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$179+ Cheap flights from North Carolina to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/7. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — PTY
Apr 6 — Apr 131
Sun 4/6
Sun 4/13
1 adult, Economy
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Cheap flight deals from North Carolina to Panama

Keep the following information in mind while searching for North Carolina to Panama flight deals. Data was last updated April 1, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$374
(United Airlines)

One-way from

$179
(Delta)

Popular in

December

Cheapest in

September

Average price

$523

Good round-trip deal

$348 or less

Good one-way deal

$190 or less
Provider with most accurate pricing for Charlotte Douglas-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Charlotte Douglas-Panama City Tocumen Intl flights.
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From North Carolina to Panama
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One-way flight from North Carolina to Panama
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Highest demand for flights based on searches. 16% potential increase in price ($115 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($30 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Price to beat on a round-trip flight from North Carolina to Panama.
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Price to beat on a one-way flight from North Carolina to Panama.
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Find flight deals from North Carolina to Panama

Cheapest flights from North Carolina to Panama
Explore the most affordable flight options available from North Carolina to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 1, 2025.

This United Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/16:00 amORF - PTY
1 stop9h 14mUnited Airlines
Wed 4/23:20 pmPTY - ORF
2 stops22h 06mUnited Airlines
Deal found 3/31$364
This Delta deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/36:55 amORF - PTY
1 stop7h 00mDelta
Tue 5/62:20 pmPTY - ORF
1 stop8h 52mDelta
Deal found 3/31$377
This United Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/79:15 amTYS - PTY
1 stop7h 57mUnited Airlines
Mon 5/1210:00 amPTY - TYS
1 stop12h 46mUnited Airlines
Deal found 3/31$387
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/205:30 amGSO - PTY
1 stop8h 18mDelta
Thu 5/292:13 pmPTY - GSO
1 stop7h 18mDelta
Deal found 3/30$387
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/286:55 amTYS - PTY
1 stop6h 20mAmerican Airlines
Mon 5/51:20 pmPTY - TYS
2 stops20h 50mAmerican Airlines
Deal found 3/31$392
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/265:25 amRDU - PTY
1 stop8h 23mDelta
Fri 5/302:13 pmPTY - RDU
1 stop9h 06mDelta
Deal found 3/30$393
This Avianca Connect deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/86:00 amCLT - PTY
2 stops16h 10mMultiple Airlines
Thu 5/153:40 pmPTY - CLT
2 stops18h 23mMultiple Airlines
Deal found 3/31$395
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/275:40 amILM - PTY
1 stop7h 39mAmerican Airlines
Wed 6/41:20 pmPTY - ILM
1 stop8h 44mAmerican Airlines
Deal found 3/31$401
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/16:16 amORF - PTY
1 stop6h 59mAmerican Airlines
Wed 4/23:50 pmPTY - ORF
1 stop6h 58mAmerican Airlines
Deal found 3/31$409
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/246:36 pmGSO - PTY
2 stops18h 39mAmerican Airlines
Mon 4/281:15 pmPTY - GSO
1 stop9h 28mAmerican Airlines
Deal found 3/30$410
This United Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/226:13 amCLT - PTY
1 stop13h 24mUnited Airlines
Tue 4/297:55 amPTY - CLT
1 stop13h 04mUnited Airlines
Deal found 3/31$417
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/126:00 amCLT - PTY
1 stop7h 19mAmerican Airlines
Mon 5/191:20 pmPTY - CLT
2 stops16h 08mAmerican Airlines
Deal found 3/31$422

Cheapflights Fare Finder

Customize your flight search to find flights from North Carolina to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 1, 2025.
Use the filters below to find and compare flights from North Carolina to Panama that are best for you.

Fly from

North Carolina

Fly to

Panama

Route

Depart

Return

Price

NorfolkPanama City

ORF - PTY

ORFPTY

Norfolk

Thu 7/24

6:00 am-1:50 pm

1 stop8h 50m

Panama City Tocumen Intl

Mon 7/28

3:20 pm-10:27 pm

1 stop30h 07m

$374

NorfolkPanama City

ORF - PTY

ORFPTY

Norfolk

Sat 5/3

6:55 am-12:55 pm

1 stop7h 00m

Panama City Tocumen Intl

Tue 5/6

2:20 pm-12:12 am

1 stop8h 52m

$377

KnoxvillePanama City

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

Wed 5/7

9:15 am-4:12 pm

1 stop7h 57m

Panama City Tocumen Intl

Mon 5/12

10:00 am-11:46 pm

1 stop12h 46m

$387

GreensboroPanama City

GSO - PTY

GSOPTY

Greensboro/H. Point

Tue 5/20

5:30 am-12:48 pm

1 stop8h 18m

Panama City Tocumen Intl

Thu 5/29

2:13 pm-10:31 pm

1 stop7h 18m

$387

KnoxvillePanama City

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

Mon 4/28

6:55 am-12:15 pm

1 stop6h 20m

Panama City Tocumen Intl

Mon 5/5

1:20 pm-11:10 am

2 stops20h 50m

$392

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Mon 5/26

5:25 am-12:48 pm

1 stop8h 23m

Panama City Tocumen Intl

Fri 5/30

2:13 pm-12:19 am

1 stop9h 06m

$393

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Thu 5/8

6:00 am-9:10 pm

2 stops16h 10m

Panama City Tocumen Intl

Thu 5/15

3:40 pm-11:03 am

2 stops18h 23m

$395

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Tue 5/27

5:40 am-12:19 pm

1 stop7h 39m

Panama City Tocumen Intl

Wed 6/4

1:20 pm-11:04 pm

1 stop8h 44m

$401

GreensboroPanama City

GSO - PTY

GSOPTY

Greensboro/H. Point

Thu 4/24

6:36 pm-12:15 pm

2 stops18h 39m

Panama City Tocumen Intl

Mon 4/28

1:15 pm-11:43 pm

1 stop9h 28m

$410

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Tue 4/22

6:13 am-6:37 pm

1 stop13h 24m

Panama City Tocumen Intl

Tue 4/29

7:55 am-9:59 pm

1 stop13h 04m

$417

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/30

Showing 1-10 of 44 results
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Best time to book a flight from North Carolina to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from North Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from North Carolina to Panama

What is the cheapest month to book a flight from North Carolina to Panama?

Currently, October is the cheapest month in which you can book a flight from North Carolina to Panama (average of $478). Flying from North Carolina to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from NC to PA?

Find hourly flight availability from North Carolina to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 1, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from North Carolina to Panama as you normally would.

Rainfall in Panama by month

Plan your trip to Panama by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama when rainfall is around 0.4 in.

Temperature in Panama by month

Plan your trip to Panama by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated April 1, 2025.
Read through reviews of airlines operating flights from North Carolina to Panama, such as Delta, Copa Airlines and United Airlines. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,899 reviews

Comfort

8.0

Crew

8.5

Entertainment

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,899 reviews
Delta
8.0
Very good
7,899 reviews

Comfort

8.0

Crew

8.5

Entertainment

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.6
Good
1,400 reviews
Delta
8.0
Very good
7,899 reviews

Comfort

8.0

Crew

8.5

Entertainment

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,615 reviews
Delta
8.0
Very good
7,899 reviews

Comfort

8.0

Crew

8.5

Entertainment

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,899 reviews

Comfort

8.0

Crew

8.5

Entertainment

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Avianca
6.7
Okay
2,301 reviews
Delta
8.0
Very good
7,899 reviews

Comfort

8.0

Crew

8.5

Entertainment

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from North Carolina to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from North Carolina to Panama one-way?

    For one-way options, check prices for Delta. According to our data, you can fly for as low as $179. Users have also found prices from $179 and $225 on United Airlines and American Airlines, respectively.

  • Can I find deals for flights from North Carolina to Panama that include hotel bookings?

    Yes. In addition to deals on North Carolina to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from North Carolina to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from North Carolina to Panama.

  • Can I find deals for business class flights from North Carolina to Panama?

    Yes. Cheapflights offers flight deals from North Carolina to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from North Carolina to Panama?

    Currently, October is the cheapest month in which you can book a flight from North Carolina to Panama (average of $478). Flying from North Carolina to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for North Carolina to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from North Carolina to Panama

Discover the top 4 airlines that operate flights from North Carolina to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$281Average$550FlexibilityNo cancel feeOn-timeN/A
Copa AirlinesCheapest$282Average$397FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$284Average$590FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$412Average$515FlexibilityNo cancel feeOn-time69%
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