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$364+ Cheap flights from Louisville (SDF) to Panama

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/26. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — PTY
Apr 2 — Apr 91
Wed 4/2
Wed 4/9
1 adult, Economy
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Cheap flight deals from Louisville to Panama

Keep the following information in mind while searching for Louisville to Panama flight deals. Data was last updated March 28, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$390
(American Airlines)

Popular in

June

Cheapest in

October

Average price

$537
Provider with most accurate pricing for Louisville Intl-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Louisville Intl-Panama City Tocumen Intl flights.
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From Louisville Intl to Panama
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High demand for flights, 0% potential price rise
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Cheapest flight prices on average. 3% potential price decrease ($18 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Find flight deals from Louisville to Panama

Cheapest flights from Louisville to Panama
Explore the most affordable flight options available from Louisville to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 28, 2025.

This United Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/265:45 pmSDF - PTY
2 stops21h 00mUnited Airlines
Fri 3/283:40 pmPTY - SDF
1 stop20h 38mUnited Airlines
Deal found 3/26$364
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/286:15 amSDF - PTY
1 stop7h 04mAmerican Airlines
Mon 6/161:50 pmPTY - SDF
1 stop9h 07mAmerican Airlines
Deal found 3/27$390
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/17:09 amSDF - PTY
1 stop6h 46mDelta
Fri 4/42:23 pmPTY - SDF
1 stop8h 35mDelta
Deal found 3/26$412
This Mytrip deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/16:00 amSDF - PTY
2 stops19h 10mMultiple Airlines
Thu 4/33:20 amPTY - SDF
3 stops31h 43mMultiple Airlines
Deal found 3/26$627

Cheapflights Fare Finder

Customize your flight search to find flights from Louisville to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
Use the filters below to find and compare flights from Louisville to Panama that are best for you.

Fly from

Louisville

Fly to

Panama

Route

Depart

Return

Price

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Wed 5/28

6:15 am-12:19 pm

1 stop7h 04m

Panama City Tocumen Intl

Mon 6/16

1:50 pm-11:57 pm

1 stop9h 07m

$390

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Wed 5/28

7:00 am-7:31 pm

2 stops13h 31m

Panama City Tocumen Intl

Mon 6/16

3:20 pm-9:33 am

2 stops17h 13m

$395

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Tue 4/1

7:09 am-12:55 pm

1 stop6h 46m

Panama City Tocumen Intl

Fri 4/4

2:23 pm-11:58 pm

1 stop8h 35m

$412

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Tue 4/1

6:00 am-12:10 am

2 stops19h 10m

Panama City Tocumen Intl

Thu 4/3

3:20 am-12:03 pm

3 stops31h 43m

$627

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/27

Best time to book a flight from Louisville to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Louisville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Louisville to Panama

What is the cheapest month to book a flight from Louisville to Panama?

Currently, October is the cheapest month in which you can book a flight from Louisville to Panama (average of $478). Flying from Louisville to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SDF to PA?

Find hourly flight availability from Louisville to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 28, 2025.

When flying from Louisville to Panama, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Panama by month

Plan your trip to Panama by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama when rainfall is around 0.4 in.

Temperature in Panama by month

Plan your trip to Panama by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated March 28, 2025.
Read reviews from past customers who have flown Delta, United Airlines and American Airlines from Louisville to Panama. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,896 reviews

Entertainment

7.9

Overall

8.0

Food

7.3

Comfort

8.0

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,896 reviews
Delta
8.0
Very good
7,896 reviews

Entertainment

7.9

Overall

8.0

Food

7.3

Comfort

8.0

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,603 reviews
Delta
8.0
Very good
7,896 reviews

Entertainment

7.9

Overall

8.0

Food

7.3

Comfort

8.0

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,896 reviews

Entertainment

7.9

Overall

8.0

Food

7.3

Comfort

8.0

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Louisville to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Louisville to Panama?

    Louisville Intl (SDF) is the airport you will fly out of if you book a flight from Louisville to Panama. It is only a 5.3 mi journey to Louisville Intl (SDF) from Louisville’s city center.

  • Can I find deals for flights from Louisville to Panama that include hotel bookings?

    Yes. In addition to deals on Louisville to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Louisville to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisville to Panama.

  • Can I find deals for business class flights from Louisville to Panama?

    Yes. Cheapflights offers flight deals from Louisville to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Louisville to Panama?

    Currently, October is the cheapest month in which you can book a flight from Louisville to Panama (average of $478). Flying from Louisville to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Louisville to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Louisville to Panama

Discover the top 3 airlines that operate flights from Louisville to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$306Average$487FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$326Average$489FlexibilityNo cancel feeOn-time71%
DeltaCheapest$361Average$483FlexibilityNo cancel feeOn-timeN/A
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