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$169+ Cheap flights from Louisville (SDF) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/28. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — PTY
Apr 22 — Apr 291
Tue 4/22
Tue 4/29
1 adult, Economy
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Cheap flight deals from Louisville to Panama

Keep the following information in mind while searching for Louisville to Panama flight deals. Data was last updated April 17, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$403
(United Airlines)

One-way from

$169
(Delta)

Popular in

December

Cheapest in

October

Average price

$477
Provider with most accurate pricing for Louisville Intl-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Louisville Intl-Panama City Tocumen Intl flights.
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From Louisville Intl to Panama
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One-way flight from Louisville Intl to Panama
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Highest demand for flights based on searches. 13% potential increase in price ($76 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($19 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Louisville to Panama

Cheapest flights from Louisville to Panama
Explore the most affordable flight options available from Louisville to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.

This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/289:25 amSDF - PTY
1 stop10h 12mUnited Airlines
Mon 5/57:55 amPTY - SDF
1 stop12h 45mUnited Airlines
Deal found 4/16$403
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/286:15 amSDF - PTY
1 stop7h 04mAmerican Airlines
Mon 6/163:20 pmPTY - SDF
1 stop7h 37mAmerican Airlines
Deal found 4/17$414
This Avianca Connect deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/285:45 amSDF - PTY
2 stops16h 25mMultiple Airlines
Sun 5/43:20 amPTY - SDF
2 stops14h 11mMultiple Airlines
Deal found 4/16$437
This Delta deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/317:05 amSDF - PTY
1 stop6h 43mDelta
Sat 6/72:13 pmPTY - SDF
1 stop8h 52mDelta
Deal found 4/15$443

Cheapflights Fare Finder

Customize your flight search to find flights from Louisville to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
Use the filters below to find and compare flights from Louisville to Panama that are best for you.

Fly from

Louisville

Fly to

Panama

Route

Depart

Return

Price

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Mon 4/28

9:25 am-4:12 pm

1 stop7h 47m

Panama City Tocumen Intl

Mon 5/5

7:55 am-8:00 pm

1 stop11h 05m

$403

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Wed 5/28

6:15 am-12:19 pm

1 stop7h 04m

Panama City Tocumen Intl

Mon 6/16

3:20 pm-11:57 pm

1 stop7h 37m

$414

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Sat 5/3

7:05 am-12:55 pm

1 stop6h 50m

Panama City Tocumen Intl

Thu 5/8

2:13 pm-10:43 pm

1 stop7h 30m

$423

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Mon 4/28

5:45 am-12:10 am

2 stops19h 25m

Panama City Tocumen Intl

Sun 5/4

3:20 am-6:31 pm

2 stops14h 11m

$433

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Mon 4/28

6:00 am-12:55 pm

1 stop7h 55m

$169

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Thu 5/15

11:23 am-7:50 pm

3 stops33h 27m

$233

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Thu 5/15

7:00 am-6:37 pm

1 stop12h 37m

$247

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/17

Best time to book a flight from Louisville to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Louisville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Louisville to Panama

What is the cheapest month to book a flight from Louisville to Panama?

Currently, October is the cheapest month in which you can book a flight from Louisville to Panama (average of $478). Flying from Louisville to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SDF to PA?

Find hourly flight availability from Louisville to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 17, 2025.

When flying from Louisville to Panama, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Panama by month

Plan your trip to Panama by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama when rainfall is around 0.4 in.

Temperature in Panama by month

Plan your trip to Panama by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated April 17, 2025.
Delta
8.0
Very good
7,917 reviews

Entertainment

7.9

Boarding

8.2

Crew

8.5

Overall

8.0

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,917 reviews
Delta
8.0
Very good
7,917 reviews

Entertainment

7.9

Boarding

8.2

Crew

8.5

Overall

8.0

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,667 reviews
Delta
8.0
Very good
7,917 reviews

Entertainment

7.9

Boarding

8.2

Crew

8.5

Overall

8.0

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,917 reviews

Entertainment

7.9

Boarding

8.2

Crew

8.5

Overall

8.0

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Louisville to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Louisville to Panama?

    Louisville Intl (SDF) is the airport you will fly out of if you book a flight from Louisville to Panama. It is only a 5.3 mi journey to Louisville Intl (SDF) from Louisville’s city center.

  • Can I find deals for flights from Louisville to Panama that include hotel bookings?

    Yes. In addition to deals on Louisville to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Louisville to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisville to Panama.

  • Can I find deals for business class flights from Louisville to Panama?

    Yes. Cheapflights offers flight deals from Louisville to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Louisville to Panama?

    Currently, October is the cheapest month in which you can book a flight from Louisville to Panama (average of $478). Flying from Louisville to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Louisville to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Louisville to Panama

Discover the top 3 airlines that operate flights from Louisville to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$311Average$487FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$338Average$500FlexibilityNo cancel feeOn-time71%
DeltaCheapest$361Average$483FlexibilityNo cancel feeOn-timeN/A

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