Panama

$173+ Cheap flights from Iowa to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/24. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — PTY
abr 9 — abr 161
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Cheap flight deals from Iowa to Panama

Keep the following information in mind while searching for Iowa to Panama flight deals. Data was last updated abril 4, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$441
(United Airlines)

One-way from

$173
(Delta)

Popular in

March

Cheapest in

August

Average price

$460
Provider with most accurate pricing for Des Moines-Panama City Tocumen Intl flight deals.
Provider most trusted by Cheapflights users for Des Moines-Panama City Tocumen Intl flights.
From Iowa to Panama
One-way flight from Iowa to Panama
Highest demand for flights based on searches. 16% potential increase in price ($93 potential increase over avg. RT price).
Cheapest flight prices on average. 4% potential price decrease ($22 potential savings vs. average RT price).
Average for round-trip flights in April 2025

Find flight deals from Iowa to Panama

Cheapest flights from Iowa to Panama
Explore the most affordable flight options available from Iowa to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on abril 4, 2025.

This United Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb 4/128:00 amDSM - PTY
1 stop10h 37mUnited Airlines
dom 4/207:55 amPTY - DSM
1 stop14h 50mUnited Airlines
Deal found 4/3$411
This American Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb 5/242:20 pmDSM - PTY
2 stops21h 59mAmerican Airlines
sáb 5/311:20 pmPTY - DSM
2 stops22h 58mAmerican Airlines
Deal found 4/3$481
This Delta deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb 5/246:30 amDSM - PTY
2 stops13h 23mDelta
sáb 5/318:00 amPTY - DSM
1 stop9h 50mDelta
Deal found 4/3$486
This United Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb 4/265:20 pmOMA - PTY
2 stops20h 54mUnited Airlines
qua 4/303:20 pmPTY - OMA
2 stops19h 04mUnited Airlines
Deal found 4/3$488
This Delta deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
seg 10/275:35 amOMA - PTY
1 stop7h 12mDelta
ter 11/43:12 pmPTY - OMA
1 stop9h 44mDelta
Deal found 4/3$501
This American Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
seg 10/274:11 pmOMA - PTY
2 stops20h 14mAmerican Airlines
ter 11/44:20 pmPTY - OMA
1 stop8h 30mAmerican Airlines
Deal found 4/3$506
This CheapTickets.ch deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapTickets.ch is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 5/186:45 amDSM - PTY
2 stops29h 34mBritish Airways
dom 5/251:20 pmPTY - DSM
2 stops23h 01mBritish Airways
Deal found 4/2$548
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
seg 5/195:30 amCID - PTY
1 stop7h 18mDelta
seg 5/262:13 pmPTY - CID
1 stop8h 47mDelta
Deal found 4/4$558
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
seg 5/194:30 pmCID - PTY
2 stops19h 49mAmerican Airlines
seg 5/261:20 pmPTY - CID
2 stops21h 38mAmerican Airlines
Deal found 4/4$578
This CheapTickets.ch deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapTickets.ch is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 5/188:00 amDSM - PTY
1 stop8h 12mLufthansa
dom 5/2510:00 amPTY - DSM
1 stop12h 22mLufthansa
Deal found 4/2$664
This Mytrip deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 5/1812:32 pmDSM - PTY
3 stops31h 18mMultiple Airlines
dom 5/2511:05 amPTY - DSM
3 stops26h 48mMultiple Airlines
Deal found 4/2$681
This Mytrip deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
seg 5/196:58 pmCID - PTY
3 stops41h 37mMultiple Airlines
dom 5/253:20 amPTY - CID
2 stops14h 48mMultiple Airlines
Deal found 4/4$748

Cheapflights Fare Finder

Customize your flight search to find flights from Iowa to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 4, 2025.
Use the filters below to find and compare flights from Iowa to Panama that are best for you.

Fly from

Iowa

Fly to

Panama

Route

Depart

Return

Price

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

ter 7/1

6:02 am-2:14 pm

1 stop8h 12m

Panama City Tocumen Intl

sáb 7/5

10:00 am-10:17 pm

1 stop12h 17m

$441

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

sáb 5/24

2:20 pm-12:19 pm

2 stops21h 59m

Panama City Tocumen Intl

sáb 5/31

1:20 pm-12:18 pm

2 stops22h 58m

$481

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

sáb 5/24

6:30 am-7:53 pm

2 stops13h 23m

Panama City Tocumen Intl

sáb 5/31

8:00 am-5:50 pm

1 stop9h 50m

$486

OmahaPanama City

OMA - PTY

OMAPTY

Omaha Eppley Airfield

sáb 4/26

5:20 pm-2:14 pm

2 stops20h 54m

Panama City Tocumen Intl

qua 4/30

3:20 pm-10:24 am

2 stops19h 04m

$488

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

dom 5/18

6:45 am-12:19 pm

2 stops29h 34m

Panama City Tocumen Intl

dom 5/25

1:20 pm-12:21 pm

2 stops23h 01m

$548

Cedar RapidsPanama City

CID - PTY

CIDPTY

Cedar Rapids

seg 5/19

5:30 am-12:48 pm

1 stop7h 18m

Panama City Tocumen Intl

seg 5/26

2:13 pm-11:00 pm

1 stop8h 47m

$558

OmahaPanama City

OMA - PTY

OMAPTY

Omaha Eppley Airfield

qua 6/18

6:04 pm-1:00 pm

2 stops18h 56m

Panama City Tocumen Intl

dom 6/22

3:20 pm-10:50 am

2 stops19h 30m

$566

Cedar RapidsPanama City

CID - PTY

CIDPTY

Cedar Rapids

seg 5/19

4:30 pm-12:19 pm

2 stops19h 49m

Panama City Tocumen Intl

seg 5/26

1:20 pm-10:58 am

2 stops21h 38m

$578

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

dom 5/18

8:00 am-4:12 pm

1 stop8h 12m

Panama City Tocumen Intl

dom 5/25

10:00 am-10:22 pm

1 stop12h 22m

$664

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

dom 5/18

12:32 pm-7:50 pm

3 stops31h 18m

Panama City Tocumen Intl

dom 5/25

11:05 am-1:53 pm

3 stops26h 48m

$681

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/2

Showing 1-10 of 14 results
1
2

Best time to book a flight from Iowa to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Panama

What is the cheapest month to book a flight from Iowa to Panama?

Currently, October is the cheapest month in which you can book a flight from Iowa to Panama (average of $478). Flying from Iowa to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to PA?

Find hourly flight availability from Iowa to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated abril 4, 2025.

When flying from Iowa to Panama, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Panama by month

Plan your trip to Panama by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama when rainfall is around 0.4 in.

Temperature in Panama by month

Plan your trip to Panama by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated abril 4, 2025.
Read reviews from past customers who have flown Delta, United Airlines and American Airlines from Iowa to Panama. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
8.0
Very good

Overall

8.0

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
8.0
Very good
8.0
Very good

Overall

8.0

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
8.0
Very good

Overall

8.0

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
8.0
Very good

Overall

8.0

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
8.0
Very good

Overall

8.0

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
8.0
Very good

Overall

8.0

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • Can I find deals for flights from Iowa to Panama that include hotel bookings?

    Yes. In addition to deals on Iowa to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Panama.

  • Can I find deals for business class flights from Iowa to Panama?

    Yes. Cheapflights offers flight deals from Iowa to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Panama?

    Currently, October is the cheapest month in which you can book a flight from Iowa to Panama (average of $478). Flying from Iowa to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Iowa to Panama

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Iowa to Panama

Discover the top 3 airlines that operate flights from Iowa to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$349Average$693FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$349Average$513FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$354Average$544FlexibilityNo cancel feeOn-time71%

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