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$222+ Cheap flights from Missouri to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/19. Fares are subject to change and may not be available on all flights or dates of travel.
STL — PTY
Dec 23 — Dec 301
Mon 12/23
Mon 12/30
1 adult, Economy
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Cheap flight deals from Missouri to Panama

Discover tips and strategies to find the most affordable flight options for your journey from Missouri (USMO) to Panama (PA0). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 18, 2024.

Round-trip from

$468
(United)

One-way from

$222
(American Airlines)
From Missouri to Panama
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One-way flight from Missouri to Panama
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Find flight deals from Missouri to Panama

Cheapest flights from Missouri to Panama
Explore the most affordable flight options available from Missouri to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2024.

This United deal was found by Cheapflights users on 12/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/236:00 amSTL - PTY
1 stop7h 45mUnited Airlines
Tue 1/214:40 pmPTY - STL
1 stop18h 15mUnited Airlines
Deal found 12/18$544
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/246:00 amSTL - PTY
1 stop30h 20mAmerican Airlines
Tue 12/314:10 pmPTY - STL
1 stop8h 41mAmerican Airlines
Deal found 12/16$752
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/215:53 pmMCI - PTY
1 stop20h 27mAmerican Airlines
Mon 12/234:10 pmPTY - MCI
1 stop9h 08mAmerican Airlines
Deal found 12/17$848
This Delta deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/245:17 pmSTL - PTY
1 stop19h 38mDelta
Sat 12/288:10 amPTY - STL
1 stop14h 49mDelta
Deal found 12/16$889
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/246:00 amSTL - PTY
1 stop12h 22mMultiple Airlines
Sat 12/286:25 pmPTY - STL
2 stops21h 56mMultiple Airlines
Deal found 12/16$1,063
This Mytrip deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/217:11 pmMCI - PTY
3 stops24h 49mMultiple Airlines
Sun 12/223:19 amPTY - MCI
2 stops15h 46mMultiple Airlines
Deal found 12/17$1,180

Find flights from Missouri to Panama within your budget

Customize your flight search to find flights from Missouri to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2024.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Wed 2/12

6:15 am-2:45 pm

1 stop7h 30m

Panama City Tocumen Intl

Thu 2/20

4:40 pm-9:51 am

1 stop18h 11m

$468

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Wed 2/12

6:29 pm-3:50 pm

2 stops20h 21m

Panama City Tocumen Intl

Thu 2/20

4:40 pm-11:40 pm

1 stop8h 00m

$473

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Mon 4/14

6:00 am-12:51 pm

1 stop6h 51m

Panama City Tocumen Intl

Sat 4/19

8:05 am-3:58 pm

1 stop7h 53m

$488

Kansas CityPanama City

MCI - PTY

MCIPTY

Kansas City

Wed 3/26

7:40 am-6:38 pm

2 stops10h 58m

Panama City Tocumen Intl

Mon 3/31

10:00 am-10:42 pm

1 stop12h 42m

$500

Kansas CityPanama City

MCI - PTY

MCIPTY

Kansas City

Tue 6/3

6:42 pm-12:51 pm

1 stop18h 09m

Panama City Tocumen Intl

Tue 6/17

2:13 pm-12:28 pm

1 stop22h 15m

$509

Kansas CityPanama City

MCI - PTY

MCIPTY

Kansas City

Sat 3/29

5:01 pm-2:11 pm

2 stops21h 10m

Panama City Tocumen Intl

Sun 4/13

1:55 pm-11:40 am

2 stops21h 45m

$624

Kansas CityPanama City

MCI - PTY

MCIPTY

Kansas City

Sun 1/12

7:54 pm-12:20 am

3 stops27h 26m

Panama City Tocumen Intl

Sun 2/2

3:34 pm-2:55 pm

2 stops24h 21m

$722

SpringfieldPanama City

SGF - PTY

SGFPTY

Springfield-Branson

Fri 1/3

6:35 am-5:07 pm

1 stop9h 32m

Panama City Tocumen Intl

Wed 1/8

4:40 pm-1:59 pm

1 stop22h 19m

$731

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Thu 1/16

4:28 pm-9:00 pm

3 stops27h 32m

Panama City Tocumen Intl

Wed 1/22

3:19 am-11:45 am

3 stops33h 26m

$740

SpringfieldPanama City

SGF - PTY

SGFPTY

Springfield-Branson

Fri 1/3

7:17 pm-3:20 pm

2 stops19h 03m

Panama City Tocumen Intl

Wed 1/8

4:40 pm-11:10 am

2 stops19h 30m

$863

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/18

Showing 1-10 of 17 results
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Best time to book a flight from Missouri to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Missouri to Panama

Get recent, data-driven insights about flights from Missouri to Panama including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Missouri to Panama?

Currently, October is the cheapest month in which you can book a flight from Missouri to Panama (average of $478). Flying from Missouri to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to PA?

Find hourly flight availability from Missouri to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2024.

When flying from Missouri to Panama, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Panama by month

Plan your trip to Panama by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama when rainfall is around 0.4 in.

Temperature in Panama by month

Plan your trip to Panama by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated December 18, 2024.
Peruse reviews from past customers who have flown with United Airlines, Delta and American Airlines from Missouri to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
8,604 reviews

Entertainment

7.9

Boarding

8.2

Crew

8.6

Comfort

7.9

Food

7.3

Overall

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta
8.0
Very good
8,604 reviews
Delta
8.0
Very good
8,604 reviews

Entertainment

7.9

Boarding

8.2

Crew

8.6

Comfort

7.9

Food

7.3

Overall

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

United Airlines
7.4
Good
9,055 reviews
Delta
8.0
Very good
8,604 reviews

Entertainment

7.9

Boarding

8.2

Crew

8.6

Comfort

7.9

Food

7.3

Overall

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,604 reviews

Entertainment

7.9

Boarding

8.2

Crew

8.6

Comfort

7.9

Food

7.3

Overall

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Avianca
7.0
Good
2,667 reviews
Delta
8.0
Very good
8,604 reviews

Entertainment

7.9

Boarding

8.2

Crew

8.6

Comfort

7.9

Food

7.3

Overall

8.0

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Missouri to Panama one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $222. However, be on the lookout for offers from United Airlines and Delta, as they are both options that can get you from Missouri to Panama for a low price.

  • Can I find deals for flights from Missouri to Panama that include hotel bookings?

    Yes. In addition to deals on Missouri to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Panama.

  • Can I find deals for business class flights from Missouri to Panama?

    Yes. Cheapflights offers flight deals from Missouri to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Panama?

    Currently, October is the cheapest month in which you can book a flight from Missouri to Panama (average of $478). Flying from Missouri to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Missouri to Panama

Discover the top 3 airlines that operate flights from Missouri to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2024.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$351Average$530FlexibilityNo cancel feeOn-time69%
DeltaCheapest$391Average$611FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$414Average$575FlexibilityNo cancel feeOn-time71%
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