HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Panama

$222+ Cheap flights from Cleveland (CLE) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/8. Fares are subject to change and may not be available on all flights or dates of travel.
CLE — PTY
Apr 2 — Apr 91
Wed 4/2
Wed 4/9
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Cleveland to Panama with Cheapflights

1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”
2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.
3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Cleveland to Panama

Keep the following information in mind while searching for Cleveland to Panama flight deals. Data was last updated March 28, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$411
(Kiwi.com)

One-way from

$222
(Delta)

Popular in

December

Cheapest in

September

Average price

$612
Provider with most accurate pricing for Cleveland Hopkins Intl-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Cleveland Hopkins Intl-Panama City Tocumen Intl flights.
Search Deals
From Cleveland Hopkins Intl to Panama
Search Deals
One-way flight from Cleveland Hopkins Intl to Panama
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($29 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($16 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2025
Search Deals

Find flight deals from Cleveland to Panama

Cheapest flights from Cleveland to Panama
Explore the most affordable flight options available from Cleveland to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 28, 2025.

This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/281:37 pmCLE - PTY
1 stop8h 00mMultiple Airlines
Fri 5/210:25 amPTY - CLE
1 stop7h 59mMultiple Airlines
Deal found 3/27$411
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/286:52 pmCLE - PTY
2 stops18h 23mAmerican Airlines
Fri 5/21:15 pmPTY - CLE
2 stops21h 46mAmerican Airlines
Deal found 3/27$460
This United Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/112:35 pmCLE - PTY
1 stop26h 37mUnited Airlines
Sun 5/183:20 pmPTY - CLE
1 stop19h 15mUnited Airlines
Deal found 3/27$465
This Expedia deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1110:40 amCLE - PTY
2 stops35h 30mAvianca
Sat 5/173:20 amPTY - CLE
2 stops29h 24mAvianca
Deal found 3/27$979
This Delta deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/201:00 pmCLE - PTY
1 stop7h 02mDelta
Sat 12/278:10 amPTY - CLE
1 stop9h 03mDelta
Deal found 3/27$1,066

Cheapflights Fare Finder

Customize your flight search to find flights from Cleveland to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
Use the filters below to find and compare flights from Cleveland to Panama that are best for you.

Fly from

Cleveland

Fly to

Panama

Route

Depart

Return

Price

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Mon 4/28

1:37 pm-8:37 pm

1 stop8h 00m

Panama City Tocumen Intl

Fri 5/2

10:25 am-7:24 pm

1 stop7h 59m

$411

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Mon 4/28

6:52 pm-12:15 pm

2 stops18h 23m

Panama City Tocumen Intl

Fri 5/2

1:15 pm-12:01 pm

2 stops21h 46m

$460

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Sun 5/11

2:35 pm-4:12 pm

1 stop26h 37m

Panama City Tocumen Intl

Sun 5/18

3:20 pm-11:35 am

1 stop19h 15m

$465

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Sun 5/11

10:40 am-9:10 pm

2 stops35h 30m

Panama City Tocumen Intl

Sat 5/17

3:20 am-9:44 am

2 stops29h 24m

$979

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Tue 7/8

6:00 am-12:54 pm

1 stop7h 54m

$222

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Mon 7/7

5:53 pm-12:54 pm

2 stops20h 01m

$228

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Sat 5/3

2:49 pm-1:20 pm

3 stops23h 31m

$288

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Tue 7/8

6:05 am-12:35 pm

3 stops31h 30m

$784

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/27

Best time to book a flight from Cleveland to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Cleveland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Cleveland to Panama

What is the cheapest month to book a flight from Cleveland to Panama?

Currently, October is the cheapest month in which you can book a flight from Cleveland to Panama (average of $478). Flying from Cleveland to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CLE to PA?

Find hourly flight availability from Cleveland to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 28, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Cleveland to Panama as you normally would.

Rainfall in Panama by month

Plan your trip to Panama by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama when rainfall is around 0.4 in.

Temperature in Panama by month

Plan your trip to Panama by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated March 28, 2025.
Delta
8.0
Very good
7,896 reviews

Entertainment

7.9

Comfort

8.0

Boarding

8.2

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,896 reviews
Delta
8.0
Very good
7,896 reviews

Entertainment

7.9

Comfort

8.0

Boarding

8.2

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,603 reviews
Delta
8.0
Very good
7,896 reviews

Entertainment

7.9

Comfort

8.0

Boarding

8.2

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,896 reviews

Entertainment

7.9

Comfort

8.0

Boarding

8.2

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Avianca
6.7
Okay
2,300 reviews
Delta
8.0
Very good
7,896 reviews

Entertainment

7.9

Comfort

8.0

Boarding

8.2

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Cleveland to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Cleveland to Panama?

    Cleveland Hopkins Intl (CLE) is the airport you will fly out of if you book a flight from Cleveland to Panama. It is only a 10.1 mi journey to Hopkins Intl (CLE) from Cleveland’s city center.

  • What are the cheapest airlines to fly from Cleveland to Panama one-way?

    To fly one-way, consider booking your trip with Delta, which is currently one of the cheapest options available, starting at $222. American Airlines flights start at $228 while deals on Avianca start at $784 one-way.

  • Can I find deals for flights from Cleveland to Panama that include hotel bookings?

    Yes. In addition to deals on Cleveland to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cleveland to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cleveland to Panama.

  • Can I find deals for business class flights from Cleveland to Panama?

    Yes. Cheapflights offers flight deals from Cleveland to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cleveland to Panama?

    Currently, October is the cheapest month in which you can book a flight from Cleveland to Panama (average of $478). Flying from Cleveland to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Cleveland to Panama

See prices for flight routes from nearby airports that may be better suited for you.
Columbus to San José flights
Cincinnati to San José flights
Detroit to San José flights
Cleveland to Philip S.W.Goldson flights
Cleveland to San José flights
Detroit to Liberia flights
Cincinnati to Panama City flights
Pittsburgh to Liberia flights
Cincinnati to Philip S.W.Goldson flights
Detroit to Philip S.W.Goldson flights
Pittsburgh to Philip S.W.Goldson flights
Pittsburgh to San José flights
Cleveland to Guatemala City flights
Columbus to Panama City flights
Columbus to Liberia flights
Detroit to Guatemala City flights
Columbus to Philip S.W.Goldson flights
Detroit to Coxen Hole flights
Cleveland to Liberia flights
Pittsburgh to Panama City flights
Detroit to Panama City flights
Columbus to Guatemala City flights
Detroit to San Pedro Sula flights
Cincinnati to Coxen Hole flights
Cincinnati to Liberia flights
Detroit to San Salvador flights
Cleveland to San Salvador flights
Cincinnati to Guatemala City flights
Dayton to San José flights
Cincinnati to Managua flights
Columbus to San Salvador flights
Cincinnati to San Salvador flights
Columbus to Coxen Hole flights
Pittsburgh to San Salvador flights
Detroit to Managua flights
Cleveland to San Pedro Sula flights
Columbus to San Pedro Sula flights
Pittsburgh to Guatemala City flights
Cleveland to Panama City flights
Dayton to Philip S.W.Goldson flights
Dayton to Panama City flights
Akron to Philip S.W.Goldson flights
Cleveland to Coxen Hole flights
Cleveland to Managua flights
Cincinnati to San Pedro Sula flights
Columbus to Managua flights
Akron to San José flights
Akron to Panama City flights
Dayton to Managua flights
Pittsburgh to Coxen Hole flights

Top 3 airlines flying from Cleveland to Panama

Discover the top 3 airlines that operate flights from Cleveland to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$384Average$646FlexibilityNo cancel feeOn-time71%
DeltaCheapest$449Average$563FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$459Average$619FlexibilityNo cancel feeOn-time69%
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.