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$469+ Cheap flights from Mississippi to Panama

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/26. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — PTY
Feb 25 — Mar 41
Tue 2/25
Tue 3/4
1 adult, Economy
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Cheap flight deals from Mississippi to Panama

Keep the following information in mind while searching for Mississippi to Panama flight deals. Data was last updated February 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$469
(Delta)
Provider with most accurate pricing for Jackson-Evers Intl-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Jackson-Evers Intl-Panama City Tocumen Intl flights.
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From Mississippi to Panama
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Find flight deals from Mississippi to Panama

Cheapest flights from Mississippi to Panama
Explore the most affordable flight options available from Mississippi to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/266:00 amMEM - PTY
1 stop6h 51mDelta
Tue 6/102:13 pmPTY - MEM
1 stop8h 35mDelta
Deal found 2/19$469
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/265:52 amMEM - PTY
1 stop8h 40mAmerican Airlines
Mon 3/313:30 pmPTY - MEM
2 stops22h 24mAmerican Airlines
Deal found 2/20$478
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/43:36 pmJAN - PTY
2 stops20h 39mAmerican Airlines
Tue 4/81:15 pmPTY - JAN
2 stops20h 27mAmerican Airlines
Deal found 2/20$480
This United deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/266:30 amMEM - PTY
1 stop7h 15mUnited Airlines
Mon 3/317:55 amPTY - MEM
1 stop25h 51mUnited Airlines
Deal found 2/20$481
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/411:59 amJAN - PTY
1 stop6h 38mUnited Airlines
Tue 4/83:20 pmPTY - JAN
1 stop19h 59mUnited Airlines
Deal found 2/20$503
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/216:22 pmBTR - PTY
2 stops17h 53mAmerican Airlines
Tue 4/291:15 pmPTY - BTR
2 stops10h 47mAmerican Airlines
Deal found 2/19$516
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1312:01 pmBTR - PTY
1 stop28h 11mUnited Airlines
Wed 4/167:55 amPTY - BTR
1 stop11h 28mUnited Airlines
Deal found 2/20$528
This Avianca Connect deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/68:57 amMEM - PTY
2 stops12h 13mMultiple Airlines
Sat 4/123:20 amPTY - MEM
2 stops14h 36mMultiple Airlines
Deal found 2/20$607

Find flights from Mississippi to Panama within your budget

Customize your flight search to find flights from Mississippi to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.

Fly from

Mississippi

Fly to

Panama

Route

Depart

Return

Price

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Mon 5/26

6:00 am-12:51 pm

1 stop6h 51m

Panama City Tocumen Intl

Tue 6/10

2:13 pm-10:48 pm

1 stop8h 35m

$469

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Wed 3/26

6:52 pm-12:15 pm

2 stops17h 23m

Panama City Tocumen Intl

Mon 3/31

3:30 pm-11:51 am

2 stops20h 21m

$478

JacksonPanama City

JAN - PTY

JANPTY

Jackson-Evers Intl

Fri 4/4

3:36 pm-12:15 pm

2 stops20h 39m

Panama City Tocumen Intl

Tue 4/8

1:15 pm-9:42 am

2 stops20h 27m

$480

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Wed 3/26

6:30 am-1:45 pm

1 stop7h 15m

Panama City Tocumen Intl

Mon 3/31

7:55 am-9:46 am

1 stop25h 51m

$481

JacksonPanama City

JAN - PTY

JANPTY

Jackson-Evers Intl

Fri 4/4

11:59 am-6:37 pm

1 stop6h 38m

Panama City Tocumen Intl

Tue 4/8

3:20 pm-11:19 am

1 stop19h 59m

$503

Baton RougePanama City

BTR - PTY

BTRPTY

Baton Rouge Ryan

Mon 4/21

6:22 pm-12:15 pm

2 stops17h 53m

Panama City Tocumen Intl

Tue 4/29

1:15 pm-12:02 am

2 stops10h 47m

$516

Baton RougePanama City

BTR - PTY

BTRPTY

Baton Rouge Ryan

Sun 4/13

12:01 pm-4:12 pm

1 stop28h 11m

Panama City Tocumen Intl

Wed 4/16

7:55 am-7:23 pm

1 stop11h 28m

$528

MemphisPanama City

MEM - PTY

MEMPTY

Memphis

Sun 4/6

8:57 am-9:10 pm

2 stops12h 13m

Panama City Tocumen Intl

Sat 4/12

3:20 am-5:56 pm

2 stops14h 36m

$607

JacksonPanama City

JAN - PTY

JANPTY

Jackson-Evers Intl

Thu 3/13

7:00 am-4:07 pm

1 stop9h 07m

$485

JacksonPanama City

JAN - PTY

JANPTY

Jackson-Evers Intl

Thu 3/13

5:05 am-2:32 pm

2 stops9h 27m

$816

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/18

Best time to book a flight from Mississippi to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Mississippi to Panama

Get recent, data-driven insights about flights from Mississippi to Panama including ideal travel times, pricing trends, and more.

Rainfall in Panama by month

Plan your trip to Panama by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama when rainfall is around 0.4 in.

Temperature in Panama by month

Plan your trip to Panama by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated February 20, 2025.
Get a feel of what it's like to fly with Delta, United Airlines and American Airlines from Mississippi to Panama by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
8,219 reviews

Food

7.3

Boarding

8.2

Comfort

8.0

Overall

8.0

Crew

8.5

Entertainment

7.9

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta
8.0
Very good
8,219 reviews
Delta
8.0
Very good
8,219 reviews

Food

7.3

Boarding

8.2

Comfort

8.0

Overall

8.0

Crew

8.5

Entertainment

7.9

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

United Airlines
7.4
Good
8,765 reviews
Delta
8.0
Very good
8,219 reviews

Food

7.3

Boarding

8.2

Comfort

8.0

Overall

8.0

Crew

8.5

Entertainment

7.9

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,219 reviews

Food

7.3

Boarding

8.2

Comfort

8.0

Overall

8.0

Crew

8.5

Entertainment

7.9

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • Can I find deals for flights from Mississippi to Panama that include hotel bookings?

    Yes. In addition to deals on Mississippi to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Panama.

  • Can I find deals for business class flights from Mississippi to Panama?

    Yes. Cheapflights offers flight deals from Mississippi to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to Panama?

    Currently, October is the cheapest month in which you can book a flight from Mississippi to Panama (average of $478). Flying from Mississippi to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Mississippi to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Mississippi to Panama

Discover the top 2 airlines that operate flights from Mississippi to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$397Average$417FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$413Average$514FlexibilityNo cancel feeOn-time69%
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