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$169+ Cheap flights from Irvine, CA to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/1. Fares are subject to change and may not be available on all flights or dates of travel.
LAX — PTY
Apr 22 — Apr 291
Tue 4/22
Tue 4/29
1 adult, Economy
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Cheap flight deals from Irvine to Panama

Keep the following information in mind while searching for Irvine to Panama flight deals. Data was last updated April 17, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$473
(Cheapflightsfares)

One-way from

$169
(Priceline)

Popular in

December

Cheapest in

August

Average price

$637
Provider with most accurate pricing for Los Angeles-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Los Angeles-Panama City Tocumen Intl flights.
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From Irvine to Panama
Search Deals
One-way flight from Irvine to Panama
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($34 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($12 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Irvine to Panama

Cheapest flights from Irvine to Panama
Explore the most affordable flight options available from Irvine to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/142:50 pmLAX - PTY
2 stops17h 35mAvianca
Tue 5/203:20 amPTY - LAX
2 stops21h 10mAvianca
Deal found 4/16$473
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1610:14 pmLAX - PTY
Nonstop6h 23mMultiple Airlines
Fri 5/235:25 pmPTY - LAX
2 stops22h 05mMultiple Airlines
Deal found 4/16$494
This Copa Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/152:10 amLAX - PTY
Nonstop6h 25mCopa Airlines
Fri 5/236:14 pmPTY - LAX
Nonstop7h 16mCopa Airlines
Deal found 4/17$519
This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1812:56 amLAX - PTY
1 stop15h 41mUnited Airlines
Fri 5/2310:00 amPTY - LAX
1 stop15h 05mUnited Airlines
Deal found 4/16$533
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/203:00 pmLAX - PTY
2 stops19h 48mDelta
Tue 5/272:13 pmPTY - LAX
1 stop20h 41mDelta
Deal found 4/16$578
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/183:18 pmLAX - PTY
1 stop20h 57mAmerican Airlines
Mon 7/211:50 pmPTY - LAX
2 stops19h 15mAmerican Airlines
Deal found 4/17$595
This Copa Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/312:03 pmLAX - DAV
1 stop18h 57mCopa Airlines
Sat 7/129:41 amDAV - LAX
1 stop9h 02mCopa Airlines
Deal found 4/17$827
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/312:03 pmLAX - DAV
1 stop17h 57mMultiple Airlines
Sat 7/128:30 amDAV - LAX
2 stops16h 00mMultiple Airlines
Deal found 4/17$876
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/245:50 pmLAX - DAV
2 stops37h 10mUnited Airlines
Thu 5/19:44 amDAV - LAX
1 stop15h 56mUnited Airlines
Deal found 4/17$1,281

Cheapflights Fare Finder

Customize your flight search to find flights from Irvine to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
Use the filters below to find and compare flights from Irvine to Panama that are best for you.

Fly from

Irvine

Fly to

Panama

Route

Depart

Return

Price

Los AngelesPanama City

LAX - PTY

LAXPTY

Los Angeles

Wed 5/14

2:50 pm-10:25 am

2 stops17h 35m

Panama City Tocumen Intl

Tue 5/20

3:20 am-10:30 pm

2 stops21h 10m

$473

Los AngelesPanama City

LAX - PTY

LAXPTY

Los Angeles

Fri 5/16

10:14 pm-6:37 am

Nonstop6h 23m

Panama City Tocumen Intl

Fri 5/23

5:25 pm-1:30 pm

2 stops22h 05m

$494

Los AngelesPanama City

LAX - PTY

LAXPTY

Los Angeles

Thu 5/15

2:10 am-10:35 am

Nonstop6h 25m

Panama City Tocumen Intl

Fri 5/23

6:14 pm-11:30 pm

Nonstop7h 16m

$519

Los AngelesPanama City

LAX - PTY

LAXPTY

Los Angeles

Sun 5/18

12:56 am-6:37 pm

1 stop15h 41m

Panama City Tocumen Intl

Fri 5/23

10:00 am-11:05 pm

1 stop15h 05m

$533

Los AngelesPanama City

LAX - PTY

LAXPTY

Los Angeles

Thu 5/15

7:52 pm-12:19 pm

2 stops14h 27m

Panama City Tocumen Intl

Sun 5/18

1:20 pm-8:31 am

2 stops21h 11m

$538

Los AngelesPanama City

LAX - PTY

LAXPTY

Los Angeles

Tue 5/20

3:00 pm-12:48 pm

2 stops19h 48m

Panama City Tocumen Intl

Thu 5/29

2:13 pm-10:00 am

2 stops21h 47m

$578

Los AngelesDavid

LAX - DAV

LAXDAV

Los Angeles

Thu 7/3

12:03 pm-9:00 am

1 stop18h 57m

David Enrique Malek

Sat 7/12

9:41 am-4:43 pm

1 stop9h 02m

$827

Los AngelesDavid

LAX - DAV

LAXDAV

Los Angeles

Thu 7/3

12:03 pm-8:00 am

1 stop17h 57m

David Enrique Malek

Sat 7/12

8:30 am-10:30 pm

2 stops16h 00m

$876

Los AngelesDavid

LAX - DAV

LAXDAV

Los Angeles

Thu 7/3

4:13 pm-9:00 am

2 stops14h 47m

David Enrique Malek

Sat 7/12

9:41 am-11:40 am

2 stops27h 59m

$1,687

Los AngelesPanama City

LAX - PTY

LAXPTY

Los Angeles

Tue 7/1

2:50 pm-10:25 am

2 stops17h 35m

$169

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/16

Showing 1-10 of 15 results
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Best time to book a flight from Irvine to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Irvine with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Irvine to Panama

What is the cheapest month to book a flight from Irvine to Panama?

Currently, October is the cheapest month in which you can book a flight from Irvine to Panama (average of $478). Flying from Irvine to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IR9 to PA?

Find hourly flight availability from Irvine to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 17, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Irvine to Panama as you normally would.

What is the cheapest day to fly from Irvine to Panama?

Use this chart to determine the cheapest time to fly round-trip from Irvine to Panama. Price data was last updated on June 30, 2024.

Travelers seeking maximum savings on their Irvine to Panama flight should consider departing on Wednesday mornings when fares are most often at their lowest. Monday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Irvine to Panama

Explore weekly flight availability from Irvine to Panama. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated April 17, 2025.

The most flights from IR9 to PA0 are scheduled on a Tuesday (9 on average). You will have fewer flight options on Friday, which is when the least amount of flights are scheduled (6 on average).

Rainfall in Panama by month

Plan your trip to Panama by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama when rainfall is around 0.4 in.

Temperature in Panama by month

Plan your trip to Panama by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated April 17, 2025.
See what other customers who have flown with Delta, Copa Airlines and United Airlines from Irvine to Panama have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,917 reviews

Food

7.3

Overall

8.0

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,917 reviews
Delta
8.0
Very good
7,917 reviews

Food

7.3

Overall

8.0

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.6
Good
1,409 reviews
Delta
8.0
Very good
7,917 reviews

Food

7.3

Overall

8.0

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,667 reviews
Delta
8.0
Very good
7,917 reviews

Food

7.3

Overall

8.0

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,917 reviews

Food

7.3

Overall

8.0

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Avianca
6.7
Okay
2,315 reviews
Delta
8.0
Very good
7,917 reviews

Food

7.3

Overall

8.0

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Irvine to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Irvine to Panama flight route?

    The Irvine to Panama flight path was viewed by 186 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines to fly from Irvine to Panama one-way?

    The cheapest airline one-way is Avianca, with whom users have recently found tickets for as low as $169. However, be on the lookout for offers from Copa Airlines and American Airlines, as they are both options that can get you from Irvine to Panama for a low price.

  • What are the most popular routes from Irvine to Panama?

    The most popular flight routes from Irvine to Panama are Los Angeles - Panama City Tocumen Intl, Los Angeles - David Enrique Malek and Los Angeles - Panama City Marcos A. Gelabert Intl.

  • What are the most reliable airlines from Irvine to Panama?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Irvine to Panama on time: EVA Air (93%), Asiana Airlines (93%), United Airlines (93%).

  • What are the cheapest flights from Irvine to Panama?

    Looking for the cheapest flight from Irvine to Panama? While on average our users pay $1,321, our data indicates the cheapest price to be $182. The most popular route (Los Angeles - Panama City Tocumen Intl), is priced around $413.

  • Can I find deals for flights from Irvine to Panama that include hotel bookings?

    Yes. In addition to deals on Irvine to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Irvine to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Irvine to Panama.

  • Can I find deals for business class flights from Irvine to Panama?

    Yes. Cheapflights offers flight deals from Irvine to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Irvine to Panama?

    Currently, October is the cheapest month in which you can book a flight from Irvine to Panama (average of $478). Flying from Irvine to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Irvine to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Irvine to Panama

Discover the top 5 airlines that operate flights from Irvine to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$292Average$635FlexibilityNo cancel feeOn-time71%
AviancaCheapest$330Average$481FlexibilityNo cancel feeOn-time71%
DeltaCheapest$373Average$601FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$380Average$661FlexibilityNo cancel feeOn-time69%
Copa AirlinesCheapest$467Average$681FlexibilityNo cancel feeOn-time70%

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