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$127+ Cheap flights from Key Largo, FL to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/17. Fares are subject to change and may not be available on all flights or dates of travel.
MIA — PTY
feb. 25 — mar. 41
mar. 2/25
mar. 3/4
1 adult, Economy
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Cheap flight deals from Key Largo to Panama

Keep the following information in mind while searching for Key Largo to Panama flight deals. Data was last updated febrero 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$286
(eDestinos)

One-way from

$127
(Cheapflightsfares)

Popular in

December

Cheapest in

April

Average price

$313
Provider with most accurate pricing for Miami-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Miami-Panama City Tocumen Intl flights.
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From Key Largo to Panama
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One-way flight from Key Largo to Panama
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Highest demand for flights based on searches. 7% potential increase in price ($29 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in February 2025
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Find flight deals from Key Largo to Panama

Cheapest flights from Key Largo to Panama
Explore the most affordable flight options available from Key Largo to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on febrero 20, 2025.

This eDestinos deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 4/174:57 pmMIA - PTY
1 stop22h 17mUnited Airlines
dom. 5/257:55 amPTY - MIA
1 stop13h 50mUnited Airlines
Deal found 2/20$286
This Cheapflightsfares deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 3/137:20 pmMIA - PTY
1 stop6h 40mAvianca
lun. 3/249:55 pmPTY - MIA
1 stop11h 05mAvianca
Deal found 2/19$290
This Booking.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 4/68:30 amMIA - PTY
Nonstop3h 10mCopa Airlines
dom. 4/1310:25 amPTY - MIA
Nonstop3h 15mCopa Airlines
Deal found 2/20$293
This KAYAK deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 3/306:18 amMIA - DAV
1 stop12h 08mCopa Airlines
sáb. 4/56:18 pmDAV - MIA
1 stop6h 20mCopa Airlines
Deal found 2/20$308
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 3/2112:17 pmMIA - PTY
Nonstop3h 15mAmerican Airlines
mié. 3/263:30 pmPTY - MIA
Nonstop3h 05mAmerican Airlines
Deal found 2/20$315
This Booking.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 4/2512:20 pmMIA - PTY
Nonstop3h 10mMultiple Airlines
vie. 5/95:25 pmPTY - MIA
1 stop9h 35mMultiple Airlines
Deal found 2/19$330
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 3/26:00 amMIA - PTY
1 stop8h 02mDelta
mié. 3/53:27 pmPTY - MIA
1 stop9h 24mDelta
Deal found 2/20$346
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 3/207:20 pmMIA - DAV
2 stops20h 40mMultiple Airlines
jue. 3/279:41 amDAV - MIA
1 stop6h 03mMultiple Airlines
Deal found 2/20$497
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/16:01 amMIA - BOC
1 stop12h 59mMultiple Airlines
jue. 5/82:30 pmBOC - MIA
2 stops21h 00mMultiple Airlines
Deal found 2/19$531
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/16:25 amMIA - DAV
2 stops36h 03mUnited Airlines
jue. 5/89:44 amDAV - MIA
1 stop6h 19mUnited Airlines
Deal found 2/19$1,047

Find flights from Key Largo to Panama within your budget

Customize your flight search to find flights from Key Largo to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated febrero 20, 2025.

Fly from

Key Largo

Fly to

Panama

Route

Depart

Return

Price

MiamiPanama City

MIA - PTY

MIAPTY

Miami

jue. 4/17

4:57 pm-2:14 pm

1 stop22h 17m

Panama City Tocumen Intl

dom. 5/25

7:55 am-10:45 pm

1 stop13h 50m

$286

MiamiPanama City

MIA - PTY

MIAPTY

Miami

jue. 3/13

7:20 pm-1:00 am

1 stop6h 40m

Panama City Tocumen Intl

sáb. 3/15

3:19 am-12:40 pm

1 stop8h 21m

$290

MiamiPanama City

MIA - PTY

MIAPTY

Miami

dom. 4/6

8:30 am-10:40 am

Nonstop3h 10m

Panama City Tocumen Intl

dom. 4/13

10:25 am-2:40 pm

Nonstop3h 15m

$293

MiamiDavid

MIA - DAV

MIADAV

Miami

dom. 3/30

6:18 am-5:26 pm

1 stop12h 08m

David Enrique Malek

sáb. 4/5

6:18 pm-1:38 am

1 stop6h 20m

$308

MiamiPanama City

MIA - PTY

MIAPTY

Miami

vie. 3/21

12:17 pm-2:32 pm

Nonstop3h 15m

Panama City Tocumen Intl

mié. 3/26

3:30 pm-7:35 pm

Nonstop3h 05m

$315

MiamiPanama City

MIA - PTY

MIAPTY

Miami

vie. 4/25

12:20 pm-2:30 pm

Nonstop3h 10m

Panama City Tocumen Intl

vie. 5/9

5:25 pm-4:00 am

1 stop9h 35m

$330

MiamiPanama City

MIA - PTY

MIAPTY

Miami

dom. 3/2

6:00 am-2:02 pm

1 stop8h 02m

Panama City Tocumen Intl

mié. 3/5

3:27 pm-12:51 am

1 stop9h 24m

$346

MiamiDavid

MIA - DAV

MIADAV

Miami

jue. 3/20

7:20 pm-3:00 pm

2 stops20h 40m

David Enrique Malek

jue. 3/27

9:41 am-4:44 pm

1 stop6h 03m

$497

MiamiBocas del Toro

MIA - BOC

MIABOC

Miami

jue. 5/1

6:01 am-6:00 pm

1 stop12h 59m

Bocas Del Toro

jue. 5/8

2:30 pm-12:30 pm

2 stops21h 00m

$531

MiamiDavid

MIA - DAV

MIADAV

Miami

jue. 5/1

6:25 am-5:28 pm

2 stops36h 03m

David Enrique Malek

jue. 5/8

9:44 am-5:03 pm

1 stop6h 19m

$1,047

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/19

Showing 1-10 of 19 results
1
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Best time to book a flight from Key Largo to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Key Largo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Key Largo to Panama

Get recent, data-driven insights about flights from Key Largo to Panama including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Key Largo to Panama?

Currently, October is the cheapest month in which you can book a flight from Key Largo to Panama (average of $478). Flying from Key Largo to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from KE9 to PA?

Find hourly flight availability from Key Largo to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated febrero 20, 2025.

When flying from Key Largo to Panama, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What is the cheapest day to fly from Key Largo to Panama?

Use this chart to determine the cheapest time to fly round-trip from Key Largo to Panama. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Key Largo to Panama flight should consider departing on Sunday evenings when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Key Largo to Panama

Explore weekly flight availability from Key Largo to Panama. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated febrero 20, 2025.

The most flights from KE9 to PA0 are scheduled on a Monday (16 on average). You will have fewer flight options on Friday, which is when the least amount of flights are scheduled (8 on average).

Rainfall in Panama by month

Plan your trip to Panama by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama when rainfall is around 0.4 in.

Temperature in Panama by month

Plan your trip to Panama by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated febrero 20, 2025.
Read through reviews of airlines operating flights from Key Largo to Panama, such as Delta, Copa Airlines and United Airlines. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
8,220 reviews

Crew

8.5

Overall

8.0

Boarding

8.2

Comfort

8.0

Entertainment

7.9

Food

7.3

Reviews

1 / 20

2.0
Mediocre

Santiago,Apr 2024

MCO - ATL

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.

Delta
8.0
Very good
8,220 reviews
Delta
8.0
Very good
8,220 reviews

Crew

8.5

Overall

8.0

Boarding

8.2

Comfort

8.0

Entertainment

7.9

Food

7.3

Reviews

1 / 20

2.0
Mediocre

Santiago,Apr 2024

MCO - ATL

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.

Copa Airlines
7.6
Good
1,510 reviews
Delta
8.0
Very good
8,220 reviews

Crew

8.5

Overall

8.0

Boarding

8.2

Comfort

8.0

Entertainment

7.9

Food

7.3

Reviews

1 / 20

2.0
Mediocre

Santiago,Apr 2024

MCO - ATL

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.

United Airlines
7.4
Good
8,766 reviews
Delta
8.0
Very good
8,220 reviews

Crew

8.5

Overall

8.0

Boarding

8.2

Comfort

8.0

Entertainment

7.9

Food

7.3

Reviews

1 / 20

2.0
Mediocre

Santiago,Apr 2024

MCO - ATL

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,220 reviews

Crew

8.5

Overall

8.0

Boarding

8.2

Comfort

8.0

Entertainment

7.9

Food

7.3

Reviews

1 / 20

2.0
Mediocre

Santiago,Apr 2024

MCO - ATL

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.

Avianca
6.8
Okay
2,435 reviews
Delta
8.0
Very good
8,220 reviews

Crew

8.5

Overall

8.0

Boarding

8.2

Comfort

8.0

Entertainment

7.9

Food

7.3

Reviews

1 / 20

2.0
Mediocre

Santiago,Apr 2024

MCO - ATL

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.

Related info for your journey

Find useful and relevant information for your journey from Key Largo to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Key Largo to Panama flight route?

    This flight path from Key Largo to Panama was viewed by 166 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines to fly from Key Largo to Panama one-way?

    The cheapest airlines for a one-way flight from Key Largo to Panama are Avianca ($127), Copa Airlines ($142), and United Airlines ($150).

  • What are the most popular routes from Key Largo to Panama?

    When deciding which route to take from Key Largo to Panama consider Miami - Panama City Tocumen Intl, Miami - David Enrique Malek or Miami - Bocas Del Toro as they are the most popular.

  • What are the most reliable airlines from Key Largo to Panama?

    The top 3 most reliable airlines when flying from Key Largo to Panama are Copa Airlines (92%), United Airlines (91%) and American Airlines (84%).

  • What are the cheapest flights from Key Largo to Panama?

    On average you can expect to pay $660 for a flight from Key Largo to Panama. The cheapest flight overall is $129 while the most popular route, (Miami - Panama City Tocumen Intl) is currently priced at $295.

  • Can I find deals for flights from Key Largo to Panama that include hotel bookings?

    Yes. In addition to deals on Key Largo to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Key Largo to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key Largo to Panama.

  • Can I find deals for business class flights from Key Largo to Panama?

    Yes. Cheapflights offers flight deals from Key Largo to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Key Largo to Panama?

    Currently, October is the cheapest month in which you can book a flight from Key Largo to Panama (average of $478). Flying from Key Largo to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Key Largo to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Key Largo to Panama

Discover the top 5 airlines that operate flights from Key Largo to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated febrero 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$247Average$385FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$269Average$374FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$297Average$415FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$301Average$507FlexibilityNo cancel feeOn-time69%
DeltaCheapest$311Average$531FlexibilityNo cancel feeOn-timeN/A
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