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$168+ Cheap flights from Indiana to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/20. Fares are subject to change and may not be available on all flights or dates of travel.
IND — PTY
Apr 29 — May 61
Tue 4/29
Tue 5/6
1 adult, Economy
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Cheap flight deals from Indiana to Panama

Keep the following information in mind while searching for Indiana to Panama flight deals. Data was last updated April 24, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$403
(Delta)

One-way from

$168
(Kiwi.com)

Popular in

December

Cheapest in

October

Average price

$623
Provider with most accurate pricing for Indianapolis-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Indianapolis-Panama City Tocumen Intl flights.
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From Indiana to Panama
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One-way flight from Indiana to Panama
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Highest demand for flights based on searches. 5% potential increase in price ($32 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Indiana to Panama

Cheapest flights from Indiana to Panama
Explore the most affordable flight options available from Indiana to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2025.

This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/276:00 amSDF - PTY
1 stop7h 48mDelta
Tue 6/32:13 pmPTY - SDF
1 stop8h 52mDelta
Deal found 4/22$403
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/287:00 amSDF - PTY
2 stops12h 37mUnited Airlines
Mon 6/163:20 pmPTY - SDF
2 stops17h 13mUnited Airlines
Deal found 4/24$408
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/247:24 pmSDF - PTY
2 stops19h 51mAmerican Airlines
Sun 7/273:05 pmPTY - SDF
2 stops18h 20mAmerican Airlines
Deal found 4/22$422
This Copa Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/13:07 pmORD - PTY
Nonstop5h 28mCopa Airlines
Wed 6/46:45 pmPTY - ORD
Nonstop5h 49mCopa Airlines
Deal found 4/22$465
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/209:55 amORD - PTY
2 stops28h 45mMultiple Airlines
Sun 5/253:20 amPTY - ORD
1 stop9h 55mMultiple Airlines
Deal found 4/23$466
This Gotogate deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/32:35 pmORD - PTY
1 stop9h 35mAvianca
Tue 6/103:40 pmPTY - ORD
2 stops22h 45mAvianca
Deal found 4/22$467
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/17:15 amCVG - PTY
1 stop6h 39mDelta
Mon 9/82:14 pmPTY - CVG
1 stop7h 26mDelta
Deal found 4/22$469
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/36:00 amIND - PTY
1 stop8h 08mDelta
Thu 7/102:12 pmPTY - IND
1 stop8h 45mDelta
Deal found 4/23$469
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/176:45 amCVG - PTY
1 stop12h 52mUnited Airlines
Tue 6/243:20 pmPTY - CVG
2 stops20h 48mUnited Airlines
Deal found 4/23$474
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/1411:20 amORD - PTY
1 stop7h 42mDelta
Wed 6/182:23 pmPTY - ORD
2 stops17h 26mDelta
Deal found 4/22$474
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/225:40 pmIND - PTY
2 stops19h 45mAmerican Airlines
Wed 10/291:50 pmPTY - IND
1 stop9h 04mAmerican Airlines
Deal found 4/23$474
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/206:00 amMDW - PTY
1 stop6h 48mDelta
Sun 5/258:00 amPTY - MDW
1 stop13h 27mDelta
Deal found 4/23$479

Cheapflights Fare Finder

Customize your flight search to find flights from Indiana to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2025.
Use the filters below to find and compare flights from Indiana to Panama that are best for you.

Fly from

Indiana

Fly to

Panama

Route

Depart

Return

Price

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Tue 5/27

6:00 am-12:48 pm

1 stop7h 48m

Panama City Tocumen Intl

Tue 6/3

2:13 pm-12:05 am

1 stop8h 52m

$403

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Wed 5/28

7:00 am-6:37 pm

2 stops12h 37m

Panama City Tocumen Intl

Mon 6/16

3:20 pm-9:33 am

2 stops17h 13m

$408

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Thu 7/24

7:24 pm-2:15 pm

2 stops19h 51m

Panama City Tocumen Intl

Sun 7/27

3:05 pm-10:25 am

2 stops18h 20m

$422

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Sun 6/1

3:07 pm-8:35 pm

Nonstop5h 28m

Panama City Tocumen Intl

Wed 6/4

6:45 pm-12:34 am

Nonstop5h 49m

$465

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Tue 5/20

9:55 am-2:40 pm

2 stops28h 45m

Panama City Tocumen Intl

Sun 5/25

3:20 am-1:15 pm

1 stop9h 55m

$466

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Tue 6/3

2:35 pm-12:10 am

1 stop9h 35m

Panama City Tocumen Intl

Tue 6/10

3:40 pm-2:25 pm

2 stops22h 45m

$467

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Thu 7/3

6:00 am-1:08 pm

1 stop8h 08m

Panama City Tocumen Intl

Thu 7/10

2:12 pm-11:57 pm

1 stop8h 45m

$469

CincinnatiPanama City

CVG - PTY

CVGPTY

Cincinnati Cinci./N. Kentucky

Tue 6/17

6:45 am-6:37 pm

1 stop12h 52m

Panama City Tocumen Intl

Tue 6/24

3:20 pm-1:08 pm

2 stops20h 48m

$474

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Tue 5/20

8:15 am-12:10 am

2 stops16h 55m

Panama City Tocumen Intl

Mon 5/26

3:25 am-11:15 pm

2 stops18h 50m

$474

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Sat 6/14

11:20 am-7:02 pm

1 stop7h 42m

Panama City Tocumen Intl

Wed 6/18

2:23 pm-7:49 am

2 stops17h 26m

$474

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/22

Showing 1-10 of 43 results
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Best time to book a flight from Indiana to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Indiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indiana to Panama

What is the cheapest month to book a flight from Indiana to Panama?

Currently, October is the cheapest month in which you can book a flight from Indiana to Panama (average of $478). Flying from Indiana to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IN to PA?

Find hourly flight availability from Indiana to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 24, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Indiana to Panama as you normally would.

Rainfall in Panama by month

Plan your trip to Panama by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama when rainfall is around 0.4 in.

Temperature in Panama by month

Plan your trip to Panama by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated April 24, 2025.
Read reviews from past customers who have flown Delta, Copa Airlines and United Airlines from Indiana to Panama. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,920 reviews

Entertainment

7.9

Comfort

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,920 reviews
Delta
8.0
Very good
7,920 reviews

Entertainment

7.9

Comfort

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.6
Good
1,411 reviews
Delta
8.0
Very good
7,920 reviews

Entertainment

7.9

Comfort

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,685 reviews
Delta
8.0
Very good
7,920 reviews

Entertainment

7.9

Comfort

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,920 reviews

Entertainment

7.9

Comfort

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Avianca
6.7
Okay
2,319 reviews
Delta
8.0
Very good
7,920 reviews

Entertainment

7.9

Comfort

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Indiana to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Indiana to Panama one-way?

    One-way options have recently been found by users for as low as $203 on Avianca. Other airlines that offer cheap prices include American Airlines from $238 and United Airlines from $242 one-way.

  • Can I find deals for flights from Indiana to Panama that include hotel bookings?

    Yes. In addition to deals on Indiana to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indiana to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indiana to Panama.

  • Can I find deals for business class flights from Indiana to Panama?

    Yes. Cheapflights offers flight deals from Indiana to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indiana to Panama?

    Currently, October is the cheapest month in which you can book a flight from Indiana to Panama (average of $478). Flying from Indiana to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Indiana to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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O'Hare Intl to Panama City flights
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George Bush Intcntl to San José flights
Dallas/Fort Worth to San José flights
George Bush Intcntl to Guatemala City flights
Miami to San Salvador flights
LaGuardia to Guatemala City flights
Atlanta to Guatemala City flights
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LaGuardia to Liberia flights
Ontario to Guatemala City flights
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Top 3 airlines flying from Indiana to Panama

Discover the top 3 airlines that operate flights from Indiana to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$286Average$541FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$463Average$634FlexibilityNo cancel feeOn-time71%
DeltaCheapest$469Average$587FlexibilityNo cancel feeOn-timeN/A

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