$442+ Cheap flights from Knoxville (TYS) to Panama
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/23. Fares are subject to change and may not be available on all flights or dates of travel.
Find cheap flights from Knoxville to Panama with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Panama
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Panama (PA0). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 21, 2025.
Round-trip from | $442 (American Airlines) |
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Find flight deals from Knoxville to Panama
Cheapest flights from Knoxville to PanamaExplore the most affordable flight options available from Knoxville to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2025.
Explore the most affordable flight options available from Knoxville to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2025.
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Kiwi.com deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This SmartFares deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Find flights from Knoxville to Panama within your budget
Customize your flight search to find flights from Knoxville to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2025.
Fly from
Fly to
Route
Depart
Return
Price
KnoxvillePanama City
TYS - PTY
TYSPTY
Knoxville McGhee Tyson
Sun 3/23
8:02 pm-2:32 pm
2 stops19h 30m
Panama City Tocumen Intl
Wed 3/26
3:30 pm-10:02 am
2 stops17h 32m
KnoxvillePanama City
TYS - PTY
TYSPTY
Knoxville McGhee Tyson
Tue 3/4
7:05 am-5:07 pm
1 stop10h 02m
Panama City Tocumen Intl
Tue 3/11
3:40 pm-8:02 pm
1 stop27h 22m
KnoxvillePanama City
TYS - PTY
TYSPTY
Knoxville McGhee Tyson
Sat 3/1
8:00 am-8:19 pm
1 stop12h 19m
Panama City Tocumen Intl
Sat 3/15
12:03 pm-9:46 pm
1 stop8h 43m
KnoxvillePanama City
TYS - PTY
TYSPTY
Knoxville McGhee Tyson
Tue 3/4
7:25 pm-4:30 pm
2 stops21h 05m
Panama City Tocumen Intl
Mon 3/10
3:19 am-10:45 pm
2 stops18h 26m
Best time to book a flight from Knoxville to Panama
Have a flexible travel schedule? Discover the best time to fly to Panama from Knoxville with our price prediction graph.
Travel insights for flights from Knoxville to Panama
Get recent, data-driven insights about flights from Knoxville to Panama including ideal travel times, pricing trends, and more.
What is the cheapest month to book a flight from Knoxville to Panama?
Currently, October is the cheapest month in which you can book a flight from Knoxville to Panama (average of $478). Flying from Knoxville to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from TYS to PA?
Find hourly flight availability from Knoxville to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 21, 2025.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Knoxville to Panama as you normally would.
Rainfall in Panama by month
Plan your trip to Panama by taking into account the average rainfall totals by month.
In terms of precipitation, rainfall in Panama ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama when rainfall is around 0.4 in.
Temperature in Panama by month
Plan your trip to Panama by taking into account the average temperature totals by month.
If weather is an important factor for your trip to Panama, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).
Reviews of airlines servicing Panama
Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated January 21, 2025.
Crew
Overall
Food
Boarding
Comfort
Entertainment
Reviews
United Airlines flights seem to always use a bus to/from the boarding gate to the plane. Can they not get their own gate? This time there was no lift when leaving the plane and people in wheelchairs somehow had to climb down the steps to the ground to get to the bus. I udon’t know how some managed that!
Crew
Overall
Food
Boarding
Comfort
Entertainment
Reviews
United Airlines flights seem to always use a bus to/from the boarding gate to the plane. Can they not get their own gate? This time there was no lift when leaving the plane and people in wheelchairs somehow had to climb down the steps to the ground to get to the bus. I udon’t know how some managed that!
Crew
Overall
Food
Boarding
Comfort
Entertainment
Reviews
United Airlines flights seem to always use a bus to/from the boarding gate to the plane. Can they not get their own gate? This time there was no lift when leaving the plane and people in wheelchairs somehow had to climb down the steps to the ground to get to the bus. I udon’t know how some managed that!
Crew
Overall
Food
Boarding
Comfort
Entertainment
Reviews
United Airlines flights seem to always use a bus to/from the boarding gate to the plane. Can they not get their own gate? This time there was no lift when leaving the plane and people in wheelchairs somehow had to climb down the steps to the ground to get to the bus. I udon’t know how some managed that!
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Knoxville to Panama
See prices for flight routes from nearby airports that may be better suited for you.
Top 3 airlines flying from Knoxville to Panama
Discover the top 3 airlines that operate flights from Knoxville to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$281 | Average$754 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$368 | Average$625 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$427 | Average$548 | FlexibilityNo cancel fee | On-timeN/A |