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$260+ Cheap flights from Colorado to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/21. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — PTY
Apr 7 — Apr 141
Mon 4/7
Mon 4/14
1 adult, Economy
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Cheap flight deals from Colorado to Panama

Keep the following information in mind while searching for Colorado to Panama flight deals. Data was last updated April 2, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$493
(Copa Airlines)

One-way from

$260
(Kiwi.com)

Popular in

December

Cheapest in

October

Average price

$632

Good round-trip deal

$482 or less

Good one-way deal

$205 or less
Provider with most accurate pricing for Denver Intl-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Denver Intl-Panama City Tocumen Intl flights.
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From Colorado to Panama
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One-way flight from Colorado to Panama
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Highest demand for flights based on searches. 11% potential increase in price ($76 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($23 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Price to beat on a round-trip flight from Colorado to Panama.
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Price to beat on a one-way flight from Colorado to Panama.
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Find flight deals from Colorado to Panama

Cheapest flights from Colorado to Panama
Explore the most affordable flight options available from Colorado to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 2, 2025.

This Copa Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/3010:25 pmDEN - PTY
Nonstop5h 46mCopa Airlines
Wed 5/712:56 pmPTY - DEN
Nonstop6h 21mCopa Airlines
Deal found 4/1$493
This Kiwi.com deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/3010:53 pmDEN - PTY
1 stop20h 46mMultiple Airlines
Mon 5/55:25 pmPTY - DEN
2 stops16h 04mMultiple Airlines
Deal found 4/1$501
This United deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/285:00 amDEN - PTY
1 stop10h 12mUnited Airlines
Wed 6/1110:00 amPTY - DEN
1 stop13h 29mUnited Airlines
Deal found 4/2$507
This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/36:31 pmDEN - PTY
2 stops18h 54mAmerican Airlines
Mon 7/141:50 pmPTY - DEN
2 stops20h 46mAmerican Airlines
Deal found 4/2$512
This United Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/215:24 pmCOS - PTY
2 stops19h 50mUnited Airlines
Fri 4/253:20 pmPTY - COS
2 stops18h 39mUnited Airlines
Deal found 4/1$526
This Delta deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1412:59 amDEN - PTY
1 stop10h 55mDelta
Sat 11/88:05 amPTY - DEN
1 stop14h 15mDelta
Deal found 4/2$623
This Avianca deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/146:00 amDEN - PTY
2 stops14h 10mAvianca
Sun 8/173:20 amPTY - DEN
2 stops17h 11mAvianca
Deal found 4/1$912

Cheapflights Fare Finder

Customize your flight search to find flights from Colorado to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 2, 2025.
Use the filters below to find and compare flights from Colorado to Panama that are best for you.

Fly from

Colorado

Fly to

Panama

Route

Depart

Return

Price

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Wed 4/30

10:25 pm-5:11 am

Nonstop5h 46m

Panama City Tocumen Intl

Wed 5/7

12:56 pm-6:17 pm

Nonstop6h 21m

$493

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Wed 4/30

10:53 pm-8:39 pm

1 stop20h 46m

Panama City Tocumen Intl

Mon 5/5

5:25 pm-8:29 am

2 stops16h 04m

$501

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Wed 5/28

5:00 am-4:12 pm

1 stop10h 12m

Panama City Tocumen Intl

Wed 6/11

10:00 am-10:29 pm

1 stop13h 29m

$507

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Thu 7/3

6:31 pm-2:25 pm

2 stops18h 54m

Panama City Tocumen Intl

Mon 7/14

1:50 pm-9:36 am

2 stops20h 46m

$512

Colorado SpringsPanama City

COS - PTY

COSPTY

Colorado Springs

Mon 4/21

5:24 pm-2:14 pm

2 stops19h 50m

Panama City Tocumen Intl

Fri 4/25

3:20 pm-8:59 am

2 stops18h 39m

$526

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Thu 8/14

12:59 am-12:54 pm

1 stop10h 55m

Panama City Tocumen Intl

Sat 11/8

8:05 am-8:20 pm

1 stop14h 15m

$623

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Thu 8/14

6:00 am-9:10 pm

2 stops14h 10m

Panama City Tocumen Intl

Sun 8/17

3:20 am-7:31 pm

2 stops17h 11m

$912

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Mon 4/21

10:59 pm-2:40 pm

2 stops14h 41m

$260

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sun 4/20

5:20 am-4:12 pm

1 stop9h 52m

$582

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Tue 4/8

12:55 am-12:58 pm

1 stop11h 03m

$698

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/31

Showing 1-10 of 14 results
1
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Best time to book a flight from Colorado to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Colorado with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Colorado to Panama

What is the cheapest month to book a flight from Colorado to Panama?

Currently, October is the cheapest month in which you can book a flight from Colorado to Panama (average of $478). Flying from Colorado to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CO to PA?

Find hourly flight availability from Colorado to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 2, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Colorado to Panama as you normally would.

Rainfall in Panama by month

Plan your trip to Panama by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama when rainfall is around 0.4 in.

Temperature in Panama by month

Plan your trip to Panama by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated April 2, 2025.
Read through reviews of airlines operating flights from Colorado to Panama, such as Delta, Copa Airlines and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,898 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,898 reviews
Delta
8.0
Very good
7,898 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.6
Good
1,400 reviews
Delta
8.0
Very good
7,898 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,616 reviews
Delta
8.0
Very good
7,898 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,898 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Avianca
6.7
Okay
2,302 reviews
Delta
8.0
Very good
7,898 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Colorado to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Colorado to Panama flight route?

    The Colorado to Panama flight path was viewed by 49 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines to fly from Colorado to Panama one-way?

    One-way options have recently been found by users for as low as $582 on United Airlines. Other airlines that offer cheap prices include Delta from $698 and American Airlines from $953 one-way.

  • Can I find deals for flights from Colorado to Panama that include hotel bookings?

    Yes. In addition to deals on Colorado to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Colorado to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Colorado to Panama.

  • Can I find deals for business class flights from Colorado to Panama?

    Yes. Cheapflights offers flight deals from Colorado to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Colorado to Panama?

    Currently, October is the cheapest month in which you can book a flight from Colorado to Panama (average of $478). Flying from Colorado to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Colorado to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Colorado to Panama

Discover the top 4 airlines that operate flights from Colorado to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 2, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$361Average$623FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$473Average$663FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$477Average$660FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$518Average$692FlexibilityNo cancel feeOn-time69%

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