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$359+ Cheap flights from Greenville (GSP) to Panama

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/1. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — PTY
Apr 2 — Apr 91
Wed 4/2
Wed 4/9
1 adult, Economy
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Cheap flight deals from Greenville to Panama

Keep the following information in mind while searching for Greenville to Panama flight deals. Data was last updated March 28, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$359
(Delta)

Popular in

March

Cheapest in

November

Average price

$603
Provider with most accurate pricing for Greenville-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Greenville-Panama City Tocumen Intl flights.
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From Greenville to Panama
Search Deals
Highest demand for flights based on searches. 15% potential increase in price ($76 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($17 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Find flight deals from Greenville to Panama

Cheapest flights from Greenville to Panama
Explore the most affordable flight options available from Greenville to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 28, 2025.

This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/15:47 amGSP - PTY
1 stop8h 08mDelta
Wed 4/22:20 pmPTY - GSP
1 stop6h 54mDelta
Deal found 3/26$359
This American Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/16:39 amGSP - PTY
2 stops9h 01mAmerican Airlines
Wed 4/23:50 pmPTY - GSP
2 stops17h 57mAmerican Airlines
Deal found 3/26$364
This United Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/17:05 amGSP - PTY
1 stop8h 09mUnited Airlines
Tue 4/83:20 pmPTY - GSP
1 stop23h 01mUnited Airlines
Deal found 3/27$367
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/314:35 pmGSP - PTY
2 stops25h 17mMultiple Airlines
Sun 4/612:03 pmPTY - GSP
1 stop26h 01mMultiple Airlines
Deal found 3/27$766
This KAYAK deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/109:30 amGSP - PTY
2 stops15h 40mAvianca
Mon 6/163:25 amPTY - GSP
2 stops18h 18mAvianca
Deal found 3/27$1,094

Cheapflights Fare Finder

Customize your flight search to find flights from Greenville to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
Use the filters below to find and compare flights from Greenville to Panama that are best for you.

Fly from

Greenville

Fly to

Panama

Route

Depart

Return

Price

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Thu 5/8

5:30 am-12:48 pm

1 stop8h 18m

Panama City Tocumen Intl

Thu 5/15

2:13 pm-11:52 pm

1 stop8h 39m

$359

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Mon 5/5

6:36 pm-12:19 pm

2 stops18h 43m

Panama City Tocumen Intl

Thu 5/8

1:20 pm-8:33 am

2 stops18h 13m

$364

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Mon 5/5

11:26 am-7:31 pm

1 stop9h 05m

Panama City Tocumen Intl

Thu 5/8

3:20 pm-10:15 pm

1 stop29h 55m

$406

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Mon 6/16

2:50 pm-9:10 pm

2 stops31h 20m

Panama City Tocumen Intl

Sat 6/21

3:20 am-4:22 pm

3 stops36h 02m

$989

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Tue 6/10

9:30 am-12:10 am

2 stops15h 40m

Panama City Tocumen Intl

Mon 6/16

3:25 am-10:43 pm

2 stops18h 18m

$1,094

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/26

Best time to book a flight from Greenville to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to Panama

What is the cheapest month to book a flight from Greenville to Panama?

Currently, October is the cheapest month in which you can book a flight from Greenville to Panama (average of $478). Flying from Greenville to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GSP to PA?

Find hourly flight availability from Greenville to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 28, 2025.

When flying from Greenville to Panama, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Panama by month

Plan your trip to Panama by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama when rainfall is around 0.4 in.

Temperature in Panama by month

Plan your trip to Panama by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated March 28, 2025.
Delta
8.0
Very good
7,896 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Comfort

8.0

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,896 reviews
Delta
8.0
Very good
7,896 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Comfort

8.0

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,603 reviews
Delta
8.0
Very good
7,896 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Comfort

8.0

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,896 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Comfort

8.0

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Avianca
6.7
Okay
2,300 reviews
Delta
8.0
Very good
7,896 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Comfort

8.0

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Greenville to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Greenville to Panama?

    Greenville (GSP), located 10.4 mi from the city center, is the airport you fly out of when you book flights from Greenville to Panama.

  • Can I find deals for flights from Greenville to Panama that include hotel bookings?

    Yes. In addition to deals on Greenville to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Panama.

  • Can I find deals for business class flights from Greenville to Panama?

    Yes. Cheapflights offers flight deals from Greenville to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to Panama?

    Currently, October is the cheapest month in which you can book a flight from Greenville to Panama (average of $478). Flying from Greenville to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Greenville to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Savannah to Guatemala City flights
Hilton Head Island to San José flights
Augusta to Panama City flights
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Augusta to Guatemala City flights
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Top 3 airlines flying from Greenville to Panama

Discover the top 3 airlines that operate flights from Greenville to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$281Average$380FlexibilityNo cancel feeOn-time69%
DeltaCheapest$351Average$603FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$352Average$577FlexibilityNo cancel feeOn-time71%
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