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$222+ Cheap flights from Knoxville (TYS) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/8. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — PTY
Dec 26 — Jan 21
Thu 12/26
Thu 1/2
1 adult, Economy
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Cheap flight deals from Knoxville to Panama

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Panama (PA0). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 21, 2024.

Round-trip from

$456
(United)

One-way from

$222
(American Airlines)
From Knoxville McGhee Tyson to Panama
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One-way flight from Knoxville McGhee Tyson to Panama
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Find flight deals from Knoxville to Panama

Cheapest flights from Knoxville to Panama
Explore the most affordable flight options available from Knoxville to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 21, 2024.

This United Airlines deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/257:00 amTYS - PTY
1 stop12h 38mUnited Airlines
Mon 12/304:40 pmPTY - TYS
1 stop27h 20mUnited Airlines
Deal found 12/20$517
This American Airlines deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/226:01 pmTYS - PTY
2 stops19h 19mAmerican Airlines
Sat 12/284:10 pmPTY - TYS
1 stop8h 02mAmerican Airlines
Deal found 12/20$683
This Mytrip deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/318:55 amTYS - PTY
2 stops24h 45mMultiple Airlines
Fri 1/36:30 pmPTY - TYS
2 stops27h 38mMultiple Airlines
Deal found 12/20$849
This Delta deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/206:36 pmTYS - PTY
1 stop25h 27mDelta
Mon 12/303:20 pmPTY - TYS
1 stop19h 39mDelta
Deal found 12/20$1,555
This Avianca deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/227:24 pmTYS - PTY
2 stops15h 01mAvianca
Fri 12/273:19 amPTY - TYS
2 stops16h 03mAvianca
Deal found 12/20$2,422

Find flights from Knoxville to Panama within your budget

Customize your flight search to find flights from Knoxville to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 21, 2024.

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Route

Depart

Return

Price

KnoxvillePanama City

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

Wed 2/5

9:10 am-5:07 pm

1 stop7h 57m

Panama City Tocumen Intl

Tue 2/11

11:35 am-11:46 pm

1 stop12h 11m

$456

KnoxvillePanama City

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

Wed 2/5

8:05 pm-3:49 pm

2 stops19h 44m

Panama City Tocumen Intl

Tue 2/11

4:40 pm-11:14 am

2 stops18h 34m

$481

KnoxvillePanama City

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

Fri 1/17

12:00 pm-4:54 pm

2 stops28h 54m

Panama City Tocumen Intl

Mon 3/17

12:03 pm-9:21 pm

1 stop8h 18m

$764

KnoxvillePanama City

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

Thu 1/9

6:20 am-1:00 am

2 stops18h 40m

Panama City Tocumen Intl

Mon 1/20

3:19 am-10:41 pm

2 stops19h 22m

$1,090

KnoxvillePanama City

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

Wed 1/8

6:00 am-3:49 pm

2 stops9h 49m

$222

KnoxvillePanama City

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

Wed 1/8

4:55 pm-7:38 pm

1 stop26h 43m

$236

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/20

Best time to book a flight from Knoxville to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Knoxville to Panama

Get recent, data-driven insights about flights from Knoxville to Panama including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Knoxville to Panama?

Currently, October is the cheapest month in which you can book a flight from Knoxville to Panama (average of $478). Flying from Knoxville to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to PA?

Find hourly flight availability from Knoxville to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 21, 2024.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Knoxville to Panama as you normally would.

Rainfall in Panama by month

Plan your trip to Panama by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama when rainfall is around 0.4 in.

Temperature in Panama by month

Plan your trip to Panama by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated December 21, 2024.
United Airlines
7.4
Good
9,039 reviews

Crew

8.1

Overall

7.4

Boarding

7.7

Food

6.7

Entertainment

7.1

Comfort

7.3

Reviews

1 / 10

Good boarding process. (Nice to be able to buy Group 2 boarding option.) Plane was clean. Tried to avoid full flight by flying on Saturday, but plane was full anyway. Gate area in Houston should have charging options. Should be a lounge for people with American Express Platinum Card in Houston Airport.

United Airlines
7.4
Good
9,039 reviews
United Airlines
7.4
Good
9,039 reviews

Crew

8.1

Overall

7.4

Boarding

7.7

Food

6.7

Entertainment

7.1

Comfort

7.3

Reviews

1 / 10

Good boarding process. (Nice to be able to buy Group 2 boarding option.) Plane was clean. Tried to avoid full flight by flying on Saturday, but plane was full anyway. Gate area in Houston should have charging options. Should be a lounge for people with American Express Platinum Card in Houston Airport.

American Airlines
7.2
Good
10,000 reviews
United Airlines
7.4
Good
9,039 reviews

Crew

8.1

Overall

7.4

Boarding

7.7

Food

6.7

Entertainment

7.1

Comfort

7.3

Reviews

1 / 10

Good boarding process. (Nice to be able to buy Group 2 boarding option.) Plane was clean. Tried to avoid full flight by flying on Saturday, but plane was full anyway. Gate area in Houston should have charging options. Should be a lounge for people with American Express Platinum Card in Houston Airport.

Avianca
7.0
Good
2,654 reviews
United Airlines
7.4
Good
9,039 reviews

Crew

8.1

Overall

7.4

Boarding

7.7

Food

6.7

Entertainment

7.1

Comfort

7.3

Reviews

1 / 10

Good boarding process. (Nice to be able to buy Group 2 boarding option.) Plane was clean. Tried to avoid full flight by flying on Saturday, but plane was full anyway. Gate area in Houston should have charging options. Should be a lounge for people with American Express Platinum Card in Houston Airport.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Panama?

    For a flight from Knoxville to Panama, you will be flying from McGhee Tyson. Knoxville McGhee Tyson (TYS) is just 11.3 mi from the center of the city.

  • Can I find deals for flights from Knoxville to Panama that include hotel bookings?

    Yes. In addition to deals on Knoxville to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Panama.

  • Can I find deals for business class flights from Knoxville to Panama?

    Yes. Cheapflights offers flight deals from Knoxville to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Panama?

    Currently, October is the cheapest month in which you can book a flight from Knoxville to Panama (average of $478). Flying from Knoxville to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Knoxville to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Knoxville to Panama

Discover the top 3 airlines that operate flights from Knoxville to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 21, 2024.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$281Average$650FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$299Average$621FlexibilityNo cancel feeOn-time71%
DeltaCheapest$427Average$548FlexibilityNo cancel feeOn-timeN/A
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