama?

    Yes. Cheapflights offers flight deals from North Carolina to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from North Carolina to Panama?

    Currently, October is the cheapest month in which you can book a flight from North Carolina to Panama (average of $478). Flying from North Carolina to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for North Carolina to Panama

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from North Carolina to Panama

Discover the top 4 airlines that operate flights from North Carolina to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$238Average$562FlexibilityNo cancel feeOn-timeN/A
Copa AirlinesCheapest$282Average$392FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$394Average$512FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$405Average$594FlexibilityNo cancel feeOn-time71%
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