Panama

$188+ Cheap flights from Iowa to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/8. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — PTY
Apr 29 — May 61
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Iowa to Panama with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Iowa to Panama

Keep the following information in mind while searching for Iowa to Panama flight deals. Data was last updated April 24, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$441
(United Airlines)

One-way from

$188
(Delta)

Popular in

March

Cheapest in

August

Average price

$472
Provider with most accurate pricing for Des Moines-Panama City Tocumen Intl flight deals.
Provider most trusted by Cheapflights users for Des Moines-Panama City Tocumen Intl flights.
From Iowa to Panama
One-way flight from Iowa to Panama
Highest demand for flights based on searches. 18% potential increase in price ($116 potential increase over avg. RT price).
Cheapest flight prices on average. 6% potential price decrease ($31 potential savings vs. average RT price).
Average for round-trip flights in April 2025

Find flight deals from Iowa to Panama

Cheapest flights from Iowa to Panama
Explore the most affordable flight options available from Iowa to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2025.

This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/46:00 amDSM - PTY
1 stop10h 12mUnited Airlines
Wed 6/1110:00 amPTY - DSM
1 stop12h 22mUnited Airlines
Deal found 4/24$441
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/412:48 pmDSM - PTY
2 stops24h 12mAmerican Airlines
Wed 6/111:50 pmPTY - DSM
2 stops19h 17mAmerican Airlines
Deal found 4/24$448
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/76:30 amDSM - PTY
2 stops13h 23mDelta
Sat 6/142:23 pmPTY - DSM
2 stops30h 45mDelta
Deal found 4/23$461
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/275:35 amOMA - PTY
1 stop7h 12mDelta
Tue 11/43:12 pmPTY - OMA
1 stop9h 44mDelta
Deal found 4/23$501
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/275:15 pmOMA - PTY
2 stops25h 23mUnited Airlines
Tue 11/44:40 pmPTY - OMA
3 stops20h 23mUnited Airlines
Deal found 4/23$506
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/86:04 pmOMA - PTY
2 stops18h 56mAmerican Airlines
Sun 6/153:20 pmPTY - OMA
2 stops24h 07mAmerican Airlines
Deal found 4/23$617
This Mytrip deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/71:15 pmDSM - PTY
3 stops31h 55mMultiple Airlines
Sat 6/147:28 amPTY - DSM
3 stops39h 09mMultiple Airlines
Deal found 4/23$717
This Avianca deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/248:00 amDSM - PTY
2 stops31h 30mAvianca
Mon 12/293:19 amPTY - DSM
2 stops19h 17mAvianca
Deal found 4/23$2,451

Cheapflights Fare Finder

Customize your flight search to find flights from Iowa to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2025.
Use the filters below to find and compare flights from Iowa to Panama that are best for you.

Fly from

Iowa

Fly to

Panama

Route

Depart

Return

Price

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Wed 6/4

6:00 am-4:12 pm

1 stop10h 12m

Panama City Tocumen Intl

Wed 6/11

10:00 am-10:22 pm

1 stop12h 22m

$441

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Wed 6/4

12:48 pm-1:00 pm

2 stops24h 12m

Panama City Tocumen Intl

Wed 6/11

1:50 pm-9:07 am

2 stops19h 17m

$448

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Sat 6/7

6:30 am-7:53 pm

2 stops13h 23m

Panama City Tocumen Intl

Sat 6/14

2:23 pm-9:08 pm

2 stops30h 45m

$461

OmahaPanama City

OMA - PTY

OMAPTY

Omaha Eppley Airfield

Wed 6/4

8:25 am-4:12 pm

1 stop7h 47m

Panama City Tocumen Intl

Thu 6/12

10:00 am-7:22 pm

1 stop9h 22m

$521

OmahaPanama City

OMA - PTY

OMAPTY

Omaha Eppley Airfield

Sun 6/8

5:16 am-1:08 pm

1 stop7h 52m

Panama City Tocumen Intl

Sun 6/15

2:23 pm-12:25 am

1 stop10h 02m

$581

OmahaPanama City

OMA - PTY

OMAPTY

Omaha Eppley Airfield

Sun 6/8

6:04 pm-1:00 pm

2 stops18h 56m

Panama City Tocumen Intl

Sun 6/15

3:20 pm-3:27 pm

2 stops24h 07m

$617

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Sat 6/7

1:15 pm-9:10 pm

3 stops31h 55m

Panama City Tocumen Intl

Sat 6/14

7:28 am-10:37 pm

3 stops39h 09m

$717

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Sun 6/8

5:40 am-1:08 pm

1 stop7h 28m

$188

OmahaPanama City

OMA - PTY

OMAPTY

Omaha Eppley Airfield

Sun 5/4

6:15 am-2:14 pm

1 stop7h 59m

$346

OmahaPanama City

OMA - PTY

OMAPTY

Omaha Eppley Airfield

Sun 5/4

9:02 pm-8:15 am

3 stops35h 13m

$543

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/23

Best time to book a flight from Iowa to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Panama

What is the cheapest month to book a flight from Iowa to Panama?

Currently, October is the cheapest month in which you can book a flight from Iowa to Panama (average of $478). Flying from Iowa to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to PA?

Find hourly flight availability from Iowa to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 24, 2025.

When flying from Iowa to Panama, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Panama by month

Plan your trip to Panama by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama when rainfall is around 0.4 in.

Temperature in Panama by month

Plan your trip to Panama by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated April 24, 2025.
Read reviews from past customers who have flown Delta, United Airlines and American Airlines from Iowa to Panama. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
8.0
Very good

Comfort

7.9

Entertainment

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
8.0
Very good
8.0
Very good

Comfort

7.9

Entertainment

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
8.0
Very good

Comfort

7.9

Entertainment

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
8.0
Very good

Comfort

7.9

Entertainment

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • Can I find deals for flights from Iowa to Panama that include hotel bookings?

    Yes. In addition to deals on Iowa to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Panama.

  • Can I find deals for business class flights from Iowa to Panama?

    Yes. Cheapflights offers flight deals from Iowa to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Panama?

    Currently, October is the cheapest month in which you can book a flight from Iowa to Panama (average of $478). Flying from Iowa to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Iowa to Panama

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Iowa to Panama

Discover the top 3 airlines that operate flights from Iowa to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$349Average$623FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$349Average$518FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$354Average$544FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.